Efeito do exercício aeróbio prévio realizado em diferentes cadências de pedalada sobre o número máximo de repetições na musculação e a capacidade de saltos

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Protocolos de treinamento aeróbio intervalado e da periodização para natação com ratos

Pós-graduação em Ciências da Motricidade - IBRC

Influência do exercício físico resistido no metabolismo da próstata de ratos UChB (bebedor voluntário de etanol a 10%)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Treinamento físico e antioxidantes enzimáticos no tecido cerebral de ratos diabéticos experimentais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Monitoring muscle damage markers during a four-week downhill walking exercise program

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da força, estresse muscular e marcadores inflamatórios de indivíduos com doença pulmonar obstrutiva crônica submetidos a treinamento resistido com tubos elásticos

Pós-graduação em Fisioterapia - FCT

Efeito da utilização do coringa no treinamento em campo reduzido em jogadores de futebol universitário

Soccer is the most popular sport in Brazil and one of the most popular in the world. Within this context, the practice of university soccer has increased the number of practitioners. A methodology widely used in the training of high performance teams are games reduced field ( JCR). The objective of this study was to evaluate the intensity of physical effort of football players during a small side game, 4x4, check the correlation between [La], HR PSE and the players and the floater influence on the intensity of the small side game. We analyzed eight players of UNESP in Bauru mean age 21.2+1.5 years, weight 75.8+11.6 kg, height 1.77±8cm, body fat percentage 12.3+5.5%, VO2max 37.1 ml/kg/min. The training was performed in 4 x 6 min with an interval of between one minute for recovery. The [La] and PSE were collected between the second and third time and after the end of training, the HR was measured every five seconds throughout the training through the RS400 heart rate monitor. A training session player floater participation (4x4+1) and the other not (4x4). The results presented showed no correlation with the HR [La] and PSE. HR significantly different, being 157+10 in the game 4x4+1 and 146+13 in the game 4x4. The percentage of HRmax in the game with floater was 81.3% and 75.7% in the game without. The players were most of the time in a higher intensity in the JCR with a floater, 37.8% of playing time over 85% HRmax, and 22.5% of playing time over 85% of HRmax in the JCR without floater, demonstrating that the use of a floater player made the game more intense and efficient to increase the intensity of the game

Efeito agudo do alongamento de diferentes grupos musculares no desempenho muscular de idosas

Among the numerous possibilities of physical exercise, it has been recommended that stretching routines should be incorporated into training programs focused on the elderly population, and that these routines should be preferentially performed on the same strength or aerobic training session. However, studies have shown that muscle strength production can be acutely impaired if it is preceded by static stretching exercises (AE). Although there seems to be a relationship between the number of stretched muscles and strength response, no studies were found examining such relationship in the same study, simultaneously. Thus, the objective of this study is to analyze the acute effect of stretching of different muscle groups on strength performance in older women. Nineteen physically active older women participated in the study (67.8 ± 5.3 years, 68.9 ± 12.4 kg, 157.2 ± 6.4 cm)-usar ponto final em inglês e não vírgula. The participants visited the lab for six consecutive days, three of which were intended to familiarization. Over the next three days, all the participants performed the experimental conditions: control; quadriceps stretching alone and complete stretching, involving the major extensors muscle groups of knees and hips. Both the two stretching conditions were realized with three series of 30s (total volume of 90 seconds for each exercise). All experimental conditions was be performed with an interval of at least 24 hours and order of execution was be randomized. The force transducer was connected to a leg press apparatus, where the isometric force time curve and electromyographic activity of the vastus medial and vastus lateralis were recorded. Measurements were registered immediately after each experimental condition, during five seconds. Statistical analysis comprised descriptive procedures and the One way ANOVA test for repeated measures (p<0.05). No statistically significant differences between the control and the two...

Avaliação da potência anaeróbia antes e após o período competitivo ematletas profissionais de futebol

The aim of this study was to examine changes on anaerobic power after competitive period in professional soccer players. Twenty five male was evaluated before (PRE) and after (POS) competitive period. To assess anaerobic power was used running based on anaerobic sprint test (RAST), which were determined the maximum power (MAXP), medium power (MEDP), minimum power (MINP) and fatigue index (FI). The test was performed in the first (PRE) and the last (POS) training session of competitive period, wich lasted 20 weeks. There were no significant difference (p>0,05) in POS condition compared to PRE condition on MAXP (10,70 ± 0,95 vs 10,83 ± 0,87), MINP (8,48 ± 0,92 vs 8,28 ± 0,76), MEDP (9,52 ± 0,83 vs 9,41 ± 0,61) and FI (22,73 ± 7,48 vs 25,53 ± 8,79). There was no significant change on anaerobic power after a competitive period wich lasted 20 weeks in professional soccer players.

