995 resultados para Pena, Martins 1815-1848
Resumo:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Resumo:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Resumo:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Resumo:
Twenty eight species of Temnocerus Thunberg, 1815 are recognized from Central America (Mexico to Panama) with eight previously described species and 20 new species as follows: T. abdominalis (Voss), T. chiapensis n. sp., T. chiriquensis (Sharp), T. confertus (Sharp), T. cyaneus n. sp., T. ellus n. sp., T. giganteus n. sp., T. guatemalenus (Sharp), T. guerrerensis n. sp., T. herediensis n. sp., T. mexicanus n. sp., T. michoacensis n. sp., T. minutus n. sp., T. niger n. sp., T. oaxacensis n. sp., T. obrieni, n. sp., T. oculatus (Sharp), T. potosi n. sp., T. pseudaeratus n. sp., T. pueblensis n. sp., T. pusillus (Sharp), T. regularis (Sharp), T. rostralis n. sp., T. rugosus n. sp., T. salvensis n. sp., T. tamaulipensis n. sp., T. thesaurus (Sharp) and T. yucatensis n. sp. Rhynchites debilis Sharp is placed in synonymy with Temnocerus guatemalenus (Sharp) and Pselaphorhynchites lindae Hamilton is placed in synonymy with Temnocerus regularis (Sharp). A key to species based on external characters and male genitalia is provided as well as digital images, aedeagus drawings, and map distributions.
Resumo:
The aim of the present study was to evaluate the behavioral patterns associated with autism and the prevalence of these behaviors in males and females, to verify whether our model of lipopolysaccharide (LPS) administration represents an experimental model of autism. For this, we prenatally exposed Wistar rats to LPS (100 mu g/kg, intraperitoneally, on gestational day 9.5), which mimics infection by gram-negative bacteria. Furthermore, because the exact mechanisms by which autism develops are still unknown, we investigated the neurological mechanisms that might underlie the behavioral alterations that were observed. Because we previously had demonstrated that prenatal LPS decreases striatal dopamine (DA) and metabolite levels, the striatal dopaminergic system (tyrosine hydroxylase [TH] and DA receptors D1a and D2) and glial cells (astrocytes and microglia) were analyzed by using immunohistochemistry, immunoblotting, and real-time PCR. Our results show that prenatal LPS exposure impaired communication (ultrasonic vocalizations) in male pups and learning and memory (T-maze spontaneous alternation) in male adults, as well as inducing repetitive/restricted behavior, but did not change social interactions in either infancy (play behavior) or adulthood in females. Moreover, although the expression of DA receptors was unchanged, the experimental animals exhibited reduced striatal TH levels, indicating that reduced DA synthesis impaired the striatal dopaminergic system. The expression of glial cell markers was not increased, which suggests that prenatal LPS did not induce permanent neuroinflammation in the striatum. Together with our previous finding of social impairments in males, the present findings demonstrate that prenatal LPS induced autism-like effects and also a hypoactivation of the dopaminergic system. (c) 2012 Wiley Periodicals, Inc.
Resumo:
Toxoplasma gondii is a protozoan parasite that infects humans and other warm-blooded animals; it uses feral and domestic cats as the definitive hosts. Neospora caninum is a protozoan parasite of animals whose life cycle is very similar to T. gondii but uses canids as definitive hosts. Small rodents play an important role in the life cycle of T. gondii, and a few findings indicated that they may be natural intermediate hosts for N. caninum. The present study was aimed at identifying infections by T. gondii and N. caninum in urban rodents. Infections by T. gondii were quantified using isolation of the parasite by bioassay in mice; molecular methods were also used for both parasites. Overall, 217 rodents were captured. Brain and heart tissues of all rodents were bioassayed in mice for the detection of T. gondii infection. Brain and heart tissues of 121 rodents had the DNA extracted for molecular analysis. Toxoplasma gondii was isolated by bioassay from a single rodent. From the 121 rodents tested for the presence of T. gondii DNA, 2 animals were positive. In contrast, DNA of N. caninum was not detected in any of the samples. In conclusion, the surveys of N. caninum and T. gondii infection in Rattus rattus, Rattus norvegicus, and Mus musculus captured in urban areas of Sao Paulo reveal a striking low frequency of occurrence of these infections.
Resumo:
Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.
Resumo:
Programa de doctorado: Acuicultura: producción controlada de animales acuáticos.
Resumo:
This dissertation aims at enhancing the cultural and linguistic skills in Portuguese of the author of this work, as it is a third language. This activity is carried out starting from the analysis and research of topics mentioned in a number of texts within a particular literary work, “Portugal Vale A Pena”. In this work, many Portuguese personalities express their vision on their country and state why Portugal matters. Since these texts have many cultural references, it can be assumed that such work of analysis and research can lead to better linguistic skills as well as a greater knowledge of the Portuguese culture. All of the chosen texts were originally written by journalists. This choice originates from the important service these professionals provide to the public as well as from the special role their work has played in my interpreting studies over the last couple of years. Chapter 1 explains why I chose this dissertation and who are the target users of these texts. Chapter 2 focuses on the role of journalists. A brief history of modern journalism is presented and its functions are analysed. This chapter also includes a section that examines which values make an event newsworthy. Attention is then paid to the evolution of Portuguese journalism, from Salazar's dictatorship until today. Teaching of journalism in Portuguese academia is also presented. Then, a selection of Portuguese-language media is offered. Chapter 3 focuses on some aspects of Portugal, with particular attention to its history. Finally, Chapter 4 presents a selection of texts from the original book. This part provides a biography of the authors, a translation with a comment and a presentation of some of the topics from the texts. To conclude, a glossary with words and expressions from the original text is included and their translations into Italian, Spanish and English are provided.