Das inter-etnicidades em processos de inserção social diferenciadas às dinâmicas do sistema-mundo: uma abordagem estrutural-dinâmica

Em pesquisas anteriores, procurámos mostrar que (i) as representações identitárias possuem uma estrutura multidimensional, cujos níveis (pessoal, bio-cultural, sócio-histórico / político, ideal, «moral», etc.) estão inter-relacionados, e formam um sistema identitário pessoal, se bem que partilhado, em proporções variáveis, com os outros emissores identitários inseridos na mesma categoria sócio-histórica; (ii) sistema identitário esse detentor de potencialidades estratégicas (Kastersztein, 1990) - ideológicas, simbólicas e fantasmáticas -, derivadas da articulação inconsciente entre os diferentes níveis mobilizados. Tentámos evidenciar ainda, no nível mais abrangente das representações identitárias dos grupos sócio-históricos, (iii) como o grau de sobreposição e convergência das atribuições identitárias, tanto ao grupo.de identificação como aos grupos de comparação interactiva, é parcial, indiciando estratégias de maior ou menor distanciação / aproximação identitária inter-nacional ou inter-étnica; (iv) e como, no seu conjunto, as representações identitárias apresentam uma lógica e uma economia retórica, tendenciosa e performativa (pro domo sua), criando para os sujeitos, no interior dos seus grupos, e para os seus grupos identitários, na comparação com os outros, uma imagem de primo inter pares, na medida em que constroiem como «real» o «real identitariamente conveniente» e não aquele que «objectivamente » é «objectivado» (em termos de poder tecnológico, econômico ou militar).

Viver sem Medo - Projeto de Intervenção com um Grupo de Mulheres em situação de Vulnerabilidade Social

O presente relatório, fundamentado teoricamente, surge do desenvolvimento de um projeto de Educação e Intervenção Social com um grupo de Mulheres, denominado “Mais Valentes”, participantes no Projeto EntrEscolhas – Geração D’Ouro, com base na metodologia de investigaçãoação participativa, inserida no paradigma socio-crítico. O Projeto “Viver sem medo” foi desenvolvido a partir da finalidade de capacitar as mulheres do Grupo Mais Valentes para a tomada de decisão sobre os seus percursos de vida, tendo em conta o seu papel nas diferentes esferas da sociedade e, essencialmente, na família. Neste sentido, recorreram-se a técnicas e métodos de investigação que permitiram a construção do conhecimento sobre o grupo e cada uma das suas participantes, identificando-se problemas, necessidades, potencialidades e objetivos que pudessem responder aos anteriores. Ao longo do relatório é apresentada a construção do conhecimento sobre a realidade e o desenho e desenvolvimento do projeto concretizado conjuntamente com as participantes e, ainda, com contributos do e das Profissionais do Projeto EntrEscolhas – Geração D’Ouro. Neste sentido, foram realizados Encontros semanais com o grupo “Mais Valentes” e, posteriormente, ações com o objetivo de proporcionar a reflexão sobre os papéis sociais e familiares de género, o desenvolvimento de competências de literacia escolar e social e com vista à promoção de um melhor relacionamento interpessoal que permita a partilha e o diálogo. Por forma a avaliar todo o processo, recorreu-se ao modelo de avaliação CIPP, no sentido de se obter uma visão integral de todo o Projeto “Viver sem medo” e, assim, conseguir concretizar uma avaliação sistemática e contínua do mesmo, com base nas vivências de participação no projeto e opiniões das Mulheres e, assim, se possibilitar as mudanças desejadas, num clima de confiança e apoio mútuo.

Social Media Integration in Video Games GameNshare: A Social Overlay for Desktop Games

The ever increasing popularity of social media makes it a promising source for the personalization of gameplay experiences. Furthermore, involving social network friends in a game can greatly enrich the satisfaction of the player and also attract potential novel players to a game. This master thesis describes a social overlay designed for desktop games, called GameNshare. It allows players to easily capture and share with multiple social networks game-related screenshots, videos and stories. Additionally, it also provides asynchronous multiplayer game mechanics to directly integrate social network friends in the game. GameNshare was designed to interact with the users in a non-intrusive way allowing them to be in complete control of what is shared. It prevents unsolicited sharing of messages, a key problem in social media integration tools, by the use of built-in message monitoring and anti-spam measures. GameNshare was specially designed for players aged from 18 to 25 years that are regular users of Twitter and Facebook. It was tested by a group of 10 individuals from the target age range that were surveyed to capture their insights on the use of the social overlay. The implemented GameNshare features were well accepted by the testers that were also useful in highlighting features for future development. GameNshare ultimate goal is to make players look and ask for social integration and allow them to take full advantage of their social communities to improve gaming experiences.

