Rapid determination of 12 antibiotics and caffeine in sewage and bioreactor effluent by online column-switching liquid chromatography/tandem mass spectrometry

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A new family of zero-current-switching PWM converters and a novel HPF-ZCS-PWM boost rectifier

A new family of direct current (DC) to DC converters based on a zero current switching pulse width modulated (ZCS-PWM) soft commutation cell is presented. This ZCS-PWM cell is consists of two transistors, two diodes, two inductors and one capacitor; and provides zero voltage turn-on to the diodes, a zero-current turn-on and a zero-current zero-voltage turn-off to the transistors. In addition, a new commutation cell in a new ZCS-PWM boost rectifier is developed, obtaining a structure with power factor near the unity, high efficiency at wide load range and low total harmonic distortion in the input current.

Straight and angulated abutments in platform switching: influence of loading on bone stress by three-dimensional finite element analysis

PURPOSE: In view of reports in the literature on the benefits achieved with the use of platform switching, described as the use of an implant with a larger diameter than the abutment diameter, the goal being to prevent the (previously) normal bone loss down to the first thread that occurs around most implants, thus enhancing soft tissue aesthetics and stability and the need for implant inclination due to bone anatomy in some cases, the aim of this study was to evaluate bone stress distribution on peri-implant bone, by using three-dimensional finite element analysis to simulate the influence of implants with different abutment angulations (0 and 15 degrees) in platform switching. METHODS: Four mathematical models of an implant-supported central incisor were created with varying abutment angulations: straight abutment (S1 and S2) and angulated abutment at 15 degrees (A1 and A2), submitted to 2 loading conditions (100 N): S1 and A1-oblique loading (45 degrees) and S2 and A2-axial loading, parallel to the long axis of the implant. Maximum (σmax) and minimum (σmin) principal stress values were obtained for cortical and trabecular bone. RESULTS: Models S1 and A1 showed higher σmax in cortical and trabecular bone when compared with S2 and A2. The highest σmax values (in MPa) in the cortical bone were found in S1 (28.5), followed by A1 (25.7), S2 (11.6), and A2 (5.15). For the trabecular bone, the highest σmax values were found in S1 (7.53), followed by A1 (2.87), S2 (2.85), and A2 (1.47). CONCLUSIONS: Implants with straight abutments generated the highest stress values in bone. In addition, this effect was potentiated when the load was applied obliquely.

Implantes Platform Switching: longevidade e preservação óssea: revisão crítica da literatura

The concept of switching platform is the use of an implant by platform wider than the abutment. Recently, researches have shown that this type of dental implant design tends to offer a higher preservation of crestal bone when compared to the traditional pattern of bone loss. The present study aims to perform a critical review on the switching platform concept establishing possible advantages of the technique. A search was performed on Medline/Pubmed about the topic “dental implant” and “platform switching”, and after applying inclusion criteria 40 studies were selected. The literature on longevity present prospective studies that show less bone loss, studies in biomechanics exhibit better or similar stress distribution around the bone crest, however, is not yet defined the role of the biological width. Thus, studies of longevity, and randomized prospective studies are of a great relevance to be performed in order to confirm the benefits of this technique and to establish a protocol indication. It is possible, based on this literature review, to conclude that longitudinal and randomized studies show that the platform switching implants have longevity and less bone loss. Biomechanically, the technique is possible.

Aplicações das Cadeias de Markov para o Ensino Médio

Pós-graduação em Matemática em Rede Nacional - IBILCE

Switching-off in a minimal time a fitzhugh-nagumo system

This paper deals with a system that describes an electrical circuitcomposed by a linear system coupled to a nonlinear one involving a tunneldiode in a flush-and-fill circuit. One of the most comprehensive models for thiskind of circuits was introduced by R. Fitzhugh in 1961, when taking on carebiological tasks. The equation has in its phase plane only two periodic solutions,namely, the unstable singular point S0 and the stable cycle Γ. If the system isat rest on S0, the natural flow of orbits seeks to switch-on the process by going- as time goes by - toward its steady-state, Γ. By using suitable controls it ispossible to reverse such natural tendency going in a minimal time from Γ toS0, switching-off in this way the system. To achieve this goal it is mandatorya minimal enough strength on controls. These facts will be shown by means ofconsiderations on the null control sets in the process.

