Research plan discussion: The socio-technical construction of MOOCs and educator practices in HE

In this seminar slot, we will discuss Steve's research aims and plan. Massive open online courses (MOOCs) have received substantial coverage in mainstream sources, academic media, and scholarly journals, both negative and positive. Numerous articles have addressed their potential impact on Higher Education systems in general, and some have highlighted problems with the instructional quality of MOOCs, and the lack of attention to research from online learning and distance education literature in MOOC design. However, few studies have looked at the relationship between social change and the construction of MOOCs within higher education, particularly in terms of educator and learning designer practices. This study aims to use the analytical strategy of Socio-Technical Interaction Networks (STIN) to explore the extent to which MOOCs are socially shaped and their relationship to educator and learning designer practices. The study involves a multi-site case study of 3 UK MOOC-producing universities and aims to capture an empirically based, nuanced understanding of the extent to which MOOCs are socially constructed in particular contexts, and the social implications of MOOCs, especially among educators and learning designers.

Diversity Challenge project

Investigacion sobre las personas incapacitadas y sus necesidades a la hora de entrar a una universidad. Diferencias en los difernetes paises, recomendaciones para lograr suplir las necesidades unicas que ellos necesitan.

"Identification and Diversity of Killer Cell Ig-Like Receptors in Aotus vociferans, a New World Monkey "

Previous BAC clone analysis of the Platyrrhini owl monkey KIRs have shown an unusual genetic structure in some loci. Therefore, cDNAs encoding KIR molecules from eleven Aotus vociferans monkeys were characterized here; tenputative KIR loci were found, some of which encoded atypical proteins such as KIR4DL and transcripts predicted to encode a D0+D1 configuration (AOTVOKIR2DL1*01v1) which appear to be unique in the Aotus genus. Furthermore, alternative splicing was found as a likely mechanism for producing activator receptors in A. vociferans species. KIR proteins from New World monkeys may be split into three new lineages according to domain by domain phylogenetic analysis. Although the A. vociferans KIR family displayed a high divergence among paralogous genes, individual loci were limited in their genetic polymorphism. Selection analysis showed that both constrained and rapid evolution may operate within the AvKIR family. The frequent alternative splicing (as a likely mechanism generating activator receptors), the presence of KIR4DL and KIR2DL1 (D0+D1) molecules and other data reported here suggest that the KIR family in Aotus has had a rapid evolution, independent from its Catarrhini counterparts.from its Catarrhini counterparts.

"Genetic Diversity and Selection in Three Plasmodium vivax Merozoite Surface Protein 7 (Pvmsp-7) Genes in a Colombian Population"

A completely effective vaccine for malaria (one of the major infectious diseases worldwide) is not yet available; different membrane proteins involved in parasite-host interactions have been proposed as candidates for designing it. It has been found that proteins encoded by the merozoite surface protein (msp)-7 multigene family are antibody targets in natural infection; the nucleotide diversity of three Pvmsp-7 genes was thus analyzed in a Colombian parasite population. By contrast with P. falciparum msp-7 loci and ancestral P. vivax msp-7 genes, specie-specific duplicates of the latter specie display high genetic variability, generated by single nucleotide polymorphisms, repeat regions, and recombination. At least three major allele types are present in Pvmsp-7C, Pvmsp-7H and Pvmsp-7I and positive selection seems to be operating on the central region of these msp-7 genes. Although this region has high genetic polymorphism, the C-terminus (Pfam domain ID: PF12948) is conserved and could be an important candidate when designing a subunit-based antimalarial vaccine.

Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population

Background Plasmodium vivax is one of the five species causing malaria in human beings, affecting around 391 million people annually. The development of an anti-malarial vaccine has been proposed as an alternative for controlling this disease. However, its development has been hampered by allele-specific responses produced by the high genetic diversity shown by some parasite antigens. Evaluating these antigens’ genetic diversity is thus essential when designing a completely effective vaccine. Methods The gene sequences of Plasmodium vivax p12 (pv12) and p38 (pv38), obtained from field isolates in Colombia, were used for evaluating haplotype polymorphism and distribution by population genetics analysis. The evolutionary forces generating the variation pattern so observed were also determined. Results Both pv12 and pv38 were shown to have low genetic diversity. The neutral model for pv12 could not be discarded, whilst polymorphism in pv38 was maintained by balanced selection restricted to the gene’s 5′ region. Both encoded proteins seemed to have functional/structural constraints due to the presence of s48/45 domains, which were seen to be highly conserved.

