Silkworm silk cocoon structure-property relationship

A collection of images examining the microstructure of raw cocoons. The research investigates how the microstructure varies from one layer to another in the same cocoon and also from one cocoon variety to another. The research is being undertaken to study the structure and property relationships, specifically the antibacterial properties, photodegradability and mechanical strength of different cocoon components - fibre, sericin, and crystals. The aim is to understand the role of different cocoon components and their mechanism of protecting the pupa from extremes of climatic conditions, microorganisms, and other pathogens and predators. Scanning electron microscopy (SEM) and Energy Dispersive Spectroscopy (EDS) were used to analyse the structure of the cocoons, fibre, and sericin.

The raft-promoting property of virion-associated cholesterol, but not the presence of virion-associated brij 98 rafts, is a determinant of human immunodeficiency virus type 1 infectivity

Lipid rafts are enriched in cholesterol and sphingomyelin and are isolated on the basis of insolubility in detergents, such as Brij 98 and Triton X-100. Recent work by Holm et al. has shown that rafts insoluble in Brig 98 can be found in human immunodeficiency virus type 1 (HIV-1) virus-like particles, although it is not known whether raft-like structures are present in authentic HIV-1 and it is unclear whether a virion-associated raft-like structure is required for HIV replication. Independently, it was previously reported that virion-associated cholesterol is critical for HIV-1 infectivity, although the specific requirement of virion cholesterol in HIV-1 was not examined. In the present study, we have demonstrated that infectious wild-type HIV-1 contains Brij 98 rafts but only minimal amounts of Triton X-100 rafts. To directly assess the functional requirement of virion-associated rafts and various features of cholesterol on HIV-1 replication, we replaced virion cholesterol with exogenous cholesterol analogues that have demonstrated either raft-promoting or -inhibiting capacity in model membranes. We observed that variable concentrations of exogenous analogues are required to replace a defined amount of virion-associated cholesterol, showing that structurally diverse cholesterol analogues have various affinities toward HIV-1. We found that replacement of 50% of virion cholesterol with these exogenous cholesterol analogues did not eliminate the presence of Brij 98 rafts in HIV-1. However, the infectivity levels of the lipid-modified HIV-1s directly correlate with the raft-promoting capacities of these cholesterol analogues. Our data provide the first direct assessment of virion-associated Brij 98 rafts in retroviral replication and illustrate the importance of the raft-promoting property of virion-associated cholesterol in HIV-1 replication.

Optimization of gaussian fuzzy membership functions and evaluation of the monotonicity property of fuzzy inference systems

In this paper, two issues relating to modeling of a monotonicity-preserving Fuzzy Inference System (FIS) are examined. The first is on designing or tuning of Gaussian Membership Functions (MFs) for a monotonic FIS. Designing Gaussian MFs for an FIS is difficult because of its spreading and curvature characteristics. In this study, the sufficient conditions are exploited, and the procedure of designing Gaussian MFs is formulated as a constrained optimization problem. The second issue is on the testing procedure for a monotonic FIS. As such, a testing procedure for a monotonic FIS model is proposed. Applicability of the proposed approach is demonstrated with a real world industrial application, i.e., Failure Mode and Effect Analysis. The results obtained are analysis and discussed. The outcomes show that the proposed approach is useful in designing a monotonicity-preserving FIS model.

Novel approaches to process bamboo plants into fibres and their UV-blocking property

Currently viscose production methods are primarily used to process bamboo into commercial textile fibres. However, viscose methods use large quantities of chemicals and hence the process is not considered as environmentally friendly. The process also fails to retain bamboo’s inherent unique properties such as ultraviolet (UV) screening and antibacterial functions. Hence, it is necessary to design an effective and more eco-friendly manufacturing method that would also retain the unique properties of raw bamboo plant into the fibres. In this research, bamboo was processed using new methods involving thermo mechanical treatments such as ultra-sonication, shaker milling and boiling with continuous stirring. Sodium hydroxide, hydrogen peroxide, enzyme and water were used separately in this process and their effects on fibre processing were compared. The morphology and UV shielding ability were analysed before and after processing. It was demonstrated that bamboo can be processed into fibres using only water and ball milling without the aid of any hazardous chemicals. The combination of mild acid hydrolysis and ultrasonic treatment with hydrogen peroxide was effective in the fibre separation and provided better appearance of fibres.

Intellectual property rights in indigenous cultural heritage : basic concepts and continuing controversies

The developments at international level in the debate on what intellectual property (IP) lawyers refer to as traditional cultural expressions (TCEs) have to be seen in the context of the decolonisation movements after the Second World War. Post-war developments saw the formation of the United Nations (UN) and the emphasis on human rights in the UN Charter. With this emphasis came development programmes for indigenous peoples and the recognition of indigenous rights in the ILO Convention No. 107 of the 1957 Concerning the Protection and Intergration of Indigenous and Other Tribal and Semi-Tribal Populations in the Independant Countries. The decolonisation movements also initiated or renewed a parallel debate about the repatriation of items of cultural heritage. There was a remarkable shift in this discussion from 'cultural heritage of mankind' to cultural particularism and an emphasis on 'cultural property' ....

Direct versus search engine traffic : an innovative approach to demand analysis in the property market

Purpose – The application of “Google” econometrics (Geco) has evolved rapidly in recent years and can be applied in various fields of research. Based on accepted theories in existing economic literature, this paper seeks to contribute to the innovative use of research on Google search query data to provide a new innovative to property research.

Design/methodology/approach – In this study, existing data from Google Insights for Search (GI4S) is extended into a new potential source of consumer sentiment data based on visits to a commonly-used UK online real-estate agent platform (Rightmove.co.uk). In order to contribute to knowledge about the use of Geco's black box, namely the unknown sampling population and the specific search queries influencing the variables, the GI4S series are compared to direct web navigation.

Findings – The main finding from this study is that GI4S data produce immediate real-time results with a high level of reliability in explaining the future volume of transactions and house prices in comparison to the direct website data. Furthermore, the results reveal that the number of visits to Rightmove.co.uk is driven by GI4S data and vice versa, and indeed without a contemporaneous relationship.

Originality/value – This study contributes to the new emerging and innovative field of research involving search engine data. It also contributes to the knowledge base about the increasing use of online consumer data in economic research in property markets.

When is property inherently defeasible for the purposes of s 51(xxxi)?

This article traces the development of the jurisprudence surrounding compulsory acquisition of property with a particular focus on the application of s 51(xxxi) of the Australian Constitution to statutory property. The examination reveals a clearly articulated methodology developed by the High Court that is principled, transparent and logically consistent with the purpose of the provision. This is contrasted with two recent decisions of the High Court, ICM Agriculture Pty Ltd v Commonwealth and Phonographic Performance Company of Australia Ltd v Commonwealth which indicate a concerning development to move away from such methodology and introduce new factors for consideration. It is argued that such development threatens to undermine the principled and transparent application of s 51(xxxi) and may reintroduce unnecessary methodological uncertainty.