Indicadores de depressão e de declínio cognitivo em idosos institucionalizados: um estudo de caso

This case study objectified investigating the symptomatology prevalence for depression (DP) and cognitive decline (CD) on institutionalized elderly’s; verifying the existence of correlations between DP and CD with age, gender and scholarity; and analyzing the possible correlations between symptomatology for DP and CD. For the realization of this research were selected, in two Elderly’s Long-Permanence Institutions (ELPIs), 24 subjects, which were classified according to gender, scholarity and age group. To verify the occurrence of CD, the Mini Mental State Examination (MMSE) was applied and, for the incidence of DP, the Geriatric Depression Scale (GDS) was applied. The data were tabulated and descriptively analyzed. For the study of the relations between quantitative variables, the Pearson correlation test was utilized and also the Spearmann test when necessary; for the comparison between two independent groups, the Student's t-test was utilized; for the verification of the association between gender, scholarity, DP and CD indicatives, the Pearson's X2 test and, due to theoretical restriction, the Fisher's exact test were utilized. The level of 5% probability was adopted for the rejection of nullity's hypothesis on all the tests. The research demonstrated that 50% of the research' subjects presented DP indicatives and 54.2% presented CD indicatives. Associations between: gender and DP (p = 0.414), gender and CD (p = 0.219), scholarity and CD (p = 0.527) were not observed. Positive regular correlation was verified between age and DP (r = 0.557; p = 0.005) and negative regular correlation was verified between DP and CD (r = -0.406; p = 0.049). The data suggest that DP might be a reaction to CD perceived by the subject. However, the hypothesis that indicates DP as a risk factor for CD and DM cannot be overruled, which suggests the importance of monitoring and treating depressive episodes on elderly populations.

Kant, a democracia e o liberalismo

The article argues that Kant cannot be considered a democratic thinker, given not only his rejection to the ancient form of democracy (based on the institution of the assembly), but also the modern form of democracy (based on the principle of representation), however a liberal thinker, supporter of the limited State and the individual rigths.

Effect of hemolysis on canine, bovine and earn e serum chemistry

Hemolysis is the main cause of biochemical analysis rejection's in veterinary laboratories, however the relative error caused by hemoglobin on serum biochemical profile has not been properly established on several species. In order to establish criteria for aproval and rejection of hemolyzed samples for serum biochemical tests, the hypothesis that hemolysis causes biochemical changes in canine, cattle and horses and that laboratorial error depends on species and hemolysis degree was tested. Thus, non-hemolyzed serum was contaminated with crescent hemoglobin levels and using commercial routine reagents, the serum concentrations of uric acid, albumin, cholesterol, triglycerides and urea, besides the activity of ALT, AST, CK and GUT were quantified in triplicate samples. The relative error was calculated by the comparison between hemolyzed and non-hemolyzed samples. Hemolys is did not cause significant error on the albumin determination in all three species, AST in canine and cattle, ALT in horses, UK and cholesterol in canine. There was a linear increase on uric acid levels in horses and cattle, triglycerides in all three species. A linear increase in serum urea in all species serum, UK and cholesterol in cattle and cholesterol in horses was observed. Serum AST activity on equine serum and ALT in cattle decreased linearly due to hemolysis. It was concluded that hemolysis promotes changes in canine, equine and bovine serum chemistry profile, however the laboratorial error not necessarily compromises the diagnosis in all cases, because the changes depends on species and degree of in vitro hemolysis.

