6-环己甲基取代S-DABO类化合物、其合成方法和用途

6-环己甲基取代S-DABO类化合物、其合成方法和用途，属药物技术领域。本发明涉及一种5-烷基-6-环己甲基-2-(烷基、环烷基、环烷基甲基、取代苯乙酮)硫尿嘧啶类化合物，该类化合物具有如(Ⅰ)通式：其中： R1为C1-3的烷基； R2＝C1-8的烷基、环烷基、环烷基甲基，如(Ⅱ)式：(其中，X＝OCH3，H， OH，卤素)。分别以氯甲基环己烷或环己基乙酸为原料制备β-酮酯，再与硫脲在醇钠催化下缩合关环制得关键中间体5-烷基-6-环己甲基硫尿嘧啶，最后通过S-烷基化反应引入C2-位侧链制备目标分子，合成方法简便易行，产物具有极其显著的抗HIV病毒活性和抗耐药性，可作为抗HIV药物候选物。

Studies on the toxicological effects of Asulox-40 and Emisan-6 to eggs and early life history stages of Sarotherodon mossambicus

Toxicological effects of Asulox-40 and Emisan-6 to eggs and early life history stages of Sarotherodon mossambicus were reported. 80% of egg hatching occurred in the controls, 1 p.p.m and 5 p.p.m concentrations of Asulox-40. 10 p.p.m. and 50 p.p.m. concentrations of the same toxicants had 70% and 60% hatchings while in Emisan-6 in the same concentrations the hatching were 70% and! 40%. In 100 p.p.m. concentration of both toxicants 20% incomplete hatching occurred. In Emisan-6 Lc 50 and Lc 100 values were recorded at 32 hand 96h respectively in 10 p.p.m. concentrations. In Asulox-40 the same values were recorded in 24h and 40h respectively at 50 p.p.m. concentration. The fish activity during the experimental period showed initial hyper activity. It was established that the Emisan-6 is more harmful to S. mossambicus than Asulox-40. The harmless concentrations of these chemicals were 1.2 p.p.m. for Asulox-40 and 0.6 p.p.m. for Emisan-6.

Isolation of Salmonella braenderup (6, 7:e, h:e, n, z (sub15)) from Mussel meat

A brief account is given of the morphology, biochemistry and serology of Salmonella braenderup isolated from mussel meat, obtained from fish markets in Calicut, India. Possible implications regarding human salmonellosis are also considered.

Przewalskin A: A new C-23 terpenoid with a 6/6/7 carbon ring skeleton from Salvia przewalskii maxim

Przewalskin A (1), a novel C-23 terpenoid with a 6/6/7 carbon ring skeleton, was isolated from Salvia przewalskii. Its structure was determined by comprehensive 1D NMR, 2D NMR, and MS spectroscopic analysis and subsequently confirmed by a single-crystal X

4-Benzyl-5-ethyl-2-(2-furylcarbonylmethylsulfanyl) pyrimidin-6(1H)-one

The title compound, C19H18N2O3S, shows favourable activity against HIV-1. The phenyl ring is twisted with respect to the pyrimidine ring by 61.56 (9)degrees. Intermolecular N-H center dot center dot center dot O and C-H center dot center dot center dot O

Induced breeding of Indian carps using Des Gly^10 [D-Ala^6] LHRH ethylamide

Details are given of a study conducted in order to determine the efficacy of Des Gly^10 [D-Ala^6] LHRH ethylamide in the induction of spawning in Cirrhinus mrigala and Labeo fimbriatus . Findings shows this LHRH analogue to be a promising substitute for the pituitary gland extract which is currently used. Further studies are required to standardize the dose and method of administration in the various cultivable species in India.

First bi-lateral consultation meeting on Gulf of Mannar ecosystem, Rameshwaram, India, 5-6 September, 2011

Status papers on resources, livelihoods and ecosystem approach to fisheries in the Gulf of Mannar(GoM) were presented.Five priority initiatives were agreed: collaborative effort in conservation and management of charismatic species (e.g. dugong),capacity building and training,education and awareness building, strengthening of data collection and sharing of information.

An illustrated key to the Malacostraca (Crustacea) of the northern Arabian Sea. Part 6: Decapoda anomura

The key deals with the Decapoda, Anomura of the northern Arabian Sea, belonging to 3 super-families, 10 families, 32 genera and 104 species. With few exceptions, each species is accompanied by illustrations of taxonomic importance; its first reporter is referenced, supplemented by a subsequent record from the area. Necessary schematic diagrams explaining terminologies are also included.

Fish products of 6 Asian countries

The paper gives an overview of the 11 main categories of fish products resulting from the survey in Brunei Darussalam, Indonesia, Malaysia, Philippines, Singapore and Thailand.

