908 resultados para Kelsey, Francis W. (Francis Willey), b.1858
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Polska zrobiła w obszarze reform w latach 2009-2011 pierwsze kroki w kierunku, na który patrzymy bardzo życzliwie. Jednak pierwsze kroki wymagają kroków kolejnych – bardziej stanowczych i bardziej skoordynowanych, opartych na fundamencie zmian już wprowadzanych w życie – którym będzie towarzyszyć przekonująca wizja przyszłości, a także adekwatne do skali przewidywanych zmian publiczne nakłady finansowe. Wizja jest niezbędna. Wspólnota akademicka, a przede wszystkim jej najmłodsze pokolenie, musi wiedzieć, na jakich podstawach ma budować swoją akademicką przyszłość i czy jest w stanie się w niej odnaleźć. Warto jasno powiedzieć, że z czasem pojawi się bardziej zróżnicowany system instytucji szkolnictwa wyższego, o różnych możliwościach i różnych zadaniach w różnych miejscach, realizujących różne misje i oferujących różne możliwości awansowe i finansowe. Warto powiedzieć, że niezbędne – ale i możliwe – będą pionowe migracje w ramach różnicującego się systemu w zależności od indywidualnych zdolności, umiejętności, pracowitości, a przede wszystkim mierzalnych osiągnięć naukowych. Należy także przypomnieć, że profesja akademicka nie daje równych szans wszystkim, ponieważ talenty naukowe w ramach wspólnoty akademickiej nie rozkładają się równo, ale z pewnością daje duże szanse najzdolniejszym; że w najlepszych ośrodkach naukowy wymiar kariery akademickiej, tak jak w świecie zachodnim, jest najważniejszy, a wszystkie pozostałe są tylko jego tłem; że z czasem wzorce pracy akademickiej i wzorce akademickich zarobków – w wybranych miejscach i dla wybranych grup badaczy – będą przypominać wzorce znane z najlepszych systemów zachodnich; i wreszcie, że w tych wybranych miejscach (zwanych uniwersytetami badawczymi czy flagowymi) uprawianie nauki nie będzie jednostkowym, częściowo niezrozumiałym i częściowo jedynie tolerowanym, hobby.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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We search for the production of a heavy W ' gauge boson that decays to third generation quarks in 0: 9 fb(-1) of p (p) over bar collisions at root s = 1: 96 TeV, collected with the D0 detector at the Fermilab Tevatron collider. We find no significant excess in the final-state invariant mass distribution and set upper limits on the production cross section times branching fraction. For a left-handed W ' boson with SM couplings, we set a lower mass limit of 731 GeV. For right-handed W ' bosons, we set lower mass limits of 739 GeV if the W ' boson decays to both leptons and quarks and 768 GeV if the W ' boson decays only to quarks. We also set limits on the coupling of the W ' boson to fermions as a function of its mass.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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To investigate the potential role of vitamin or mineral supplementation on the risk of head and neck cancer (HNC), we analyzed individual-level pooled data from 12 casecontrol studies (7,002 HNC cases and 8,383 controls) participating in the International Head and Neck Cancer Epidemiology consortium. There were a total of 2,028 oral cavity cancer, 2,465 pharyngeal cancer, 874 unspecified oral/pharynx cancer, 1,329 laryngeal cancer and 306 overlapping HNC cases. Odds ratios (OR) and 95% confidence intervals (CIs) for self reported ever use of any vitamins, multivitamins, vitamin A, vitamin C, vitamin E, and calcium, beta-carotene, iron, selenium and zinc supplements were assessed. We further examined frequency, duration and cumulative exposure of each vitamin or mineral when possible and stratified by smoking and drinking status. All ORs were adjusted for age, sex, race/ethnicity, study center, education level, pack-years of smoking, frequency of alcohol drinking and fruit/vegetable intake. A decreased risk of HNC was observed with ever use of vitamin C (OR = 0.76, 95% CI = 0.590.96) and with ever use of calcium supplement (OR = 0.64, 95% CI = 0.420.97). The inverse association with HNC risk was also observed for 10 or more years of vitamin C use (OR = 0.72, 95% CI = 0.540.97) and more than 365 tablets of cumulative calcium intake (OR = 0.36, 95% CI = 0.160.83), but linear trends were not observed for the frequency or duration of any supplement intake. We did not observe any strong associations between vitamin or mineral supplement intake and the risk of HNC.
