1000 resultados para parasitic network
Resumo:
Supply chain tracking information is one of the main levers for achieving operational efficiency. RFID technology and the EPC Network can deliver serial-level product information that was never before available. However, these technologies still fail to meet the managers' visibility requirements in full, since they provide information about product location at specific time instances only. This paper proposes a model that uses the data provided by the EPC Network to deliver enhanced tracking information to the final user. Following a Bayesian approach, the model produces realistic ongoing estimates about the current and future location of products across a supply network, taking into account the characteristics of the product behavior and the configuration of the data collection points. These estimates can then be used to optimize operational decisions that depend on product availability at different locations. The enhancement of tracking information quality is highlighted through an example. © 2009 IFAC.
Resumo:
Berea clava, new species, is described based on the specimens recovered from the gill filaments of a flounder, Pseudorhombus arsius (H.-B.), collected in Kuwait Bay of Arabian (Persian) Gulf. This is the second species of Berea.
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A new species Norileca borealis belonging to the family Cymothoidae is described in detail and illustrated. The new species is distinguished from the other members of the genus by the details of maxilla 2, maxilliped, pleotelson and pereopod 1.
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Three species of caligid copepods (Siphonostomatoida) belonging to genus Hermilius Heller, 1865 were recovered from the giant marine catfish, Arius thalassinus Ruppell, taken from the Persian Gulf. They are H. pyriventris Heller, 1865; H. longicaudus n. sp.; and H. longicornis Bassett-Smith, 1898. H helleri Pillai, 1963 is proposed to be relegated to the synonym of H pyriventris. A key to the eight species of Hermilius is provided.
Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition
Resumo:
Functional glycine receptors (GlyRs) are enriched in the hippocampus, but their role in hippocampal function remains unclear. Since the concentration of ambient glycine is determined by the presence of powerful glycine transporter (GlyT), we blocked the r
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Background: Giardia are a group of widespread intestinal protozoan parasites in a number of vertebrates. Much evidence from G. lamblia indicated they might be the most primitive extant eukaryotes. When and how such a group of the earliest branching unicellular eukaryotes developed the ability to successfully parasitize the latest branching higher eukaryotes (vertebrates) is an intriguing question. Gene duplication has long been thought to be the most common mechanism in the production of primary resources for the origin of evolutionary novelties. In order to parse the evolutionary trajectory of Giardia parasitic lifestyle, here we carried out a genome-wide analysis about gene duplication patterns in G. lamblia. Results: Although genomic comparison showed that in G. lamblia the contents of many fundamental biologic pathways are simplified and the whole genome is very compact, in our study 40% of its genes were identified as duplicated genes. Evolutionary distance analyses of these duplicated genes indicated two rounds of large scale duplication events had occurred in G. lamblia genome. Functional annotation of them further showed that the majority of recent duplicated genes are VSPs (Variant-specific Surface Proteins), which are essential for the successful parasitic life of Giardia in hosts. Based on evolutionary comparison with their hosts, it was found that the rapid expansion of VSPs in G. lamblia is consistent with the evolutionary radiation of placental mammals. Conclusions: Based on the genome-wide analysis of duplicated genes in G. lamblia, we found that gene duplication was essential for the origin and evolution of Giardia parasitic lifestyle. The recent expansion of VSPs uniquely occurring in G. lamblia is consistent with the increment of its hosts. Therefore we proposed a hypothesis that the increment of Giradia hosts might be the driving force for the rapid expansion of VSPs.
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Sequence analysis of the mitochondrial genome has become a routine method in the study of mitochondrial diseases. Quite often, the sequencing efforts in the search of pathogenic or disease-associated mutations are affected by technical and interpretive pr
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Iteration is unavoidable in the design process and should be incorporated when planning and managing projects in order to minimize surprises and reduce schedule distortions. However, planning and managing iteration is challenging because the relationships between its causes and effects are complex. Most approaches which use mathematical models to analyze the impact of iteration on the design process focus on a relatively small number of its causes and effects. Therefore, insights derived from these analytical models may not be robust under a broader consideration of potential influencing factors. In this article, we synthesize an explanatory framework which describes the network of causes and effects of iteration identified from the literature, and introduce an analytic approach which combines a task network modeling approach with System Dynamics simulation. Our approach models the network of causes and effects of iteration alongside the process architecture which is required to analyze the impact of iteration on design process performance. We show how this allows managers to assess the impact of changes to process architecture and to management levers which influence iterative behavior, accounting for the fact that these changes can occur simultaneously and can accumulate in non-linear ways. We also discuss how the insights resulting from this analysis can be visualized for easier consumption by project participants not familiar with simulation methods. Copyright © 2010 by ASME.