Alteração da impulsão vertical após o período competitivo em atletas de profissionais de futebol

Change on vertical jump after competitive period in professionals soccer players. Brazilian Journal of Biomotricity, v. 4, n. 2, p. 140-147, 2010. Soccer is a sport that demands different intensities of run, with decisive actions of a match being held in maximum intensity. Vertical jump test is widely used in soccer players due to the strong relationship with speed and agility. Futhermore, there are little information about change on vertical jump after the competitive season in soccer players. The aim of this study was to analyze change on vertical jump after the competitive season in professional soccer players. Took part in this study 21 male athletes (20.82 ± 3.16 years, 72.28 ± 8.74 kg and 179.91 ± 6.14 cm) subscribers to the 4th division of the Paulista championship of 2009. The competitive season had a duration of 20 weeks, with a total of 20 official matchs done. The test used was the counter-movement vertical jump (VJ), that was performed in the first (PRE) and last (POS) training session of the competitive period. After confirmation of data normality by Kolmogorov-Smirnov, the inferential analysis of the results of VJ between PRE and POS was performed using the paired t-test, considering the significance level of 5%. There was a significant increase (p<0,05) on VJ after the competitive period (PRE=54,19±4,46 and POS=57,94±5,23). According to the results of this study, it is possible to increase the performance of VJ in professional soccer players after the competitive period of 20 weeks duration.

Resposta crônica e aguda da glicemia a um protocolo de treinamento misto para melhora da saúde de diabéticos tipo 2

The objective of the research was to evaluate the effect of a training program of physical exercises mixed (aerobic / anaerobic conditioning circuit-break with active), including exercises, walking, weight training and Swiss ball, caused about possible changes in their metabolic system, as changes acute and chronic, individuals bearers of DM2. The methodology used is a model of experimented design of pretest and post-test applied to the group. The blood glucose levels were analyzed in fasting pre-test and post-test, and capillary glycemia in three periods of physical exercise: pre, during and post training, and the statistical processing done by the use of Statistical Software for PC-For SPSS ® Windows ®, V. 12.0 .. With the result has been a drop in the values significant glucometers between 6 weeks of training, with a negative delta average of 68 mg / dl. Furthermore, similar results were also found variations in the daily glycemic between the moments before and after the training session acute. Thus we find that, regardless of the biological mechanism responsible, the program mixed aerobic and anaerobic conditioning circuit-break with active was effective in reducing and controlling chronic and acute glycemic of subjects type 2 diabetic.

Maximal strength, number of repetitions , and total volume are differently affected by static-ballistic, and proprioceptive neuromuscular facilitation stretching

Barroso, R, Tricoli, V, dos Santos Gil, S, Ugrinowitsch, C, and Roschel, H. Maximal strength, number of repetitions, and total volume are differently affected by static-, ballistic-, and proprioceptive neuromuscular facilitation stretching. J Strength Cond Res 26(9): 2432-2437, 2012-Stretching exercises have been traditionally incorporated into warm-up routines before training sessions and sport events. However, the effects of stretching on maximal strength and strength endurance performance seem to depend on the type of stretching employed. The objective of this study was to compare the effects of static stretching (SS), ballistic stretching (BS), and proprioceptive neuromuscular facilitation (PNF) stretching on maximal strength, number of repetitions at a submaximal load, and total volume (i.e., number of repetitions 3 external load) in a multiple-set resistance training bout. Twelve strength-trained men (20.4 +/- 4.5 years, 67.9 +/- 6.3 kg, 173.3 +/- 8.5 cm) volunteered to participate in this study. All of the subjects completed 8 experimental sessions. Four experimental sessions were designed to test maximal strength in the leg press (i.e., 1 repetition maximum [1RM]) after each stretching condition (SS, BS, PNF, or no-stretching [NS]). During the other 4 sessions, the number of repetitions performed at 80% 1RM was assessed after each stretching condition. All of the stretching protocols significantly improved the range of motion in the sit-and-reach test when compared with NS. Further, PNF induced greater changes in the sit-and-reach test than BS did (4.7 +/- 1.6, 2.9 +/- 1.5, and 1.9 +/- 1.4 cm for PNF, SS, and BS, respectively). Leg press 1RM values were decreased only after the PNF condition (5.5%, p < 0.001). All the stretching protocols significantly reduced the number of repetitions (SS: 20.8%, p < 0.001; BS: 17.8%, p = 0.01; PNF: 22.7%, p < 0.001) and total volume (SS: 20.4%, p < 0.001; BS: 17.9%, p = 0.01; PNF: 22.4%, p < 0.001) when compared with NS. The results from this study suggest that, to avoid a decrease in both the number of repetitions and total volume, stretching exercises should not be performed before a resistance training session. Additionally, strength-trained individuals may experience reduced maximal dynamic strength after PNF stretching.

Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders

Rationale Cannabidiol, the main nonpsychotropic constituent of Cannabis sativa, possesses a large number of pharmacological effects including anticonvulsive, sedative, hypnotic, anxiolytic, antipsychotic, anti-inflammatory, and neuroprotective, as demonstrated in clinical and preclinical studies. Many neurodegenerative disorders involve cognitive deficits, and this has led to interest in whether cannabidiol could be useful in the treatment of memory impairment associated to these diseases. Objectives We used an animal model of cognitive impairment induced by iron overload in order to test the effects of cannabidiol in memory-impaired rats. Methods Rats received vehicle or iron at postnatal days 12-14. At the age of 2 months, they received an acute intraperitoneal injection of vehicle or cannabidiol (5.0 or 10.0 mg/kg) immediately after the training session of the novel object recognition task. In order to investigate the effects of chronic cannabidiol, iron-treated rats received daily intraperitoneal injections of cannabidiol for 14 days. Twenty-four hours after the last injection, they were submitted to object recognition training. Retention tests were performed 24 h after training. Results A single acute injection of cannabidiol at the highest dose was able to recover memory in iron-treated rats. Chronic cannabidiol improved recognition memory in iron-treated rats. Acute or chronic cannabidiol does not affect memory in control rats. Conclusions The present findings provide evidence suggesting the potential use of cannabidiol for the treatment of cognitive decline associated with neurodegenerative disorders. Further studies, including clinical trials, are warranted to determine the usefulness of cannabidiol in humans suffering from neurodegenerative disorders.

L'influenza del sonno sull'andamento temporale della consolidazione delle abilità procedurali

Background: It is well known, since the pioneristic observation by Jenkins and Dallenbach (Am J Psychol 1924;35:605-12), that a period of sleep provides a specific advantage for the consolidation of newly acquired informations. Recent research about the possible enhancing effect of sleep on memory consolidation has focused on procedural memory (part of non-declarative memory system, according to Squire’s taxonomy), as it appears the memory sub-system for which the available data are more consistent. The acquisition of a procedural skill follows a typical time course, consisting in a substantial practice-dependent learning followed by a slow, off-line improvement. Sleep seems to play a critical role in promoting the process of slow learning, by consolidating memory traces and making them more stable and resistant to interferences. If sleep is critical for the consolidation of a procedural skill, then an alteration of the organization of sleep should result in a less effective consolidation, and therefore in a reduced memory performance. Such alteration can be experimentally induced, as in a deprivation protocol, or it can be naturally observed in some sleep disorders as, for example, in narcolepsy. In this research, a group of narcoleptic patients, and a group of matched healthy controls, were tested in two different procedural abilities, in order to better define the size and time course of sleep contribution to memory consolidation. Experimental Procedure: A Texture Discrimination Task (Karni & Sagi, Nature 1993;365:250-2) and a Finger Tapping Task (Walker et al., Neuron 2002;35:205-11) were administered to two indipendent samples of drug-naive patients with first-diagnosed narcolepsy with cataplexy (International Classification of Sleep Disorder 2nd ed., 2005), and two samples of matched healthy controls. In the Texture Discrimination task, subjects (n=22) had to learn to recognize a complex visual array on the screen of a personal computer, while in the Finger Tapping task (n=14) they had to press a numeric sequence on a standard keyboard, as quickly and accurately as possible. Three subsequent experimental sessions were scheduled for each partecipant, namely a training session, a first retrieval session the next day, and a second retrieval session one week later. To test for possible circadian effects on learning, half of the subjects performed the training session at 11 a.m. and half at 17 p.m. Performance at training session was taken as a measure of the practice-dependent learning, while performance of subsequent sessions were taken as a measure of the consolidation level achieved respectively after one and seven nights of sleep. Between training and first retrieval session, all participants spent a night in a sleep laboratory and underwent a polygraphic recording. Results and Discussion: In both experimental tasks, while healthy controls improved their performance after one night of undisturbed sleep, narcoleptic patients showed a non statistically significant learning. Despite this, at the second retrieval session either healthy controls and narcoleptics improved their skills. Narcoleptics improved relatively more than controls between first and second retrieval session in the texture discrimination ability, while their performance remained largely lower in the motor (FTT) ability. Sleep parameters showed a grater fragmentation in the sleep of the pathological group, and a different distribution of Stage 1 and 2 NREM sleep in the two groups, being thus consistent with the hypothesis of a lower consolidation power of sleep in narcoleptic patients. Moreover, REM density of the first part of the night of healthy subjects showed a significant correlation with the amount of improvement achieved at the first retrieval session in TDT task, supporting the hypothesis that REM sleep plays an important role in the consolidation of visuo-perceptual skills. Taken together, these results speak in favor of a slower, rather than lower consolidation of procedural skills in narcoleptic patients. Finally, an explanation of the results, based on the possible role of sleep in contrasting the interference provided by task repetition is proposed.