Comissionamento de turbinas hidráulicas: ensaios de faixa operativa, índex, test e rejeição de carga

With growing electricty demand, the importance of generation through hydropower, a renewable energy source, it’s of great importance. This demand derives from the country’s growth, as well as events that will occur in the coming years. The commission has a crucial role before the entry into operation of hydroelectric plant, sice, ensures a good operation of hydraulic and electrical systems, as well as the safety of the installation. This paper is a case study, commissioning in a PCH in especially the most important tests, such as range operation, índex tes and load rejection. In these trials we can get a Idea of the actual behavior of the unit, as well as future operation maneuvers, and evidence of real efficiency

Um Estudo da modelagem matemática na educação matemática e seu potencial para o desenvolvimento do pensamento crítico

The implementation of mathematical modeling curricula represents a great challenge, both for teachers and students, since it escapes the traditional teaching methodology, i.e. when the teacher speaks to his/her students. This work presents, at least, one possible way of implementing mathematical modeling inside the classroom, and how this way encourage critical thinking in students. I see mathematical modeling as an opportunity to minimize student's rejection and increase their interest for mathematics, promoting their competencies to give points of scene in every day situations. The history of mathematics shows that mathematical modeling had developed since almost the beginning of human live, when men needed to solve problems that arose in the course of his life. Mathematics has become more and more abstract, but it is important to recall what was originated it. In this way, it is possible to make this subject matter more meaningful to students. I will make an introduction of mathematical modeling, presenting some important definitions. Based on this framework, I will present a classroom instruction understand on a 7 th grade classroom by myself. With this in instruction I sustain the idea that mathematical modeling has, in fact, a great potential to improve the quality of mathematics teaching. I also sustain that, the development of critical thinking, as a competence, way be achieved with it

Basquetebol X temas transversais: a produção de material didático audiovisual para a Educação Física escolar

This study aimed, first, produce a kind of educational materials in audiovisual format, to the Physical Education, addressing the Transversal Themes in view of the basketball. The themes chosen were Cultural Plurality, addressing the basketball in a wheelchair, and Labor and Consumer Affairs, addressing the marketing and exploitation of labor force that the company is Nike. There is no doubt the importance of media production in contemporary society, as one of its main languages, but of little relevance in the school environment, especially in the area of Physical Education. In a second phase aimed at evaluating the feasibility of this material both as a teaching strategy, such as content of learning lessons. The evaluation was made through a discussion in the form of focus groups with 10 students from 9 th grade of elementary school. The results showed that despite an initial rejection of the material as a teaching strategy because of the history that Physical Education has for several years, students were open to new ways of learning. Since the results on the material, such as learning content, showed that the videos were able to address and the Transversal Themes and meet the need for procedural content with the proposed activities. With this, we realize that students are willing to discuss matters that are not always addressed, but now, with the creation of national curriculum standards should be reflected in the classroom

Avaliação da apoptose e resposta Th17 em modelo murino de esporotricose

Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR

The essential role of annexin A1 mimetic peptide in the skin allograft survival

Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection.Studies have demonstrated the anti-infl ammatory effects of the annexin A1 (AnxA1) in the regulationof transmigration and apoptosis of leucocytes. In the present study, an experimental skin allograftmodel was used to evaluate a potential protective effect of AnxA1 in transplantation survival. Micewere used for the skin allograft model and pharmacological treatments were carried out using eitherthe AnxA1 mimetic peptide Ac2-26, with or without cyclosporine A (CsA), starting 3 days beforesurgery until rejection. Graft survival, skin histopathology, leucocyte transmigration and expressionof AnxA1 and AnxA5 post-transplantation were analysed. Pharmacological treatment with Ac2-26increased skin allograft survival related with inhibition of neutrophil transmigration and inductionof apoptos is, thereby reducing the tissue damage compared with control animals. Moreover, AnxA1and AnxA5 expression increased after Ac2-26 treatment in neutrophils. Interestingly, thecombination of Ac2-26 and cyclosporine A showed similar survival of transplants when compared withthe cyclosporine A group, which could be attributed to a synergistic effect of both drugs. Investigationsin vitro revealed that cyclosporine A inhibited extracellular-signal-regulated kinase (ERK) phosphory-lation induced by Ac2-26 in neutrophils. Overall, the results suggest that AnxA1 has an essential role inaugmenting the survival of skin allograft, mainly owing to inhibition of neutrophil transmigration andenhancement of apoptosis. This effect may lead to the development of new therapeutic approachesrelevant to transplant rejection.

