Malaria entomological inoculation rates in gold mining areas of Southern Venezuela

A longitudinal study of malaria vectors aiming to describe the intensity of transmission was carried out in five villages of Southern Venezuela between January 1999-April 2000. The man-biting, sporozoite and entomological inoculation rates (EIR) were calculated based on 121 all-night collections of anophelines landing on humans, CDC light traps and ultra violet up-draft traps. A total of 6,027 female mosquitoes representing seven species were collected. The most abundant species were Anopheles marajoara Galvão & Damasceno (56.7%) and Anopheles darlingi Root (33%), which together accounted for 89.7% of the total anophelines collected. The mean biting rate for An. marajoara was 1.27 (SD + 0.81); it was 0.74 (SD + 0.91) for An. darlingand 0.11 (SD + 0.10) for Anopheles neomaculipalpus Curry and the overall biting rate was 2.29 (SD + 1.06). A total of 5,886 mosquitoes collected by all three methods were assayed by ELISA and 28 pools, equivalent to 28 mosquitoes, yielded positive results for Plasmodium spp. CS protein. An. neomaculipalpus had the highest sporozoite rate 0.84% (3/356), followed by An. darlingi 0.82% (16/1,948) and An. marajoara 0.27% (9/3,332). The overall sporozoite rate was 0.48% (28/5,886). The rates of infection by Plasmodium species in mosquitoes were 0.37% (22/5,886) for Plasmodium vivax(Grassi & Feletti) and 0.10% (6/5,886) for Plasmodium falciparum (Welch). The estimated overall EIR for An. darling was 2.21 infective bites/person/year, 1.25 for An. marajoara and 0.34 for An. neomaculipalpus. The overall EIR was four infective bites/person/year. The biting rate, the sporozoite rate and the EIR are too low to be indicators of the efficacy of control campaigns in this area.

Distribution of Lymnaeidae (Mollusca: Pulmonata), intermediate snail hosts of Fasciola hepatica in Venezuela

An extensive malacological survey was carried out between 2005-2009 in order to clarify the exact number of lymnaeid species which may be intermediate hosts of Fasciola hepatica in Venezuela. Four species were discovered during this survey, including two local species: Lymnaea cubensis and Lymnaea cousini and two exotic species: Lymnaea truncatula and Lymnaea columella. The most common local species was L. cubensis which was found at 16 out of the 298 sampling sites. This species has a large distribution area throughout the Northern part of Venezuela and was encountered from sea level to an altitude of 1,802 m in state of Trujillo. The second local species L. cousini was collected at only two sites of the Andean Region at altitudes of 3,550 m and 4,040 m, respectively. The European L. truncatula was found at 24 sites all located in the states of Mérida and Táchira at an altitude varying between 1,540-4,000 m. The respective distribution areas of L. cubensis and L. truncatula do not appear to overlap, but more detailed malacological surveys are needed. The fourth lymnaeid species, L. columella was collected in a canal from Mérida at an altitude of 1,929 m and in an irrigation canal from the state of Guárico, at an altitude of 63 m. The role of these four lymnaeid species in the transmission of fascioliasis in Venezuela is discussed.

Malaria seroprevalence in blood bank donors from endemic and non-endemic areas of Venezuela

In Venezuela, a total of 363,466 malaria cases were reported between 1999-2009. Several states are experiencing malaria epidemics, increasing the risk of vector and possibly transfusion transmission. We investigated the risk of transfusion transmission in blood banks from endemic and non-endemic areas of Venezuela by examining blood donations for evidence of malaria infection. For this, commercial kits were used to detect both malaria-specific antibodies (all species) and malaria antigen (Plasmodium falciparum only) in samples from Venezuelan blood donors (n = 762). All samples were further studied by microscopy and polymerase chain reaction (PCR). The antibody results showed that P. falciparum-infected patients had a lower sample/cut-off ratio than Plasmodium vivax-infected patients. Conversely, a higher ratio for antigen was observed among all P. falciparum-infected individuals. Sensitivity and specificity were higher for malarial antigens (100 and 99.8%) than for antibodies (82.2 and 97.4%). Antibody-positive donors were observed in Caracas, Ciudad Bolívar, Puerto Ayacucho and Cumaná, with prevalences of 1.02, 1.60, 3.23 and 3.63%, respectively. No PCR-positive samples were observed among the donors. However, our results show significant levels of seropositivity in blood donors, suggesting that more effective measures are required to ensure that transfusion transmission does not occur.

