904 resultados para GST and incapacitated entities


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Part 8: Business Strategies Alignment

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Mestrado em Economia e Gestão de Ciência, Tecnologia e Inovação

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Aquatic plants of the genus Ruppia inhabit some of the most threatened habitats in the world, such as coastal lagoons and inland saline to brackish waters where their meadows play several key roles. The evolutionary history of this genus has been affected by the processes of hybridization, polyploidization, and vicariance, which have resulted in uncertainty regarding the number of species. In the present study, we apply microsatellite markers for the identification, genetic characterization, and detection of hybridization events among populations of putative Ruppia species found in the southern Iberian Peninsula, with the exception of a clearly distinct species, the diploid Ruppia maritima. Microsatellite markers group the populations into genetically distinct entities that are not coincident with geographical location and contain unique diagnostic alleles. These results support the interpretation of these entities as distinct species: designated here as (1) Ruppia drepanensis, (2) Ruppia cf. maritima, and (3) Ruppia cirrhosa. A fourth distinct genetic entity was identified as a putative hybrid between R. cf. maritima and R. cirrhosa because it contained a mixture of microsatellite alleles that are otherwise unique to these putative species. Hence, our analyses were able to discriminate among different genetic entities of Ruppia and, by adding multilocus nuclear markers, we confirm hybridization as an important process of speciation within the genus. In addition, careful taxonomic curation of the samples enabled us to determine the genotypic and genetic diversity and differentiation among populations of each putative Ruppia species. This will be important for identifying diversity hotspots and evaluating patterns of population genetic connectivity. © 2015 The Linnean Society of London, Biological Journal of the Linnean Society, 2015, 00, 000–000.

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Purpose: To investigate the effect of ampicillin on rat intestinal microflora and liver in the presence of high carbohydrate and protein diets. Methods: Male Wistar albino rats were divided into four groups. The first group served as the control, the second group was treated with ampicillin (50 mg/kg for 3 weeks) and fed with a standard diet, while the third and fourth groups were treated with the same dose of ampicillin and fed with acarbohydrateand protein-rich diets, respectively, to observe the effect of diet on gut flora and liver. Fecal specimens were collected and used for qualitative determination of gut microbiota composition. Serum hepatospecific markers (AST, ALT and ALP) were estimated. The antioxidant status of liver tissues was estimated for GSH, MDA, GST, LDH and vitamin C l, in addition to sodium and potassium. Results: Administration of orogastric dose of ampicillin for 3 weeks induced inhibition of E.coli, yeasts, total anaerobes, and anaerobic lactobacilli with new growth of P. vulgaris and K. pneumonia. The levels of serum AST, ALT and ALP showed significant (p ˂ 0.05) increase to 163, 112.38 and 115.35 %, respectively in ampicillin-treated animals, compared to control. Also significant (p ˂ 0.05) increase in lipid peroxidation (120 %) and LDH (111 %) coupled with significant (p ˂ 0.05) decrease in glutathione (74.57 %), vitamin C (63.49 %) and glutathione S-transferase (41.51 %) were observed in ampicillintreated groups. No significant variation (p ˂ 0.05) in sodium and potassium levels were found between control and the treated group after 3 weeks of treatment. Conclusion: These results confirm that extended ampicillin therapy disrupts gut flora, which results in liver injury; hence, overuse of antibiotics should be avoid.

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Presence of monitors in physical activities and sports practiced by adults older than 64 years of age in Spain is analyzed in this research. The objective of this study is to determine the existence of monitors in relation to the sociodemographic features of older adults, the size of municipalities, the activities practiced, and the organizations where they are performed. The methodology used included a cross-sectional survey applied to a sample of older adults in Spain. The most relevant conclusions are that the presence of monitors in physical activities and sports practiced by older adults is dominant (63.8%), hence, their importance, and that the presence of monitors is higher for women (81.3%) than for men (37.5%). In addition, it is concluded that the bigger the municipality the higher the tendency to have more instructors. Regarding the type of activity, wide diversification is obtained; finally, there is a larger presence of monitors in sports entities (87.5%) and nursing homes (79.5%).