Técnicas de otimização em alinhamentos múltiplos de sequência via Cadeias de Markov

Pós-graduação em Ciência da Computação - IBILCE

Survivable Waveband Switching in WDM Mesh Networks under Dedicated Path-Protection

This paper considers the problem of dedicated path-protection in wavelength-division multiplexed (WDM) mesh networks with waveband switching functionality under shared risk link group (SRLG) constraints. Two dedicated path protection schemes are proposed, namely the PBABL scheme and the MPABWL scheme. The PBABL scheme protects each working waveband-path through a backup waveband-path. The MPABWL scheme protects each working waveband-path by either a backup waveband-path or multiple backup lightpaths. Heuristic algorithms adopting random optimization technique are proposed for both the schemes. The performance of the two protection schemes is studied and compared. Simulation results show that both the heuristics can obtain optimum solutions and the MPABWL scheme leads to less switching and transmission costs than the PBABL scheme.

Same-Destination-Intermediate Grouping vs. End-to-End Grouping for Waveband Switching in WDM Mesh Networks

We investigate waveband switching (WBS) with different grouping strategies in wavelength-division multiplexing (WDM) mesh networks. End-to-end waveband switching (ETEWBS) and same-destination-intermediate waveband switching (SD-IT-WBS) are analyzed and compared in terms of blocking probability and cost savings. First, an analytical model for ETEWBS is proposed to determine the network blocking probability in a mesh network. For SD-IT-WBS, a simple waveband switching algorithm is presented. An analytical model to determine the network blocking probability is proposed for SD-IT-WBS based on the algorithm. The analytical results are validated by comparing with simulation results. Both results match well and show that ETE-WBS slightly outperforms SD-IT-WBS in terms of blocking probability. On the other hand, simulation results show that SD-IT-WBS outperforms ETE-WBS in terms of cost savings.

A Novel Cost-Efficient On-Line Intermediate Waveband-Switching Scheme in WDM Mesh Networks

Waveband switching (WBS) is an important technique to save switching and transmission cost in wavelength -division multiplexed (WDM) optical networks. A cost-efficient WBS scheme would enable network carriers to increase the network throughput (revenue) while achieving significant cost savings. We identify the critical factors that determine the WBS network throughput and switching cost and propose a novel intermediate waveband switching (IT-WBS) algorithm, called the minimizing-weighted-cost (MWC) algorithm. The MWC algorithm defines a cost for each candidate route of a call. By selecting the route with the smallest weighted cost, MWC balances between minimizing the call blocking probability and minimizing the network switching cost. Our simulations show that MWC outperforms other wavelength/waveband switching algorithms and can enhance the network throughput at a reduced cost.

Discontinuous Waveband Switching in WDM Optical Networks

Routing techniques used in wavelength routed optical networks (WRN) do not give an efficient solution with Waveband routed optical networks (WBN) as the objective of routing in WRN is to reduce the blocking probability and that in WBN is to reduce the number of switching ports. Routing in WBN can be divided two parts, finding the route and grouping the wavelength assigned into that route with some existing wavelengths/wavebands. In this paper, we propose a heuristic for waveband routing, which uses a new grouping strategy called discontinuous waveband grouping to group the wavelengths into a waveband. The main objective of our algorithm is to decrease the total number of ports required and reduce the blocking probability of the network. The performance of the heuristic is analyzed using simulation on a WBN with non-uniform wavebands.

