Tax�� cancellari�� apostolic�� et tax�� sacr�� poenitentiari�� apostolic��. Dat is, schattinge van de cancellarie en penitentie-kamer van den Paus van Romen, gecollationeert, gedruckt ende geautentizeert nae 't exemplaar van Leo X. tot Romen anno 1514.

Mode of access: Internet.

Die Mainzer Erzbischofswahl vom Jahre 1514 und der Streit um Erfurt in ihren gegenseitigen Beziehungen.

Thesis (doctoral)--Rheinische Friedrich-Wilhelms-Universitat zu Bonn.

Carlyle on heroes, hero-worship : and the heroic in history /

Six lectures.

A Capitania-mor do Mar da ��ndia : 1502-1564

A presente disserta����o pretende compreender as origens e a actividade associada �� capitania-mor do mar da ��ndia, considerado o segundo cargo mais relevante da estrutura pol��tico-militar do Estado Portugu��s da ��ndia, desde 1502 a 1564. Este cargo, transferido do reino para a ��ndia, ainda nos prim��rdios da presen��a portuguesa, em 1502, visou assegurar os interesses da Coroa na ��sia. Ap��s a nomea����o do primeiro vice-rei para a ��ndia, D. Francisco de Almeida, em 1505, este of��cio foi desde logo disputado e requerido pelos governadores subsequentes. Na maioria das vezes era-lhes concedida a possibilidade de indicarem ao soberano quem pretendiam ao seu lado, para os auxiliar na realiza����o do plano de expans��o gizado pela Coroa. No entanto, ao monarca assistia a palavra final. Procuramos saber quem foram os oficiais que ocuparam a capitania e compreender que espa��o era esse ���Mar da ��ndia���. Considerado o controlo do mar como a base da afirma����o e alargamento da presen��a portuguesa na ��sia, de acordo com os planos de expans��o de D. Manuel I e D. Jo��o III, �� relevante percebermos qual foi a ��rea de autoridade desta capitania. Se o espa��o �� relevante, tamb��m as embarca����es o s��o, por isso, tentamos perceber que tipos de embarca����es faziam parte das armadas associadas a este of��cio. Ap��s o entendimento sobre o espa��o e as embarca����es, foi relevante percebermos os crit��rios da nomea����o e as fun����es inerentes, as quais eram, sobretudo, do foro pol��tico-militar. Todavia, os poderes outorgados �� capitania, de natureza mar��tima, foram por vezes alargados ��s pra��as portuguesas do Estado da ��ndia. Percepcionar de que forma e para que fins essa autoridade se ampliou tamb��m foi motivo de discuss��o. Compreender o estatuto social e o impacto do cargo nas traject��rias individuais, foram aspectos que foram tidos em linha de conta ao longo do nosso estudo. Tentamos igualmente avan��ar com hip��teses explicativas sobre o fim deste cargo. Com este estudo pretendemos compreender como a capitania-mor do mar da ��ndia fez parte do funcionamento da c��pula pol��tico-militar do Estado Portugu��s da ��ndia, ao longo de mais de meio s��culo, como elemento estabilizador. Constatamos que o capit��o-mor do mar tamb��m foi usado pelo rei, com o intuito de controlar o governador em fun����es.

Estimaci��n del costo de los elementos de seguridad necesarios para controlar los riesgos existentes en el proceso constructivo del Edificio Jard��n 1564

81 p.

Elites instruidas en la Costa Rica colonial, 1564-1718

ResumenHaciendo uso de la metodolog��a prosopogr��fica y de un enfoque te��rico de redes sociales, el presente art��culo se propone investigar el funcionamiento social del conocimiento, as�� como sus mecanismos de transmisi��n en la sociedad colonial de Costa Rica. Tambi��n se lleva a cabo una presentaci��n documental de las principales l��neas de evoluci��n institucional de la educaci��n en la ��poca. Se llega as�� a constatar que el conocimiento estaba en manos de una estrecha red social de individuos conectados, enriquecidos y empoderados, que formaban parte de la elite pol��tica colonial, quienes lo vedaban sistem��ticamente a otros sectores sociales de la ��poca, y lo empleaban para apuntalar su posici��n social.AbstractBy means of a prosopographic study and using a social networks theoretical approach, this article explores the social functions of knowledge, as well as its ways of transmission in the Costarican colonial society. A documented presentation of the main traits of the evolution of the formal education in the period is also offered. As a result, the work concludes that knowledge was in the hands of a very narrow social network structured with very well connected individuals, who were also rich and politically powerful. These individuals used their position and their monopoly of knowledge to impede access to it to other social groups of the time, using it, at the same time, as a tool to sustain their social position.

