993 resultados para Cooperativa Tritícola Mista Alto Jacuí.
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[ES] A pesar de que diferentes trabajos se han esforzado en identificar las variables que pueden estar en la base del alto rendimiento deportivo, no existe acuerdo todavía acerca de cuáles pueden ser verdaderamente las más relevantes. El presente trabajo de carácter exploratorio pretende comprobar la posible existencia de diferencias significativas a nivel psicológico, tomando como referencia algunas de las pruebas que habitualmente utilizan los psicólogos del deporte (POMS, CPRD, BREQ,...).
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[ES] Los objetivos del presente estudio son: 1) Describir los niveles de resiliencia en entrenadores de atletismo de alto rendimiento; 2) determinar los niveles de fiabilidad de los datos obtenidos con la muestra seleccionada; 3) comparar los resultados obtenidos con estudios precedentes. Se administró una adaptación de la entrevista para entrenadores de Ruiz (2004) y la adaptación al castellano de la escala de Resiliencia de Wagnield y Young (1993).
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Reperibile direttamente alla pagina http://www.artechhouse.com/default.asp?frame=book.asp&book=978-0-89006-989-9&Country=&Continent=EU&State=#sample
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Memoria de Licenciatura (Tesina) defendida en la Facultad de Geografía e Historia de la Universidad de Las Palmas de Gran Canaria el 22 de febrero de 1995. Calificación: Sobresaliente por unanimidad.
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Programa de Doctorado en Investigación en Biomedicina. Grupo de Investigación en Rendimiento Humano, Actividad Física y Salud.
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The effector function of natural killer (NK) cells is regulated by activating and inhibitory receptors, termed killer immunoglobulin-like receptors (KIRs). In haploidentical T-cell depleted transplantation the donor/recipient KIR mismatch significantly impacts on NK-mediated tumor cell killing, particularly in acute myeloid leukaemia (AML). Thirty-four high risk AML patients entered a phase I-II study of adoptive NK-cell based immunotherapy and were screened for the availability of one haploidentical KIR ligand mismatched donor. Thirteen of them resulted as having one suitable donor. NK cells were enriched from steady-state leukaphereses by using a double-step immunomagnetic separation system, consisting in depletion of CD3+ T cells followed by positive selection of CD56+ NK cells. CD56+ cells were enriched from 7,70% (1,26-11,70) to 93,50% (66,41-99,20) (median recovery 53,05% (30,97-72,85), median T-depletion 3,03 log (2,15-4,52) viability >92%) and their citotoxic activity was inalterate. All patients (4 progressions, 1 partial remission and 8 complete remissions) received NK cell infusion which was preceeded by immunosuppressive chemotherapy (fludarabine and cyclophosphamide) and followed by interleukin 2 injections. The median number of reinfused NK cells was 2,74x10(e)6/kg(1,11-5,00) and contamining CD3+ T cells were always less than 1x10(e)5/kg. The procedure was well-tolerated and no significant toxicity, including GvHD, related to NK cell infusion was observed. The donor NK cells were demonstrated in 5/10 patients. Among the 8 patients in complete remission 5 patients are stable after 18, 15, 4, 2 months of follow-up. Three other patients relapsed after 2 and 7 months. The patient in partial remission obtained a complete remission, which lasted for 6 months. The 4 patients with active/progressive disease showed the persistence of disease. This clinical observation may be correlated with in vitro studies, indicating that AML cells are capable to induce NK cell apoptosis in a dose-depend manner. In summery, a two-step enrichment of CD56+ NK cells allows the collection of a suitable number of target cells to be used as adoptive immunotherapy in AML patients. Infusion of NK cells is feasible and safe and adoptively transferred NK cells can be detected after infusion.