Peri-implant bone loss of dental implants with platform-switching design after 5 years of loading: a cross-sectional study

OBJECTIVE The aim of this cross-sectional study was to estimate bone loss of implants with platform-switching design and analyze possible risk indicators after 5 years of loading in a multi-centered private practice network. METHOD AND MATERIALS Peri-implant bone loss was measured radiographically as the distance from the implant shoulder to the mesial and distal alveolar crest, respectively. Risk factor analysis for marginal bone loss included type of implant prosthetic treatment concept and dental status of the opposite arch. RESULTS A total of 316 implants in 98 study patients after 5 years of loading were examined. The overall mean value for radiographic bone loss was 1.02 mm (SD ± 1.25 mm, 95% CI 0.90- 1.14). Correlation analyses indicated a strong association of peri-implant bone loss > 2 mm for removable implant-retained prostheses with an odds ratio of 53.8. CONCLUSION The 5-year-results of the study show clinically acceptable values of mean bone loss after 5 years of loading. Implant-supported removable prostheses seem to be a strong co-factor for extensive bone level changes compared to fixed reconstructions. However, these results have to be considered for evaluation of the included special cohort under private dental office conditions.

Code-switching: a touchstone of models of bilingual language production

The goal of the present thesis was to investigate the production of code-switched utterances in bilinguals’ speech production. This study investigates the availability of grammatical-category information during bilingual language processing. The specific aim is to examine the processes involved in the production of Persian-English bilingual compound verbs (BCVs). A bilingual compound verb is formed when the nominal constituent of a compound verb is replaced by an item from the other language. In the present cases of BCVs the nominal constituents are replaced by a verb from the other language. The main question addressed is how a lexical element corresponding to a verb node can be placed in a slot that corresponds to a noun lemma. This study also investigates how the production of BCVs might be captured within a model of BCVs and how such a model may be integrated within incremental network models of speech production. In the present study, both naturalistic and experimental data were used to investigate the processes involved in the production of BCVs. In the first part of the present study, I collected 2298 minutes of a popular Iranian TV program and found 962 code-switched utterances. In 83 (8%) of the switched cases, insertions occurred within the Persian compound verb structure, hence, resulting in BCVs. As to the second part of my work, a picture-word interference experiment was conducted. This study addressed whether in the case of the production of Persian-English BCVs, English verbs compete with the corresponding Persian compound verbs as a whole, or whether English verbs compete with the nominal constituents of Persian compound verbs only. Persian-English bilinguals named pictures depicting actions in 4 conditions in Persian (L1). In condition 1, participants named pictures of action using the whole Persian compound verb in the context of its English equivalent distractor verb. In condition 2, only the nominal constituent was produced in the presence of the light verb of the target Persian compound verb and in the context of a semantically closely related English distractor verb. In condition 3, the whole Persian compound verb was produced in the context of a semantically unrelated English distractor verb. In condition 4, only the nominal constituent was produced in the presence of the light verb of the target Persian compound verb and in the context of a semantically unrelated English distractor verb. The main effect of linguistic unit was significant by participants and items. Naming latencies were longer in the nominal linguistic unit compared to the compound verb (CV) linguistic unit. That is, participants were slower to produce the nominal constituent of compound verbs in the context of a semantically closely related English distractor verb compared to producing the whole compound verbs in the context of a semantically closely related English distractor verb. The three-way interaction between version of the experiment (CV and nominal versions), linguistic unit (nominal and CV linguistic units), and relation (semantically related and unrelated distractor words) was significant by participants. In both versions, naming latencies were longer in the semantically related nominal linguistic unit compared to the response latencies in the semantically related CV linguistic unit. In both versions, naming latencies were longer in the semantically related nominal linguistic unit compared to response latencies in the semantically unrelated nominal linguistic unit. Both the analysis of the naturalistic data and the results of the experiment revealed that in the case of the production of the nominal constituent of BCVs, a verb from the other language may compete with a noun from the base language, suggesting that grammatical category does not necessarily provide a constraint on lexical access during the production of the nominal constituent of BCVs. There was a minimal context in condition 2 (the nominal linguistic unit) in which the nominal constituent was produced in the presence of its corresponding light verb. The results suggest that generating words within a context may not guarantee that the effect of grammatical class becomes available. A model is proposed in order to characterize the processes involved in the production of BCVs. Implications for models of bilingual language production are discussed.

Characterization of template switching and recombination during Moloney murine leukemia virus replication

Retroviruses uniquely co-package two copies of their genomic RNA within each virion. The two copies are used as templates for synthesis of the proviral DNA during the process of reverse transcription. Two template switches are required to complete retroviral DNA synthesis by the retroviral enzyme, reverse transcriptase. With two RNA genomes present in the virion, reverse transcriptase can make template switches utilizing only one of the RNA templates (intramolecular) or utilizing both RNA templates (intermolecular) during the process of reverse transcription. The results presented in this study show that during a single cycle of Moloney murine leukemia virus replication, both nonrecombinant and recombinant proviruses predominantly underwent intramolecular minus- and plus-strand transfers during the process of reverse transcription. This is the first study to examine the nature of the required template switches occurring during MLV replication and these results support the previous findings for SNV, and the hypothesis that the required template switches are ordered events. This study also determined rates for deletion and a rate of recombination for a single cycle of MLV replication. The rates reported here are comparable to the rates previously reported for both SNV and MLV. ^