Characterization of different fruit wines made from cacao, cupuassu, gabiroba, jaboticaba and umbu

The main aim of this work was to produce fruit wines from pulp of gabiroba, cacao, umbu, cupuassu and jaboticaba and characterize them using gas chromatography-mass spectrometry for determination of minor compounds and gas chromatography-flame ionization detection for major compounds. Ninety-nine compounds (C(6) compounds, alcohols, monoterpenic alcohols, monoterpenic oxides, ethyl esters, acetates, volatile phenols, acids, carbonyl compounds, sulfur compounds and sugars) were identified in fruit wines. The typical composition for each fruit wine was evidenced by principal component analysis and Tukey test. The yeast UFLA CA 1162 was efficient in the fermentation of the fruit pulp used in this work. The identification and quantification of the compounds allowed a good characterization of the fruit wines. With our results, we conclude that the use of tropical fruits in the production of fruit wines is a viable alternative that allows the use of harvest surpluses and other underused fruits, resulting in the introduction of new products into the market. (C) 2010 Elsevier Ltd. All rights reserved.

Thermodynamics of aqueous solutions of polyelectrolytes: Experimental results for the activity of water in aqueous solutions of some single synthetic polyelectrolytes

Experimental results for the activity of water in aqueous solutions of 10 single polyelectrolytes (two polysodium acrylates, two polysodium methacrylates, three polyammonium acrylates, two polysodium ethylene sulfonates, and one polysodium styrene sulfonate) at (298.2 and 323.2) K are reported. The isopiestic method was employed in these experiments with aqueous solutions of sodium chloride as references. The polyelectrolytes were characterized by three averaged molecular masses determined by gel permeation chromatography. Furthermore, the density and the refractive index increments of the aqueous polyelectrolyte solutions are reported. Although a similar pattern for the activity of water was observed for all systems (i.e., the osmotic coefficient increases with rising polyelectrolyte concentration), the experimental results show that this property depends on the monomer type as well as on the size of the polymer chain. The temperature (varied from (298.2 to 323.2) K) has only a small influence on the activity of water.

Bioreduction of Acetophenone Derivatives by Red Marine Algae Bostrychia radicans and B. tenella, and Marine Bacteria Associated

The biocatalytic reduction of acetophenone derivatives was exploited by using algal biomass from Bostrychia radicans and B. tenella producing exclusively (S)-2-phenylethanols with high enantiomeric excess (> 99% ee). Bacterial populations associated with algal biomass were identified as the Bacillus genus. This report deals with the first investigations involving the use of marine bacteria associated with B. radicans and B. tenella marine algae for the biocatalytic reduction of acetophenone derivatives.

An alpha-type phospholipase A(2) inhibitor from Bothrops jararacussu snake plasma: Structural and functional characterization

An inhibitory protein that neutralizes the enzymatic, toxic and pharmacological activities of several phospholipases A(2) from Bothrops venoms was isolated from B. jararacussu snake plasma by affinity chromatography using the immobilized myotoxin BthTX-I on Sepharose gel. Biochemical characterization of this inhibitory protein, denominated alpha BjussuMIP, showed it to be an oligomeric glycoprotein with M-r of 24,000 for the monomeric subunit. Secondary structural analysis by circular dichroism revealed 44% alpha-helix, 18% beta-sheet, 10% beta-turn and 28% random coil structures. Circular dichroism spectroscopy indicated that no significant alterations in the secondary structure of either alpha BjussuMIP or the target protein occur following their interaction. The product from the reaction with reverse transcriptase produced a cDNA fragment of 432 bp that codifies for a mature protein of 144 amino acid residues. The first 21 amino acid residues from the N-terminal and five tryptic peptides were characterized by mass spectrometry of the mature protein and confirmed by the nucleotide sequence. Alignment of alpha BjussuMIP with other snake inhibitors showed a sequence similarity of 73-92% with these alpha PLIs. alpha BjussuMIP was relatively stable within the pH range of 6-12 and temperatures from 0 degrees C to 80 degrees C, even after deglycosylation. The results showed effects against Bothrops phospholipase A(2) activities (enzymatic, edema inducing, myotoxic, cytotoxic and bactericidal), suggesting that alpha BjussuMIP may prove useful in the treatment of snakebite envenomations. (C) 2008 Elsevier Masson SAS. All rights reserved.

Women drivers' behaviour, socio-demographic characteristics and accidents

The purpose of this study was to examine factors which affect driving behaviour and accident rates in women in Australia. Two groups of women (aged 18-23 and 45-50 years) participating in the Australian Longitudinal Study on Women's Health, completed a mailed questionnaire on driver behaviour and road accidents. Self reported accident rates in the last 3 years were 1.87 per 100 000 km for the young drivers (n = 1199) and 0.59 per 100 000 km for the mid-age drivers (n = 1564); most accidents involved damage only, not injury. Mean scores for lapses obtained using the Driver Behaviour Questionnaire, were similar in the two age groups and similar to those found in other studies. In contrast, scores for errors and violations for the young women were higher than for the mid-age group and previous reports using the same instruments. Riskier driving behaviour among young women was associated with stress and habitual alcohol consumption. In the mid-age group, poorer driver behaviour scores were related to higher levels of education, feeling rushed, higher habitual alcohol consumption and lower life satisfaction scores. Accident rates in both groups were significantly related to lapses. Women born in non-English speaking countries had significantly higher risk of accidents compared to Australian-born women: relative risk = 3.40, 95% confidence interval (1.93, 5.98) for the young drivers; relative risk = 1.77, 95% confidence interval (1.11, 2.83) for mid-age drivers. These findings support the need for road safety campaigns targeted at young women to reduce dangerous driving practices, such as speeding,'tail gating' and overtaking on the inside. There is also a need for further research to understand how lifestyle characteristics are associated with higher risk of accidents and to explore factors which might account for the higher risk for women drivers who were born overseas. (C) 1999 Elsevier Science Ltd. All rights reserved.

