311 resultados para fêmur
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Programa de doctorado: Avances en Traumatología. Medicina del Deporte. Cuidado de heridas (Interdepartamental)
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Programa de doctorado: Avances en Traumatología.
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Mode of access: Internet.
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O Brasil está em nítido processo de envelhecimento. Tendo em vista as perspectivas de aumento da população idosa e as transformações epidemiológicas inerentes a estas mudanças, faz-se necessário um maior investimento em políticas e ações de saúde direcionadas ao público idoso. A fratura de fêmur consiste em uma importante causa de morbimortalidade para esta faixa etária no Brasil. Diante disso, este trabalho propõe um plano de ações que objetiva a prevenção de quedas e da fratura de fêmur em idosos através de medidas que permeiam o contexto sócio-economico-cultural do idoso e tem como atores envolvidos nas ações a Equipe de Saúde da Família, a comunidade, a família, os cuidadores e o próprio idoso. A metodologia utilizada na construção do Plano de Ações foi a do Planejamento Estratégico Situacional.
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Esse seminário aborda os cuidados que devem ser realizados ao individuo com fratura de fêmur, tipos de cobertura, período de reabilitação e recuperação.
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OBJECTIVE: To analyze if female Wistar rats at 56 weeks of age are a suitable model to study osteoporosis. MATERIALS AND METHODS: Female rats with 6 and 36 weeks of age (n = 8 per group) were kept over a 20-week period and fed a diet for mature rodents complete in terms of Ca, phosphorous, and vitamin D. Excised femurs were measured for bone mass using dual-energy x-ray absorptiometry, morphometry, and biomechanical properties. The following serum mar-kers of bone metabolism were analyzed: parathyroid hormone (PTH), osteocalcin (OC), osteoprotegerin (OPG), receptor activator of nuclear factor Κappa B ligand (RANKL), C-terminal peptides of type I collagen (CTX-I), total calcium, and alkaline phosphatase (ALP) activity. RESULTS: Rats at 56 weeks of age showed important bone metabolism differences when compared with the younger group, such as, highest diaphysis energy to failure, lowest levels of OC, CTX-I, and ALP, and elevated PTH, even with adequate dietary Ca. CONCLUSION: Rats at 26-week-old rats may be too young to study age-related bone loss, whereas the 56-week-old rats may be good models to represent the early stages of age-related changes in bone metabolism.
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Universidade Estadual de Campinas . Faculdade de Educação Física
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Universidade Estadual de Campinas . Faculdade de Educação Física
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PURPOSE: Evaluate the bone tissue recovery following transplantation of ovine mesenchymal stem cells (MSC) from bone marrow and human immature dental-pulp stem cells (hIDPSC) in ovine model of induced osteonecrosis of femoral head (ONFH). METHODS: Eight sheep were divided in three experimental groups. First group was composed by four animals with ONFH induced by ethanol through central decompression (CD), for control group without any treatment. The second and third group were compose by two animals, six weeks after ONFH induction received transplantation of heterologous ovine MSC (CD + oMSC), and hIDPSC (CD + hIDPSC), respectively. In both experiments the cells were transplanted without application of any type of immunosupression protocol. RESULTS: Our data indicate that both cell types used in experiments were able to proliferate within injured site providing bone tissue recovery. The histological results obtained from CD+hIDPSC suggested that the bone regeneration in such animals was better than that observed in CD animals. CONCLUSION: Mesenchymal stem cell transplant in induced ovine osteonecrosis of femoral head by central decompression technique is safe, and apparently favors bone regeneration of damaged tissues.