Iowa 100% E News, May/June 2001, Vol.1, no.4

Newsletter for Information Technology Department

Iowa 100% E News, July/August 2001, Vol.1, no.5

Newsletter for Information Technology Department

Iowa 100% E News, August/September 2001, Vol.1, no.6

Newsletter for Information Technology Department

Iowa 100% E News, December 2001, Vol.1 no.8

Newsletter for Information Technology Department

The genomic impact of 100 million years of social evolution in seven ant species.

Ants (Hymenoptera, Formicidae) represent one of the most successful eusocial taxa in terms of both their geographic distribution and species number. The publication of seven ant genomes within the past year was a quantum leap for socio- and ant genomics. The diversity of social organization in ants makes them excellent model organisms to study the evolution of social systems. Comparing the ant genomes with those of the honeybee, a lineage that evolved eusociality independently from ants, and solitary insects suggests that there are significant differences in key aspects of genome organization between social and solitary insects, as well as among ant species. Altogether, these seven ant genomes open exciting new research avenues and opportunities for understanding the genetic basis and regulation of social species, and adaptive complex systems in general.

Iowa 100% E News, March 2002, Vol.2, no.3

Newsletter for the Information Technology Department

Iowa 100% E News, October/November 2001, Vol.1, no.7

Newsletter for the Information Technology Department

Iowa 100% E News, January 2002, Vol.2, no.1

Newsletter for the Information Technology Department

Iowa 100% E News, February 2002, Vol.2, no.2

Newsletter for the Information Technology Department

Systematic molecular and cytogenetic screening of 100 patients with marfanoid syndromes and intellectual disability.

The association of marfanoid habitus (MH) and intellectual disability (ID) has been reported in the literature, with overlapping presentations and genetic heterogeneity. A hundred patients (71 males and 29 females) with a MH and ID were recruited. Custom-designed 244K array-CGH (Agilent®; Agilent Technologies Inc., Santa Clara, CA) and MED12, ZDHHC9, UPF3B, FBN1, TGFBR1 and TGFBR2 sequencing analyses were performed. Eighty patients could be classified as isolated MH and ID: 12 chromosomal imbalances, 1 FBN1 mutation and 1 possibly pathogenic MED12 mutation were found (17%). Twenty patients could be classified as ID with other extra-skeletal features of the Marfan syndrome (MFS) spectrum: 4 pathogenic FBN1 mutations and 4 chromosomal imbalances were found (2 patients with both FBN1 mutation and chromosomal rearrangement) (29%). These results suggest either that there are more loci with genes yet to be discovered or that MH can also be a relatively non-specific feature of patients with ID. The search for aortic complications is mandatory even if MH is associated with ID since FBN1 mutations or rearrangements were found in some patients. The excess of males is in favour of the involvement of other X-linked genes. Although it was impossible to make a diagnosis in 80% of patients, these results will improve genetic counselling in families.

Jugement... de la capitainerie royale de Senart, qui condamne Jean Rabot, vigneron à Mainville, en 100 livres d'amende, comme responsable de son fils ayant écrasé un nid contenant sept oeufs de perdrix

[Acte. 1778-08-24. Montgeron]

Jugement... de la capitainerie royale de Senart, qui condamne le Sr Le Paige, seigneur de Quincy, en 100 livres d'amende, pour avoir tiré et chassé aux lapins dans son parc de Quincy, nonobstant les défenses à lui faites

[Acte. 1778-08-24. Montgeron]