1000 resultados para Escore
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Enfermagem (mestrado profissional) - FMB
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Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Liver cirrhosis (LC) is a disease with high mortality rates and its only definitive treatment is the orthotopic liver transplantation (OLT). Unfortunately, not all patients have access to OLT and many of them end up dying on the transplant waiting list. The use of branched chain amino acids (BCAA) is widely known as an effective treatment for improving the quality of life of these patients. For the first time, in this paper we documented a great improvement of clinical and laboratorial tests of a patient treated with BCAA, which allowed him to be out of the transplant waiting list. In addition to the increase of the MELD score, the patient achieved restabilization of body weight and recovery of the quality of life registered by the SF-36 questionnaire.
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The real role of renal transplantation in hepatic fi brosis progression caused by hepatitis C virus is still unpredictable. Histological evaluation of the liver is the best form to estimate fi brosis evolution, although semiquantitative analysis carries important limitations. Objective: To apply a morphometric quantitative assay on hepatic fi brosis progression in renal recipients with hepatits C. Methods: Thirty patients were initially evaluated, but only seven were included. They underwent the fi rst biopsy near the transplantation date and the second biopsy at least 4 years later. The immunosuppressant therapy adopted in all cases was azatioprine and micofenolate. Fibrosis progression rate (FPR) was calculated before and after the surgery date in each patient according to Metavir score and morphometric analysis. Results: The FPR calculated by Metavir score showed no statistical difference between pre- and post-transplantation (p=0.9). The FPR calculated by the morphometric analysis was 0.58 ± 0.78 before transplantation and 3.0 ± 3.3 after the surgery, with statistical signi- fi cance between these values (p=0.0026). Conclusion: In the sample assessed, the progression of hepatic fi brosis was documented and quantifi ed only by the morphometric analysis, which is as a promising approach to histological evaluation of these patients.
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O objetivo deste estudo foi avaliar a evolução ponderal pós-gastrostomia em crianças com paralisia cerebral tipo tetra-plegia espástica. Mediante análise de variância para dados pareados, 33 crianças foram avaliadas nos momentos: 6 meses antes, à gastrostomia, 6 meses e 18-24 meses após. A mediana da idade à gastrostomia foi de 48,1 meses. 75,8% eram do gênero masculino. Houve ganho ponderal na comparação dos momentos: 6 meses antes, à gastrostomia e 6 meses após em relação a 18-24 meses após (p<0,001). Utilizando-se referencial específico de crescimento para paralisia cerebral, à gastrostomia e 18-24 meses após as crianças apresentavam percentil ≤10 (respectivamente, 52,4% e 33,3%) e >10 (respectivamente, 47,6% e 66,6%). As medianas do escore z do peso foram: 6 meses antes (-5,1), à gastrostomia (-5,0), 6 meses após (-4,7) e 18-24 meses após (-4,4), não havendo diferença significativa. Escore z ≤-2 foi observado em 75% das crianças 6 meses antes, 81,8% à gastrostomia, 75% 6 meses após e 64,5% 18-24 meses após. Na análise da mediana da idade, para as crianças com idade ≤ 48,1 meses não houve diferenças no escore z nos diferentes momentos. Para aquelas com idade >48,1 meses houve diferença significativa entre 6 meses antes e 18-24 meses após. Considerando as crianças mais (z≤-5,0) e menos (z>-5,0) comprometidas nutricionalmente, houve diferença significativa entre as mais comprometidas (p = 0,04) na comparação entre gastrostomia com 6 meses após e com 18-24 meses após. Este estudo demonstrou que 18-24 meses após a gastrostomia houve aumento ponderal para todas as crianças e aumento do escore z do peso naquelas com mais idade e mais comprometidas nutricionalmente.
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The sugarcane industry has been important in the Brazilian economy since the colonial period. The search for alternative energy sources has gained more prominence, by offering a product generating clean energy. With the opening of the Brazilian economy, the sector has undergone transformations operating in a free market environment requiring greater efficiency and competitiveness of those involved in order to stay in business. This scenario is producer/supplier independent, and social aspects related to their stay in the market. Although its share in sugarcane production is smaller than the plant itself, it is still considerable having reached around 20% to 25% in 2008 by employing labor, also production factors had an important economic impact in the regions where they operate. Therefore, this study aimed to estimate the economic efficiency and production of independent sugarcane producers in the state of Paraná through the DEA model. The Data envelopment analysis (DEA) is a nonparametric technique that, using linear programming constructs production borders from production units that employ similar technological processes to transform inputs into outputs.The results showed that of the total surveyed, 13.56% had maximum efficiency (an efficiency score equal to 1). The average efficiency under variable returns to scale (BCC-DEA) was 0.71024. One can thus conclude that for the majority of the samples collected, it might be better use of available resources to the in order to obtain the economic efficiency of the production process.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Enfermagem (mestrado profissional) - FMB
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Pós-graduação em Ciência e Tecnologia Animal - FEIS
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)