鸡血液中乙酰胆碱酯酶的提取研究

[目的]为了研究硫酸铵盐析法在乙酰胆碱酯酶分离纯化中的效果,从而利用乙酰胆碱酯酶的活性变化反映农药的污染情况。[方法]采用硫酸铵盐析和等电点区分的方法从鸡血中提取乙酰胆碱酯酶,并探讨其适宜的pH值范围。[结果]结果表明:pH值4.5左右大量的杂蛋白能被除去,可获得较高乙酰胆碱酯酶得率;采用饱和度为50%~60%的硫酸铵盐析效果较好,据此得出较佳的提取工艺。[结论]该研究结果为后续鸡血AChE的提取、分离、纯化等工作提供了相应的参考,同时为利用乙酰胆碱酯酶指示环境受有机磷和氨基甲酸酯类农药污染的后续研究和应

Low-rank optimization on the cone of positive semidefinite matrices

We propose an algorithm for solving optimization problems defined on a subset of the cone of symmetric positive semidefinite matrices. This algorithm relies on the factorization X = Y Y T , where the number of columns of Y fixes an upper bound on the rank of the positive semidefinite matrix X. It is thus very effective for solving problems that have a low-rank solution. The factorization X = Y Y T leads to a reformulation of the original problem as an optimization on a particular quotient manifold. The present paper discusses the geometry of that manifold and derives a second-order optimization method with guaranteed quadratic convergence. It furthermore provides some conditions on the rank of the factorization to ensure equivalence with the original problem. In contrast to existing methods, the proposed algorithm converges monotonically to the sought solution. Its numerical efficiency is evaluated on two applications: the maximal cut of a graph and the problem of sparse principal component analysis. © 2010 Society for Industrial and Applied Mathematics.

Low-rank optimization with trace norm penalty

The paper addresses the problem of low-rank trace norm minimization. We propose an algorithm that alternates between fixed-rank optimization and rank-one updates. The fixed-rank optimization is characterized by an efficient factorization that makes the trace norm differentiable in the search space and the computation of duality gap numerically tractable. The search space is nonlinear but is equipped with a Riemannian structure that leads to efficient computations. We present a second-order trust-region algorithm with a guaranteed quadratic rate of convergence. Overall, the proposed optimization scheme converges superlinearly to the global solution while maintaining complexity that is linear in the number of rows and columns of the matrix. To compute a set of solutions efficiently for a grid of regularization parameters we propose a predictor-corrector approach that outperforms the naive warm-restart approach on the fixed-rank quotient manifold. The performance of the proposed algorithm is illustrated on problems of low-rank matrix completion and multivariate linear regression. © 2013 Society for Industrial and Applied Mathematics.

Gaussian process volatility model

The prediction of time-changing variances is an important task in the modeling of financial data. Standard econometric models are often limited as they assume rigid functional relationships for the evolution of the variance. Moreover, functional parameters are usually learned by maximum likelihood, which can lead to over-fitting. To address these problems we introduce GP-Vol, a novel non-parametric model for time-changing variances based on Gaussian Processes. This new model can capture highly flexible functional relationships for the variances. Furthermore, we introduce a new online algorithm for fast inference in GP-Vol. This method is much faster than current offline inference procedures and it avoids overfitting problems by following a fully Bayesian approach. Experiments with financial data show that GP-Vol performs significantly better than current standard alternatives.

Low threshold current density 1.5 mu m strained-MQW laser by n-type modulation-doping

1.5 mu m. n-type modulation-doping InGaAsP/InGaAsP strained multiple quantum wells grown by low pressure metalorganic chemistry vapor decomposition technology is reported for the first time in the world. N-type modulation-doped lasers exhibit much lower threshold current densities than conventional lasers with undoped barrier layers. The lowest threshold current density we obtained was 1052.5 A/cm(2) for 1000 mu m long lasers with seven quantum wells. The estimated threshold current density for an infinite cavity length was 94.72A/cm(2)/well, reduced by 23.3% compared with undoped barrier lasers. The n-type modulation doping effects on the lasing characteristics in 1.5 mu m devices have been demonstrated.

个性化领域知识支持的用户主导需求获取方法

应用软件的需求获取与应用领域的特征密切相关,用户的参与日益受到重视,然而用户对系统的认识通常模糊且不完整,且对于多用户系统,需要拥有局部需求的多用户进行协同,才能得到完整、一致的需求.提出一种用户主导的需求获取方法,根据用户特征及其上下文环境,为用户进行需求定义提供个性化的领域知识支持,包括领域需求资产推荐和对多用户协同需求获取的建议.应用实例说明了该方法的可行性,且对于提高用户参与程度、改进领域知识重用效果,从而最终提高需求获取的质量具有积极意义.

Influence of 5A-Type Zeolite Powder on Tetrahydrofuran Hydrate Formation and Dissociation Process

Visual observations of tetrahydrofuran (THF) hydrate formation and dissociation processes with 5A-type zeolite powder were made at normal atmospheric conditions and below zero temperature by microscope. Results indicate that 5A-type zeolite powder can promote THF hydrate growth. At the same time, in the presence of 5A-type zeolite, agglomerated crystals and vein-like crystals of THF hydrate were also formed. SA-type zeolite powder increases the crystallization temperature and decreases the dissociation temperature. The particle size distribution of 5A-type zeolite powder influences THF hydrate formation and its dissociation characteristics significantly.

6H-SiC高压肖特基势垒二极管

在可商业获得的N型6H-SiC晶片上，通过化学气相淀积，进行同质外延生长，在此结构材料上，通过热蒸发，制作Ni/6H-SiC肖特基势垒二极管。测量并分析了肖特基二极管的电学特性，结果表明，肖特基二极管具有较好的整流特性

~(17)B的晕结构特征

实验利用束流衰减法测量了43.7AMeV丰中子核17B与C靶反应的总截面σR=(1724±93)mb.用零程Glauber计算,假定17B具有核芯15B和两个价中子结构,输入GG和GO密度分布,计算的激发函数曲线与该实验数据很好符合,输入描述稳定核双参数Fermi密度分布,不能得到与实验数据符合的结果,表明17B是核芯15B+2n的假定是合理的.并且中子密度分布表现较大空间扩展-晕结构特征.

Speed of the internal pellet target in CSRm

Pellet target is one of the main candidate targets in CSRm (cooler storage ring’s main ring) for hadron physics studies. Pellet speed is an important physical parameter for the target. Larger pellet speed could shorten the interacting time interval between the pellet and the cyclotron beam, and thus results in a small temperature variation for the pellet. This could make the pellet facility work in a stable con-dition. A fluid dynamic simulation was carried out for the pellet speed, and it was found that the maxi-mum speed for the target pellet may be restricted to about 100 m/s even if all working parameters were set to their optimal values.