Seizure prediction and control in epilepsy

The first part of my thesis presents an overview of the different approaches used in the past two decades in the attempt to forecast epileptic seizure on the basis of intracranial and scalp EEG. Past research could reveal some value of linear and nonlinear algorithms to detect EEG features changing over different phases of the epileptic cycle. However, their exact value for seizure prediction, in terms of sensitivity and specificity, is still discussed and has to be evaluated. In particular, the monitored EEG features may fluctuate with the vigilance state and lead to false alarms. Recently, such a dependency on vigilance states has been reported for some seizure prediction methods, suggesting a reduced reliability. An additional factor limiting application and validation of most seizure-prediction techniques is their computational load. For the first time, the reliability of permutation entropy [PE] was verified in seizure prediction on scalp EEG data, contemporarily controlling for its dependency on different vigilance states. PE was recently introduced as an extremely fast and robust complexity measure for chaotic time series and thus suitable for online application even in portable systems. The capability of PE to distinguish between preictal and interictal state has been demonstrated using Receiver Operating Characteristics (ROC) analysis. Correlation analysis was used to assess dependency of PE on vigilance states. Scalp EEG-Data from two right temporal epileptic lobe (RTLE) patients and from one patient with right frontal lobe epilepsy were analysed. The last patient was included only in the correlation analysis, since no datasets including seizures have been available for him. The ROC analysis showed a good separability of interictal and preictal phases for both RTLE patients, suggesting that PE could be sensitive to EEG modifications, not visible on visual inspection, that might occur well in advance respect to the EEG and clinical onset of seizures. However, the simultaneous assessment of the changes in vigilance showed that: a) all seizures occurred in association with the transition of vigilance states; b) PE was sensitive in detecting different vigilance states, independently of seizure occurrences. Due to the limitations of the datasets, these results cannot rule out the capability of PE to detect preictal states. However, the good separability between pre- and interictal phases might depend exclusively on the coincidence of epileptic seizure onset with a transition from a state of low vigilance to a state of increased vigilance. The finding of a dependency of PE on vigilance state is an original finding, not reported in literature, and suggesting the possibility to classify vigilance states by means of PE in an authomatic and objectic way. The second part of my thesis provides the description of a novel behavioral task based on motor imagery skills, firstly introduced (Bruzzo et al. 2007), in order to study mental simulation of biological and non-biological movement in paranoid schizophrenics (PS). Immediately after the presentation of a real movement, participants had to imagine or re-enact the very same movement. By key release and key press respectively, participants had to indicate when they started and ended the mental simulation or the re-enactment, making it feasible to measure the duration of the simulated or re-enacted movements. The proportional error between duration of the re-enacted/simulated movement and the template movement were compared between different conditions, as well as between PS and healthy subjects. Results revealed a double dissociation between the mechanisms of mental simulation involved in biological and non-biologial movement simulation. While for PS were found large errors for simulation of biological movements, while being more acurate than healthy subjects during simulation of non-biological movements. Healthy subjects showed the opposite relationship, making errors during simulation of non-biological movements, but being most accurate during simulation of non-biological movements. However, the good timing precision during re-enactment of the movements in all conditions and in both groups of participants suggests that perception, memory and attention, as well as motor control processes were not affected. Based upon a long history of literature reporting the existence of psychotic episodes in epileptic patients, a longitudinal study, using a slightly modified behavioral paradigm, was carried out with two RTLE patients, one patient with idiopathic generalized epilepsy and one patient with extratemporal lobe epilepsy. Results provide strong evidence for a possibility to predict upcoming seizures in RTLE patients behaviorally. In the last part of the thesis it has been validated a behavioural strategy based on neurobiofeedback training, to voluntarily control seizures and to reduce there frequency. Three epileptic patients were included in this study. The biofeedback was based on monitoring of slow cortical potentials (SCPs) extracted online from scalp EEG. Patients were trained to produce positive shifts of SCPs. After a training phase patients were monitored for 6 months in order to validate the ability of the learned strategy to reduce seizure frequency. Two of the three refractory epileptic patients recruited for this study showed improvements in self-management and reduction of ictal episodes, even six months after the last training session.