Productive performance and parasitological control of kids supplemented with umbu fruits (Spondias tuberosa Arruda).

Native fruits from Caatinga vegetation can be an important alternative to improve the productive performance of kids in the semi-arid region of Brazil. This work aimed to evaluate the effect of supplementation with Umbuzeiro fruits in natura over the weight gain and anthelmintic control of kids kept in Buffel grass pasture in the semi-arid zone of Pernambuco, Brazil. Twenty-four castrated, crossbreed kids were allocated into three treatments: 1) Control (n = 8) fed exclusively with Buffel grass; 2) Umbu 1x (n = 8) fed with fruits once a week and 3) Umbu 3x (n = 8) fed with fruits for three times a week. The following parameters were evaluated: variation of body weight, faecal egg counts (FEC) and coproculture. Overall, the average consumption of Umbu fruits in natura was 1.48 kg/animal/day, which corresponded to 133.5 g daily dry matter intake (DMI/animal/day). There were no significant difference (P>0.05) for any parameters evaluated. During the experimental period, the overall daily weight gain was variable between 108.75 to 116.70 g/animal/day and the average FEC was 436 eggs. In the present study, the goat kids supplemented with fresh umbu fruits showed a good productive performance, however the supplementation with umbu did not control the infestation of gastrointestinal nematodes in kids.

Desenvolvimento dos ácidos orgânicos em diferentes fases fenológicas de uvas viníferas destinadas à elaboração de vinhos tintos tropicais no Brasil.

A Região do Vale do São Francisco possui condições privilegiadas para o cultivo das videiras, tais como baixa precipitação pluviométrica e disponibilidade de água para irrigação que possibilitam um estresse hídrico e ciclo vegetativo da videira controlados pelo viticultor, permitindo a produção escalonada durante a maior parte do ano (LIMA, 2010) As uvas viníferas contêm na casca, polpa e sementes, uma grande quantidade de diferentes compostos considerados essenciais à qualidade e tipicidade dos vinhos. Se destacam: os açúcares, transformados em álcool durante a sua elaboração; os compostos nitrogenados utilizados pelas leveduras como fonte de energia para a transformação dos açúcares em álcool; os precursores de aromas revelados pelas enzimas das leveduras na vinificação; os ácidos orgânicos com importante papel na conservação e equilíbrio e os compostos fenólicos responsáveis pela coloração e estrutura de vinhos tintos (SILVA NETO et al., 2009). De acordo com Mandelli et al. (2003) a qualidade do vinho encontra-se diretamente relacionada à composição química e ao ponto ideal de colheita da uva, evento que envolve maturações fisiológica, tecnológica e fenólica. Embora as condições edafoclimáticas, os tratos culturais e manejo dos vinhedos tenham fundamental importância sobre os estádios de desenvolvimento das bagas, as pesquisas sobre o tema, nas condições climáticas desta Região são ainda incipientes. Este estudo teve como objetivo avaliar a evolução dos ácidos orgânicos de variedades de uvas viníferas tintas destinadas a produção de vinhos finos no Vale do São Francisco (VSF).

A LITTLE HISTORY OF LINGUISTIC IN BRAZIL: INTERVIEW WITH JOSÉ BORGES NETO

We are pleased to present this edition of the journal Language & Letters, interview courtesy Professor José Borges Neto, researcher recognized for the excellent work that develops in Linguistics with an emphasis in Philosophy of Language. Professor holds a degree in Literature from the Pontifical Catholic University of Paraná (1972), MA in Linguistics from the State University of Campinas (1979) and PhD in Linguistics from the State University of Campinas (1991). Professor of the Federal University of Paraná between 1999 and 2010. Retired in 2010, continues to serve as Senior Lecturer in the Graduate Program in Linguistics UFPR and a senior professor at Unioeste in the period 2012-2016. Has experience in the area of ​​linguistics, with an emphasis on semantics, acting on the following topics: Epistemology of Linguistics, Linguistics Historiography, Formal Semantics and Categorial Grammars.

