Building a Social Education curriculum based on Professional Competences : the experience of University of Girona

This article describes the process of adapting Social Education studies to the European Higher Education Area undertaken by a team of the teaching staff at the University of Girona (Spain). The aim of the experience is to build a curriculum based on thecompetencies recognized as such by professionals in the field of social education in our region. The article specifies the development of the various phases, each involving the active participation of professionals and teaching staff from the universities. To conclude, main characteristics of the curriculum are highlighted

A chromatographic method for the production of a human immunoglobulin G solution for intravenous use

Immunoglobulin G (IgG) of excellent quality for intravenous use was obtained from the cryosupernatant of human plasma by a chromatographic method based on a mixture of ion-exchange, DEAE-Sepharose FF and arginine Sepharose 4B affinity chromatography and a final purification step by Sephacryl S-300 HR gel filtration. The yield of 10 experimental batches produced was 3.5 g IgG per liter of plasma. A solvent/detergent combination of 1% Tri (n-butyl) phosphate and 1% Triton X-100 was used to inactivate lipid-coated viruses. Analysis of the final product (5% liquid IgG) based on the mean for 10 batches showed 94% monomers, 5.5% dimers and 0.5% polymers and aggregates. Anticomplementary activity was 0.3 CH50/mg IgG and prekallikrein activator levels were less than 5 IU/ml. Stability at 37ºC for 30 days in the liquid state was satisfactory. IgG was stored in flasks (2.5 g/flask) at 4 to 8ºC. All the characteristics of the product were consistent with the requirements of the 1997 Pharmacopée Européenne.

Purification of human albumin by the combination of the method of Cohn with liquid chromatography

Large volumes of plasma can be fractionated by the method of Cohn at low cost. However, liquid chromatography is superior in terms of the quality of the product obtained. In order to combine the advantages of each method, we developed an integrated method for the production of human albumin and immunoglobulin G (IgG). The cryoprecipitate was first removed from plasma for the production of factor VIII and the supernatant of the cryoprecipitate was fractionated by the method of Cohn. The first precipitate, containing fractions (F)-I + II + III, was used for the production of IgG by the chromatographic method (see Tanaka K et al. (1998) Brazilian Journal of Medical and Biological Research, 31: 1375-1381). The supernatant of F-I + II + III was submitted to a second precipitation and F-IV was obtained and discarded. Albumin was obtained from the supernatant of the precipitate F-IV by liquid chromatography, ion-exchange on DEAE-Sepharose FF, filtration through Sephacryl S-200 HR and introduction of heat treatment for fatty acid precipitation. Viral inactivation was performed by pasteurization at 60ºC for 10 h. The albumin product obtained by the proposed procedure was more than 99% pure for the 15 lots of albumin produced, with a mean yield of 25.0 ± 0.5 g/l plasma, containing 99.0 to 99.3% monomer, 0.7 to 1.0% dimers, and no polymers. Prekallikrein activator levels were <=5 IU/ml. This product satisfies the requirements of the 1997 Pharmacopée Européenne.

妄占辯Wang zhan bian.Discussion contre les sorts.

Dirigée contre Yang Guang xian et les devins, par le P. Verbiest (1669). Gravé de nouveau à Canton, au Da yuan tang.A la table, 17sections ; manquent les sections 3 à 17 ; toutefois le volume, paraît complet. — Cordier, Imprimerie Sino-européenne, 358.

Chinois 5168-5169

Contient : I西醫略論Xi yi lüe lun.Traité abrégé de médecine européenne ; II婦嬰新說Fu ying xin shuo.Traité de médecine relatif aux femmes et aux enfants ; III內科新說Nei ke xin shuo.Nouveau traité de médecine interne ; IV全體新論Quan ti xin lun.Anatomie et physiologie de l'homme et des animaux

Chinois 7470-7472

Contient : I-V ; VI-XIV ; XV-XIX ; XX-XXXVI ; XXXVII ; XXXVIII馬耳可傳福音書 ; XXXIX聖路加傳福音之書Sheng lu jia chuan fu yin zhi shu ; XL若翰傳福音之書Ruo han chuan fu yin zhi shu ; XLI使徒行傳Shi tu xing zhuan ; XLII使徒保羅書Shi tu bao luo shu ; XLIII者米士卽牙可百之公書Zhe mi shi ji ya ke bai zhi gong shu ; XLIV使徒彼多羅之公書Shi tu bi duo luo zhi gong shu ; XLV使徒若翰之書Shi tu ruo han zhi shu ; XLVI使徒如大之公書Shi tu ru da zhi gong shu ; XLVII使徒若翰顯示之書Shi tu ruo han xian shi zhi shu

Chinois 7470-7472

Contient : I-V ; VI-XIV ; XV-XIX ; XX-XXXVI ; XXXVII ; XXXVIII馬耳可傳福音書 ; XXXIX聖路加傳福音之書Sheng lu jia chuan fu yin zhi shu ; XL若翰傳福音之書Ruo han chuan fu yin zhi shu ; XLI使徒行傳Shi tu xing zhuan ; XLII使徒保羅書Shi tu bao luo shu ; XLIII者米士卽牙可百之公書Zhe mi shi ji ya ke bai zhi gong shu ; XLIV使徒彼多羅之公書Shi tu bi duo luo zhi gong shu ; XLV使徒若翰之書Shi tu ruo han zhi shu ; XLVI使徒如大之公書Shi tu ru da zhi gong shu ; XLVII使徒若翰顯示之書Shi tu ruo han xian shi zhi shu