968 resultados para Research Subject Categories::MEDICINE::Surgery::Oncology


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Print ceases at v.48 (2007), then becomes online only.

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Originally issued Feb. 1957.

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Originally issued 1957.

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Background: The Functional Capacity Index (FCI) was designed to predict physical function 12 months after injury. We report a validation study of the FCI. Methods: This was a consecutive case series registered in the Queensland Trauma Registry who consented to the prospective 12-month telephone-administered follow-up study. FCI scores measured at 12 months were compared with those originally predicted. Results: Complete Abbreviated Injury Scale score information was available for 617 individuals, of whom 587 (95%) could be assigned at least one FCI score (range, 1-17). Agreement between the largest predicted FCI and observed FCI score was poor (kappa = 0.05; 95% confidence interval, 0.00-0.10) and explained only 1% of the variability in observed FCI. Using an encompassing model that included all FCI assignments, agreement remained poor (kappa = 0.05; 95% confidence interval, -0.02-0.12), and the model explained only 9% of the variability in observed FCI. Conclusion: The predicted functional capacity poorly agrees with actual functional outcomes. Further research should consider including other (noninjury) explanatory factors in predicting FCI at 12 months.

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O presente trabalho investigar como os professores das séries iniciais do ensino fundamental entendem o ato de pesquisar a própria prática; e cotejar as visões dos professores sobre pesquisa com o referencial teórico específico. Para dar concretude a esses objetivos utilizamos a abordagem qualitativa. Temos como público alvo desse estudo cinco professores de uma escola pública situada no Município de Salvador Bahia. Inicialmente, descrevemos brevemente o contexto histórico da pesquisa, seus fundamentos, bem como os do professor pesquisador, elencando definições de pesquisa, com falas e posicionamentos de teóricos que discutem o tema. Consta também de explanação sobre as categorias e subcategorias elegidas no decorrer das atividades de pesquisa realizadas em campo. Tais categorias emergem nas observações e entrevistas realizadas com gestores e professores da instituição pesquisada e por serem recorrentes nas falas desses sujeitos. Obtemos, a partir das categorias construídas no processo da pesquisa, como principais resultados: a compreensão dos sujeitos pesquisados sobre a pesquisa da própria prática é limitada e equivocada; o universo considerado é totalmente avesso ao processo de pesquisa da prática, pois os professores estão imersos num emaranhado de sérias problemáticas explicitadas em nossos registros de observação. Concluímos afirmando que, apesar dos professores pesquisados não realizarem a pesquisa da prática, a nosso ver, essa é uma ação possível e que se concretiza também através da formação contínua e em serviço.(AU)

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On behalf of my coauthors, Dr Michael Larkin and Professor Paul Flowers, and I would like to thank Dr Pierre Pluye for his letter in response to our article.1 Dr Pluye supported our argument that a broader evidence base is needed in evidence-based healthcare. He provided the readers of this journal with important additional information which updates them on the progress in the area of mixed studies reviews and further detail about the Mixed Methods Appraisal Tool (MMAT).2 Since writing our …

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Acompanha: A diferença está no saber agir: conheça!: educação inclusiva: dos documentos legais à realidade escolar

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The Board of Medicine, through efficient and effective organization, will license, monitor, discipline, educate, and when appropriate, rehabilitate physicians to assure their fitness and competence in the practice of medicine. The Board protects and enhances the public’s health, safety and welfare by establishing and maintaining standards of excellence used in regulating the practices of medicine, surgery, and acupuncture and ensuring quality health care for Iowans.

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The Board of Medicine, through efficient and effective organization, will license, monitor, discipline, educate, and when appropriate, rehabilitate physicians to assure their fitness and competence in the practice of medicine. The Board protects and enhances the public’s health, safety and welfare by establishing and maintaining standards of excellence used in regulating the practices of medicine, surgery, and acupuncture and ensuring quality health care for Iowans.

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The Board of Medicine, through efficient and effective organization, will license, monitor, discipline, educate, and when appropriate, rehabilitate physicians to assure their fitness and competence in the practice of medicine. The Board protects and enhances the public’s health, safety and welfare by establishing and maintaining standards of excellence used in regulating the practices of medicine, surgery, and acupuncture and ensuring quality health care for Iowans.

