Lettres sur la religion et la politique adressées à l'abbé de la Mennais, le vicomte de Chateaubriand et le comte de Montlosier par H. Th. Tzschirner.

Mode of access: Internet.

Le glacier royal, ou, L'art de donner des bals et soirées : contenant les meilleures recettes pour faire les glaces, sorbets, café, punch, chocolats, thé, marmelades, confitures, pâtes, fruits à l'eau-de-vie, sirops, etc. : suivi de la construction d'une glacière, d'une distribution indiquant la quantité et l'ordre du service à faire pour recevoir depuis 25 jusqu'à 200 personnes, de menus de desserts de déjeuners, dîners et soupers pour les quatre saisons ... : ouvrage entièrement neuf ... /

Mode of access: Internet.

Sathānthī lǣ watthu sơng sāng nai ratchakān thī 4 /

Nāi Sīang Kannasūt phim nai ngān plong sop sanō̜ng khun bidā mơ̄a Ph.S. 2465.

Tarjamat ḥayāt al-maghfūr la-hu al-imām al-kabīr wa-al-ʻalam al-shahīr al-faqīh al-akbar fī ʻaṣrih wa-al-imām al-awḥad fī miṣrih al-Shaykh ʻAbd al-Qādir al-Rāfiʻī al-Fārūqī al-Ḥanafī Shaykh al-Sādah al-Ḥanafīyah wa-muftī al-diyār al-Miṣrīyah [microform] : mudhayyalah bi-aqwāl al-jarāʾid wa-marāthī al-ʻulamāʾ wa-al-udabāʾ fī al-aqṭār al-ʻArabīyah /

Microfilm.

Majmūʻat rasāʾil arbaʻah, al-ūlá Rafʻ al-ishtibāh ʻan ḥadīth man ṣallá fī masjidī arbaʻīn ṣalāh, al-thānīyah Tanbīh al-anām ʻan kayfīyat isqāṭ al-ṣalāh wa-al-ṣīyām, al-thālithah al-Kawākib al-lāmiʻāt fī ḥukm al-māʾiʻāt, al-rābiʻah Minnat al-Khāliq fī qawl al-rajul li-zawjatihi ghayr al-madkhūl bi-hā anti ṭāliq wa-ṭāliq wa-ṭāliq [microform] /

Microfilm.

The Monocarboxylate Transporter 8 and L-Type Amino Acid Transporters 1 and 2 Are Expressed in Mouse Skeletons and in Osteoblastic MC3T3-E1 Cells

Background: Several plasma membrane transporters have been shown to mediate the cellular influx and/or efflux of iodothyronines, including the sodium-independent organic anion co-transporting polypeptide 1 (OATP1), the sodium taurocholate co-transporting polypeptide (NTCP), the L-type amino acid transporter 1 (LAT1) and 2 (LAT2), and the monocarboxylate transporter 8 (MCT8). The aim of this study was to investigate if the mRNAs of these transporters were expressed and regulated by thyroid hormone (TH) in mouse calvaria-derived osteoblastic MC3T3-E1 cells and in the fetal and postnatal bones of mice. Methods: The mRNA expression of the iodothyronine transporters was investigated with real-time polymerase chain reaction analysis in euthyroid and hypothyroid fetuses and litters of mice and in MC3T3-E1 cells treated with increasing doses of triiodothyronine (T(3); 10(-10) to 10(-6) M) or with 10(-8) M T(3) for 1-9 days. Results: MCT8, LAT1, and LAT2 mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 and NTCP mRNAs were not. LAT1 and LAT2 mRNAs were not affected by TH status in vivo or in vitro or by the stage of bone development or osteoblast maturation (analyzed by the expression of osteocalcin and alkaline phosphatase, which are key markers of osteoblastic differentiation). In contrast, the femoral mRNA expression of MCT8 decreased significantly during post-natal development, whereas MCT8 mRNA expression increased as MC3T3-E1 cells differentiated. We also showed that MCT8 mRNA was up-regulated in the femur of hypothyroid animals, and that it was down-regulated by treatment with T(3) in MC3T3-E1 cells. Conclusions: This is the first study to demonstrate the mRNA expression of LAT1, LAT2, and MCT8 in the bone tissue of mice and in osteoblast-like cells. In addition, the pattern of MCT8 expression observed in vivo and in vitro suggests that MCT8 may be important to modulate TH effects on osteoblast differentiation and on bone development and metabolism.

