Hyaluronan Synthesis and Myogenesis: A requirement for hyaluronan synthesis during myogenic differentiation independent of pericullular matrix formation

Background
The role endogenously synthesized hyaluronan plays in myogenesis is not yet known.

Results
Hyaluronan synthase genes were expressed during skeletal muscle growth and regeneration; inhibiting these synthases prevents myoblast differentiation and fusion.

Conclusion
Endogenous hyaluronan synthesis is required for myogenic differentiation.

Significance
The necessity for hyaluronan in myogenesis has implications when considering promoting muscle growth or regeneration.

Beyond the primary influences of parents and peers on very young adolescent alcohol use: Evidence of independent community associations

This study examined the extent to which young adolescent alcohol use was related to alcohol-related norms and law enforcement of underage alcohol use, after accounting for known strong parent and peer correlates. Our sample consisted of 7,674 students (X̅ age = 12 years) from 30 Australian communities. Two-level (individuals nested within communities) binary logistic regression was used to examine relationships between recent alcohol use (last 30 days) and perceived community norms about alcohol use, perceived law enforcement of underage alcohol use, parent alcohol use, parent permissiveness of adolescent alcohol use, peer alcohol use, and demographic factors. Results indicated that community norms and perceived law enforcement of alcohol use were associated with alcohol use and this association was independent of parent and peer factors. After accounting for proximal social correlates, community factors were significantly associated with alcohol use among very young adolescents.

A methodological approach to quality assurance of programs in an independent school

This paper reports on ways in which one Australian independent school seeks to develop and sustain best practice and academic integrity in its programs through a quality assurance system of ongoing program reviews, and findings of a study that we conducted into staff perceptions of the different program reviews. First, we outline the overarching methodological and conceptual approaches used in the school’s program reviews. Second, we present and discuss the findings of the study.

A review of program evaluations in an Australian independent school: participants’ perspectives

This paper reports on ways in which one Australian independent school seeks to develop and sustain best practice and academic integrity in its programs through a system of ongoing program evaluation, involving a systematic, cyclical appraisal of the school’s suite of six faculties. A number of different evaluation methods have been and continue to be used, each developed to best suit the particular program under evaluation. In order to gain an understanding of the effectiveness of this process, we conducted a study into participants’ perceptions of the strengths and weaknesses of the four program evaluations undertaken between 2009 and 2011. Drawing on documentary analysis of the evaluation reports and analysis of questionnaire data from the study participants, a number of findings were generated. These findings are provided and discussed, together with suggestions about ways in which the conceptualisation and conduct of school program evaluations might be enhanced.