Avaliação e comparação do perfil de dissolução do Fluconazol 150mg cápsulas produto referência, genérico e similar

Fármacos com alta permeabilidade intestinal, ampla faixa terapêutica e ausência de evidências documentadas de bioinequivalência ou problemas de biodisponibilidade devido à formulação, foram considerados bioisentos pela ANVISA (RDC 37/2011), ou seja, os fármacos que se encaixam nesta categoria não necessitam de estudos de biodisponibilidade relativa/bioequivalência para serem comercializados. Dentre os catorze produtos que receberam a bioisenção da ANVISA, encontra-se o fluconazol, antifúngico aprovado atualmente para ser comercializado em vários países, inclusive no Brasil, onde inúmeras opções comerciais do produto fluconazol cápsulas, genérico ou similar, podem ser adquiridas. Tendo em vista a bioisenção do produto fluconazol cápsulas e sua larga utilização no mercado brasileiro, o estudo do perfil de dissolução deste produto torna-se relevante. Sendo assim, este trabalho avaliou 2 produtos genéricos e 2 produtos similares frente ao medicamento referência em relação aos seus perfis de dissolução e a similaridade entre eles. Os resultados foram avaliados seguindo a RDC 31/2011 da ANVISA que prevê o cálculo do fator de similaridade entre os perfis de dissolução. E, pôde-se observar que apenas 1 medicamento genérico apresentou o fator de similaridade adequado (entre 50 e 100), sendo 51,60, os demais medicamentos testes apresentaram valores fora do intervalo adotado pela ANVISA. Através desses resultados, conclui-se que intercambialidade do medicamento referência pelo medicamento genérico ou similar não é adequada, uma vez que eles não são considerados iguais, salvo um dos medicamentos genéricos.

Morfologia urbana na animação

The production and concept of the animation process adds not only technical aspects to it, but also the huge amount of detail and study of every single reference used to create that said animation. From costumes and fashion to urban morphology, those researches are needed for the creation of a final product that has a truth feeling to it, making the viewer feel like part of it and receive not only a literal aspect, but a conceptual feel from the project. Photos, maps, technical studies and much more are tools of trade when dealing with the animation process. The animators have to give attention to every single detail in order to make the production feel alive for the viewers, making the animations flow in a charming way. To analyse the inverse way of the animation process – from the final product to the sketch studies of the base reality from which it was based at- is a good way to comprehend the research line of the animators, and that’s the main focus of this project

Esportes de risco: perspectivas da psicologia do esporte na concepção do prazer

Com o ritmo acelerado que a vida moderna exige, é cada vez mais evidente a necessidade do ser humano em buscar novas experiências para que os façam sentir emoções e sensações inéditas, não existentes no dia a dia. Com isso a busca por esportes de risco vem sendo cada vez maior, visto que muitos destes esportes satisfazem os desejos por novas experiências. Acredita-se que haja inúmeros fatores atrativos que levam os indivíduos a aderirem a essas praticas. No presente estudo foi verificado que fatores psicológicos estão fortemente presentes, o medo e a ansiedade mostram-se fatores atrativos, assim como o desejo de conhecer lugares novos, o que aponta para uma ligação direta com o turismo. A sensação de bem estar, satisfação, alegria e orgulho foi afirmada por maioria dos sujeitos, o que acaba levando os indivíduos a procurarem diversos esportes de risco, favorecendo a aderência a essas modalidades e a permanência nas mesmas.

A concepção do aluno sobre o papel da educação física na escola após a experiência de acampante

Camping alloys the implementation of a broad variety of activities that involves many aspects of the corporal culture of movement. There is much more than fun in games and plays and that’s what we seek to include in the children’s daily routine. The Physical Education professional has as one of its duties to teach these elements, such as the knowledge related to the citizenship formation to its students. Therefore, the participation in camping can contribute to this formation, since the students have the chance to realize the amplitude of Physical Education and change their view on it, even at school. The aim of this research is to investigate after the camping experience, if the students change their conception on the Physical Education role at school. This study has used qualitative methodology consisting on interviews done prior and post the students camping experience at the school . Ten students of both gender, aged between 13 and 15 years old, were interviewed. It was used a script with semi-structured questions. As the main result it has found an unanimity among the students towards the importance of Physical Education: the responsibility for the health and it’s also arisen discussions on cooperation and respect. Although they recognize that the teacher does not discuss these values and attitudes; two students believe that to have changed their view towards school Physical Education after experiencing the activities proposed in the camping. Despite most of the students haven’t changed their concept on school Physical Education, they had the opportunity to see new activities and to think more carefully about the importance of Physical Education classes at school, an opportunity on building a more critical view on the discipline.

Estudo, desenvolvimento e concepção de uma célula de carga

In engineering projects, it’s fundamental to determine the active loads in components in order to guarantee acceptable values of safety and reliability according to project specifications. On the other hand, force measurement methods might be very complex and impracticable in some cases and, so that, load cells with eletric resistance strain gages can be applied as a simple and accurate option to measure the required load. The main purpose of this paper is to present the development of a load cell that measures uniaxial forces using electric resistance strain gages without being influenced by the location of the loading in a cantilever beam. For that, it was taken as basis a secondary purpose which is to present a general study of basic and wide concepts about transducers, load cells and extensometers primarily. Information such as: loading and measurements types, characteristics of the presented devices as well as factors that influence its functioning, the most common kinds of Wheatstone bridge links, the main points of a load cell project, cements used to fix extensometers and, finally, the project itself with the tests of the built transducer are presented. By the end of this paper, all the results are shown and analyzed, concluding about the designed load cell and the work itself