A Generic Autonomous Clustering-Based Heterogeneous Waveband Switching Architecture in WDM Networks

Heterogeneous waveband switching (HeteroWBS) in WDM networks reduces the network operational costs. We propose an autonomous clustering-based HeteroWBS architecture to support the design of efficient HeteroWBS algorithms under dynamic traffic requests in such a network.

A Graph Model for DynamicWaveband Switching in WDM Mesh Networks

We investigate the problem of waveband switching (WBS) in a wavelength-division multiplexing (WDM) mesh network with dynamic traffic requests. To solve the WBS problem in a homogeneous dynamic WBS network, where every node is a multi-granular optical cross-connect (MG-OXC), we construct an auxiliary graph. Based on the auxiliary graph, we develop two heuristic on-line WBS algorithms with different grouping policies, namely the wavelength-first WBS algorithm based on the auxiliary graph (WFAUG) and the waveband-first WBS algorithm based on the auxiliary graph (BFAUG). Our results show that the WFAUG algorithm outperforms the BFAUG algorithm.

Integrated Intermediate Waveband and Wavelength Switching for Optical WDM Mesh Networks

As wavelength-division multiplexing (WDM) evolves towards practical applications in optical transport networks, waveband switching (WBS) has been introduced to cut down the operational costs and to reduce the complexities and sizes of network components, e.g., optical cross-connects (OXCs). This paper considers the routing, wavelength assignment and waveband assignment (RWWBA) problem in a WDM network supporting mixed waveband and wavelength switching. First, the techniques supporting waveband switching are studied, where a node architecture enabling mixed waveband and wavelength switching is proposed. Second, to solve the RWWBA problem with reduced switching costs and improved network throughput, the cost savings and call blocking probabilities along intermediate waveband-routes are analyzed. Our analysis reveals some important insights about the cost savings and call blocking probability in relation to the fiber capacity, the candidate path, and the traffic load. Third, based on our analysis, an online integrated intermediate WBS algorithm (IIWBS) is proposed. IIWBS determines the waveband switching route for a call along its candidate path according to the node connectivity, the link utilization, and the path length information. In addition, the IIWBS algorithm is adaptive to real network applications under dynamic traffic requests. Finally, our simulation results show that IIWBS outperforms a previous intermediate WBS algorithm and RWA algorithms in terms of network throughput and cost efficiency.

Killer Whales and Marine Mammal Trends in The North Pacific—A Re-Examination of Evidence for Sequential Megafauna Collapse and the Prey-Switching Hypothesis

Springer et al. (2003) contend that sequential declines occurred in North Pacific populations of harbor and fur seals, Steller sea lions, and sea otters. They hypothesize that these were due to increased predation by killer whales, when industrial whaling’s removal of large whales as a supposed primary food source precipitated a prey switch. Using a regional approach, we reexamined whale catch data, killer whale predation observations, and the current biomass and trends of potential prey, and found little support for the prey-switching hypothesis. Large whale biomass in the Bering Sea did not decline as much as suggested by Springer et al., and much of the reduction occurred 50–100 yr ago, well before the declines of pinnipeds and sea otters began; thus, the need to switch prey starting in the 1970s is doubtful. With the sole exception that the sea otter decline followed the decline of pinnipeds, the reported declines were not in fact sequential. Given this, it is unlikely that a sequential megafaunal collapse from whales to sea otters occurred. The spatial and temporal patterns of pinniped and sea otter population trends are more complex than Springer et al. suggest, and are often inconsistent with their hypothesis. Populations remained stable or increased in many areas, despite extensive historical whaling and high killer whale abundance. Furthermore, observed killer whale predation has largely involved pinnipeds and small cetaceans; there is little evidence that large whales were ever a major prey item in high latitudes. Small cetaceans (ignored by Springer et al.) were likely abundant throughout the period. Overall, we suggest that the Springer et al. hypothesis represents a misleading and simplistic view of events and trophic relationships within this complex marine ecosystem.