997 resultados para Porfiria cutânea tardia
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O objetivo principal deste artigo é levantar algumasexplicações possíveis para o sucesso editorial do segmento daautoajuda a partir das últimas décadas do século passado. Paratanto, quatro eixos explicativos são desenvolvidos: 1) vivemos umperíodo de reflexividade que abre espaço para as receitas e osmodelos da autoajuda; 2) outras formas de racionalidade, numacontraposição à visão de Max Weber, abrem espaço para o saberprofessado pelos gurus da autoajuda; 3) a autoajuda tem umafunção terapêutica fundamental numa época que vive os dilemasda modernidade tardia; 4) o modelo de competência que imperano imaginário organizacional contemporâneo abre espaço paraos ensinamentos da autoajuda. Rastreando essas explicaçõesprocurar-se-á mostrar de que forma as especificidades do nossotempo constituem terreno fértil para a autoajuda.
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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB
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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB
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Dermatosparaxis in animals is an autosomal recessive disorder of the connective-tissue clinically characterized by skin fragility and hiperextensibility. The disease in White Dorper sheep is caused by mutation (c.421G>T) in the ADAM metalloproteinase with thrombospondin type 1 motif, 2 (ADAMTS2) gene. This study describes the dermatological, histological and the molecular findings of the dermatosparaxis in White Dorper sheep from a herd located in the center-west of São Paulo State. The herd consisted of one ram, four ewe and their lambs. In this herd two lambs had clinical signs consistent with dermatosparaxis. Histopathological evaluation of the affected skin of these two animals also revealed consistent findings with dermatosparaxis, characterized by dysplasia of the collagen, which were arranged in small and fragmented collagen bundles and with foci of degeneration of collagen. Prominent cutaneous appendages and severe hemorrhagic focus in dermis region associated with mild neutrophilic infiltrate in the deep dermis. PCR using DNA blood and specific primers to amplify the mutation region c.421G>T was optimized in order to perform molecular diagnosis of the disease. The direct sequencing of the PCR products proved that the two clinically affected animals had the mutation responsible for dermatosparaxis, previously described for this breed and allowed the definitive diagnosis of the disease. This is the first report of the dermatosparaxis in White Dorper sheep in Brazil and the methodology used to confirm the diagnosis could be used in future studies to assess the prevalence of this mutation in Brazil, allowing the adoption of measures to prevent the spread of this mutation in the Brazilian White Dorper herd.
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The efficiency of the topical use of a commercial product constituted by a herbal combination on the healing evolution of equine induced wounds was studied. A skin lesion in the shape of a square with 5cm sides was surgically produced on both sides of the buttocks of eight adult horses. One side was considered control and another one treated. Both control and treated sides were rinsed with water and neutral soap. Additionally, the wound on the treated side received the topical treatment with the herbal combination. Macroscopic and microscopic healing evolution of the wounds was evaluated and their areas were determined during the experimental period. There was statistical difference between wound areas. At the last evaluation, the average area of the control side was 0.70cm² and of the treated side was 1.23cm². The contraction of scar observed at 77 days was 97.57% for the control side and 95.59% for the treated side.
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The objective of this study was to identify clones of sugarcane with good stability and adaptability in the State of São Paulo, Brazil, and also identifying locations most representative for selection and experimentation. Ten clones and two commercial checks of medium-late maturation were evaluated in the first-ratoon of experiments harvested in August 2009, using bissegmented regression and AMMI (Additive Main Effects and Multiplicative Interaction Analysis) methods. The results of two methods were compared and they evidenced that the clones RB975201, RB975157, RB975932, RB975242 and RB975162 are the most promising, showing higher production when compared to the checks, higher stability observed in one or both statistical methods and broader or more specific adaptability. The environment Tarumã presented higher stability and capacity to discriminate genotypes, allowing an ordering more reliable as compared to the overall mean of the environments tested.
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Pós-graduação em Agronomia - FEIS
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Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB
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Pós-graduação em Ciências Sociais - FFC
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Pós-graduação em Agronomia (Agricultura) - FCA
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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In this paper we intend to understand the functioning of Freudian psychism concerning the constitution of the psychic subject in his relation with knowledge. In order to do that, we will analyze one of the most important writings by Freud: An Outline of Psycho-Analysis. This choice was made because we think that the author synthesizes his thought in that book, whose maturity makes possible for us to access a later elaboration of the functioning and the conceptions we intend to analyze: The regions of Psychic apparatus; The problem of the Psycho-Analysis approach: science and philosophy; and The psychic qualities of the subject.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)