929 resultados para Cardiomyopathy, Restrictive


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A partir de Buiter e Miller (1981), Obstfeld (1983), Sachs (1981), Svensson e Razin (1983) e alguns outros, a abordagem intertemporal da conta-corrente passou a receber atenção crescente da literatura. Desde então os estudos empíricos não são unânimes em atestar sua validade e, dessa forma, a evidência empírica tem sido mista. Mais recentemente, Corsetti e Konstantinou (2009) caracterizam empiricamente a dinâmica conjunta da conta-corrente, ativos e passivos externos a valor de mercado e produto líquido para os EUA no período pós Bretton Woods. Ao contrário da maioria das outras publicações, Corsetti e Konstantinou (2009) são pouco restritivos no que diz respeito às premissas. Neste trabalho buscou-se aplicar a mesma metodologia emprega por Corsetti e Konstantinou (2009) para analisar o equilíbrio externo do Brasil entre 1990 e 2014, período no qual diversos choques afetaram a economia brasileira. São identificados os componentes transitórios e permanentes para a dinâmica conjunta das quatro variáveis básicas da restrição intertemporal da economia, ou seja: Consumo, Produto Líquido, Ativos externos e Passivos externos. O presente trabalho sugere que existem evidências da validade da abordagem intertemporal da conta-corrente para o Brasil, mesmo a análise sendo feita em uma amostra em que estão presentes choques significantes que afetaram a economia brasileira.

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Brazil was frequently criticized for its interventionist and heavy financial regulation up until the 2008‐09 world financial crisis.  According to the neo‐liberal or pro‐market view that predominated in academic and financial circles during the early 2000s, economic development came together with financial deepening, which in its turn could only be achieved through financial liberalization and deregulation. The currency crises of the 1990s notwithstanding, by the mid‐2000s Brazil’s segmented financial market and its restrictive reserve and capital requirements were seen as a symbol of inefficiency and backwardness by most financial specialists.  To the luck of the Brazilian population, most of the advices of such specialists were ignored by the Brazilian authorities, so that, when the 2008 financial crisis hit the world economy, Brazil still had powerful and efficient instruments to deal with the problem.  The objective of this note is to present the mains aspects of the Brazilian financial regulation and how they helped the economy to deal with the consequences of 2008‐09 financial meltdown.

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O microcrédito tem sido uma ferramenta de combate à pobreza no mundo todo nas últimas décadas. A ampliação do acesso ao crédito àqueles que não podem recorrer ao sistema financeiro tradicional tem se constituído como uma via democrática de fomento à inclusão social através da geração de trabalho e renda. Os empréstimos realizados têm demonstrado efeitos benéficos sobre a comunidades de baixa renda, especialmente em relação às mulheres, pelo desencadeamento de um processo de empoderamento com efeitos em sua capacidade de auferir renda, melhorar sua autoestima e ampliar sua participação em espaços de tomada de decisão. No Brasil, as mulheres são a maioria dos tomadores de microcrédito e a justificativa para isso perpassa pelas dificuldades relativas ao mercado formal, a necessidade de complementação da renda familiar, o desejo de maior emancipação frente aos companheiros e a busca pela realização num pequeno empreendimento próprio. Em Fortaleza (CE), o Banco Palmas criou um projeto de empoderamento de gênero, focado em beneficiárias do Programa Bolsa Família, a partir da concessão de microcrédito. A presente dissertação teve como objetivo analisar as dimensões do processo de empoderamento alcançadas pelas mulheres participantes deste projeto, intitulado como projeto “ELAS”. A hipótese inicial era a de que a nova capacidade economicamente produtiva das entrevistadas modificaria sua realidade, colocando-as em um novo patamar frente a si mesmas e às suas famílias, proporcionando maior autonomia em suas decisões de consumo e independência financeira frente a seus maridos, além do aumento de seu bem-estar. Nesse caso, o microcrédito serviria como um fomentador do empoderamento individual feminino, hipótese comprovada neste estudo. Entretanto, notou-se que não houve um rompimento das relações de gênero no âmbito das famílias, fator perceptível principalmente pela não redistribuição das tarefas domiciliares, com impactos restritivos no empoderamento social dessas mulheres através da não participação em instâncias coletivas de tomada de decisão.

