Sdo1p, the yeast orthologue of Shwachman-Bodian-Diamond syndrome protein, binds RNA and interacts with nuclear rRNA-processing factors

The Shwachman-Bodian-Diamond syndrome protein (SBDS) is a member of a highly conserved protein family of not well understood function, with putative orthologues found in different organisms ranging from Archaea, yeast and plants to vertebrate animals. The yeast orthologue of SBDS, Sdo1p, has been previously identified in association with the 60S ribosomal subunit and is proposed to participate in ribosomal recycling. Here we show that Sdo1p interacts with nucleolar rRNA processing factors and ribosomal proteins, indicating that it might bind the pre-60S complex and remain associated with it during processing and transport to the cytoplasm. Corroborating the protein interaction data, Sdo1p localizes to the nucleus and cytoplasm and co-immunoprecipitates precursors of 60S and 40S subunits, as well as the mature rRNAs. Sdo1p binds RNA directly, suggesting that it may associate with the ribosomal subunits also through RNA interaction. Copyright (C) 2009 John Wiley & Sons, Ltd.

Vägen till jämställdhet - Kvinnor i styrelserum eller män i förskolan? : En kritisk analys av den svenska jämställdhetsdiskursen

Equality between the sexes has been discussed in Sweden for more than 50 years. In the 60´s and during the 70´s the discourse that dominated the debate was based on the assumption that both men and women needed to liberate themselves from their traditional gender roles. In this approach information and education was perceived as the key to equality. During the 80´s however, power and subordination became the main focal point of concern within this debate, and focus upon changing the patriarchal power structures dominating society were perceived as the principal key for establishing equality between the sexes. Today, the latter discourse still dominates both the scientific and the political perspective upon equality. By examining the debate on equality from two different fields of occupation this paper tries to analyse the fact that the Swedish equality discourse looks very different on male - versus female domination. Although the proportion of male teachers in Swedish preschools is about 3 % and the amount of women serving as public company directors is about 20 %, the current discourse views male dominance within the business sector as problematic, whilst, the dominance of women in the preschool childcare sector as less problematic. In respect of the theory supported by Bourdieu (1999), Hirdman (1990 & 2003) and Foucault (1998 & 2002) this paper advocates that the discourse is biased and simplified and that a perspective that only focuses on areas of male domination sets the wrong priorities. With regards to equality ideals prevalent throughout Norway this paper concludes that the Swedish equality discourse needs a broader and more open approach to assure that Swedish institutions promote equality between men and women in the best possible way.

A new relationship between planning and democracy? Urban activism in Melbourne 1965-1975

This paper is a reflective overview of urban social protest in the years 1965-1975 and its influence on post-war planning, especially on models of public participation in planning, and conceptions of effective local democracy. Drawing extensively on a major study of urban activism in Melbourne, Australia, the paper discusses the political and organisational strategies used by activists in Melbourne’s inner city areas to resist the large-scale planning/urban renewal projects especially of the Victorian state government. The paper focuses on Melbourne’s inner city Residents’ Action Groups and examines their motivations, strategies and rationales, placing them within an international context of urban protest movements demanding local democracy and consultation. The paper concludes that the Melbourne urban protest movements of the late 60s and early 70s deserve recognition for their contribution to inclusive, consultative processes in planning decision-making. This is done within a context of questioning contemporary academic discussion around the interpretative concept of gentrification, widely and indiscriminately applied to this and later periods of urban change.

Editorial

When The Who sang about teenage angst in the 60s, their rock anthem ‘Talking about my Generation’ captured the divide between youth and beyond. Today, another divide – the digital divide – speaks to the issues of access, capital, and input that follow digital technologies. Like the earlier ‘me generation’, the new millennium D(igital) generation remains enigmatic, its members variously praised for their technological wizardry, criticised for their self-absorption, and pathologised for their unsociability. The D generation does not comprise youth alone, but the young are more exposed than others to the influence of new media and digital technologies. And like previous youth generations, they are often viewed as degenerate. A cybernetic degeneration symbolising society’s fears and cultural anxieties concerning the dehumanising prospects of technology appears most vividly in arguments about youth (Green & Bigum’s ‘aliens in the classroom’ [1993] is an apt description in this respect). Such negative rhetoric presents a dystopic view that tempers the more utopian, but equally reductionist visions of new technologies.

