954 resultados para Assis, Machado de, 1839-1908. Dom Casmurro


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Pós-graduação em História - FCHS

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Background. Melatonin is a free radical scavenger with important actions in the study of renal ischemia and reperfusion (I/R). This study evaluated possible renal protection of high doses of melatonin in an experimental model of I/R in which rats were submitted to acute hyperglycemia under anesthesia with isoflurane.Method. Forty-four male Wistar rats, weighing more than 300 g, were randomly divided into 5 groups: G1, sham (n = 10); G2, melatonin (n = 10; 50 mg.kg(-1)); G3, hyperglycemia (n = 9; glucose 2.5 g.kg(-1)); G4, hyperglycemia/melatonin (n = 10; 2.5 g.kg(-1) glucose + melatonin 50 mg.kg(-1)); and G5, I/R (n = 5). In all groups, anesthesia was induced with 4% isoflurane and maintained with 1.5% to 2.0% isoflurane. Intraperitoneal injection of melatonin (G1, G4), glucose (G3, G4), or saline (G1, G5) was performed 40 minutes before left renal ischemia. Serum plasma values for creatinine and glucose were determined at baseline (M1), immediately following reperfusion (M2), and 24 hours after completion of the experiment (M3). Histological analysis was performed to evaluate tubular necrosis (0-5).Results. Serum glucose was higher at M2 in the groups supplemented with glucose, hyperglycemia (356.00 +/- 107.83), and hyperglycemia/melatonin (445.3 +/- 148.32). Creatinine values were higher at T3 (P = .0001) for I/R (3.6 +/- 0.37), hyperglycemia/melatonin (3.9 +/- 0.46), and hyperglycemia (3.71 +/- 0.69) and lower in the sham (0.79 +/- 0.16) and melatonin (2.01 +/- 1.01) groups, P < .05. Histology showed no necrosis injury in the G1, lesion grade 2 in the G2, and severe acute tubular necrosis in the G3: (grade 4), G4: (grade 5) and G5: (grade 4) groups (P < .0001).Discussion. Melatonin protected the kidneys submitted to I/R in rats without hyperglycemia; however, this did not occur when the I/R lesion was associated with hyperglycemia.Conclusions. Due to its antioxidant and antiapoptotic action, melatonin was able to mitigate, but not prevent acute tubular necrosis in rats with hyperglycemia under anesthesia by isoflurane.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Estudos Literários - FCLAR

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This coursework aims the dialogical analysis of discourses that constitute the statements given by Josué Machado, a journalist in the magazine Língua Portuguesa, publishing Segmento. The research aims to observe the ideologies that mark the statements in question, regarding to the values of the standard language and the quality of a text. Methodologically, we seek the understanding of how the discourse of analyzed chronic , publicized during the stated period from number 32 to number 70, dialogues with purist discourse and the discourse of sociolinguistics. The methodological theoretical support covers Bakhtinian studies of the discourse. The results show that the subject who enunciates in the analyzed chronicles shows in his speech a purist voice, in which the discourse of clarity takes emphasis. The values that define his discourse about language are those that prevail in the sphere of journalism

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O presente trabalho constitui uma tentativa de traçar os caminhos do magistério no plano real/histórico através do resgate da imagem dos docentes retratados na literatura brasileira, além de auxiliar alunos e professores de cursos de licenciatura a entender melhor os processos históricos. Ao longo de nossa história diversos escritores se propuseram a retratar o professor em suas obras, tais como: Machado de Assis (1840), com Conto de Escola, Raul Dávila Pompéia (1888) em O Ateneu, Oswald de Andrade (1926) em Memórias Sentimentais de João Miramar, Sylvia Orthof (1980) com a crônica Bicho Carpinteiro, Ziraldo (1995) em Uma professora muito Maluquinha e Thalita Rebouças (2006), em Fala sério, Professor! E é a partir dessas obras que ocorre uma reflexão sobre a imagem que os profissionais da educação transmitem/transmitiram para a sociedade, através do olhar dos artistas literários. Além de influenciar a visão daqueles que lêem suas obras, os escritores transpõem em seus textos elementos que nos permitem reviver o paradigma por eles vivenciado, fazendo da literatura um instrumento para o resgate da história.

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It is known that the urban environment modifies the energy balance between the surface and the atmosphere, causing changes in temperature, relative humidity, among other things, opening the way for studies aimed at urban climatology. Based on the theme of urban climate, this research focuses on the city of Assis, located west of São Paulo. The generation of urban climate is a result of various factors, among which stand out: the use and different land use, the thermodynamic properties of buildings, number of buildings in the urban, socioeconomic activities, etc.. In general, this increases the temperature and reducing relative humidity, providing thermal discomfort. The rural environment is used for comparison studies to this theme by presenting different characteristics in relation to the structure, morphology and urban functionality. The main objective of this study is to determine the characteristics of temperature and humidity environments with the habits and occupations of the different soils in winter, at night, one inserted into the urban fabric of Assis and the other in the rural environment, to verify for evidence of changes in climatic elements because of urbanization. To collect the data will be used mini automatic weather stations that record data on temperature and humidity. For analysis of the results will be made between the data obtained in the city and the countryside, developing graphics application using Excel to tabulate the data. It was found that there were differences in the thermo-hygrometric data collection points, showing a specific urban climate in the city of Assis