Th structure of the P-II-ATP complex

P-II is a signal transduction protein that is part of the cellular machinery used by many bacteria to regulate the activity of glutamine synthetase and the transcription of its gene. The structure of P-II was solved using a hexagonal crystal form (form I). The more physiologically relevant form of P-II is a complex with small molecule effecters. We describe the structure of P-II with ATP obtained by analysis of two different crystal forms (forms II and III) that were obtained by co-crystallization of P-II with ATP. Both structures have a disordered recognition (T) loop and show differences at their C termini. Comparison of these structures with the form I protein reveals changes that occur on binding ATP. Surprisingly, the structure of the P-II/ATP complex differs with that of GlnK, a functional homologue. The two proteins bind the base and sugar of ATP in a similar manner but show differences in the way that they interact with the phosphates. The differences in structure could account for the differences in their activities, and these have been attributed to a difference in sequence at position 82. It has been demonstrated recently that P-II and GlnK form functional heterotrimers in vivo. We construct models of the heterotrimers and examine the junction between the subunits.

E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein

A line of FVB (H-2(q)) mice transgenic for the E6/E7 open reading frames of Human Papillomavirus type 16 driven from the alpha-A crystallin promoter expresses E7 mRNA in lens and skin epithelium. E7 protein is detectable in adult skin, coinciding with the development or inflammatory skin disease, which progresses to papillomata and squamous carcinomata in some mice. By examining the outcome of parenteral immunization with E7 protein, we sought to determine whether endogenous expression of E7 in skin had induced a preexisting immune outcome, i.e., specific immunity or tolerance, or whether the mice remain naive (''ignorant'') to E7. Our data show that the antibody response to defined E7 B-epitopes, the proliferative response to Th epitopes, and the delayed-type hypersensitivity (DTH) response to whole E7 did not differ between groups or young and old E6/E7 transgenic mice (likely having different degrees of lifetime exposure to E7 protein) or between E6/E7-transgenic and nontransgenic parental strain control mice. Although an E7-specific CTL response could not be induced in the H-2(q) background of these mice, incorporation of a D-b allele into the genome allowed comparison of D-b-restricted CTL responses in E6/E7 transgenic and nontransgenic mice. Experiments indicated that the E7-immunization-induced CTL response did not differ significantly between E6/E7 transgenic and nontransgenic mice. We interpret these results to indicate that in spite of expression of E7 protein in adult skin, E6/E7 transgenic mice remain immunologically naive (ignorant) of E7 epitopes presented by immunization. (C) 1997 Academic Press.

Conspectus floræ Africæ, ou Énumération des plantes d'Afrique, par Th. Durand ... et Hans Schinz ...

v.1, pt.2

Doses and methods of distribution of potassium chloride on soybean crop (Glycine max (L.) Merrill) in a red latosol, affecting soil salinity, grain production and chemical composition of leaves

The present work deal t wi th an experiment under field conditions and a laboratory test of soil incubation the objectives were as follows: a. to study effects on soybean grain product ion and leaf composition of increasing doses of potassium chloride applied into the soil through two methods of distribution; b. to observe chemical modifications in the soils incubated with increasing doses of potassium chloride; and, c. to correlate field effects with chemical alterations observed in the incubation test, The field experiment was carried out in a Red Latosol (Haplustox) with soybean cultivar UFV - 1. Potassium chloride was distributed through two methods: banded (5 cm below and 5 cm aside of the seed line) and broadcasted and plowed-down. Doses used were: 0; 50; 100 and 200 kg/ha of K2O. Foliar samples were taken at flowering stage. Incubation test were made in plastic bags with 2 kg of air dried fine soil, taken from the arable layer of the field experiment, with the following doses of KC1 p,a. : 0; 50; 100; 200; 400; 800; 1,600; 3.200; 6,400 and 12,800 kg/ha of K(2)0. In the conditions observed during the present work, results allowed the following conclusions: A response by soybean grain production for doses of potassium chloride, applied in both ways, banded or broadcasted, was not observed. Leaf analysis did not show treatment influence over the leaf contents for N, P, K, Ca, Mg, and CI, Potassium chloride salinity effects in both methods of distribution for all the tested closes were not observed.

