999 resultados para Celulas - Proliferação
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Pós-graduação em Zootecnia - FMVZ
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Pós-graduação em Fisioterapia - FCT
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Pós-graduação em Patologia - FMB
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Pós-graduação em Biotecnologia Animal - FMVZ
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Pós-graduação em Biotecnologia Animal - FMVZ
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Pós-graduação em Odontologia - FOAR
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Pós-graduação em Odontologia - ICT
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Human salivary gland tumors originated from intercalated ducts present a broad range of histologic and cytologic patterns, mainly due to the presence of myoepithelial cells. The aim of this study is to verify the differentiation grade of neoplastic cells and a possible relation between myoepithelial cell differentiation and the presence of luminal secretory contents. The expression of vimentin and cytokeratin (CK) intermediate filaments, actin myofilament and epithelial membrane antigen (EMA) was investigated by double labeling immunocytochemical technique, in thirty salivary gland neoplasms: 5 pleomorphic adenomas, 5 myoepitheliomas, 3 basal cell adenomas, 7 adenoid cystic carcinomas (ACC) and 10 polimorphous low grade adenocarcinomas (PLGA). Tumors with intercalated duct differentiation (pleomorphic adenomas, basal cell adenomas and ACC) express CKs 7, 8, 18 and 19 in the luminal cells and coexpress eventually CK14 with these CKs. Some luminal cells stained with anti-EMA antibody, mainly where a secretory content in the lumen was observed. Outer ductal cells and other myoepithelial-like cells express vimentin, sometimes coexpressing actin and/or CK14 with vimentin. Plasmacytoid cells in myoepitheliomas and pleomorphic adenomas express vimentin and rarely CKs 7, 8, 18 and 19, sometimes coexpressing these CKs with CK14 but they are negative for the remaining antigens. Tumors without intercalated duct differentiation (solid basal cell adenoma and PLGA) express vimentin and CKs 7, 8, 14 and 18, sometimes coexpressing CKs 8 and 18 with CK14. In conclusion, in tumors with intercalated duct differentiation, myoepithelial cells express vimentin and sometimes coexpress actin and/or CK14 with vimentin, never coexpressing other CKs with vimentin. CK14 and actin are independently expressed by myoepithelial cells, so their expression is probably induced by different stimulus. However, the secretory function of luminal cells, visualized by EMA staining, ....
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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In 2011, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC), created to administer the Common System of Accounting and Control of Nuclear Material (CSAC) has completed twenty years of existence. ABACC and the Quadripartite Agreement established with International Atomic Energy Agency (IAEA) are a special system of safeguards that presents itself as an important example of regional contribution to global nuclear proliferation. The paper presents some considerations about the process of understanding between Brazil and Argentina that resulted in the creation of ABACC, indicates succinctly some theoretical explanations of international relations for this process and, from some features of the Agency, relates how the ABACC experience could support nuclear weapons free zones.
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This article analyses the constitutions of the Philosophy of Education’s field in Brazil, from 1990 to the present day, with the purpose of analyzing the genealogy of his “crisis” as a discipline, discussing the dilemmas of its development and to indicate their main challenges today. For such purposes, by means of a genealogical method, we analyze the conceptions of philosophy of education drawn from the theoretical perspective, as well as rebuild historically the clashes caused about certain topics and, particularly, about the human formation. We conclude that the thematic shifts produced and the proliferation of those perspectives were responsible for producing lands to the dialogue between them, however, this strategy does not alleviate some problems of Philosophy of Education in Brazil, demonstrating the presence of two philosophical traditions in the current debate and demanding position of those who work in this field of research and teaching in relation to them.
Variação espaço-temporal de atributos ecológicos da ictiofauna de um grande reservatório Neotropical
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Pós-graduação em Aquicultura - FCAV
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Pós-graduação em Química - IQ
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)