El programa de estancia temporal 2011 atiende a 3.124 menores del Sahara, Rusia y Europa del este acogidos por familias andaluzas

Boletín semanal para profesionales sanitarios de la Secretaría General de Salud Pública y Participación Social de la Consejería de Salud

Cuestiones de pintura y miniatura en Cerdeña: modelos, intercambios y relaciones internacionales en la segunda mitad del siglo XV

Durante el siglo XV Cerdeña desempeña, gracias a su posicionamiento geográfico en el centro del Mediterráneo, un papel muy importante en la red de comercio internacional. Este movimiento económico-cultural fomenta una extensa producción artística que está caracterizada por depender fuertemente de la presencia en la isla de talleres y artistas catalanes. Al día de hoy se conoce muy poco la presencia y las características de la pintura del gótico tardío en la Cerdeña. Las dificultades encontradas por los investigadores en la reconstrucción de la historia del arte sarda de esta época son numerosas y difíciles de solucionar. El problema depende de la falta de fuentes documentales (directas e indirectas), de la gran dispersión de muchísimas obras, de la inaccesibilidad de unas de las obras más interesantes; del desplazamiento casi total de las obras de su sitio original, y del total anonimato de la mayoría de los artistas. En estas condiciones la única solución para alcanzar nuevos elementos científicos es: integrar los conocimientos procedente de las fuentes documentales; ampliar la practica metodológica (multidisciplinariedad), conectar el tejido sardo (pintura, miniatura, grabados) con el ámbito internacional. El objetivo final es introducir la pintura sarda en un contexto más amplio, para poder descubrir el sistema de modelos y de relaciones artísticas, que la conectan con el mundo artístico mediterráneo. El trabajo de este primer año ha sido particularmente intenso y complicado por las dificultades encontradas en ponerse en un tema tan vasto como lo de la pintura y los modelos figurativos de la segunda mitad del siglo XV. Principales objetivos: averiguar toda la bibliografía conocida sobre el tema e intentar ampliar los estudios cada vez que se encontraban indicios sobre posibles autores y obras sardas; empezar el trabajo de catalogación de las obras pictóricas (conocidas o recien descubiertas.)

Serologic follow-up of IgG responses against recombinant mycobacterial proteins ML0405, ML2331 and LID-1 in a leprosy hyperendemic area in Venezuela

Leprosy is a slowly evolving disease that occurs mainly in adults. In this study, the Mamaría Village, state of Portuguesa was selected because it had one of the highest prevalence rates (13.25%) of leprosy cases in 1997. Between 1998-2004, 20.2% of the 89 cases registered in this village were less than 15 years old and 61.8% were males. Pau-cibacillary (PB) lesions were the predominant clinical forms identified, although also multibacillary (MB) forms were found. Additionally, 76% of the patients were bacteriologically negative. At the time of diagnosis, 75% of the patients presented with grade 0 disabilities, 23% with grade 1 and 2% with grade 2. Serum samples were collected from 18 PB and 15 MB patients, in addition to 14 family contacts, at the beginning and end of treatment. All the groups were re-evaluated during a three-year period (2008-2011). The proteins used for evaluation were ML0405, ML2331 and LID-1. These mycobacterial proteins were highly specific for Mycobacterium leprae and the IgG responses decreased in both MB and PB patients during multidrug treatment. Our results suggest that these antigens could be used as markers for successful treatment of non-reactional lepromatous patients.

Malaria entomological risk factors in relation to land cover in the Lower Caura River Basin, Venezuela

To explore the effects of deforestation and resulting differences in vegetation and land cover on entomological parameters, such as anopheline species composition, abundance, biting rate, parity and entomological inoculation rate (EIR), three villages were selected in the Lower Caura River Basin, state of Bolívar, Venezuela. All-night mosquito collections were conducted between March 2008-January 2009 using CDC light traps and Mosquito Magnet(r) Liberty Plus. Human landing catches were performed between 06:00 pm-10:00 pm, when anophelines were most active. Four types of vegetation were identified. The Annual Parasite Index was not correlated with the type of vegetation. The least abundantly forested village had the highest anopheline abundance, biting rate and species diversity. Anopheles darlingi and Anopheles nuneztovari were the most abundant species and were collected in all three villages. Both species showed unique biting cycles. The more abundantly forested village of El Palmar reported the highest EIR. The results confirmed previous observations that the impacts of deforestation and resulting changes in vegetation cover on malaria transmission are complex and vary locally.

La importància dels aspectes culturals en les relacions empresarials a la Xina : implicacions per a les empreses espanyoles

La diferència cultural existent entre Espanya i la Xina és gairebé abismal. No es tracta tan sols del llenguatge, sinó que la conducta social d'espanyols i xinesos segueixen camins ben diferents. Quan ens centrem en el món empresarial, observem que la cultura dels negocis també pateix aquestes diferències, les quals, si no se saben salvar poden desembocar en negociacions fallides. El que es pretén en aquest treball de recerca és oferir una primera visió global (encara que una mica superficialment) d'aquesta cultura dels negocis xinesa per tal de facilitar d'acostament d'aquests dos països en l'àmbit comercial.