CARTOGRAFIAS DA ESPANHA NA LÍRICA DE JOÃO CABRAL DE MELO NETO

As referências culturais à Espanha estão presentes na lírica de João Cabral de Melo Neto desde Pedra do sono (1942); como consequência, a geografia espanhola surge em vários poemas ao longo de sua produção literária. No ano de 1990, o poeta expressa sua preferência pela região de Andaluzia ao publicar Sevilha Andando e Andando Sevilha. Nesta obra, o eu-lírico apresenta uma cidade marcada por uma essência sensual e feminina, onde o espaço materializa-se na forma da mulher sevilhana. Não obstante, a obra revela também uma Sevilha percorrida pelo próprio eu-lírico, recuperando a cartografia da cidade em seus bairros tradicionais, em seus traços geométricos por meio da descrição de sua arquitetura, da riqueza do cotidiano e dos tipos andaluzes. Este artigo tem por objetivo examinar como o território espanhol, representado no poema A sevilhana que não se sabia, do livro em questão, constitui-se em espaço de relações interculturais entre Brasil e Espanha, através do olhar que o poeta lança à cultura do Outro.

Gretel and Edith: Jewish woman and exile in Alves Redol and in Joaquim Paço d’Arcos

Abstract: This paper examines the narrative construction of Jewish women in the short novel “O Mundo Perdido”, by Joaquim Paço d’Arcos, and in the short story “Nasci com Passaporte de Turista”, by Alves Redol.  Both narratives portray the rise of Nazism in Germany in the 1930s and its effects.  Historical, biographical and literary information is taken into consideration to the analysis.

Novel educational training program for community pharmacists

There is little evidence that workshops alone have a lasting impact on the day-to-day practice of participants. The current paper examined a strategy to increase generalization and maintenance of skills in the natural environment using pseudo-patients and immediate performance feedback to reinforce skills acquisition. A random half of pharmacies (N=30) took part in workshop training aimed at optimizing consumers' use of nonprescription analgesic products. Pharmacies in the training group also received performance feedback on their adherence to the recommended protocol. Feedback occurred immediately after a pseudo-patient visit in which confederates posed as purchasers of analgesics, and combined positive and corrective elements. Trained pharmacists were significantly more accurate at identifying people who misused the medication (P<0.001). The trained pharmacists were more likely than controls to use open-ended questions (P<0.001), assess readiness to change problematic use (P <0.001), and to deliver a brief intervention that was tailored to the person's commitment to alter his/her usage (P <0.001). Participants responded to the feedback positively. Results were consistent with the hypothesis that when workshop is combined with on-site performance feedback, it enhances practitioners' adherence to protocols in the natural setting.

Interactions between energy intake and expenditure in the development and treatment of obesity.

Summary There are four interactions to consider between energy intake (EI) and energy expenditure (EE) in the development and treatment of obesity. (1) Does sedentariness alter levels of EI or subsequent EE? and (2) Do high levels of EI alter physical activity or exercise? (3) Do exercise-induced increases in EE drive EI upwards and undermine dietary approaches to weight management and (4) Do low levels of EI elevate or decrease EE? There is little evidence that sedentariness alters levels of EI. This lack of cross-talk between altered EE and EI appears to promote a positive EB. Lifestyle studies also suggest that a sedentary routine actually offers the opportunity for over-consumption. Substantive changes in non exercise activity thermogenesis are feasible, but not clearly demonstrated. Cross talk between elevated EE and EI is initially too weak and takes too long to activate, to seriously threaten dietary approaches to weight management. It appears that substantial fat loss is possible before intake begins to track a sustained elevation of EE. There is more evidence that low levels of EI does lower physical activity levels, in relatively lean men under conditions of acute or prolonged semi-starvation and in dieting obese subjects. During altered EB there are a number of small but significant changes in the components of EE, including (i) sleeping and basal metabolic rate, (ii) energy cost of weight change alters as weight is gained or lost, (iii) exercise efficiency, (iv) energy cost of weight bearing activities, (v) during substantive overfeeding diet composition (fat versus carbohydrate) will influence the energy cost of nutrient storage by ~ 15%. The responses (i-v) above are all “obligatory” responses. Altered EB can also stimulate facultative behavioural responses, as a consequence of cross-talk between EI and EE. Altered EB will lead to changes in the mode duration and intensity of physical activities. Feeding behaviour can also change. The degree of inter-individual variability in these responses will define the scope within which various mechanisms of EB compensation can operate. The relative importance of “obligatory” versus facultative, behavioural responses -as components of EB control- need to be defined.