Incidence of ipsilateral postoperative deep venous thrombosis in the amputated lower extremity of patients with peripheral obstructive arterial disease

Objective: Patients undergoing amputation of the lower limb due to peripheral arterial disease (PAD) are at risk of developing deep venous thrombosis (DVT). Few studies in the research literature report the incidence of DVT during the early postoperative period or the risk factors for the development of DVT in the amputation stump. This prospective study evaluated the incidence of DVT during the first 35 postoperative days in patients who had undergone amputation of the lower extremity due to PAD and its relation to comorbidities and death. Methods: Between September 2004 and March 2006, 56 patients (29 men), with a mean age of 67.25 years, underwent 62 amputations, comprising 36 below knee amputations (BKA) and 26 above knee amputations (AKA). Echo-Doppler scanning was performed preoperatively and on postoperative days 7 and 31 (approximately). All patients received acetylsalicylic acid (100 mg daily) preoperatively and postoperatively, but none received prophylactic anticoagulation. Results: DVT occurred in 25.8% of extremities with amputations (10 ARA and 6 BKA). The cumulative incidence in the 35-day postoperative period was 28% (Kaplan-Meier). There was a significant difference (P = .04) in the incidence of DVT between AKA (37.5%) and BKA (21.2%). Age >= 70 years (48.9% vs 16.8%, P = .021) was also a risk factor for DVT in the univariate analysis. Of the 16 cases, 14 (87.5%) were diagnosed during outpatient care. The time to discharge after amputation was averaged 6.11 days in-hospital stay (range, 1-56 days). One symptomatic nonfatal pulmonary embolism occurred in a patient already diagnosed with DVT. There was no relation between other comorbidities and DVT. The multivariate analysis showed no association between risk factors and the occurrence of DVT in the amputated extremity. DVT ipsilateral to the amputation did not influence the mortality rate (9.7%). Conclusion: The incidence of DVT in the early postoperative period (<= 35 days) was elevated principally in patients aged >= 70 years and for AKA. Patients with PAD who have recently undergone major amputations should be considered at high risk for DVT, even after hospital discharge. Given the high rate of postoperative DVT observed in this study, we now recommend prophylactic anticoagulation for these patients, but further study is needed to determine the optimal duration and efficacy of this treatment. (J Vasc Surg 2008;48:1514-9.)

Interieukin-17 and Kidney Allograft Outcome

Acute rejection episodes (ARE) are important complications that involve the interplay between mechanisms that maintain graft tolerance and promote rejection. The proinflammatory cytokine interieukin-17 (IL-17) has been implicated in many conditions in humans and mice. In kidney transplant patients, the evaluation IL-17 levels has been performed in only a few patients. We performed a cross-sectional study correlating quantitative IL-17 levels and clinical outcomes. Patients and methods. We studied 19 specimens from biopsies performed in patients (n = 19) who received isolated kidney grafts. ARE signs were present in 9 (47%) patients who provide specimens; whereas, 10 (53%) others showed no signs of rejection. Eighteen healthy control sample IL-17 underwent measurement, all of which were performed by an enzyme-linked immunosorbent assay method. We assessed other factors, such as the recipients demographic data, cold ischemia time, HLA mismatches, time elapsed from transplantation to the biopsy, posttransplantation status, antibody panel, donor type, and immunosuppressive treatment. Results. IL-17 levels were clearly increased among samples derived from patients with ongoing rejection (125.7 +/- 27.06 pg/mL) in contrast, to the nonrejection group, (30 +/- 13.32 pg/mL) (P < .05). Healthy controls showed no detectable IL-17 levels. Conclusions. These findings suggested that IL-17 was important in the pathophysiology of acute kidney rejection.

Determination of para-Chloroaniline and Reactive Oxygen Species in Chlorhexidine and Chlorhexidine Associated with Calcium Hydroxide

The aim of this study was to determine whether para-chloroaniline (PCA) and/or reactive oxygen species (ROS) are generated by chlorhexidine (CHX) alone or after CHX is mixed with calcium hydroxide at different time points. Mass spectrometry was performed to detect PCA in samples of 0.2% CHX and Ca(OH)2 mixed with 0.2% CHX. High-performance liquid chromatography was used to confirm the presence of CHX in the mixture with Ca(OH)2. The samples were analyzed immediately after mixing and after 7 and 14 days. During the intervals of the experiment, the samples were maintained at 36.5 degrees C and 95% relative humidity. PCA was detected in the 0.2% CHX solution after 14 days. The mixture of CHX with Ca(CH)2 liberated ROS at all time points, but no traces of CHX were present in the mixture as a result of immediate degradation of the CHX. (J Endod 2008;34:1508-1514)