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The present objective study to inside identify the critical factors of success of the local family companies of a competitive boarding. For in such a way the same it understands the culture and the management of the family companies of success, identifies the essential areas of performance, it establishes the restrictive factors of the success, and analyzes the level of influence of the critical factors of success in the competitiveness of this type of company. In function of the subject little to be explored, and of this study to provide a general vision concerning the factors that take the family companies to get success, this research is explorer. On the other hand, for describing characteristic of the familiar companies in prominence in the local scene and for being worried about the practical performance, the same one also is descriptive. The sample in turn is the not-probabilist one of the intentional type, for accessibility. For operacionalization of the collection of data, the direct contact was used, being the composed instrument of research for variable as management, culture, critical factors of success and competitiveness. The study it evidences that in regards to the management and the culture of the family companies of success, some variable are turned aside from the standard of the conventional family companies cited by literature. Of general form in the familiar companies of success it has a bigger level of professionalization of the management. As for the value given to the knowledge, the study sample that the conventional family companies give little importance to it, in contrast of the family companies in prominence, who value of significant form the search for the knowledge. He is demonstrated despite the family companies of success, even so total are not professionalized, possess a bigger level of professionalization of the management, ratifying of certain forms the reason for which the majority develops the Strategical Planning formal periodically. In short, the results point 17 critical factors of success with respect to the family companies, in special factors as the product quality and services, and the use of the technology

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Introduction: Chagas Disease is a serious public health problem, with 5 million infected individuals in Brazil. Of these, approximately 30% develop chronic Chagas cardiomyopathy (CCC), where the main symptoms are fatigue and dyspnea. Objective: To correlate maximal exercise capacity with pulmonary function, inspiratory muscle strength and quality of life in patients with CCC. Methodology: Twelve individuals suffering from CCC were evaluated (7 men), with a mean age of 54.91± 8.60 years and the following inclusion criteria: functional class II and III according to the New York Heart Association (NYHA); left ventricle ejection fraction below 45%; clinical stability (> 3 months); symptom duration > 1 year, body mass index (BMI) < 35Kg/m2 and non-smokers or ex-smokers with a history of smoking <10 packs/day. All subjects were submitted to spirometry, manometer testing, maximal cardiopulmonary exercise testing (CPX) and a quality of life questionnaire (Minnesota). Results: A negative correlation was observed between VO2máx and MLHFQ scores (r=-0.626; p=0.03) and a positive association with MIP (r=0.713; p=0.009). Positive correlations were also recorded between MIP and spirometric variables [FEV1(r=0.825;p=0.001 ), FVC(r=0.66;p=0.01 and FEF25-75%(r=0.639;p=0.02)]. Conclusion: The present study demonstrated that in patients with CCC: VO2MAX is directly related to inspiratory muscle strength and quality of life, while deteriorating lung function is directly associated with respiratory muscle weakness

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The economic changes occurred in the 90s, with the restructuring and privatization of various sectors of the economy have led to a redefinition of the State role, assuming a position of regulator and supervisor of public services in place to direct its role as straight intervenor. It is through the regulatory agencies, autarchies with special legal personality under public law, that the Regulator State will act. In this context, the first objective of this research is to analyze the legality of easements imposed by entities of the Direct Administration and Regulatory Agencies, whose execution is delegated to legal persons of private law, being those public service companies or mixed-economy societies. This examination in question the limits of servitude as a restrictive institute of property rights, observing the principles of function, supremacy of the public interests over the private ones, legality and the separation of powers. Defend the property rights like a fundamental right and your insurance as determining factor of economic development and social justice. Use the procedure in use will be the historiccomparative procedure, in order to demonstrate the legality of the public act as a maximum attempt to preserve the balance between the expansion of public services in various sectors of the economy, and the preservation of property rights, through regulation

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The purpose of this dissertation is to analyze the role of Public Powers in the enforcement of fundamental social rights, according to the principle of prohibition to social regression. The Federal Constitution of Brazil, situated in a position normative hierarchical superior, disciplines the legal and political process of the country, determining how Public Powers (Legislative, Executive and Judiciary) should act to enforce fundamental rights (social). Thus, features a cast of fundamental rights that aim to ensure social justice, highlighting the concern to ensure social values aimed at reducing social inequalities. The will of the state should be prevented by controlling the constitutionality of measures which restrict fundamental social rights, assuming the principle of human dignity, pillar of Social and Democratic State of Right, a dual role in the brazilian legal system, acting as the presupposition of jurisdictional control of the constitutionality of restrictive acts and as supervisory of omission or insufficient action of the State in the fulfillment of their fundamental duties. The constitutional determinations remove from the legislator the option to create or not the law that prints effectiveness to the social rights, as well as from the Executive the option of to execute or not rules directed at realization of the constitutional parameters, and Judiciary to behave or not in accordance with the Constitution, being given to the Powers only the arbitrariness of "how" to do, so that all functions performed by public actors to use the Constitution as a repository of the foundational values of the collectivity. Any situation that does not conform the principle of proportionality in relation to the enforcement of fundamental rights, especially the social, represents an unacceptable social regression unconstitutional. The constitutional rules and principles postulated by the realization of the rights, freedoms and guarantees of the human person, acting the principle of prohibition to social regression to regulate a concrete situation, whenever it is intended to change, reducing or deleting, the content of a social right. This paper of limit of state action serves to provide to the society legal security and protection of trust, ensuring the core of every social right. This should be effected to be sheltered the existential minimum, as a guarantee of the inviolability of human life, respecting the constitutional will, not falling into social regression