Thinking spatially, acting collaboratively : a GIS-based health decision support system for improving the collaborative health-planning practice

The field of collaborative health planning faces significant challenges due to the lack of effective information, systems and the absence of a framework to make informed decisions. These challenges have been magnified by the rise of the healthy cities movement, consequently, there have been more frequent calls for localised, collaborative and evidence-driven decision-making. Some studies in the past have reported that the use of decision support systems (DSS) for planning healthy cities may lead to: increase collaboration between stakeholders and the general public, improve the accuracy and quality of the decision-making processes and improve the availability of data and information for health decision-makers. These links have not yet been fully tested and only a handful of studies have evaluated the impact of DSS on stakeholders, policy-makers and health planners. This study suggests a framework for developing healthy cities and introduces an online Geographic Information Systems (GIS)-based DSS for improving the collaborative health planning. It also presents preliminary findings of an ongoing case study conducted in the Logan-Beaudesert region of Queensland, Australia. These findings highlight the perceptions of decision-making prior to the implementation of the DSS intervention. Further, the findings help us to understand the potential role of the DSS to improve collaborative health planning practice.

Ontologies derived from Wikipedia : a framework for comparison

Since its debut in 2001 Wikipedia has attracted the attention of many researchers in different fields. In recent years researchers in the area of ontology learning have realised the huge potential of Wikipedia as a source of semi-structured knowledge and several systems have used it as their main source of knowledge. However, the techniques used to extract semantic information vary greatly, as do the resulting ontologies. This paper introduces a framework to compare ontology learning systems that use Wikipedia as their main source of knowledge. Six prominent systems are compared and contrasted using the framework.

Structures of life : the role of molecular structures in scientists' work

The visual and multidimensional representations like images and graphical structures related to biology provide great insights into understanding the complexities of different organisms. Especially, life scientists use different representations of molecular structures to answer biological questions and to better understand cellular processes. Combining results from two field studies, we explore the role of molecular structures in life scientists’ current work from a humanfactors perspective. Our main conclusion is that different representations of molecular structures, due to their visual nature, are important for supporting collaboration, constructing new knowledge and supporting scientists’ professional activities in general.

Privacy enhancements for hardware-based security modules

The increasing growth in the use of Hardware Security Modules (HSMs) towards identification and authentication of a security endpoint have raised numerous privacy and security concerns. HSMs have the ability to tie a system or an object, along with its users to the physical world. However, this enables tracking of the user and/or an object associated with the HSM. Current systems do not adequately address the privacy needs and as such are susceptible to various attacks. In this work, we analyse various security and privacy concerns that arise when deploying such hardware security modules and propose a system that allow users to create pseudonyms from a trusted master public-secret key pair. The proposed system is based on the intractability of factoring and finding square roots of a quadratic residue modulo a composite number, where the composite number is a product of two large primes. Along with the standard notion of protecting privacy of an user, the proposed system offers colligation between seemingly independent pseudonyms. This new property when combined with HSMs that store the master secret key is extremely beneficial to a user, as it offers a convenient way to generate a large number of pseudonyms using relatively small storage requirements.