Development of The Viking Speech Scale to Classify the Speech of Children with Cerebral Palsy

Surveillance registers monitor the prevalence of cerebral palsy and the severity of resulting impairments across time and place. The motor disorders of cerebral palsy can affect children’s speech production and limit their intelligibility. We describe the development of a scale to classify children’s speech performance for use in cerebral palsy surveillance registers, and its reliability across raters and across time. Speech and language therapists, other healthcare professionals and parents classified the speech of 139 children with cerebral palsy (85 boys, 54 girls; mean age 6.03 years, SD 1.09) from observation and previous knowledge of the children. Another group of health professionals rated children’s speech from information in their medical notes. With the exception of parents, raters reclassified children’s speech at least four weeks after their initial classification. Raters were asked to rate how easy the scale was to use and how well the scale described the child’s speech production using Likert scales. Inter-rater reliability was moderate to substantial (k > .58 for all comparisons). Test–retest reliability was substantial to almost perfect for all groups (k > .68). Over 74% of raters found the scale easy or very easy to use; 66% of parents and over 70% of health care professionals judged the scale to describe children’s speech well or very well. We conclude that the Viking Speech Scale is a reliable tool to describe the speech performance of children with cerebral palsy, which can be applied through direct observation of children or through case note review.

Prisão com fronteiras: relações inter-étnicas em meio prisional. Estudo de caso no estabelecimento prisional de Carregueira

Dissertação apresentada para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Migrações, Inter-etnicidades e Transnacionalismo

Locally Advanced and Metastatic Prostate Cancer Treated with Intermittent Androgen Monotherapy or Maximal Androgen Blockade: Results from a Randomised Phase 3 Study by the South European Uroncological Group

BACKGROUND: Few randomised studies have compared antiandrogen intermittent hormonal therapy (IHT) with continuous maximal androgen blockade (MAB) therapy for advanced prostate cancer (PCa). OBJECTIVE: To determine whether overall survival (OS) on IHT (cyproterone acetate; CPA) is noninferior to OS on continuous MAB. DESIGN, SETTING, AND PARTICIPANTS: This phase 3 randomised trial compared IHT and continuous MAB in patients with locally advanced or metastatic PCa. INTERVENTION: During induction, patients received CPA 200 mg/d for 2 wk and then monthly depot injections of a luteinising hormone-releasing hormone (LHRH; triptoreline 11.25 mg) analogue plus CPA 200 mg/d. Patients whose prostate-specific antigen (PSA) was <4 ng/ml after 3 mo of induction treatment were randomised to the IHT arm (stopped treatment and restarted on CPA 300 mg/d monotherapy if PSA rose to ≥20 ng/ml or they were symptomatic) or the continuous arm (CPA 200 mg/d plus monthly LHRH analogue). OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcome measurement was OS. Secondary outcomes included cause-specific survival, time to subjective or objective progression, and quality of life. Time off therapy in the intermittent arm was recorded. RESULTS AND LIMITATIONS: We recruited 1045 patients, of which 918 responded to induction therapy and were randomised (462 to IHT and 456 to continuous MAB). OS was similar between groups (p=0.25), and noninferiority of IHT was demonstrated (hazard ratio [HR]: 0.90; 95% confidence interval [CI], 0.76-1.07). There was a trend for an interaction between PSA and treatment (p=0.05), favouring IHT over continuous therapy in patients with PSA ≤1 ng/ml (HR: 0.79; 95% CI, 0.61-1.02). Men treated with IHT reported better sexual function. Among the 462 patients on IHT, 50% and 28% of patients were off therapy for ≥2.5 yr or >5 yr, respectively, after randomisation. The main limitation is that the length of time for the trial to mature means that other therapies are now available. A second limitation is that T3 patients may now profit from watchful waiting instead of androgen-deprivation therapy. CONCLUSIONS: Noninferiority of IHT in terms of survival and its association with better sexual activity than continuous therapy suggest that IHT should be considered for use in routine clinical practice.