Modeling response rates in surveys of female sexual difficulty and dysfunction

INTRODUCTION: Studies that address sensitive topics, such as female sexual difficulty and dysfunction, often achieve poor response rates that can bias  results. Factors that affect response rates to studies in this area are not well characterized.
AIM: To model the response rate in studies investigating the prevalence of female sexual difficulty and dysfunction.
METHODS: Databases were searched for English-language, prevalence studies using the search terms: sexual difficulties/dysfunction, woman/women/female, prevalence, and cross-sectional. Studies that did not report response rates or were clinic-based were excluded. A multiple linear regression model was constructed.
MAIN OUTCOME MEASURES: Published response rates.
RESULTS: A total of 1,380 publications were identified, and 54 of these met our inclusion criteria. Our model explained 58% of the variance in response rates of studies investigating the prevalence of difficulty with desire, arousal, orgasm, or sexual pain (R(2) = 0.581, P = 0.027). This model was based on study design variables, study year, location, and the reported prevalence of each type of sexual difficulty. More recent studies (beta = -1.05, P = 0.037) and studies that only included women over 50 years of age (beta = -31.11, P = 0.007) had lower response rates. The use of face-to-face interviews was associated with a higher response rate (beta = 20.51, P = 0.036). Studies that did not include questions regarding desire difficulties achieved higher response rates than those that did include questions on desire difficulty (beta = 23.70, P = 0.034).
CONCLUSION: Response rates in prevalence studies addressing female sexual difficulty and dysfunction are frequently low and have decreased by an average of just over 1% per anum since the late 60s. Participation may improve by conducting interviews in person. Studies that investigate a broad range of ages may be less representative of older women, due to a poorer response in older age groups. Lower response rates in studies that investigate desire difficulty suggest that sexual desire is a particularly sensitive topic.

The origins of competency-based training

This article attempts to trace the origins of competency-based training (CBT), the theory of vocational education that underpins the National Training Framework in Australia. A distinction is made between societal and theoretical origins. This paper argues that CBT has its societal origins in the United States of America during the 1950s, 60s and 70s. Public debate and government initiatives centred on the widely held view that there was a problem with the quality of education in the United States. One of the responses to this crisis was the Performance-Based Teacher Education movement which synthesised the theory of education that became CBT.The theoretical origins of CBT derive principally from behaviourism and systems theory - two broad theoretical orientations that influenced educational debate in the United States during the fomative period of CBT. Most of the component parts of CBT were contributed by specialists with a background in one or both of these theoretical orientations.

The rise and fall of urban squatter settlements in Santiago de Chile

The thesis examines the forces at work that resulted in the proliferation in the 1950s-60s, and then the subsequent decline, in the number of urban squatter settelements in Santiago, Chile. A feature of the work is the fieldwork investigation on the material conditions within the squatter settlements households.

Migrancy, modernity and cultural sustainability

Australian Home Beautiful’s October 1960 Edition was devoted to the modernisation of the Victorian and Edwardian-era houses of Australian cities’ inner suburbs. One of the articles inside was entitled ‘Terrace Houses are Common Problem’, in which the magazine’s architectural consultant Leonard A. Bullen suggested; “With houses of this type, the multiplicity of embellishments that appear in almost every possible place is irritating to eyes that have become accustomed to the cleaner and less ornamented lines of modern houses” and “The first necessity is to get rid of the superfluous decoration and emphasise horizontal features.” (Bullen 1960, 31). The post-World War Two period was a time when Australia’s traditional imagining of itself was confronted by both popular modernity and a diversity of new migrant cultures and ways of thinking. In a contemporary environment that theoretically celebrates diversity and creates audiences for increasingly multiplying expressions of culture and history, perhaps it is time that 1950s and ‘60s alterations to old houses were re-imagined as intrinsic elements in Australia’s cultural landscape. This supposition will be discussed in relation to the United Nations’ 2002 Kanazawa Resolutions’ definition of the relationship between culture and sustainability as ‘dialogical coexistence’ (Nadarajah and Yamamoto 2007).

2 or 3 things I remember or should have known about him

Optic Antics celebrates the work of Film Artist Ken Jacobs’ substantial and ongoing materialist practice, straddling more than 50 years, complicit in the 60s explosion of experimental film and now witnessing and commenting on the digital onslaught. This practice includes 16mm films that are recognized as foundation works for an experimental artist based cinema, celebrated and ongoing film performances and a renewed digital practice that re-animates historic 3-D images in flicker form.