The relationship between leadership practices and a medication safety regime

Errors in healthcare are commonplace and have significant impact on mortality, morbidity, and costs. Other high-risk industries are credited with strong safety records. These successes are due in part to a strong, committed organizational culture and their leadership. A consistent pattern of effective leadership behaviors; creating change, establishing a vision and strategic actions, and enabling and inspiring the organization's members to act, is present in these high-risk industries. This research examined the relationship between leadership practices and a medication safety regime. The hypothesis is strong leadership practices have a positive relationship with the degree of sophistication of a medication safety program (safety performance). Leadership was used as a surrogate for organizational culture and was measured in this research through the Kouzes and Posner's Leadership Practices Inventory. The Institute of Medicine's 14 Selected Strategies to Improve Medication Safety was used to measure the development of a medication safety regime. Leadership practices towards safety were assessed by surveying 2,478 critical care Registered Nurses in the greater Houston area. A response rate of 19% was achieved. Thirteen hospitals participated in the medication safety regime assessment. Data from 386 RN respondents from 53 institutions provided an overall description of unit (ICU) and organization (hospital) leader's practices towards safety. There is some recognition of the medical error problem and that leaders exhibit moderate levels of leadership practices to promote safety. There were no differences noted in unit and hospital leaders' behaviors, with the exception that unit leaders promote change and enable staff to act more often than hospital leaders. There were no statistically significant relationships between overall leadership, or individual leadership practices and the organization's safety performance. There was a significant relationship between leadership and safety performance when other factors in organizational culture were considered. Teaching and Magnet hospitals also exhibited stronger behaviors towards safety. Organizational culture, as measured by academic affiliation and Magnet recognition, is strongly related to safety performance as measured by the degree of development of a medication safety regime. ^

OS Planos Municipais de Educaçao no Tocantins : Arqueologia dos processos de construçao e perspectivas de regime de colaboraçao e da gestao democrática

O trabalho apresenta resultados de pesquisa acerca das políticas de educaçao no Brasil, do princípio regime de colaboraçao e da gestao da educaçao, apresentando, neste momento, aspectos da trajetória sociopolítica da elaboraçao ou adequaçao dos Planos Municipais de Educaçao (PMEs), deflagrada em 2013 pelo MEC/SASE, com as possibilidades de efetivaçao do regime de colaboraçao e da gestao democrática. Sua abordagem é qualitativa, de caráter teórico-empírico e exploratório, abarcando a documentaçao relativa aos PMEs dos Municípios. No Tocantins, até o início do ano de 2014, um georreferenciamento demonstra que dos 139 Municípios, apenas seis elaboraram seus PMEs. Neste contexto, predomina a visao de administraçao municipal restrita às suas instituiçoes escolares e ao tempo de sua gestao, sem relaçao ou articulaçao com metas nacionais comuns com vistas à materializaçao do Sistema Nacional de Educaçao. Deste processo, destaca-se o significativo movimento sociopolítico em torno do planejamento da educaçao no século XXI, enfrentado o desafio de definir o objetivo comum da educaçao brasileira. Entretanto, há ideias que merecem ser investigadas, como a sua concepçao de gestao e planejamento e as formas de colaboraçao estabelecidas

OS Planos Municipais de Educaçao no Tocantins : Arqueologia dos processos de construçao e perspectivas de regime de colaboraçao e da gestao democrática

O trabalho apresenta resultados de pesquisa acerca das políticas de educaçao no Brasil, do princípio regime de colaboraçao e da gestao da educaçao, apresentando, neste momento, aspectos da trajetória sociopolítica da elaboraçao ou adequaçao dos Planos Municipais de Educaçao (PMEs), deflagrada em 2013 pelo MEC/SASE, com as possibilidades de efetivaçao do regime de colaboraçao e da gestao democrática. Sua abordagem é qualitativa, de caráter teórico-empírico e exploratório, abarcando a documentaçao relativa aos PMEs dos Municípios. No Tocantins, até o início do ano de 2014, um georreferenciamento demonstra que dos 139 Municípios, apenas seis elaboraram seus PMEs. Neste contexto, predomina a visao de administraçao municipal restrita às suas instituiçoes escolares e ao tempo de sua gestao, sem relaçao ou articulaçao com metas nacionais comuns com vistas à materializaçao do Sistema Nacional de Educaçao. Deste processo, destaca-se o significativo movimento sociopolítico em torno do planejamento da educaçao no século XXI, enfrentado o desafio de definir o objetivo comum da educaçao brasileira. Entretanto, há ideias que merecem ser investigadas, como a sua concepçao de gestao e planejamento e as formas de colaboraçao estabelecidas

OS Planos Municipais de Educaçao no Tocantins : Arqueologia dos processos de construçao e perspectivas de regime de colaboraçao e da gestao democrática

O trabalho apresenta resultados de pesquisa acerca das políticas de educaçao no Brasil, do princípio regime de colaboraçao e da gestao da educaçao, apresentando, neste momento, aspectos da trajetória sociopolítica da elaboraçao ou adequaçao dos Planos Municipais de Educaçao (PMEs), deflagrada em 2013 pelo MEC/SASE, com as possibilidades de efetivaçao do regime de colaboraçao e da gestao democrática. Sua abordagem é qualitativa, de caráter teórico-empírico e exploratório, abarcando a documentaçao relativa aos PMEs dos Municípios. No Tocantins, até o início do ano de 2014, um georreferenciamento demonstra que dos 139 Municípios, apenas seis elaboraram seus PMEs. Neste contexto, predomina a visao de administraçao municipal restrita às suas instituiçoes escolares e ao tempo de sua gestao, sem relaçao ou articulaçao com metas nacionais comuns com vistas à materializaçao do Sistema Nacional de Educaçao. Deste processo, destaca-se o significativo movimento sociopolítico em torno do planejamento da educaçao no século XXI, enfrentado o desafio de definir o objetivo comum da educaçao brasileira. Entretanto, há ideias que merecem ser investigadas, como a sua concepçao de gestao e planejamento e as formas de colaboraçao estabelecidas