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Sports and recreation management is addressed here using a model that combines the policies and methodologies applied in the Costa Rican context as a result of a concern to identify the real needs in the sports, recreation, and health promotion fields through the different manifestations of human movement.  This approach has been developed during eight years of work in the Costa Rican Sports and Recreation Institute (Instituto Costarricense del Deporte y la Recreación-ICODER) together with different Costa Rican communities, both rural and urban, and local organizations, such as Comprehensive Development Community Associations, Sports and Recreation Community Boards (CCDR), Municipal Mayorships, and NGOs, among others.  This article particularly takes into consideration the experience of the CCDRs as entities that have been given the responsibility by the Costa Rican Government to promote and manage municipal sports and recreation services with a convenient offering that would meet the needs of users or customers.  In this way, this article is aimed at answering the question on how Boards should conduct an efficient management in a way that they also meet the needs of public users or customers in the municipalities of the country, by proposing a management model that serves as an additional instrument to improving the already existing services managed by the aforementioned entities.  This study presents a model of Costa Rican management structured with the theoretical elements that currently define the organization and planning of sports and recreation as a service.

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One major difficulty confronting attempts to clarify the epistemological and ontological status of abstract objects is determining the sense, if any, in which such entities may be characterised as mind and language independent. Our contention is that the tolerant reductionist position of Michael Dummett can be strengthened by drawing on Husserl's mature account of the constitution of ideal objects and mathematical objectivity. According to the Husserlian position we advocate, abstract singular terms pick out weakly mind-independent sedimented meaning-contents. These meaning-contents serve as the 'thin' referents of abstract singular terms, but are ultimately founded in prior acts of meaning-constitution.

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The purpose of this article is to explore the GST implications of small-scale property development in Australia and to provide guidance as to whether such activities give rise to a GST liability. The legislation governing the operation of the GST affecting these projects uses the familiar termi- nology of ‘business’, but it also uses terminology such as ‘adventure or concern in the nature of trade’, which has not received extensive consid- eration by the Australian courts. The authors review relevant case law to identify key principles, which will guide the courts in applying this termi- nology to small-scale property development, and provide guidance as to when a taxpayer undertaking such projects will be required to register for GST. The authors also discuss the factors relevant to determining the impact of the timing of registration. The article concludes that small-scale property developers need to be aware of the complexities and uncertainty in relation to the application of the GST to such projects.

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Event detection on Twitter has become a promising research direction due to Twitter's popularity, up-to-date feature, free writing style and so on. Unfortunately, it's a challenge to analyze Twitter dataset for event detection, since the informal expressions of short messages comprise many abbreviations, Internet buzzwords, spelling mistakes, meaningless contents etc. Previous techniques proposed for Twitter event detection mainly focus on clustering bursty words related to the events, while ignoring that these words may not be easily interpreted to clear event descriptions. In this paper, we propose a General and Event-related Aspects Model (GEAM), a new topic model for event detection from Twitter that associates General topics and Event-related Aspects with events. We then introduce a collapsed Gibbs sampling algorithm to estimate the word distributions of General topics and Event-related Aspects in GEAM. Our experiments based on over 7 million tweets demonstrate that GEAM outperforms the state-of-the-art topic model in terms of both Precision and DERate (measuring Duplicated Events Rate detected). Particularly, GEAM can get better event representation by providing a 4-tuple (Time, Locations, Entities, Keywords) structure of the detected events. We show that GEAM not only can be used to effectively detect events but also can be used to analyze event trends. © 2013 Springer-Verlag.

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In concert with AIATSIS’ Guidelines for Ethical Research in Australian Indigenous Studies 2012, these guidelines articulate the need for the researcher to position their own research from the outset, before any research takes place. The rationale of these guidelines are to protect the rights for Indigenous peoples whilst building a strong relational connection with participants of the research. Pre-‐ethic guidelines are necessary in order to bring to the foreground Indigenous knowledges and relationships premised on the needs, rights and aspirations of Indigenous peoples, communities and entities.

