Mal me quer, bem me quer: uma análise dos cuidados dispensados ao idoso asilar

This article aims to portray a survey in order to see whether the established in the Practical Guide Caregiver program (Ministry of Health, established in 2008 to improve the care for the elderly), are also affecting the nursing homes of smaller towns, with reference to a city in São Paulo State, with approximately 100,000 inhabitants located in western Sao Paulo State.

Bem-me-quer, malmequer: uma análise dos cuidados dispensados ao idoso asilar

This article aims to portray a survey in order to see whether the established in the Practical Guide Caregiver program (Ministry of Health, established in 2008 to improve the care for the elderly), are also affecting the nursing homes of smaller towns, with reference to a city in São Paulo State, with approximately 100,000 inhabitants located in western Sao Paulo State.

O teatro do oprimido como ferramenta educativa: ações junto aos adolescentes em estado de vulnerabilidade social

This article is a theoretical and practical portrait of a non-formal educational activities aimed to examine the transformations experienced by young people in a state of social vulnerability participating in social discussions in a form of theater of the oppressed - the theater-forum. The technique of theater-forum was held as a methodology able to establish a critical space action / reflection / action on the social reality experienced by these young people. The discussions postulates in some theatrical performances were analyzed critically and scored from theoretical frameworks of contemporary thinkers (Bauman, Augé, Boal,Bock, Aguiar, Ozella). We conclude that this action re-signified social problems (violence, drug involvement, hyperconsumerism, poverty, cultural capital etc.) Among these young people. In general, the young through a collective construction could experience new processes of subjectivity and open to possible changes and social transformations criticism in your life.

O teatro do oprimido como ferramenta psicoeducativa

This article is a theoretical and practical portrait of a non-formal educational activities aimed to examine the transformations experienced by young people in a state of social vulnerability participating in social discussions in a form of theater of the oppressed - the theater-forum. The technique of theater-forum was held as a methodology able to establish a critical space action / reflection / action on the social reality experienced by these young people. The discussions postulates in some theatrical performances were analyzed critically and scored from theoretical frameworks of contemporary thinkers (Bauman, Augé, Boal) and analysts sociohistorical (Bock, Aguiar, Ozella). We conclude that this action re-signified social problems (violence, drug involvement, hyper-consumerism, poverty, cultural capital etc.) among these young people. In general, the young through a collective construction could experience new processes of subjectivity and open to possible changes and social transformations criticism in your life.

A escola na condição de não lugar

This article portrays the changes that schools and education have been undergoing since the Middle Ages to the contemporary era. Its main focus points at the subjective issues that underlie the school as educational space necessary for the maintenance of society. It ends by showing that the school currently is losing its historical, relational and identity function (essential issues to structure a society) and is becoming a non place (concept of Marc Augé), into an institution without apparent social function, held only as a still a consumable and profitable commodity.

Uma breve análise da historiografia da educação brasileira

O presente artigo teórico procura analisar a educação brasileira enquanto elemento histórico e que hoje se encontra no dilema em seguir uma tendência nacional ou se submeter às regras do mundo globalizado. Para tanto, fazemos uma análise do surgimento da educação na era medieval, pré-moderna, moderna e contemporânea. Por fim questionamos se a educação é ainda uma instituição valorizada ou perdeu seu lugar, tornando-se um espaço desvirtuado.

Comportamentos de coping no contexto da hospitalização infantil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

As festas escolares no Brasil: uma análise a partir da literatura sobre a temática e à luz da teoria crítica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Diabetes reduces mesenchymal stem cells in fracture healing through a TNF alpha-mediated mechanism

Diabetes interferes with bone formation and impairs fracture healing, an important complication in humans and animal models. The aim of this study was to examine the impact of diabetes on mesenchymal stem cells (MSCs) during fracture repair.Fracture of the long bones was induced in a streptozotocin-induced type 1 diabetic mouse model with or without insulin or a specific TNF alpha inhibitor, pegsunercept. MSCs were detected with cluster designation-271 (also known as p75 neurotrophin receptor) or stem cell antigen-1 (Sca-1) antibodies in areas of new endochondral bone formation in the calluses. MSC apoptosis was measured by TUNEL assay and proliferation was measured by Ki67 antibody. In vitro apoptosis and proliferation were examined in C3H10T1/2 and human-bone-marrow-derived MSCs following transfection with FOXO1 small interfering (si)RNA.Diabetes significantly increased TNF alpha levels and reduced MSC numbers in new bone area. MSC numbers were restored to normal levels with insulin or pegsunercept treatment. Inhibition of TNF alpha significantly reduced MSC loss by increasing MSC proliferation and decreasing MSC apoptosis in diabetic animals, but had no effect on MSCs in normoglycaemic animals. In vitro experiments established that TNF alpha alone was sufficient to induce apoptosis and inhibit proliferation of MSCs. Furthermore, silencing forkhead box protein O1 (FOXO1) prevented TNF alpha-induced MSC apoptosis and reduced proliferation by regulating apoptotic and cell cycle genes.Diabetes-enhanced TNF alpha significantly reduced MSC numbers in new bone areas during fracture healing. Mechanistically, diabetes-enhanced TNF alpha reduced MSC proliferation and increased MSC apoptosis. Reducing the activity of TNF alpha in vivo may help to preserve endogenous MSCs and maximise regenerative potential in diabetic patients.

Adsorption of immunoglobulin Y in supermacroporous continuous cryogel with immobilized Cu2+ ions

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

First report of the characterization of the pathophysiological mechanisms caused by the freshwater catfish Pimelodus maculatus (order: Siluriformes)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Clopidogrel enhances mesenchymal stem cell proliferation following periodontitis

Bone formation is dependent on the differentiation of osteoblasts from mesenchymal stem cells (MSCs). In addition to serving as progenitors, MSCs reduce inflammation and produce factors that stimulate tissue formation. Upon injury, MSCs migrate to the periodontium, where they contribute to regeneration. We examined the effect of clopidogrel and aspirin on MSCs following induction of periodontitis in rats by placement of ligatures. We showed that after the removal of ligatures, which induces resolution of periodontal inflammation, clopidogrel had a significant effect on reducing the inflammatory infiltrate. It also increased the number of osteoblasts and MSCs. Mechanistically, the latter was linked to increased proliferation of MSCs in vivo and in vitro. When given prior to inducing periodontitis, clopidogrel had little effect on MSC or osteoblasts numbers. Applying aspirin before or after induction of periodontitis did not have a significant effect on the parameters measured. These results suggest that clopidogrel may have a positive effect on MSCs in conditions where a reparative process has been initiated.

Androgen receptors and experimental bone loss - an in vivo and in vitro study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The long-term administration of calcineurin inhibitors decreases antioxidant enzyme activity in the rat parotid and submandibular salivary glands

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)