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This work pursues to analyze the sanctions of restrictive nature, which are characterized by impeding the business of the contributor in debt. Such sanctions known as political sanctions, are truly understood as an indirect way of tax enforcement, liable to cause problems to the private entity in curtailing, the initiative freedom, opposing the Article 5°, item XIII and Article 170, single paragraph of CF/88. As the State gets the several means to assure the economic order effective performance, it is up to the State to restrain the economic power abuse that objects to the marketing domination, to the ending of competition, and arbitrary increasing of profits (CF Article 173, § 4ª.) Therefore, it depends on the state, besides maintaining the economic order, to ensure a fair distribution of tax burden and act under the command of the Democratic State of Law principles. In order to make the tax collection effective, specific in some cases, the administrative fiscal agent uses coercive, excessive, and institutional, in imposing sanctions which causes constraint, maculating the contributor s essential rights, that matters of the necessity to force the tax credit ending. The principle of the free initiative and free competition, which are intended to be analyzed in this study, comes from a constitutional context and it will be reviewed in its systematic relations and with another rules, in order to evidence, at the end, the occurrence of an intervention towards the economic order when the State makes do of political sanctions as a tool for the tax credit effectiveness, infringing the Tax and Constitutional principles

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Avaliou-se a cardiotoxicidade da doxorrubicina utilizando-se sete cães adultos, clinicamente normais, que receberam 30mg/m² de cloridrato de doxorrubicina (Adriblastina®) por via intravenosa, a cada 21 dias, durante 168 dias (grupo A), perfazendo dose cumulativa total de 240mg/m². em outros sete cães (grupo B) administraram-se 5ml de solução salina 0,9% estéril por via intravenosa, seguindo-se o esquema de aplicação proposto anteriormente. Os animais foram avaliados, periodicamente, por meio de exames ecocardiográficos em modo-M e bidimensional. Verificou-se aumento (P<0,01) no diâmetro e volume do ventrículo esquerdo, inicialmente em sístole e, posteriormente, em diástole, hipocinesia do septo interventricular e da parede livre do ventrículo esquerdo, reduções de aproximadamente 65% nas frações de encurtamento e de ejeção, além de aumento da separação do septo do ponto E do folheto anterior da válvula mitral nos animais do grupo A. As alterações cardíacas decorrentes do tratamento crônico com doxorrubicina foram semelhantes àquelas descritas em cães com cardiomiopatia dilatada, e os índices ecocardiográficos puderam ser utilizados no acompanhamento e na prevenção da cardiotoxicidade pelo quimioterápico.

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This study aims to problematize the history of mixed schools in Pará, from 1870 to 1901, highlighting women participation that helped to build them. The analytical focus of the research fell on the changes and the continuities of the mixed school in Pará. The object of analysis is the Paraense mixed schools, formed by women. The study also brings out arguments that the mixed school was set up in variable forms, concepts, times and spaces, in an overlapping with the inclusion of women in educational universe, either through education, professionalization or teaching in schools of girls and boys. The documentary sources privileged by the study are: the educational law, the newspapers, the government reports and the journals of education, which were examined in a confrontation between what was said and done. The evidential method helped the documentary reading revealed that, in small lines, the linkages built in the search for clues and signs of Paraense mixed schools was assembled with the participation of women, from the perception that historical knowledge is indirect, conjectural. Evidences indicated that the school for both sexes, legally established in the Province of Grão-Pará in 1870, gave the signals of the junction of girls and boys in school, at a time when the presence of women in education was suggested. Mutations related to the educational organization, with the introduction of mixed school in the following decade had a closer relationship with restrictive settings and more effective integration of women in that school. The inaccuracies of the Republican mixed school have revealed, through winding paths, that signal of contradictions between the modern discourse and conservative practices regarding this school, in communion with the expansion of the mixed school throughout the state, including in groups schools, observing the presence of effective women teachers in the regency of such schools and an expansion of students in relation to the equity between the sexes