Alt.film.au(2) : Blogging at the margins in Australian retrospective 2012

In 1972 Albie Thoms wrote: ‘In Australia it has been impossible to elicit much sympathetic appraisal from critics who seem distressed by the relation of personal film to amateur movies. Even those proselytizing for the New cinema have underrated the personal film as a worthy antidote to the market assumptions of Hollywood.’ (Thoms 1978, p. 146) The question now is, of course, is anything different in 2012? The answer is of course yes and no. Although the politics remains frustratingly familiar the digital has progressed further to the point that where in the 60s every one picked up a guitar, now we pick up a video camera. A postscript relates those films in the program not available for inclusion in the original 90s rant- (i.e. they did not exist) I have further annotated this re-play of old wounds and victories with commentary on some of the films in the screening program.

Estudando a MPB: reflexões sobre a MPB, nova MPB e o que o público entende por isso

Este trabalho pretende discutir a evolução do uso da sigla MPB (Música Popular Brasileira), desde sua popularização, nos anos 60, até os dias de hoje, dando ênfase para sua ramificação recente conhecida como “Nova MPB”. Também se buscou compreender como se dá a recepção por parte do público brasileiro, procurando contrastar as informações obtidas nas pesquisas bibliográficas com a opinião de ouvintes de MPB reunidos através de um fórum da Internet.

Crédito PRONAF: conquista, afirmação e reconhecimento: o processo de formulação de uma política pública

Brazil is a huge country full of peculiar significant issues for those who want to make academic contributions for public policy making and implementation. Therefore, this work aims to contribute to the public policy making debate from the family farmers perspective. Starting with historical issues about Brazilian rural policy, this text highlights the National Program for Familiar Agriculture (PRONAF) credit policy and several relevant elements for the public administration on this specific field such as the Sistema Nacional de Crédito Rural (60¿s), the sector crisis on the 80¿s and the implementation of the PRONAF itself. The theoretical reference is based on several works related to policy making, especially under authors as Lindblom and Kingdon, based on the model build by Barzelay and Velarde which focus on the public policy processes. For the conclusion, some nuances are mentioned as developing needs such as policy appropriation, social actor movements and policy rebuilding itself

Alternativas ao Crédito Rural Tradicional

The subject of the current work was to analyze the subject of the adequacy of Brazilian's agricultural activity financing model, as an alternative for the traditional agriculture credit. The main basis for this research is the evidence that the official resources for new loans, wherein it is analyzed a period within 30 years, had their highest peak in the final 70's decade and beginning of the80¿s had experimented a consistent trajectory of decline, returning to the initial levels of the final decades of the 60¿s. In parallel with the situation above, it is evidenced the increase of the Brazilian agriculture production by the official data, mainly grain plowing, followed by diverse problems like high levels of default in and continuously debt roll over, indicating depauperation from the traditional model which was institutionalized in 1965, under the Law n. 4829. A survey of official data regarding those loans, their default and field research with banks that deal with agriculture loans, from a broad Bibliographical research, ,was made in order to verify their managing strategy and willingness to use new financing mechanisms. The main proposed alternatives were: a) Cédula de Produto Rural (Rural Product Bill) b) Cédula de Produto Rural, financial modality c) Bolsa de Mercadorias e de Futuro¿s proposal d) Agricultural Receivable on Security e) Model based on Local Credit Agencies The best instrument for leveling resources were the first four alternatives, analyzing the advantages and disadvantages of each proposal. The creation of a system based on local branches for credit had not shown to be viable as for the difficulties for implementation and functioning. The work also points out a need to review the segmentation concerning rural clients. The traditional format for segmentation distinguishes 2 groups of producers: commercial agriculture and familiar agriculture. A third group is in eminence, which is the survival agriculture, with needs and distinct characteristics, indicating that the requirements for their needs must not have to be made by credit forms, but as aid programs, education and social welfare.

