Heckscher-Ohlin : evidence from virtual trade in value added

The fragmentation of production chains across borders is one of the most distinctive feature of the last 30 years of globalization. Nonetheless, our understanding of its implications for trade theory and policy is only in its infancy. We suggest that trade in value added should follow theories of comparative advantage more closely than gross trade, as value-added flows capture where factors of production, e.g. skilled and unskilled labor, are used along the global value chain. We find empirical evidence that Heckscher-Ohlin theory does predict manufacturing trade in value-added, and it does so better than for gross shipment flows. While countries exports across a broad range of sectors, they contribute more value-added in techniques using their abundant factor intensively.

Standards and specifications to manage accessibility issues in e-learning

Despite the acknowledged need of providing a personalized and adaptive learning process for all, current learning management systems do not properly cover personalization and accessibility issues and they are still struggling to support the reusability requirements coming from the pervasive usage of standards. There is a lack of frameworks for providing layered-based infrastructure covering the interoperability required to manage the whole range of standards, applications and services needed to meet accessibility and adaptations needs of lifelong learning services.

Physiological features of Schizosaccharomyces pombe of interest in the making of white wines

This work studies the physiology of Schizosaccharomyces pombe strain 938 in the production of white wine with high malic acid levels as the sole fermentative yeast, as well as in mixed and sequential fermentations with Saccharomyces cerevisiae Cru Blanc. The induction of controlled maloalcoholic fermentation through the use of Schizosaccharomyces spp. is now being viewed with much interest. The acetic, malic and pyruvic acid concentrations, relative density and pH of the musts were measured over the entire fermentation period. In all fermentations in which Schizo. pombe 938 was involved, nearly all the malic acid was consumed and moderate acetic concentrations produced. The urea content and alcohol level of these wines were notably lower than in those made with Sacch. cerevisiae Cru Blanc alone. The pyruvic acid concentration was significantly higher in Schizo. pombe fermentations. The sensorial properties of the different final wines varied widely.

Repetitio. ru. [et] ca. p[er] v[est]ras de donationib[us] int[er] virum [et] vxorem / edita a Joa[n]ne lupi de palacios ruuios ...

Sign.: []2, a-z8, [et]8, [cum]8, [rum]8, 2a-2d8, 2e-2f6, A10, a8, b10

Tractatus contra hereticam prauitate[m] ; et etia[m] tractatus de irrigularitate [sic] / editi, per Gundissaluum de villadiego ...

Nouiter impressi ac alme correcti, cum reportorio

Commentarius / Caesaris.

Pie de imp. tomado del colofón

Opus egregiu[m] / diui bernardi super cantica canticoru[m] salomonis tam co[n]templatiue q[uam] actiue vite cultorib[us] precipue vero p[rae]dicatoribus accommodatissimum feliciter incipit ; multa diligentia castigatum ac emendatum per magistru[m] Iohanne

Huecos para iniciales con letras de aviso

Preclarissima [et] inestimabilis doctrine atq[ue] vtilitatis Diui Aurelij Augustini sermonu[m] opera.

Marca tip. de Berthold Rembolt en port. (Renouard, 961)

Preclarissima [et] inestimabilis doctrine atq[ue] vtilitatis Diui Aurelij Augustini sermonu[m] opera.

Marca tip. de Berthold Rembolt en port. (Renouard, 961)

Crowdsourcing malaria parasite quantification: an online game for analyzing images of infected thick blood smears