Reactive reaching and grasping on a humanoid: Towards closing the action-perception loop on the iCub

We propose a system incorporating a tight integration between computer vision and robot control modules on a complex, high-DOF humanoid robot. Its functionality is showcased by having our iCub humanoid robot pick-up objects from a table in front of it. An important feature is that the system can avoid obstacles - other objects detected in the visual stream - while reaching for the intended target object. Our integration also allows for non-static environments, i.e. the reaching is adapted on-the-fly from the visual feedback received, e.g. when an obstacle is moved into the trajectory. Furthermore we show that this system can be used both in autonomous and tele-operation scenarios.

Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population

Objective: Association between ankylosing spondylitis (AS) and two genes, ERAP1 and IL23R, has recently been reported in North American and British populations. The population attributable risk fraction for ERAP1 in this study was 25%, and for IL23R, 9%. Confirmation of these findings to ERAP1 in other ethnic groups has not yet been demonstrated. We sought to test the association between single nucleotide polymorphisms (SNPs) in these genes and susceptibility to AS among a Portuguese population. We also investigated the role of these genes in clinical manifestations of AS, including age of symptom onset, the Bath Ankylosing Spondylitis Disease Activity, Metrology and Functional Indices, and the modified Stoke Ankylosing Spondylitis Spinal Score. Methods: The study was conducted on 358 AS cases and 285 ethnically matched Portuguese healthy controls. AS was defined according to the modified New York Criteria. Genotyping of IL23R and ERAP1 allelic variants was carried out with TaqMan allelic discrimination assays. Association analysis was performed using the Cochrane-Armitage and linear regression tests of genotypes as implemented in PLINK for dichotomous and quantitative variables respectively. A meta-analysis for Portuguese and previously published Spanish IL23R data was performed using the StatsDirect® Statistical tools, by fixed and random effects models. Results: A total of 14 nsSNPs markers (8 for IL23R, 5 for ERAPl, 1 for LN-PEP) were analysed. Three markers (2 for IL23R and 1 for ERAP1) showed significant single-locus disease associations, confirming that the association of these genes with AS in the Portuguese population. The strongest associated SNP in IL23R was rs1004819 (OR=1.4, p=0.0049), and in ERAP1 was rs30187 (OR=1.26, p=0.035). The population attributable risk fractions in the Portuguese population for these SNPs are 11% and 9.7% respectively. No association was seen with any SNP in LN-PEP, which flanks ERAP1 and was associated with AS in the British population. No association was seen with clinical manifestations of AS. Conclusions: These results show that IL23R and ERAP1 genes are also associated with susceptibility to AS in the Portuguese population, and that they contribute a significant proportion of the population risk for this disease.

Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts

The availability of population-specific normative data regarding disease severity measures is essential for patient assessment. The goals of the current study were to characterize the pattern of ankylosing spondylitis (AS) in Portuguese patients and to develop reference centile charts for BASDAI, BASFI, BASMI and mSASSS, the most widely used assessment tools in AS. AS cases were recruited from hospital outpatient clinics, with AS defined according to the modified New York criteria. Demographic and clinical data were recorded. All radiographs were evaluated by two independent experienced readers. Centile charts for BASDAI, BASFI, BASMI and mSASSS were constructed for both genders, using generalized linear models and regression models with duration of disease as independent variable. A total of 369 patients (62.3% male, mean ± (SD) age 45.4 ± 13.2 years, mean ± (SD) disease duration 11.4 ± 10.5 years, 70.7% B27-positive) were included. Family history of AS in a first-degree relative was reported in 17.6% of the cases. Regarding clinical disease pattern, at the time of assessment 42.3% had axial disease, 2.4% peripheral disease, 40.9% mixed disease and 7.1% isolated enthesopatic disease. Anterior uveitis (33.6%) was the most common extra-articular manifestation. The centile charts suggest that females reported greater disease activity and more functional impairment than males but had lower BASMI and mSASSS scores. Data collected through this study provided a demographic and clinical profile of patients with AS in Portugal. The development of centile charts constitutes a useful tool to assess the change of disease pattern over time and in response to therapeutic interventions.