牛胚胎在BRL/mTCM199和HECM-6/mTCM199培养体系中发育潜能的探讨

将受精卵置于下列两种培养体系中进行体外培养:(1)Buffalo rat liver细胞与改进的TCM199培养液共同培养系统(BRL/mTCM199);(2)半确定培养液两步培养系统[无血清的金黄地鼠培养液与改进的TCM199培养液(HECM-6/mTCM199]。结果表明:后者的囊胚率(50%)明显高于前者的囊胚率(41%,P<0.01)。表明牛胚胎早期分裂可在无蛋白培养条件下进行,并且在此培养条件下有良好的后续发育能力。这可能与两步培养体系中葡萄糖和氨基酸浓度不同有关。

Hardfacing using supersonic laser depostion of stellite-6

The capability of manufacturing coatings is of central importance in engineering design. Many components require nowadays the application of additional layers, to enhance mechanical properties and protect against hostile environments. Supersonic Laser Deposition (SLD) is a novel coating method, based upon Cold Spray (CS) principles. In this technique the deposition velocities can be significantly lower than those required for effective bonding in CS applications. The addition of laser heat energy permits a change in the thermodynamic experience of impacting particles, thereby offering a greater opportunity for metallurgical bonding at lower velocities compared to the CS process technology. The work reported in this paper demonstrates the ability of the SLD process to deliver hard facing materials to engineering surfaces. Stellite-6 has been deposited on low carbon steel tubes over a range of process parameters, determining the appropriate target power and traverse speeds for coating deposition. Coating properties and parameters were examined to determine the main properties, micro-structure and processing cost. Their morphology was studied through optical microscopy, SEM and X-Ray Diffraction. The results have shown that SLD is capable of depositing Stellite-6, with enhanced properties compared to laser clad counterparts.

Seminario sobre ciencias básicas como prerequisito para la enseñanza de la oceanografía (1-2 octubre de 1962)- Seminario sobre biogeografía de los organismos marinos (3-6 octubre de 1962)

Por acuerdo del Seminario Latinoamericano sobre Estudios Oceanográficos realizado en la Universidad de Concepción, Chile, 20-25 noviembre de 1961, se recomendó la realización en Argentina de un Seminario sobre Biogeografía de Organismos Marinos, indicándose al Museo Argentino de Ciencias Naturales Bernardino Rivadavia como sede del mismo. Luego de varias conversaciones en Buenos Aires (Argentina), entre autoridades del Centro de Cooperación Científica para América Latina, del CONICET (Consejo Nacional de Investigaciones Científicas y Técnicas), del Servicio de Hidrografía Naval, del mencionado Museo y del Instituto de Biología Marina de Mar del Plata, se acordó realizar los seminarios en éste último instituto del 1 al 6 octubre de 1962. Del 1 al 2 de octubre, se realizó el Seminario sobre Ciencias Básicas como prerrequisito para la Enseñanza de la Oceanografía, pero los documentos no fueron incluídos en este Boletín. Del 3 al 6 de octubre, tuvo lugar el Seminario sobre Biogeografía de Organismos Marinos, con la participación de investigadores de: Brasil, Colombia, Costa Rica, Chile, Mexico, Perú, Uruguay, Venezuela y de Argentina, y se incluyeron los siguientes trabajos publicados: Joly, A. - Extensao da flora marinha no sul do Brasil- nota preliminar; Etcheverry Daza, H. - Distribución geográfica de las algas del Pacífico; Diaz-Piferrer, M. - Biogeografía de las algas marinas tropicales de la costa Atlántica de America, Resumen,; Kuhneman, O. - Importancia de la vegetación en biogeografía marina; Boschi, E.E. - Los peneidos de Brasil, Uruguay y Argentina; Bernasconi, I. - Distribución geográfica de los equinoideos y asteroideos de la extremidad austral de Sudamérica; Szidat, L. - La parasitología como ciencia auxiliar para la biogeografía de organismos marinos; López, R.B. - Problemas de la distribución geográfica de los peces marinos sudamericanos; Ximénez, I. - Estudio preliminar de la distribución geográfica actual de los pinípedos en América Latina; Balech, E. - La división zonal en biología marina y su nomenclatura; Stuardo, J. - Distribución de los moluscos marinos litorales en Latinoamérica; Boltovskoy, E. - Provincias zoogeográficas de América del Sur y su sector Antártico según los foraminíferos bentónicos; Rioja, E. - Caracteres de la biogeografía marina de México y de Centro América; Balech, E. - Caracteres biogeográficos de la región de Argentina y Uruguay; Vannucci, M. - Zoogeografía marinha do Brasil.

基于部分线粒体细胞色素氧化酶亚基Ⅰ(mtCOI)DNA 序列的6种蝙蝠(翼手目:蝙蝠科)的分子系统进化关系

对贵州5种蝙蝠科蝙蝠的部分线粒体细胞色素氧化酶亚基Ⅰ DNA序列进行了测定,并结合从Genbank获得的爪哇伏翼的相应序列,以Pteropus dasymallus,P.scapulatus,Rousettus aegyptiacus为外群,运用贝叶斯法(Bayesian),最大似然法(Maximum Likelihood,ML)分析了这6种蝙蝠科蝙蝠的分子系统进化关系.结果表明:在贝叶斯,ML树中,这6种蝙蝠科的蝙蝠可分为3个分支:亚洲长翼蝠是第1个独立出来的分支;白腹管鼻蝠是继亚洲长翼蝠之后第2个分离出来的分支;第3个分支又分为两支,一支由大鼠耳蝠和小鼠耳蝠组成,另一支由南蝠和爪哇伏翼组成,支持将这4种蝙蝠同归于蝙蝠亚科的结论,从一定程度上否定了鼠耳蝠属和管鼻蝠亚科之间的姐妹类群关系,也不支持将鼠耳属提升为亚科.