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Ephemeral polar glaciations during the middle-to-late Eocene (48-34 Ma) have been proposed based on far-field ice volume proxy records and near-field glacigenic sediments, although the scale, timing, and duration of these events are poorly constrained. Here we confirm the existence of a transient cool event within a new high-resolution benthic foraminiferal d18O record at Ocean Drilling Program (ODP) Site 738 (Kerguelen Plateau; Southern Ocean). This event, named the Priabonian oxygen isotope maximum (PrOM) Event, lasted ~140 kyr and is tentatively placed within magnetochron C17n.1n (~37.3 Ma) based on the correlation to ODP Site 689 (Maud Rise, Southern Ocean). A contemporaneous change in the provenance of sediments delivered to the Kerguelen Plateau occurs at the study site, determined from the <63 µm fraction of decarbonated and reductively leached sediment samples. Changes in the mixture of bottom waters, based on fossil fish tooth epsilon-Nd, were less pronounced and slower relative to the benthic d18O and terrigenous epsilon-Nd changes. Terrigenous sediment epsilon-Nd values rapidly shifted to less radiogenic signatures at the onset of the PrOM Event, indicating an abrupt change in provenance favoring ancient sources such as the Paleoproterozoic East Antarctic craton. Bottom water epsilon-Nd reached a minimum value during the PrOM Event, although the shift begins much earlier than the terrigenous epsilon-Nd excursion. The origin of the abrupt change in terrigenous sediment provenance is compatible with a change in Antarctic terrigenous sediment flux and/or source as opposed to a reorganization of ocean currents. A change in terrigenous flux and/or source of Antarctic sediments during the oxygen isotope maximum suggests a combination of cooling and ice growth in East Antarctica during the early late Eocene.
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The prochlorophytes are oxygenic prokaryotes differing from other cyanobacteria by the presence of a light-harvesting system containing both chlorophylls (Chls) a and b and by the absence of phycobilins. We demonstrate here that the Chl a/b binding proteins from all three known prochlorophyte genera are closely related to IsiA, a cyanobacterial Chl a-binding protein induced by iron starvation, and to CP43, a constitutively expressed Chl a antenna protein of photosystem II. The prochlorophyte Chl a/b protein (pcb) genes do not belong to the extended gene family encoding eukaryotic Chl a/b and Chl a/c light-harvesting proteins. Although higher plants and prochlorophytes share common pigment complements, their light-harvesting systems have evolved independently.
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Cytokines are important regulators of hematopoesis. Mutations in gamma c, which is a subunit shared by the receptors for interleukin (IL) 2, IL-4, and IL-7, have been causally associated with human X chromosome-linked severe combined immunodeficiency disease. This finding indicates a mandatory role for cytokine receptor signaling at one or more stages of lymphocyte development. To evaluate the cellular level at which gamma c is critical for lymphopoiesis, the effect of monoclonal antibodies to gamma c on the capacity of syngeneic bone marrow cells to reconstitute the hematopoietic compartment of lethally irradiated recipient mice was examined. We show that monoclonal antibody to gamma c blocked lymphocyte development at or before the appearance of pro-B cells and prior to or at the seeding of the thymus by precursor cells while erythromyeloid cell development was normal. These results suggest that one level of lymphocyte development that requires gamma c is a point in hematopoietic cell differentiation near the divergence of lymphopoiesis and erythromyelopoesis.
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Evangelus Pacificus [pseud.] is identified as Rev. Hubbard Winslow in Franklin B. Dexter's Biographical sketches of the graduates of Yale College, v. 5, New Haven, 1911, p. 721, and in William Cushing's Initials and pseudonyms, v. 2, Waltham, Mass., 1963, p. 303.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.