998 resultados para Casos difíciles


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The squamous cell carcinoma is the most common malignancy in the oral cavity, representing over 90% of cancers in this region. This study aimed to conduct an epidemiological study of oral squamous carcinoma cases diagnosed by the Department of Pathology, Department of Pathology and Clinical Propaedeutics in the Dentistry Faculty of Araçatuba - UNESP, in the period between 1995 and 2005. 185 cases were studied, it was observed that the oral floor and tongue were the sites most affected, with predominance in males, white race and aged between 41 and 60 years, noting that the majority of patients were smokers. Knowledge of these data is important for the dental surgeon to act preventively, contributing to early diagnosis of cancer.

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Paracoccidioidomycosis is a systemic mycosis which requires prolonged treatment. It is highest prevalence in Latin America, with different endemic areas in Brazil. In this study the aim was to characterize clients suffering from mucocutaneous paracoccidioidomycosis by analysis of histopathological examinations of 61 adult patients diagnosed with mucocutaneous paracoccidioidomycosis treated at the Dental School of Araçatuba, from January 1989 to December 2004. It was observed that the disease occurred in 91.81% (56) men and 8.19% (5) women, more prevalent (78.68%) in whites, aged 40 to 59 years (62.9%) and the profession linked to agriculture in 17 patients (27.86%). All patients had oral manifestations, in multiple sites, but it was most prevalent in the oral mucosa (31.42%) and alveolar ridge (17.14%). The dentist as an integral member of the health services, must know the clinical manifestations of paracoccidioidomycosis to achieve early diagnosis and thereby to improve the quality of life of patients.

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Usually diagnosed in routine radiographs, the simple bone cyst occurs infrequently. Etiology is unknown and differential diagnosis has to be made with dentigerous cyst, keratocystic odontogenic tumor, adenomatoid odontogenic tumor, ameloblastoma and central giant cell granuloma. Treatment is surgical, by perforating the cortical bone. In most cases an empty cavity, without any capsule or epithelial covering, is encountered, but it may have a liquid content. Perforation of the mandibular cortical bone elicits a response that results in bone repair of the empty cavity. This article reviews the subject and presents two cases of this entity and discusses the possible factors that could interfere in healing course.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Contractors Odebrecht, Camargo Correa and Andrade Gutierrez play an important role in Brazil's economy stressed by the number of jobs they add, capital accumulation and diversification through the acquisition of state firms and assets. Abroad, they rank among the top companies in the industry. Is there a behavioral standard among these firms? How did they grow? Why did they diversify? What triggers them to internationalization and what are the strategies they adopt in the foreign markets? The attempt to shed light on these questions resulted in the observation of patterns inside Brazilian market as they grew and diversified, but such a pattern could not be detected in the internationalization process

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The real role of renal transplantation in hepatic fi brosis progression caused by hepatitis C virus is still unpredictable. Histological evaluation of the liver is the best form to estimate fi brosis evolution, although semiquantitative analysis carries important limitations. Objective: To apply a morphometric quantitative assay on hepatic fi brosis progression in renal recipients with hepatits C. Methods: Thirty patients were initially evaluated, but only seven were included. They underwent the fi rst biopsy near the transplantation date and the second biopsy at least 4 years later. The immunosuppressant therapy adopted in all cases was azatioprine and micofenolate. Fibrosis progression rate (FPR) was calculated before and after the surgery date in each patient according to Metavir score and morphometric analysis. Results: The FPR calculated by Metavir score showed no statistical difference between pre- and post-transplantation (p=0.9). The FPR calculated by the morphometric analysis was 0.58 ± 0.78 before transplantation and 3.0 ± 3.3 after the surgery, with statistical signi- fi cance between these values (p=0.0026). Conclusion: In the sample assessed, the progression of hepatic fi brosis was documented and quantifi ed only by the morphometric analysis, which is as a promising approach to histological evaluation of these patients.

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Introdução: A ocorrência de verruga genital (condiloma acuminados) em crianças é uma condição relativamente rara, porém está associada a significativo estresse em familiares e cuidadores devido a possível associação com abuso sexual. Objetivos: Verificar o padrão clínico e demográfico dos casos de condiloma acuminado genital em crianças atendidas em serviço público de dermatologia.Tipo de estudo e local: Estudo retrospectivo descritivo conduzido em ambulatório público de dermatologia pediátrica.Métodos: Estudo retrospectivo descritivo de casos de condiloma acuminado genital em menores de 12 anos de idade atendidas entre 2003 e 2012 em ambulatório público de dermatologia pediátrica. Foram excluídos casos que não apresentavam confirmação histológica, ou não realizaram acompanhamento terapêutico na instituição.Resultados: Foram incluídos 10 casos. Houve predomínio do sexo feminino e a idade ao diagnóstico variou de 2 a 11 anos. As áreas mais acometidas, em ordem decrescente, foram a perianal, a glútea e os grandes lábios. Ocorreram três relatos de abuso sexual. Após acompanhamento de 1 a 16 meses com média de 5,8 meses, 6/10 pacientes apresentavam-se sem lesões.Conclusões: O condiloma acuminado genital foi mais frequente em meninas, esteve associado ao histórico de abuso sexual em 30% dos casos e apresentou boa resposta terapêutica de um modo geral.

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Three newborn Mini-Horses and one Brazilian Pony horses were presented to the Veterinary Hospital with phenotypic appearance of dwarfism. They had relatively larger head conformation, occlusive dental defect and musculoskeletal changes such as abnormal short limbs and deformation on the third metatarsal bone. The radiographic examination showed abnormal growth plates on femoral condyle and proximal thirds metatarsal bones. Due to the high possibility of future complications and quality of life loss, the animals were euthanized. We emphasize the importance of recognition of phenotypic changes related to dwarfism in horses, enabling the phenotypic diagnosis can direct crossings for nontransmission of this abnormality as genetic inheritance.

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Hyperkalemia is a common electrolyte imbalance in cats with obstructive feline lower urinary tract disease (FLUTD). The effects of serum potassium elevation in heart rhythm are serious and potentially lethal. The clinical manifestations reflect changes in the excitability of the cell membrane. Increased potassium levels lead to a reduction of the resting membrane potential of heart muscle cells, making them less excitable and resulting in cardiac arrhythmias. The sinoventricular rhythm with atrial arrest is among the types of arrhythmias caused by hyperkalemia. The purpose of this report was to highlight the importance of electrocardiographic monitoring for the early detection of potentially lethal arrhythmias in cats with obstructive FLUTD. We hereby describe the occurrence of three cases treated at the Small Animal Clinic of FMVZ/Unesp, Botucatu Campus.

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Necrotizing fasciitis is a rare dermatopathy that promotes subcutaneous tissue damage, associated to substantial morbidity and mortality if treatment is not initiated at the beginning of the condition. The objective of the present study is to report the occurrence of two cases of necrotizing fasciitis, one in a miniature female Pinscher and the other one in a female Poodle, both attended at the Veterinary Hospital of FMVZ/Unesp-Botucatu. The animals presented ulcerated, erythematous lesions with secretion and points of necrosis along fascial planes. Bacterial culture was positive for Streptococcus spp. The animals were treated with enrofloxacin, associated to topical cleaning of the lesions with saline solution and triclosan-based soap and rifampicin spray. Both animals presented total remission of lesions after approximately 15 days of treatment. The present report aims to alert veterinary clinicians to the severity of Streptococcus spp infections.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)