Background: There are 600,000 new malaria cases daily worldwide. The gold standard for estimating the parasite burden and the corresponding severity of the disease consists in manually counting the number of parasites in blood smears through a microscope, a process that can take more than 20 minutes of an expert microscopist’s time. Objective: This research tests the feasibility of a crowdsourced approach to malaria image analysis. In particular, we investigated whether anonymous volunteers with no prior experience would be able to count malaria parasites in digitized images of thick blood smears by playing a Web-based game. Methods: The experimental system consisted of a Web-based game where online volunteers were tasked with detecting parasites in digitized blood sample images coupled with a decision algorithm that combined the analyses from several players to produce an improved collective detection outcome. Data were collected through the MalariaSpot website. Random images of thick blood films containing Plasmodium falciparum at medium to low parasitemias, acquired by conventional optical microscopy, were presented to players. In the game, players had to find and tag as many parasites as possible in 1 minute. In the event that players found all the parasites present in the image, they were presented with a new image. In order to combine the choices of different players into a single crowd decision, we implemented an image processing pipeline and a quorum algorithm that judged a parasite tagged when a group of players agreed on its position. Results: Over 1 month, anonymous players from 95 countries played more than 12,000 games and generated a database of more than 270,000 clicks on the test images. Results revealed that combining 22 games from nonexpert players achieved a parasite counting accuracy higher than 99%. This performance could be obtained also by combining 13 games from players trained for 1 minute. Exhaustive computations measured the parasite counting accuracy for all players as a function of the number of games considered and the experience of the players. In addition, we propose a mathematical equation that accurately models the collective parasite counting performance. Conclusions: This research validates the online gaming approach for crowdsourced counting of malaria parasites in images of thick blood films. The findings support the conclusion that nonexperts are able to rapidly learn how to identify the typical features of malaria parasites in digitized thick blood samples and that combining the analyses of several users provides similar parasite counting accuracy rates as those of expert microscopists. This experiment illustrates the potential of the crowdsourced gaming approach for performing routine malaria parasite quantification, and more generally for solving biomedical image analysis problems, with future potential for telediagnosis related to global health challenges.

Clarissimi ... Pauli Soncinatis ... Ordinis Predicatorum, Diuinum Epitoma Questionum in quatuor libros Sententiarum a ... Joanne Capreolo Tholosano disputatarum / his additisque idem morte preuentus perficere nequiuit, per fratem Isidorum de Isolanis ...

Capitulares grab. xil.

Clarissimi ... Pauli Soncinatis ... Ordinis Predicatorum, Diuinum Epitoma Questionum in quatuor libros Sententiarum a ... Joanne Capreolo Tholosano disputatarum / his additisque idem morte preuentus perficere nequiuit, per fratem Isidorum de Isolanis ...

Capitulares grab. xil.

Effect of misorientation on the compression of highly anisotropic single-crystal micropillars

The effect of crystal misorientation, geometrical tilt, and contact misalignment on the compression of highly anisotropic single crystal micropillars was assessed by means of crystal plasticity finite element simulations. The investigation was focused in single crystals with the NaCl structure, like MgO or LiF, which present a marked plastic anisotropy as a result of the large difference in the critical resolved shear stress between the “soft” {110}〈110〉 and the “hard” {100}〈110〉 active slip systems. It was found that contact misalignment led to a large reduction in the initial stiffness of the micropillar in crystals oriented in the soft and hard direction. The crystallographic tilt did not modify, however, the initial crystal stiffness. From the viewpoint of the plastic response, none of the effects analyzed led to significant differences in the flow stress when the single crystals were oriented along the “soft” [100] direction. Large differences were found, however, if the single crystal was oriented in the “hard” [111] direction as a result of the activation of the soft slip system. Numerical simulations were in very good agreement with experimental literature data.

In hoc volumine beati Bonaue[n]ture subiecta comprehenduntur : Oratio Octauiani in vitam beati Bonauenture ; Libellus de reductione artium ad theologiam ; Tractatus de paup[eri]tate [Christi] [con]tra mag[ist]r[u]m, vvilhelmum ; Tractatulus de quinq[ue] f

Impresor y año tomados del colofón

In hoc volumine beati Bonaue[n]ture subiecta comprehenduntur : Oratio Octauiani in vitam beati Bonauenture ; Libellus de reductione artium ad theologiam ; Tractatus de paup[eri]tate [Christi] [con]tra mag[ist]r[u]m, vvilhelmum ; Tractatulus de quinq[ue] f

Impresor y año tomados del colofón