Optical filters and resonant cavities based on di-ureasil organic–inorganic hybrids

Sol–gel derived poly(oxyethylene)/siloxane organic–inorganic di-ureasil hybrids containing different amounts (20–60% mol) of methacrylic acid (McOH) modified zirconium oxo-clusters (Zr-OMc) were processed as thin films and transparent and shape controlled monoliths. Laser direct writing was used to create channel waveguides, Bragg gratings, Fabry–Perot cavities and optical filters. The resulting Fabry–Perot optical cavity displays a free spectral range of 16.55 GHz and a fringe intensity contrast of 5.35 dB. Optical rejection values between 6.7 and 10.4 dB were obtained by varying the amount of the Zr-OMc oxo-clusters.

Liberação de componentes do extrato de Casearia sylvestris Swartz empregando membranas de látex natural como suporte

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos do FK-506 na regeneração de nervos após neurorrafia láteo-terminal: estudo em ratos

Pós-graduação em Bases Gerais da Cirurgia - FMB

A leitura como construção de conhecimento e de sentidos que conferem poder

As a literature’s teacher, I’ve performed a search during three years devoted to the reader’s formation. Through this research, which resulted in my master's dissertation (FERREIRA, 2003), I’ve tried to diagnose, from 1998 to 2000, which were the previous concepts of young people belonging to prestigious classes that have led them to the rejection of reading. I’ve choose, based on the diagnosis, to develop a work guided by the reception’s aesthetics that aloud them to review both of these concepts, to expand the horizons of their expectations.

A revisão das antinomias na psicologia: do racionalismo cientificista ao estruturalismo

In this essay, we sustain the idea that structuralist thinking is part of spontaneous criticism against the reductionisms that surround psychology. We depart from the radical split-up between the scientific viewpoint and that of metaphysics, expressed in the end-19th century scientific psychology projects. Next, we highlight the importance of the structuralist perspective in the review of the antinomic relations between the subjective and objective, operated at the heart of psychology throughout the 20th century. We show that the rejection of unilineal causality in favor of network causality curbed the advancement of unilateral or reductionist theories in psychology. Moreover, we consider the idea of structure as a point of convergence between psychology and philosophy. More than its explanatory nature, the notion of structure reveals an epistemological register capable of re-approximating psychology to the relativization of the ideal of scientific neutrality. The importance of structuralist thinking in psychology makes us consider the history of psychological knowledge as a type of research that belongs to cultural history.

The effect of CPP-ACP and Nd:YAG laser on the bond strength of softened dentin

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Diferentes esquemas de indução para transplante renal com doador vivo

Abstract Introduction: Indications for induction therapy is not consensual in living donors. Objective: The objective of this study was compare no induction with thymoglobulin and basiliximab induction in the incidence of acute rejection in kidney transplantation with living donor. Methods: We select all cases of renal transplantation with living donor performed in Hospital das Clínicas de Botucatu da UNESP during the period of January 2010 to December 2013. The group was divided by the type of medication used for induction. Results: A total of 90 patients were evaluated. There were no differences in baseline characteristics of age and underlying disease. The rate of biopsy-proven acute rejection was higher in the group without induction (42.9%) compared to basiliximab group (20%) and Thymoglobulin (16.7%), p = 0.04. The rejection by compatibility shows that the identical had the lower rejection rate (10%). The haploidentical group without induction had the highest rejection rates (53.3%). In all distinct group the rejection rates were similar with basiliximab or Thymoglobulin, p = NS. The use of induction therapy was associated independently with a lower risk of rejection (OR = 0.32 CI: 0.11 to 0.93, p = 0.036). There were no differences in renal function at 6 months and patient survival and graft in the three groups. Discussion: The haploidentical patients without induction were those with higher rates of acute rejection. The group of patients induced with Thymoglobulin had a higher immunological risk, however showed low rates of rejection. Conclusion: The use of induction therapy resulted in lower rates of rejection in transplantation with living donor.