Como se faz um tijucano? Reflexões sobre consumo, identidade e masculinidade em um bairro carioca

The love of cariocas for the city of Rio de Janeiro is widely known. As well as the cariocas, there is another social group, called tijucanos, which the love for the neighborhood is peculiar. The Tijuca zone, known by its tradition and development during the 60¿s, due to his local identity ¿ tijucana, definitely deserves prominence in the ¿wonderful city¿. The people of Tijuca can be known as a ¿personality¿ in Rio, and their habits of consumption seldom exceed the area¿s limits. Enclosure of histories and special characteristics, how to be a tijucano, an adjective that people of Tijuca are proud of, is one of the focus of this present study. To be an unconditional tijucano, who loves to walk around in the neighborhood, in the square, enjoy their lives in famous bars, ended up as a peculiarity in the carioca scenario, together with the people of Ipanema, Barra and many others, that together make Rio de Janeiro a unique city. In spite of the increasing visibility, there are few studies trying to understand the way heterosexual men interact with the world of consumer goods. In view of the great interest and in the contemporary world, the meaning of consumption has increased. The object of the present study is to try to understand how the people from Tijuca use the world of consumer goods to ¿become a man¿, i.e., to construct their male heterosexual identity. This analysis is crucial to investigate the construction of masculine gender identity of the people from Tijuca. The study was based on data gathered through deep interviews with nine men from Tijuca during the month of January 2007. The results have shown that the tijucanos interact with the neighborhood services and locals during the process of construction of gender and local identity. It was possible to notice that there are four differents stages, by means of, people use the world of consumer goods to identify themselves as men from Tijuca. Therefore, it is possible to conclude that it occurs the consumption of specific products and places in strategy to: define masculinity and local identity (when young person), move aside, assimilation, acceptation and reinforcement of that identity.

Desenvolvimento econômico e mercado de trabalho urbano no nordeste brasileiro

A história recente do Nordeste caracteriza-se por uma primeira fase de isolamento e outra de articulação. Nessa segunda fase, o dinamismo que se instala a partir da década de sessenta provocou profundas transformações na economia da região. Essas transformações implicaram em elevadas taxas de expansão do produto regional, alterações na estrutura produtiva através da adoção de novos processos de trabalho que implicou de um lado, na redução da demanda por trabalho e de outro, na sua expansão. Registrou-se, também, mudanças bastante significativas nos gêneros industriais reduzindo a participação na produção das indústrias de bens de consumo não-duráveis e aumentando de modo importante a participação das indústrias de bens intermediários voltadas para o mercado nacional e internacional, o que contribui para aumentar a dependência do Nordeste em relação as regiões mais ricas. As mudanças iniciadas no setor industrial se propagam para os setores primários, secundários e terciários. No setor agrícola, as transformações dificultaram a sobrevivência do trabalhador, ampliaram as relações capitalistas no setor manifestas na maior proletarização da mão-de-obra rural; estimularam as emigrações para. as cidades e elevaram consideravelmente a participação da população ocupada em atividades predominantemente urbanas. No setor terciário, as mudanças provocaram o incremento do subemprego, grande diferenciação nos 11 níveis de produtividade e rendimentos, gerando um quadro de aprofundamento da heterogeneidadeda estrutura produtiva e do mercado de trabalho. Adicionalmente, houve uma excessiva urbanização, aumento da concentração da renda, incremento do grau de informalidade, crescimento do número de empregados clandestinos e maior participação dos menores e adultos no mercado de trabalho. Tudo isso, ocorreu,associado ao quadro de dinamismo das atividades produtivas, sem paralelo na história recente das regiões atrasadas do pais. A análise dos dados também mostrou que o nível do desemprego aberto, é relativamente baixo tanto para os homens como para as mulheres. Isto ocorre porque na expansão ou na retração econômica as flutuações no nível de ocupação são acampanhadas por modificações da taxa de participação da PIA no mercado de trabalho. Portanto, a recente infonnalidade, fonnalidade e submersão da mão-de-obra no Nordeste estão associadas a um contexto de crescimento da economia e, por conseguinte, resultam do estilo ou padrão de acumulação de capital que, mesmo se realizando com altas taxas de expansão, não repercute positivamente no mercado de trabalho, nos tennos requeridos pela oferta de mão-de-obra. Assim, o aparecimento de um excedente relativo de população é resultado do padrão de acumulação da capital da economia regional, que está associado ao modo como o Nordeste se inseriu no contexto nacional e, nesse sentido, é o padrão de industrialização o principal fator responsável por parte importante do insucesso da economia local em absorver produtivamente a população que se apresenta no mercado de trabalho urbano