Multipath inter-domain policy routing

Dissertação submetida para a obtenção do grau de Doutor em Engenharia Electrotécnica e de Computadores

Economic Evaluation of Ticagrelor for Secondary Prevention Following Acute Coronary Syndromes

INTRODUCTION AND OBJECTIVES: To estimate the cost-effectiveness and cost-utility of ticagrelor in the treatment of patients with acute coronary syndromes (unstable angina or myocardial infarction with or without ST-segment elevation), including patients treated medically and those undergoing percutaneous coronary intervention or coronary artery bypass grafting. METHODS: A short-term decision tree and a long-term Markov model were used to simulate the evolution of patients' life-cycles. Clinical effectiveness data were collected from the PLATO trial and resource use data were obtained from the Hospital de Santa Marta database, disease-related group legislation and the literature. RESULTS: Ticagrelor provides increases of 0.1276 life years and 0.1106 quality-adjusted life years (QALYs) per patient. From a societal perspective these clinical gains entail an increase in expenditure of €610. Thus the incremental cost per life year saved is €4780 and the incremental cost per QALY is €5517. CONCLUSIONS: The simulation results show that ticagrelor reduces events compared to clopidogrel. The costs of ticagrelor are partially offset by lower costs arising from events prevented. The use of ticagrelor in clinical practice is therefore cost-effective compared to generic clopidogrel.

Extracting temporal and spatial distributions information about marine mucilage phenomenon based on Modis satellite images; a case study of the Tyrrhenian and the Adriatic Sea, 2010-2012

Dissertation submitted in partial fulfillment of the requirements for the Degree of Master of Science in Geospatial Technologies.

The effect of demand information sharing in a supply chain under demand uncertainty: a simulation study

Dissertação para obtenção do Grau de Mestre em Engenharia e Gestão Industrial

Intravenous Busulfan for Autologous Stem Cell Transplantation in Adult Patients with Acute Myeloid Leukemia: a Survey of 952 Patients on Behalf of the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Oral busulfan is the historical backbone of the busulfan+cyclophosphamide regimen for autologous stem cell transplantation. However intravenous busulfan has more predictable pharmacokinetics and less toxicity than oral busulfan; we, therefore, retrospectively analyzed data from 952 patients with acute myeloid leukemia who received intravenous busulfan for autologous stem cell transplantation. Most patients were male (n=531, 56%), and the median age at transplantation was 50.5 years. Two-year overall survival, leukemia-free survival, and relapse incidence were 67±2%, 53±2%, and 40±2%, respectively. The non-relapse mortality rate at 2 years was 7±1%. Five patients died from veno-occlusive disease. Overall leukemia-free survival and relapse incidence at 2 years did not differ significantly between the 815 patients transplanted in first complete remission (52±2% and 40±2%, respectively) and the 137 patients transplanted in second complete remission (58±5% and 35±5%, respectively). Cytogenetic risk classification and age were significant prognostic factors: the 2-year leukemia-free survival was 63±4% in patients with good risk cytogenetics, 52±3% in those with intermediate risk cytogenetics, and 37 ± 10% in those with poor risk cytogenetics (P=0.01); patients ≤50 years old had better overall survival (77±2% versus 56±3%; P<0.001), leukemia-free survival (61±3% versus 45±3%; P<0.001), relapse incidence (35±2% versus 45±3%; P<0.005), and non-relapse mortality (4±1% versus 10±2%; P<0.001) than older patients. The combination of intravenous busulfan and high-dose melphalan was associated with the best overall survival (75±4%). Our results suggest that the use of intravenous busulfan simplifies the autograft procedure and confirm the usefulness of autologous stem cell transplantation in acute myeloid leukemia. As in allogeneic transplantation, veno-occlusive disease is an uncommon complication after an autograft using intravenous busulfan.

Internationalization strategy: Dom Pedro Hotel Group - São Paulo

A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

International Airlines Group: Equity Investment Report

A Work Project, presented as part of the requirements for the Award of a Masters Degree in Finance from the NOVA – School of Business and Economics