La importancia de la opinión pública de Estados Unidos para la formulación de su política exterior: una revisión crítica al estado del arte

La disertación teórica clásica sobre la injerencia de la opinión pública en la formulación de la política exterior de los Estados Unidos estuvo enmarcada por el consenso de Almond y Lippmann, el cual arguye que la opinión pública es volátil, carente de estructura y que ejerce un impacto muy limitado en la conducción de la política externa; la opinión pública se identificó como una masa desarticulada y poco informada, y bajo el realismo político se acentuó este paradigma clásico.

Sesenta años de disputas: análisis del conflicto entre India y Pakistán por Cachemira

La presente disertación tiene el objetivo de analizar por qué el conflicto entre India y Pakistán por Cachemira no ha sido solucionado a la luz del debate entre el realismo ofensivo y el constructivismo social surgido en 1994. La hipótesis de trabajo establece que la estructura anárquica, sumada a las capacidades ofensivas, la desconfianza mutua, la racionalidad, y el deseo de supervivencia entre los Estados, ha propiciado la configuración de un dilema de seguridad que es alimentado por la disparidad de intereses e identidades en contienda. El alcance del objetivo es de carácter analítico y el enfoque primario está basado en la teoría del realismo ofensivo de John Mearsheimer y el constructivismo social de Alexander Wendt.

Why labor income shares seem to be constant?

The common assumptions that labor income share does not change over time or across countries and that factor income shares are equal to the elasticity of output with respect to factors have had important implications for economic theory. However, there are various theoretical reasons why the elasticity of output with respect to reproducible factors should be correlated with the stage of development. In particular, the behavior of international trade and capital flows and the existence of factor saving innovations imply such a correlation. If this correlation exists and if factor income shares are equal to the elasticity of output with respect to factors then the labor income share must be negatively correlated with the stage of development. We propose an explanation for why labor income share has no correlation with income per capita: the existence of a labor intensive sector which produces non tradable goods.

Desterrando minas

Desterrando minas es, a su vez, un documental de contexto y un documental de proceso. A partir de la inmersión en los mismos campamentos en los que viven los desminadores se cuenta la historia de Nariño como la vivieron sus pobladores, se muestra la manera en la que el miedo fue el principal configurador de las relaciones entre la comunidad y su territorio y cómo el desminado ha transformado ese miedo

Collaborative grid infrastructure for molecular simulations: The eMinerals minigrid as a prototype integrated computer and data grid

This paper describes a prototype grid infrastructure, called the eMinerals minigrid, for molecular simulation scientists. which is based on an integration of shared compute and data resources. We describe the key components, namely the use of Condor pools, Linux/Unix clusters with PBS and IBM's LoadLeveller job handling tools, the use of Globus for security handling, the use of Condor-G tools for wrapping globus job submit commands, Condor's DAGman tool for handling workflow, the Storage Resource Broker for handling data, and the CCLRC dataportal and associated tools for both archiving data with metadata and making data available to other workers.

Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus

Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen Staphylococcus aureus, is incompletely understood. Here we reveal widespread homologous recombination in S. aureus at the species level, in contrast to its near-complete absence between closely related strains. We discover a patchwork of hotspots and coldspots at fine scales falling against a backdrop of broad-scale trends in rate variation. Over megabases, homoplasy rates fluctuate 1.9-fold, peaking towards the origin-of-replication. Over kilobases, we find core recombination hotspots of up to 2.5-fold enrichment situated near fault lines in the genome associated with mobile elements. The strongest hotspots include regions flanking conjugative transposon ICE6013, the staphylococcal cassette chromosome (SCC) and genomic island νSaα. Mobile element-driven core genome transfer represents an opportunity for adaptation and challenges our understanding of the recombination landscape in predominantly clonal pathogens, with important implications for genotype–phenotype mapping.

Bennett Archambault Portrait

Portrait of Bennett Archambault who was a speaker at the evening school graduation of the New York Trade School in 1949. From a press release attached to the portrait: "Walter Weir, Inc., 250 West 57th Street, New York 19, N.Y., John Black, Public Relations & Publicity Department, Plaza 7-0140, May 23, 1949, For Release: Friday, May 27, 1949, BENNETT ARCHAMBAULT: Member of the Board of Trustees, New York Trade School, and Treasurer, The M.W. Kellogg Company, who reviewed the school's long history and drew an impressive picture of its future, in an address at the 68th Annual Evening School Graduation, held last night (May 26) in the school building on East 67th Street, New York." Black and white photograph.

Combination of the top-quark mass measurements from the Tevatron collider

The top quark is the heaviest known elementary particle, with a mass about 40 times larger than the mass of its isospin partner, the bottom quark. It decays almost 100% of the time to a W boson and a bottom quark. Using top-antitop pairs at the Tevatron proton-antiproton collider, the CDF and D0 Collaborations have measured the top quark's mass in different final states for integrated luminosities of up to 5.8fb -1. This paper reports on a combination of these measurements that results in a more precise value of the mass than any individual decay channel can provide. It describes the treatment of the systematic uncertainties and their correlations. The mass value determined is 173.18±0.56(stat)±0.75(syst)GeV or 173.18±0.94GeV, which has a precision of ±0.54%, making this the most precise determination of the top-quark mass. © 2012 American Physical Society.

Neural reprogramming in retinal degeneration.

PURPOSE: Early visual defects in degenerative diseases such as retinitis pigmentosa (RP) may arise from phased remodeling of the neural retina. The authors sought to explore the functional expression of ionotropic (iGluR) and group 3, type 6 metabotropic (mGluR6) glutamate receptors in late-stage photoreceptor degeneration. METHODS: Excitation mapping with organic cations and computational molecular phenotyping were used to determine whether retinal neurons displayed functional glutamate receptor signaling in rodent models of retinal degeneration and a sample of human RP. RESULTS: After photoreceptor loss in rodent models of RP, bipolar cells lose mGluR6 and iGluR glutamate-activated currents, whereas amacrine and ganglion cells retain iGluR-mediated responsivity. Paradoxically, amacrine and ganglion cells show spontaneous iGluR signals in vivo even though bipolar cells lack glutamate-coupled depolarization mechanisms. Cone survival can rescue iGluR expression by OFF bipolar cells. In a case of human RP with cone sparing, iGluR signaling appeared intact, but the number of bipolar cells expressing functional iGluRs was double that of normal retina. CONCLUSIONS: RP triggers permanent loss of bipolar cell glutamate receptor expression, though spontaneous iGluR-mediated signaling by amacrine and ganglion cells implies that such truncated bipolar cells still release glutamate in response to some nonglutamatergic depolarization. Focal cone-sparing can preserve iGluR display by nearby bipolar cells, which may facilitate late RP photoreceptor transplantation attempts. An instance of human RP provides evidence that rod bipolar cell dendrite switching likely triggers new gene expression patterns and may impair cone pathway function.