Genetic diversity and selection in three plasmodium vivax merozoite surface protein 7 (pvmsp-7) genes in a colombian population

A completely effective vaccine for malaria (one of the major infectious diseases worldwide) is not yet available; different membrane proteins involved in parasite-host interactions have been proposed as candidates for designing it. It has been found that proteins encoded by the merozoite surface protein (msp)-7 multigene family are antibody targets in natural infection; the nucleotide diversity of three Pvmsp-7 genes was thus analyzed in a Colombian parasite population. By contrast with P. falciparum msp-7 loci and ancestral P. vivax msp-7 genes, specie-specific duplicates of the latter specie display high genetic variability, generated by single nucleotide polymorphisms, repeat regions, and recombination. At least three major allele types are present in Pvmsp-7C, Pvmsp-7H and Pvmsp-7I and positive selection seems to be operating on the central region of these msp-7 genes. Although this region has high genetic polymorphism, the C-terminus (Pfam domain ID: PF12948) is conserved and could be an important candidate when designing a subunit-based antimalarial vaccine.

Cultural diversity : obstacle or help in building european unity?. 'La diversidad cultural : ¿obstáculo o ayuda para la construcción de la unidad europea?'.

Resumen tomado del autor

Religious diversity and intercultural education : a reference book for schools.'Diversidad religiosa y educación intercultural : un libro de consulta para las escuelas'.

Resumen tomado de la publicación. El manual es el resultado de un proyecto del Consejo de Europa llevado a cabo entre 2002 y 2005 titulado 'The Challenge of intercultural education today: religious diversity and dialogue in Europe' (El reto de la educación intercultural hoy: diversidad religiosa y diálogo en Europa)

The diversity of species.

Se estudian las diferencias físicas y genéticas que afectan a las distintas formas de vida que existen sobre la Tierra, cuya diversidad se calcula en catorce millones de especies de plantas, animales, algas, hongos y bacterias. Debido a esta gran diversidad de especies, ha sido necesario crear una clasificación, desde los más simples organismos, en la parte inferior hasta los más sofisticados en la superior. La evolución de las especies se realiza por el mecanismo de la selección natural estudiada por Darwin, que proporciona con el paso del tiempo adaptaciones o ajustes que preparan a un organismo para vivir en un lugar particular. Al final de cada tema aparece la reseña de científicos que han descrito y estudiado esta diversidad, y al final del libro hay una pequeña bibliografía y direcciones de páginas web.

The diversity of life : from single cells to multicellular organisms.

Este título pertenece a una serie que ofrece en profundidad una visión de las células en todo el mundo vivo, su estructura y los procesos en que se basa la vida en la Tierra. Explora cómo las células han formado la vida que vemos a nuestro alrededor. Nadie sabe cuántos millones de especies diferentes pueden existir en nuestro planeta, y cada año se descubren otras nuevas. Los científicos clasifican los seres vivos en distintos grupos para ayudar a dar sentido a esta diversidad de la vida. Esta publicación examina cómo ha cambiado la clasificación a lo largo del tiempo, incluyendo una reciente propuesta para clasificar a los seres vivos en tres dominios en lugar de seis reinos. Tiene índice, glosario, referencias bibliográficas y un gráfico ramificado para dar una idea aproximada de la diversidad del reino animal.

Evaluaci??n de las medidas de atenci??n a la diversidad de la educaci??n primaria en Galicia : impacto escolar. 'Evaluation of the measures of attention to the diversity in the primary education in Galicia : school impact'

Resumen tomado de la publicaci??n. Con el apoyo econ??mico del departamento MIDE de la UNED

Teacher efficacy scale for classroom diversity (TESCD) : a validation study. 'Escala de eficacia del profesorado de la diversidad en el aula (TESCD) : un estudio de validación'.

Monográfico con el título: 'La competencia de aprender a aprender y el aprendizaje autorregulado: posicionamientos teóricos'. Resumen basado en el de la publicación

Human development in a globalized world : education towards peace, cultural diversity and sustainable development

Monogr??fico con el t??tulo: "La educaci??n como quehacer de convicciones : homenaje acad??mico a Jos?? Antonio Ib????ez-Mart??n"

La Relevancia de las creencias sobre diversidad cultural en la formación del docente = The significance of beliefs on cultural diversity in the training of teachers

Uno de los rasgos más característicos de los centros educativos en estos momentos lo constituye la presencia de un alumnado culturalmente diverso. Gestionar de forma adecuada tal diversidad cultural y asegurar una educación de calidad para todos/as que posibilite la construcción de una ciudadanía plural, intercultural y democrática se plantea como uno de los retos más importantes a los que se enfrenta el sistema educativo en general y el profesorado en particular