Parque Urbano – Arte e Educação Ambiental a partir de uma concepção lúdica

Não disponível

Basquetebol X temas transversais: a produção de material didático audiovisual para a Educação Física escolar

This study aimed, first, produce a kind of educational materials in audiovisual format, to the Physical Education, addressing the Transversal Themes in view of the basketball. The themes chosen were Cultural Plurality, addressing the basketball in a wheelchair, and Labor and Consumer Affairs, addressing the marketing and exploitation of labor force that the company is Nike. There is no doubt the importance of media production in contemporary society, as one of its main languages, but of little relevance in the school environment, especially in the area of Physical Education. In a second phase aimed at evaluating the feasibility of this material both as a teaching strategy, such as content of learning lessons. The evaluation was made through a discussion in the form of focus groups with 10 students from 9 th grade of elementary school. The results showed that despite an initial rejection of the material as a teaching strategy because of the history that Physical Education has for several years, students were open to new ways of learning. Since the results on the material, such as learning content, showed that the videos were able to address and the Transversal Themes and meet the need for procedural content with the proposed activities. With this, we realize that students are willing to discuss matters that are not always addressed, but now, with the creation of national curriculum standards should be reflected in the classroom

Concepção de um apart-hotel energicamente eficiente em São João da Boa Vista

A necessidade de se pensar o futuro, bem como a necessidade em atender uma demanda em questão, foram os pontos de partida deste trabalho, que aborda as questões teóricas e práticas do projeto de um Apart-hotel em São João da Boa Vista, utilizando técnicas de eficiência energética. Para alcançar o resultado final, foram abordadas questões como a utilização de cartas bioclimáticas, carta solar, entre outros fatores empregados para se entender e estudar as questões climáticas, bem como o estudo da cidade no que se refere à contextualização do projeto

Concepção e Implementação de um Sistema de Controle de Arborização Urbana através da Integração de Softwares Livres e de Código Aberto

Suitable computacional tools allow to build applications that can link information to its physical location, and represent them into visual and interactive schemes, e ectively reaching the power of visual comunication. This leads the user to synthesize information in a simple and e cient way. These applications are linked to the de nition of Geographic Information System (GIS). GIS are comprised by many concepts and tools, which have the main purpose of collecting, storing, viewing and processing spatial data, obtaining the information needed for decision making. Within this context, this paper presents the Conception and Implementation of a Control System for Urban Forestry through Integration of Free and Open Source Software. This conception arose from the need of an Environmental Project developed by the Agriculture's House of the city of Regente Feij o, which has as main objectives cataloging and management of urban a orestation of the municipality. Due to this diversity of concepts, the challenge in building this system is the integration of platforms that are involved in all stages: collecting and storage of data, including maps and other spatial information, operations on the stored information, obtaining results and graphical visualization of the same. After implementation, it was possible to provide for the system users an improvement in the capacity of perception in the information analysis and facilitate the process of decision making

Avaliação da taxa de concepção de novilhas e vacas (Bos taurus x Bos indicus) com o uso de sêmen sexado na inseminação artificial ou embriões produzidos in vivo e in vitro

Pós-graduação em Medicina Veterinária - FCAV

A democratização do ensino fundamental de 06 a 14 anos: que concepção de democracia tem sido adotada nas leis federais?

Pós-graduação em Educação - IBRC

A concepção de ferramentas de tradução como dinamizadoras da produção tradutória e seus reflexos para a prática

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A abordagem histórica do letramento: Ecos da memória na atualidade

The word literacy acquired a polysemy spectrum which put it away from the notion of social and historic process, at the same time that associates it to codification and decodification of writing. Concerning to this last perspective, we would have nothing to add. However, we sustain, in this paper, considering Pêcheux´s Discourse Analysis and Lacanian Psychoanalysis approaches, that there is a conception of literacy as a phenomenon which influences indirectly individuals and cultures for whom the competence of writing is not established. In this sense, the concept of literacy is larger than alphabetization. As an evidence of this proposal, we analyze a text written by a student, that demanded him to write about a context distant from his own, and, to do so, he mobilized places from the archive and from his particular memory, showing a singular knowledge of writing culture, even though his text presents interpenetration of oral an writing forms, aspect that is not allowed by those who defend an a-historical conception of literacy. We discuss that the student’s text ran away from the reduction of a merely pedagogic ideology and reflects a discursive coherence in face of the challenge that was proposed to him. By the end of this paper, we propose that the teachers should search for devices that make easier for their students to write texts in which their authorship could emerge.

Concepção(ões) de texto em contexto de EaD semipresencial

Conselho Nacional de Desenvolvimento em Pesquisa (CNPq)

Projeto e concepção de um quadcopter utilizando o controle PID

The present work refers to the design, conception and development of a quadcopter based on PID controllers, a widespread microcontroller on the market was being implemented, the Arduino. Also made use of LabVIEW programming tool from National Instruments company for the quadcopter control and telemetry. For the control, LabVIEW software acquired the joystick commands, making the necessary adjustments to the perfect interpretation by microcontroller on the quadcopter and adjusts the parameters of PID controllers. For telemetry, data relating to quadcopter behavior are received, interpreted and presented in an intuitive user interface. In the first part of this graduate work presents the theoretical background on the subject, with a brief history about the quadcopters, followed by the main projects in the academic and commercial matters. Also are presented the theories of communications used in the design and PID control. Then an overview of the dynamic and mathematical model is demonstrated. Having done this, the physical and computer components required to complete the project are showed and the results are achieved consequently. Finally, a conclusion is made taking into account the results obtained. In this work will be presented the PID control of quadcopter translational movements only to roll and pitch movements