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Background: TCF7L2 polymorphisms have been consistently associated with type 2 diabetes mellitus in different populations and type 2 diabetes mellitus is a major risk factor for cardiovascular disease, especially coronary artery disease. This study aimed to evaluate the association between TCF7L2 polymorphism rs7903146 and coronary artery disease in diabetic and non-diabetic subjects. Methods and Results: two populations were studied in order to assess severity of coronary artery disease and cardiovascular events incidence. Eight-hundred and eighty nine subjects who were referred for cardiac catheterization for coronary artery disease diagnosis were cross-sectionally evaluated for coronary lesions (atherosclerotic burden) and 559 subjects from the MASS-II Trial were prospectively followed-up for 5 years and assessed for major cardiovascular events incidence. As expected, rs7903146 T allele was associated with diabetes. Although diabetic patients had a higher prevalence of coronary lesions, no association between TCF7L2 genotype and coronary lesions was found in this subgroup. However, non-diabetic individuals carrying the T allele were associated with a significantly higher frequency of coronary lesions than non-diabetic non-carriers of the risk allele (adjusted OR = 2.32 95% CI 1.27-4.24, p = 0.006). Moreover, presence of multi-vessel coronary artery disease was also associated with the CT or TT genotypes in non-diabetics. Similarly, from the prospective sample analysis, non-diabetics carrying the CT/TT genotypes had significantly more composite cardiovascular end-points events than CC carriers (p = 0.049), mainly due to an increased incidence of death (p = 0.004). Conclusions: rs7903146 T allele is associated with diabetes and, in non-diabetic individuals, with a higher prevalence and severity of coronary artery disease and cardiovascular events. name of registry site (see list below), registration number, trial registration URL in brackets.

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Objective: To provide a detailed description of the nasopharyngeal intubation (NPI) technique and photographs, which should be helpful for those who may need to perform it for treating the airway obstruction in Robin sequence. Design: To describe and illustrate the NPI technique and the necessary considerations for its application. Setting: Hospital de Reabilitacao de Anomalias Craniofacial of University of Sao Paulo, Brazil. Result: The NPI procedure involves the use of a whitish, Portex, number 3.0 or 3.5, silicone tube, introduced 8 cm deep into the infant`s nostril and fixed with Micropore tape. The tube is to be removed at least twice a day for proper hygiene (with running water, detergent, and swabs) and should be changed every 7 days. This procedure is taught to the children`s parents or caretakers by the nurse during hospitalization. Conclusion: The technique is so simple that it can be performed by the parents themselves, allowing continuation of the treatment at home.

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Background:. Although the role of the lung alveolar macrophage (AM) as a mediator of acute lung injury (ALI) after lung ischemia/reperfusion (I/R) has been suggested by animal experiments, it has not been determined whether AMs mediate ALI after intestinal I/R. The objective of this study was to determine the effect of AM elimination on ALI after intestinal I/R in rats. Mwthods: Male Wistar rats (n = 90) were randomly divided into three groups: the clodronate-liposomes (CLOD-LIP) group received intratracheal treatment with CLOD-LIP; the liposomes (LIP) group received intratracheal treatment with LIP; and the nontreated (UNTREAT) group received no treatment. Twenty-four hours later each group was randomly divided into three subgroups: the intestinal I/R subgroup was subjected to 45-minute intestinal ischemia and 2-hour reperfusion; the laparotomy (LAP) subgroup was subjected to LAP and sham procedures; the control (CTR) subgroup received no treatment. At the end of reperfusion, ALI was quantitated in all the animals by the Evans blue dye (EBD) method. Results: ALI values are expressed as EBD lung leakage (mu g EBD/g dry lung weight). EBD lung leakage values in the CLOD-LIP group were 32.59 +/- 12.74 for I/R, 27.74 +/- 7.99 for LAP, and 33.52 +/- 10.17 for CTR. In the LIP group, lung leakage values were 58.02 +/- 18.04 for I/R, 31.90 +/- 8.72 for LAP, and 27.17 +/- 11.48 for CTR. In the UNTREAT group, lung leakage values were 55.60 +/- 10.96 for I/R, 35.99 +/- 6.89 for LAP, and 30.83 +/- 8.41 for CTR. Within each group, LAP values did not differ from CTR values. However, in the LIP and UNTREAT groups, values for both the LAP and CTR subgroups were lower than values for the I/R subgroup (p < 0.001). The CLOD-LIP I/R subgroup value was less (p < 0.001) than the I/R subgroup values in the LIP and UNTREAT groups. These results indicated that I/R provokes ALI that can be prevented by CLOD-LIP treatment, and further suggested that AMs are essential for ALI occurrence induced by intestinal I/R in rats.