Contribution à l'élaboration de mécanismes de détection, de contrôle et de lutte contre le blanchiment d'argent au regard de l'usage des technologies de l'information et de la communication "cas de l'Algérie"

Résumé : Désormais, la lutte contre le blanchiment d'argent constitue une priorité pour les Etats et les gouvernements dans le but, d'une part, de préserver l'économie et l'intégrité des places financières et, d'autre part, de priver les organisations criminelles des ressources financières. Dans ce contexte, la préoccupation majeure des autorités algériennes en charge de la lutte contre ce phénomène est de mettre en place un dispositif capable de détecter les mécanismes de blanchiment, d'en évaluer la menace et sur la base de cette connaissance, de définir et de déployer les moyens de riposte les plus efficaces et efficients. Mais nous constatons que mener des enquêtes de blanchiment en conséquence à un crime sous-jacent a montré ses limites en matière d'établissement de preuves, d'élucidation d'affaires et de recouvrement des avoirs. Par ailleurs, nous pensons qu'il serait plus judicieux de mettre en place en amont un contrôle «systématique» des flux financiers et des opérations inhabituelles et/ou suspectes et de là, identifier d'éventuelles opérations de blanchiment, sans forcément connaître le crime initial, en veillant au maintien de l'équilibre entre le «tout sécuritaire» orienté vers la surveillance accrue des flux et la préservation de la vie privée et des libertés individuelles. Notre thèse apporte un regard critique sur le dispositif actuel de lutte contre le blanchiment existant en Algérie que nous évaluons et sur lequel nous relevons plusieurs lacunes. Pour répondre aux problèmes identifiés nous proposons des solutions stratégiques, organisationnelles, méthodologiques et technologiques intégrées dans un cadre opérationnel cohérent au niveau national et international.

Desequilibri 234Th/238U per a l'estudi del cicle de partícules al Mediterrani nord-occidental

El desequilibri 238U/234Th s’utilitza per traçar el cicle de les partícules a la part més superficial dels oceans. Això és possible degut a les diferències entre els seus períodes de semidesintegració (T1/2 (234Th)=24,1 d; T1/2 (238U)=4,5 10 9 anys) i a les seves característiques biogeoquímiques: el Th presenta una gran afinitat per les partícules mentre que l’U és conservatiu en aigua de mar. En absència de partícules s’esperaria tenir equilibri secular entre ambdós radionúclids, però com que l’oceà no està lliure de partícules, el 234Th és exportat des de les capes més superficials produint-se un dèficit respecte el seu pare, l’238U. El període de semidesintegració del 234Th és molt adequat per traçar processos d’escales temporals de dies a setmanes, del mateix ordre que el desenvolupament de la floració del fitoplàncton i a la posterior exportació de partícules. En aquest treball es presenten dades obtingudes durant dues campanyes oceanogràfiques realitzades en el marc del Projecte FAMOSO (2009) en el Mediterrani nordoccidental, abans i després de la floració de fitoplàncton de primavera a la zona. Una de les peculiaritats d’aquesta regió és el procés de convecció profunda d’hivern, el qual suposa un important mecanisme de fertilització. A partir dels fluxos de 234Th obtinguts a la columna d’aigua es poden establir les pautes temporals que ha seguit el fitoplàncton en les setmanes prèvies al mostreig. Aquesta informació es compara amb els fluxos obtinguts utilitzant trampes de sediment a la deriva instal·lades durant ambdues campanyes.