O herói sublime: figuras e figuração

Tese dout., Literatura Comparada, Faculdade de Letras da Universidade de Lisboa, 2006

Padrões verticais e inter-anuais nas assembleias de larvas de peixe junto ao substrato rochoso do Parque Marinho da Arrábida

Dissertação de mest., Biologia Marinha, Faculdade de Ciências e Tecnologia, Univ. do Algarve, 2009

Variabilidade do "upwelling" costeiro durante o holocénico nas margens atlânticas ocidental e meridional da Península Ibérica

Tese de dout., Ciências do Mar, Faculdade de Ciências do Mar e do Ambiente, Univ. do Algarve, 2005

An address delivered before the South-Carolina institute, at its first annual fair

This document contains an address by James H. Hammond , delivered before the South Carolina Institute, held at Military Hall It mentions the resolutions that were proposed and adopted including an acknowledgements for the very able and eloquent address, appointment of five committee members for communication and to request a copy of the address for publication with James H. Hammond.

Speech of Hon. James H. Hammond, of South Carolina, on the relation of states; delivered in the Senate of the United States, May 21, 1860

The speech is a response by Hon. James H. Hammond as to whether or not the territorial governments established by Congress have the power to define and declare what shall be and what shall not be property within the territorial boundaries. The speech goes on to discuss colonists who went to newly purchased territory and claimed land as their own. He argues whether or not these people have sovereignty of the land over the government.

Poetizando a história nacional : ficcionalização da história e método historiográfico em José de Alencar

Tese de doutoramento, História (História e Cultura do Brasil), Universidade de Lisboa, Faculdade de Letras, 2014

Virtual Infants in Zoo Indigo’s Under the Covers This is Now, This is Live…

The article This is Live this is now (2011), contextualises the performance Under the Covers (2009) by Zoo Indigo. The journal article is written by Ildiko Rippel on behalf of Zoo Indigo theatre company (Rosie Garton and Ildiko Rippel) and it is published in the online Body, Space and Technology Journal:

New insights into host-parasite ubiquitin proteome dynamics in P. falciparum infected red blood cells using a TUBEs-MS approach

Malaria, caused by Plasmodium falciparum (P. falciparum), ranks as one of the most baleful infectious diseases worldwide. New antimalarial treatments are needed to face existing or emerging drug resistant strains. Protein degradation appears to play a significant role during the asexual intraerythrocytic developmental cycle (IDC) of P. falciparum. Inhibition of the ubiquitin proteasome system (UPS), a major intracellular proteolytic pathway, effectively reduces infection and parasite replication. P. falciparum and erythrocyte UPS coexist during IDC but the nature of their relationship is largely unknown. We used an approach based on Tandem Ubiquitin-Binding Entities (TUBEs) and 1D gel electrophoresis followed by mass spectrometry to identify major components of the TUBEs-associated ubiquitin proteome of both host and parasite during ring, trophozoite and schizont stages. Ring-exported protein (REX1), a P. falciparum protein located in Maurer's clefts and important for parasite nutrient import, was found to reach a maximum level of ubiquitylation in trophozoites stage. The Homo sapiens (H. sapiens) TUBEs associated ubiquitin proteome decreased during the infection, whereas the equivalent P. falciparum TUBEs-associated ubiquitin proteome counterpart increased. Major cellular processes such as DNA repair, replication, stress response, vesicular transport and catabolic events appear to be regulated by ubiquitylation along the IDC P. falciparum infection.

A paisagem espanhola nas viagens de Luciano Cordeiro

Será pela sua intensa actividade ao serviço da defesa das colónias, bem como pelas suas produções ensaísticas e de crítica literária que a posteridade lembrará Luciano Cordeiro. Já as duas narrativas de viagem – Viagens: Espanha e França (1874) e Viagens: França, Baviera, Áustria e Itália (1875) – do Fundador e da Sociedade de Geografia de Lisboa são deveras desconhecidas. Nelas se projecta a particular geografia do olhar do polígrafo português em viagem pela Europa e cuja reconstituição é o alvo deste estudo. Os objectivos perseguidos por este trabalho são, por conseguinte, a percepção e reconstrução do espaço de Luciano Cordeiro, nomeadamente da Espanha, tentando dilucidar o que na obra é de cariz geográfico, repousando sobre uma análise descritivo-realista da paisagem, e o que é de cariz literário ou ficcionado.

Virtuosismo para instrumentário de sopro em Lisboa (1821-1870)

Dissertação apresentada para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Ciências Musicais

Série das invasões francesas”: análise da imagética. Uma visão Ibérica sobre um inimigo exterior

Dissertação de Mestrado em História de Arte - Variante Contemporânea

PFO closure vs. medical therapy in cryptogenic stroke or transient ischemic attack: A systematic review and meta-analysis.

BACKGROUND/OBJECTIVES: This study aims to assess whether patent foramen ovale (PFO) closure is superior to medical therapy in preventing recurrence of cryptogenic ischemic stroke or transient ischemic attack (TIA). METHODS: We searched PubMed for randomized trials which compared PFO closure with medical therapy in cryptogenic stroke/TIA using the items: "stroke or cerebrovascular accident or TIA" and "patent foramen ovale or paradoxical embolism" and "trial or study". RESULTS: Among 650 potentially eligible articles, 3 were included including 2303 patients. There was no statistically significant difference between PFO-closure and medical therapy in ischemic stroke recurrence (1.91% vs. 2.94% respectively, OR: 0.64, 95%CI: 0.37-1.10), TIA (2.08% vs. 2.42% respectively, OR: 0.87, 95%CI: 0.50-1.51) and death (0.60% vs. 0.86% respectively, OR: 0.71, 95%CI: 0.28-1.82). In subgroup analysis, there was significant reduction of ischemic strokes in the AMPLATZER PFO Occluder arm vs. medical therapy (1.4% vs. 3.04% respectively, OR: 0.46, 95%CI: 0.21-0.98, relative-risk-reduction: 53.2%, absolute-risk-reduction: 1.6%, number-needed-to-treat: 61.8) but not in the STARFlex device (2.7% vs. 2.8% with medical therapy, OR: 0.93, 95%CI: 0.45-2.11). Compared to medical therapy, the number of patients with new-onset atrial fibrillation (AF) was similar in the AMPLATZER PFO Occluder arm (0.72% vs. 1.28% respectively, OR: 1.81, 95%CI: 0.60-5.42) but higher in the STARFlex device (0.64% vs. 5.14% respectively, OR: 8.30, 95%CI: 2.47-27.84). CONCLUSIONS: This meta-analysis does not support PFO closure for secondary prevention with unselected devices in cryptogenic stroke/TIA. In subgroup analysis, selected closure devices may be superior to medical therapy without increasing the risk of new-onset AF, however. This observation should be confirmed in further trials using inclusion criteria for patients with high likelihood of PFO-related stroke recurrence.

Le Rappel / directeur gérant : Albert Barbieux

1874/07/06 (N1578).