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Due of industrial informatics several attempts have been done to develop notations and semantics, which are used for classifying and describing different kind of system behavior, particularly in the modeling phase. Such attempts provide the infrastructure to resolve some real problems of engineering and construct practical systems that aim at, mainly, to increase the productivity, quality, and security of the process. Despite the many studies that have attempted to develop friendly methods for industrial controller programming, they are still programmed by conventional trial-and-error methods and, in practice, there is little written documentation on these systems. The ideal solution would be to use a computational environment that allows industrial engineers to implement the system using high-level language and that follows international standards. Accordingly, this work proposes a methodology for plant and control modelling of the discrete event systems that include sequential, parallel and timed operations, using a formalism based on Statecharts, denominated Basic Statechart (BSC). The methodology also permits automatic procedures to validate and implement these systems. To validate our methodology, we presented two case studies with typical examples of the manufacturing sector. The first example shows a sequential control for a tagged machine, which is used to illustrated dependences between the devices of the plant. In the second example, we discuss more than one strategy for controlling a manufacturing cell. The model with no control has 72 states (distinct configurations) and, the model with sequential control generated 20 different states, but they only act in 8 distinct configurations. The model with parallel control generated 210 different states, but these 210 configurations act only in 26 distinct configurations, therefore, one strategy control less restrictive than previous. Lastly, we presented one example for highlight the modular characteristic of our methodology, which it is very important to maintenance of applications. In this example, the sensors for identifying pieces in the plant were removed. So, changes in the control model are needed to transmit the information of the input buffer sensor to the others positions of the cell

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Dados de rebanhos bovinos comerciais foram analisados com o objetivo de estimar as interações dos efeitos genéticos com o ambiente que podem influenciar a avaliação de características de crescimento em rebanhos de animais puros e cruzados. O conjunto de dados analisado foi obtido a partir de animais das raças Hereford, Nelore e seus cruzamentos. As características em estudo foram os pesos à desmama e ao sobreano dos animais. As análises estatísticas foram realizadas pelo método dos quadrados mínimos e o modelo proposto incluiu os efeitos de região, grupo de contemporâneos dentro de região, mês de nascimento e sexo do bezerro, os efeitos lineares e quadráticos para a idade do bezerro e idade da vaca ao parto, ambas analisadas dentro de sexo, e os efeitos de grupo genético e da interação grupo genético × região. de modo geral, o desempenho de todos os grupos genéticos foi influenciado pelo efeito de região. Além disso, observou-se tendência de que o aumento da proporção de genes zebuínos promoveu diminuição na diferença de desempenho entre as regiões. Todos os genótipos foram beneficiados no ambiente menos restritivo, o que indica a existência de interação genótipo-ambiente e comprova a importância de que sistemas de cruzamento sejam realizados de forma a manter a adaptação das matrizes e de seus produtos.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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No Rio Grande do Sul (RS), muitas áreas sob plantio direto apresentam elevada saturação por Al e baixa saturação por bases na camada de 0,10-0,20 m (subsuperfície), e isso pode diminuir a produção de grãos de culturas anuais. O objetivo do presente trabalho foi avaliar se a ocorrência de alta saturação por Al e baixa saturação por bases em subsuperfície (0,10-0,20 m), no plantio direto, pode representar um ambiente restritivo para a produção de culturas, bem como avaliar os modos de incorporação de calcário na correção da acidez do solo em subsuperfície. Para isso, foi realizado um experimento com os cultivos de soja (2005/ 2006), milho (2006/2007), trigo (2007) e soja (2007/2008), em um Latossolo Vermelho distrófico típico (Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA), 2006) de textura franco arenosa, há quatro anos sob plantio direto, no município de Tupanciretã (RS). Os seis tratamentos foram: sem revolvimento com ou sem calcário; lavração com ou sem calcário; e escarificação com ou sem calcário. Aos 24 meses após a aplicação dos tratamentos e nas camadas de 0-0,05, 0,05-0,10, 0,10-0,15, 0,15-0,20 e 0,20-0,30 m, foram avaliados os valores de pH-H2O, saturação por Al e por bases. Avaliou-se a produtividade de soja (2005/2006), milho (2006/2007), trigo (2007) e soja (2007/2008). A acidez do solo em subsuperfície não alterou a produtividade das culturas quando as propriedades de acidez na camada de 0-0,10 m estavam em níveis em que não se recomenda a aplicação de calcário, segundo a CQFSRS/SC (2004). A incorporação de calcário com aração foi o modo mais eficiente de corrigir a acidez em profundidade.