Por Iacinto Forner generoso, señor... de Benasau, y demas herederos de la quondam Iusepa Bernabeu y de Forner viuda, su madre con Thomas Salafranca.

Precede al tit.: "Iesus, Maria, Ioseph"

Functional hubs in mild cognitive impairment

We investigate how hubs of functional brain networks are modified as a result of mild cognitive impairment (MCI), a condition causing a slight but noticeable decline in cognitive abilities, which sometimes precedes the onset of Alzheimer's disease. We used magnetoencephalography (MEG) to investigate the functional brain networks of a group of patients suffering from MCI and a control group of healthy subjects, during the execution of a short-term memory task. Couplings between brain sites were evaluated using synchronization likelihood, from which a network of functional interdependencies was constructed and the centrality, i.e. importance, of their nodes was quantified. The results showed that, with respect to healthy controls, MCI patients were associated with decreases and increases in hub centrality respectively in occipital and central scalp regions, supporting the hypothesis that MCI modifies functional brain network topology, leading to more random structures.

El Mejor Padre del Mundo : Sermon del Gran Patriarca San Joaquin que en la villa de Torredembarra, dia 16 de agosto de 1789

Sign.: A-F4

Carta critica de D. Alvaro Gil de la Sierpe al autor de la obra intitulada Atlante español ... se vindica a Gaspar de Escolano

Alvaro Gil de la Sierpe es seudonimo de Valcarcel Pio de Saboya y Moura, Antonio.

Simbiosis bacteriana y conservación de flora amenazada: el caso del Lupinus mariae-josephae.

Lupinus mariae-josephae H. Pascual es un altramuz endémico de un reducido número de sitios en la Comunidad Valenciana, donde coloniza sustratos de ?terra rossa? sobre afloramientos de lapiaz. Descrito en 2004 a partir de plantas cultivadas, no pudo localizarse en campo hasta 2006, y el hallazgo de sus poblaciones ha estado estrechamente ligado a topónimos relativos a su nombre popular, ?tramús? en valenciano. Se ha demostrado la clara independencia genética, y en consecuencia el valor como ?buen taxon? de esta especie. Hasta ahora se han caracterizado y censado cinco poblaciones silvestres en diferentes localidades, y en todas ellas se observan fuertes fluctuaciones interanuales de sus efectivos, a veces acompañadas de importantes diferencias de vigor de los ejemplares; tres de estas poblaciones están actualmente protegidas mediante sendas microrreservas de flora. Algunos de estos núcleos poblacionales se componen en años concretos de formas poco vigorosas, que a menudo sólo producen 1-2 frutos con 1-2 semillas; por el contrario, las formas más vigorosas pueden producir varias docenas de semillas. La emergencia de plántulas se produce con gran probabilidad tras años de progresiva escarificación de la cubierta de las semillas en el suelo, y probablemente se acelera por procesos de reducción de la cubierta vegetal como los incendios forestales. La germinación experimental ex situ sólo se consigue satisfactoriamente mediante el pretratamiento de escaldado de las semillas.

El alma victoriosa de la passion dominante por medio del examen particular de la conciencia de los exercicios cotidianos y practica de las devociones : obra utilissima que consagra al apostol de Las Indias ... el P. Francisco Xavier Hernandez de la Compañia de Jesus

Colofón en p. 256

Modo breue de seruir a Ntro. Señor en diez reglas

Contiene: Tratado I. Modo de servir a Dios; Tratado II. Explicacion de las Bieneventuranzas ; Tratado III. Soliloquio para despues de la comunion

Vibration reduction for vision systems on board unmanned aerial vehicles using a neuro-fuzzy controller

In this paper, an intelligent control approach based on neuro-fuzzy systems performance is presented, with the objective of counteracting the vibrations that affect the low-cost vision platform onboard an unmanned aerial system of rotating nature. A scaled dynamical model of a helicopter is used to simulate vibrations on its fuselage. The impact of these vibrations on the low-cost vision system will be assessed and an intelligent control approach will be derived in order to reduce its detrimental influence. Different trials that consider a neuro-fuzzy approach as a fundamental part of an intelligent semi-active control strategy have been carried out. Satisfactory results have been achieved compared to those obtained by means of vibration reduction passive techniques.

El arte poética de Nicolas Boileau Despreau

Sign.: A-T4

Study of the temperature distribution in Si nanowires under microscopic laser beam excitation

Study of the temperature distribution in Si nanowires under microscopic laser beam excitation

Sermon, que ...

Apéndice: p. 29-12

Encomios funebres ascetico-panegiricos, que en las honras, i exequias de ... Josefa Benlloch

Sign. : [calderón]4, 2[calderón]2, A-I4, K2

Nitrogen fixation by native Bradyrhizobia in symbiosis with Lupinus mariae-josephae requires a T3SS encoding a NopE-like effector

Several bradyrhizobial isolates from L. mariae-josephae root nodules [1] contain a type III secretion system (T3SS) within a cluster of about 30 genes. Among those genes, ttsI codes for the transcriptional activator of the system. Mutation of ttsI resulted in the formation of white, non-fixing nodules with the natural legume host, L. mariae-josephae. The T3SS cluster also contains a gene coding for a NopE-like protein. NopE proteins have been demonstrated to be effectors in the Bradyrhizobium-soybean symbiosis [2] and belong to a small group of poorly characterized proteins from plant-associated bacteria that contain one or two autocleavage motifs known as DUF1521 (Schirrmeister et al. 2011). The amino acid sequence of a NopE-like protein in the L. mariae-josephae strain LmjC contains just one autocatalytic motif. This is unlike NopE1 and NopE2 proteins secreted by the T3SS of B. japonicum, that contain two motifs [3]. The autocleavage of LmjC NopE protein was analyzed after expression in E. coli and purification. Two protein fragments of the predicted sizes appeared in the presence of Ca2+, Cu2+, Cd2+, Zn2+ and Mn2+ cations. In contrast, autocleavage did not take place in the presence of Ni2+, Co2+ or Mg2+. Site-directed mutagenesis of the DUF1521 motif in LmjC NopE abolished self-cleavage in vitro. Symbiotic competence of a NopE- mutant with the L. mariae-josephae host was not affected. Possible roles of NopE are discussed.

Quorum Sensing is essential for an effective symbiosis in R. leguminosarum UPM791.

The implications of Quorum Sensing in the establishment of a successful symbiosis of Rhizobium leguminosarum bv. viciae (Rlv) with legume plants are discussed in this work. In order to analyze the significance and regulation of the production of AHL signal molecules, mutants deficient in each of the two QS systems present in Rlv UPM791 were constructed. A detailed analysis of the effect of these mutations on growth, AHL production, biofilm formation and symbiosis with pea, vetch and lentil plants has been carried out.

Native bradyrhizobia isolated from Lupinus mariae-josephae possess an essential T3SS for symbiosis

Analysis of the genome sequence of bradyrhizobia strains isolated from root nodules of Lupinus mariae-josephae revealed the presence of a type III secretion system (T3SS). Mutagenesis of ttsI gene that codes for the transcriptional activator (TtsI) resulted in the formation of white, non-fixing nodules in L. mariae-josephae. The T3SS cluster includes a gene coding for a NopE-like protein with an autocleavage motif. The NopE protein is an effector in the Bradyrhizobium-soybean symbiosis (Wenzel et al., 2010). The autocatalytic properties of the purified NopE-like protein have been studied.