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Este trabalho apresenta um estudo e levantamento dos potenciais turísticos da cidade de Álvares Machado-SP, bem como alguns benefícios que essa prática poderá trazer. Através desse levantamento, objetivamos propor alternativas para que o município aproveite melhor seus pontos turísticos, além de reforçar o sentimento dos munícipes pela cultura e história de formação da comuna. Dessa maneira, pautados pelo diagnóstico turístico, apresentamos na câmara dos vereadores a proposta da criação de uma Divisão de Turismo na prefeitura de Álvares Machado-SP, além do processo de tombamento histórico do conjunto de prédios da extinta FEPASA, onde será encaminhado para o CONDEPHAAT

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The lack of proper planning in intervention works of runoff water on rural properties and rural public roads leads to economic damage and loss of environmental quality. The impact of the action without technical base is soil erosion, siltation of water sources, loss of the quality and availability of water, invalidating areas for cultivation and livestock. The conservation of headwaters requires beyond regeneration of the environmental characteristics the repair and management of the degraded watercourse in order to control erosion. This graduate work in Environmental Engineering from Universidade Estadual Paulista Julio de Mesquita Filho - UNESP Presidente Prudente proposes a headwater recuperation and management in rural area of Álvares Machado municipality, São Paulo State, through the method of deep drainage applied to the case of a rural road near the outcrop of water. This technique consists in the installation of draining structures in sub-areas of the road surface, or sub-gutter and/or in the platform border in order to conduct the underground flow of water and reduce the loss of sediment in water flow. Therefore, was performed a historic study of use and occupation of land in the municipality of Álvares Machado, portraying transformations of the landscape caused by human action. Geology, geomorphology, pedology and hydrogeology data were collected from the study area in order to establish the conditions that led into the current situation of degradation and formulate an effective intervention strategy for civil works

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Johann Heinrich Pestalozzi revolucionou a sociedade no século XVIII, com suas ideias educativas. Com uma educação humanitária, tendo como princípio básico a benevolência na formação de seus educandos, Pestalozzi posicionava-se a favor da generalização da instrução, para que esta fosse concebida também aos pobres. Desse modo, Pestalozzi funda escolas que recolhem órfãos, mendigos e pequenos ladrões. Nessas entidades havia uma formação geral e profissional. Para Pestalozzi, as crianças precisam de limites, porém em sua Pedagogia não havia punições, sugerindo uma educação não repressiva, contrapondo com as ideias da época. Esta concepção de educação baseada na repressão ainda continua em parte do século XIX, porém outro educador, assim como Pestalozzi, não concorda com os métodos punitivos. Giovanni Melchiorre Bosco, mais conhecido como Dom Bosco, engloba em suas obras educativas três princípios, que compõem o tripé básico de sua educação: razão, religião e amorevolezza, formando o Sistema Preventivo, ideal de sua arte educativa. Com a intenção de desenvolver esse Sistema, Dom Bosco cria os oratórios. Nestes espaços, crianças e jovens de classe baixa, são acolhidos para estudar, brincar e rezar. Mais tarde, as escolas profissionalizantes são incluídas nessa educação. Desse modo, tornam-se interessantes estas duas perspectivas educacionais, separadas pelo tempo histórico de seus idealizadores, com propostas pedagógicas pautadas em bases preventivas ao invés de repressivas. Neste ponto, pretende-se investigar se há realmente alguma relação entre a Pedagogia de Pestalozzi e o Sistema Preventivo de Dom Bosco. Indaga-se ainda se existe alguma influência direta e/ou indireta do primeiro sobre o segundo. Assim, este trabalho visa analisar comparativamente a pedagogia de Pestalozzi e o Sistema Preventivo de Dom Bosco... (Resumo completo, clicar acesso eletrônico abaixo)

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Environmental diagnosis fits in analysis social-spatial organization insofar it contributes to understanding past and present aspects of how a territory works as well as enables the creation of statements for future ordainment. In this context, the present study aims at contributing with data for creating recovery and environmental preservation projects for the basin of Macacos‟ stream‟s headwaters, located in the north of Álvares Machado county in São Paulo state. To achieve this purpose, the main characteristics and existing uses in the basin have been analyzed and its main environmental problems were identified in the data and information collected in journals, field work and interviews with dwellers from the interested area and local government authorities. On this way, a diagnosis of the environmental state of the studied area was performed considering its specific issues regarding the natural and physical process as well as human influences. From the analysis carried out it was possible to identify environmental impacts on different levels resulting from the conflictuous relation between uses and occupations and the natural dynamics of the studied basin.

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This work analyzes the importance of public policies in the process of urban-environmental preservation of the Alvares Machado city at state of Sao Paulo in Brazil, where priority was given to questions related to cultural heritage. Adopting the concept of territory as base to understand the complexities in the city, this work clarifies and contextualizes the historical heritage legislation through the Master Plan and the City Statute. The work also focuses on the contribution of the geographer toward studies related to urban-environmental planning.

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When handling soil conservation practices isn’t applied correctly, they cause problems at the level of structure, cohesion and fertility in soils and lack of water availability. In the case of this monograph, conducted in a rural property located at Álvares Machado City, identified that most areas are intended for use activities of beef cattle and dairy and subsistence agriculture, which historically addition to withdraw native flora, resulting in problems such as compaction and increase soil exposure to climatic agents, generating a serious frame of erosion problems. In the case of water from rainfall, the soil exposed, causes the “splash” effect and therefore when it becomes runoff carries the spalled particles mainly for low land areas. Without the vegetation, especially trees or shrubs species, the velocity of runoff increases, initiating the appearance of furrows, which consequently may become a kind of ravine erosion and gully, which makes invalid any area in your surroundings... (Complete abstract click electronic access below)

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Pós-graduação em Letras - FCLAS