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With wireless vehicular communications, Vehicular Ad Hoc Networks (VANETs) enable numerous applications to enhance traffic safety, traffic efficiency, and driving experience. However, VANETs also impose severe security and privacy challenges which need to be thoroughly investigated. In this dissertation, we enhance the security, privacy, and applications of VANETs, by 1) designing application-driven security and privacy solutions for VANETs, and 2) designing appealing VANET applications with proper security and privacy assurance. First, the security and privacy challenges of VANETs with most application significance are identified and thoroughly investigated. With both theoretical novelty and realistic considerations, these security and privacy schemes are especially appealing to VANETs. Specifically, multi-hop communications in VANETs suffer from packet dropping, packet tampering, and communication failures which have not been satisfyingly tackled in literature. Thus, a lightweight reliable and faithful data packet relaying framework (LEAPER) is proposed to ensure reliable and trustworthy multi-hop communications by enhancing the cooperation of neighboring nodes. Message verification, including both content and signature verification, generally is computation-extensive and incurs severe scalability issues to each node. The resource-aware message verification (RAMV) scheme is proposed to ensure resource-aware, secure, and application-friendly message verification in VANETs. On the other hand, to make VANETs acceptable to the privacy-sensitive users, the identity and location privacy of each node should be properly protected. To this end, a joint privacy and reputation assurance (JPRA) scheme is proposed to synergistically support privacy protection and reputation management by reconciling their inherent conflicting requirements. Besides, the privacy implications of short-time certificates are thoroughly investigated in a short-time certificates-based privacy protection (STCP2) scheme, to make privacy protection in VANETs feasible with short-time certificates. Secondly, three novel solutions, namely VANET-based ambient ad dissemination (VAAD), general-purpose automatic survey (GPAS), and VehicleView, are proposed to support the appealing value-added applications based on VANETs. These solutions all follow practical application models, and an incentive-centered architecture is proposed for each solution to balance the conflicting requirements of the involved entities. Besides, the critical security and privacy challenges of these applications are investigated and addressed with novel solutions. Thus, with proper security and privacy assurance, these solutions show great application significance and economic potentials to VANETs. Thus, by enhancing the security, privacy, and applications of VANETs, this dissertation fills the gap between the existing theoretic research and the realistic implementation of VANETs, facilitating the realistic deployment of VANETs.

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Event extraction from texts aims to detect structured information such as what has happened, to whom, where and when. Event extraction and visualization are typically considered as two different tasks. In this paper, we propose a novel approach based on probabilistic modelling to jointly extract and visualize events from tweets where both tasks benefit from each other. We model each event as a joint distribution over named entities, a date, a location and event-related keywords. Moreover, both tweets and event instances are associated with coordinates in the visualization space. The manifold assumption that the intrinsic geometry of tweets is a low-rank, non-linear manifold within the high-dimensional space is incorporated into the learning framework using a regularization. Experimental results show that the proposed approach can effectively deal with both event extraction and visualization and performs remarkably better than both the state-of-the-art event extraction method and a pipeline approach for event extraction and visualization.

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Antimicrobial resistance is a major health problem. After decades of research, numerous difficulties in tackling resistance have emerged, from the paucity of new antimicrobials to the inefficient contingency plans to reduce the use of antimicrobials; consequently, resistance to these drugs is out of control. Today we know that bacteria from the environment are often at the very origin of the acquired resistance determinants found in hospitals worldwide. Here we define the genetic components that flow from the environment to pathogenic bacteria and thereby confer a quantum increase in resistance levels, as resistance units (RU). Environmental bacteria as well as microbiomes from humans, animals, and food represent an infinite reservoir of RU, which are based on genes that have had, or not, a resistance function in their original bacterial hosts. This brief review presents our current knowledge of antimicrobial resistance and its consequences, with special focus on the importance of an ecologic perspective of antimicrobial resistance. This discipline encompasses the study of the relationships of entities and events in the framework of curing and preventing disease, a definition that takes into account both microbial ecology and antimicrobial resistance. Understanding the flux of RU throughout the diverse ecosystems is crucial to assess, prevent and eventually predict emerging scaffolds before they colonize health institutions. Collaborative horizontal research scenarios should be envisaged and involve all actors working with humans, animals, food and the environment.

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Social identity poses one of the most important challenges to rational choice theory, but rational choice theorists do not hold a common position regarding identity. On one hand, externalist rational choice ignores the concept of identity or reduces it to revealed preferences. On the other hand, internalist rational choice considers identity as a key concept in explaining social action because it permits expressive motivations to be included in the models. However, internalist theorists tend to reduce identity to desire—the desire of a person to express his or her social being. From an internalist point of view, that is, from a viewpoint in which not only desires but also beliefs play a key role in social explanations as mental entities, this article rejects externalist reductionism and proposes a redefinition of social identity as a net of beliefs about oneself, beliefs that are indexical, robust, and socially shaped.

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The recent development of the concept of microgrid (μGrid), associated to the emergent interest in microgeneration (μGen), has raised a number of challenges regarding the evaluation of the technical, economical and regulatory impacts of a high penetration of this kind of solutions in the power systems. In this paper, the topic of security of supply is addressed, aiming at evaluating the influence of μGen and μGrids in the medium- and long-term availability of generation to serve the forecasted load. A Monte-Carlo based methodology is used to evaluate this influence and to assess the capacity credit of those entities.