La Experiencia populista y militarista en la Venezuela contemporánea

El presente artículo persigue dar cuenta del proceso político venezolano de la última década, donde registramos no sólo un deterioro pronunciado de los partidos políticos sino fundamentalmente de entramado democrático, y el establecimiento de un sistema político populista profundamente proclive a estructurase sobre el papel protagónico del componente militar, con rasgos o elementos democráticos, autoritarios e incluso totalitarios donde justamente quedan alterados parámetros básicos de la democracia como la división de los poderes públicos, la supremacía de la Constitución o el necesario establecimientos de pesos y contrapesos frente al presidencialismo desmedido que muestra Venezuela en la última década. La premisa que guía nuestra investigación es que registramos un deterioro del sistema democrático, la precariedad justamente del Estado de derecho y de la institucionalidad democrática (procesos, procedimientos y otros) explica un ejercicio de gobierno distorsionado y la permanencia de Chávez en el poder bajo un régimen menos representativo, más participativo, mesiánico, militarista y personalista.

Update on oral Chagas disease outbreaks in Venezuela: epidemiological, clinical and diagnostic approaches

Orally transmitted Chagas disease has become a matter of concern due to outbreaks reported in four Latin American countries. Although several mechanisms for orally transmitted Chagas disease transmission have been proposed, food and beverages contaminated with whole infected triatomines or their faeces, which contain metacyclic trypomastigotes of Trypanosoma cruzi, seems to be the primary vehicle. In 2007, the first recognised outbreak of orally transmitted Chagas disease occurred in Venezuela and largest recorded outbreak at that time. Since then, 10 outbreaks (four in Caracas) with 249 cases (73.5% children) and 4% mortality have occurred. The absence of contact with the vector and of traditional cutaneous and Romana’s signs, together with a florid spectrum of clinical manifestations during the acute phase, confuse the diagnosis of orally transmitted Chagas disease with other infectious diseases. The simultaneous detection of IgG and IgM by ELISA and the search for parasites in all individuals at risk have been valuable diagnostic tools for detecting acute cases. Follow-up studies regarding the microepidemics primarily affecting children has resulted in 70% infection persistence six years after anti-parasitic treatment. Panstrongylus geniculatushas been the incriminating vector in most cases. As a food-borne disease, this entity requires epidemiological, clinical, diagnostic and therapeutic approaches that differ from those approaches used for traditional direct or cutaneous vector transmission.

Medición de la repercusión de las relaciones públicas : hacia un estándard internacional

La persistència de la crisi econòmica suposa una amenaça constant al món de la comunicació, especialment per les dimensions dels pressupostos de publicitat, i ha fomentat que els directors de marketing exigeixin retorn, medició i la màxima eficiència en les seves inversions. El clipping de mitjans s’ha convertit en una eina imprescindible per valorar l’eficàcia, comprendre la repercusió, conèixer el retorn d’inversió aconseguit, en definitiva, analitzar si sh´an complert els objetius de la campaña de publicitat. No només es tracta d’una forma de conèixer les aparicions aconseguides en els mitjans, sinó també de reportar al client els assoliments obtinguts. Aquest estudi pretén demostrar la importància d’establir unes pautes i uns paràmetres universals en la valoració de la comunicació d’una marca, producte o servei en els mitjans de comunicació. L’anàlisi que s’ha dut a terme en aquest treball es compon d’opinions de diversos professionals del sector, bibliografia i comparacions amb altres estudis de la mateixa temàtica en altres països.

El impacto de los acuerdos de asociación en las relaciones comerciales entre la Unión Europea y América Latina

Durant diverses dècades les relacions entre la Unió Europea (UE) i Amèrica Llatina es caracteritzaven pel model tradicional de "ajuda sense comerç" fins els anys 1995, que amb acords de quarta generació impulsar el començament del nou instrument. Els acords d'associació (AdA) introdueixen com una novetat tres pilars (diàleg polític, de cooperació i comercial) i centren l'atenció en les relacions comercials, liberalitzen el comerç i estableixen un nou model d'associació biregional. Aquest treball de recerca analitza els AdA de la UE amb països o grups de països llatinoamericans i el seu impacte en les relacions comercials entre la UE i Amèrica Llatina.

Relaciones UE-Ucrania 1991-2003: Una política de reacción

El estudio revisa la evolución de los instrumentos de la acción exterior de la CE/UE hacia Ucrania desde la independencia de este país, en diciembre de 1991. Las principales conclusiones del estudio son: 1) Ucrania ha ido ascendiendo de manera lineal en la agenda de política exterior de la Unión. 2) La prioridad que ha guiado la acción exterior hacia Ucrania ha sido el mantenimiento de la estabilidad en este país para evitar las externalidades negativas que su desestabilización podría comportar para la seguridad de la Unión. 3) Aunque el interés securitario ha sido fundamental a lo largo de todo el período analizado, la agenda de seguridad de la UE se ha ampliado considerablemente. 3) La política de la UE hacia Ucrania se ha guiado más por la reacción ante los acontecimientos en el contexto europeo e internacional que por un diseño o estrategia clara hacia este país. 4) La política de vecindad intenta paliar este déficit de estrategia.