Implementação de metodologias BIM na Direção de Engenharia de Barragens da EDP: casos de estudo de projeto de estruturas em obras hidroelétricas

Dissertação de mestrado integrado em Engenharia Civil

A novel hanging spherical drop system for the generation of cellular spheroids and high throughput combinatorial drug screening

We propose a novel hanging spherical drop system for anchoring arrays of droplets of cell suspension based on the use of biomimetic superhydrophobic flat substrates, with controlled positional adhesion and minimum contact with a solid substrate. By facing down the platform, it was possible to generate independent spheroid bodies in a high throughput manner, in order to mimic in vivo tumour models on the lab-on-chip scale. To validate this system for drug screening purposes, the toxicity of the anti-cancer drug doxorubicin in cell spheroids was tested and compared to cells in 2D culture. The advantages presented by this platform, such as feasibility of the system and the ability to control the size uniformity of the spheroid, emphasize its potential to be used as a new low cost toolbox for high-throughput drug screening and in cell or tissue engineering.

O hospital da misericórdia de Penafiel (1600-1850)

Tese de Doutoramento em História - Especialidade de Idade Moderna

O reforço da democracia local no âmbito da reforma da administração autárquica

Dissertação de mestrado em Direito das Autarquias Locais

Definition of multibody system

This chapter presents a general view of multibody system concept and definition by describing the main features associated with spatial systems. The mechanical components, which can be modeled as rigid or flexible, are constrained by kinematic pair of different types. Additionally, the bodies can be actuated upon by force elements and external forces due to interaction with environment. This chapter also presents some examples of application of multibody systems that can include automotive vehicles, mechanisms, robots and biomechanical systems.

Angular velocity and acceleration

In this chapter, a complete characterization of the angular velocity and angular acceleration for rigid bodies in spatial multibody systems are presented. For both cases, local and global formulations are described taking into account the advantages of using Euler parameters. In this process, the transformation between global and local components of the angular velocity and time derivative of the Euler parameters are analyzed and discussed in this chapter.

Force elements and reaction forces

"Series title: Springerbriefs in applied sciences and technology, ISSN 2191-530X"

Avaliação da toxicidade das águas do rio Cubatão (Norte) - Joinville, SC, com base em ensaios ecotoxicológicos com Daphnia magna

Dissertação de mestrado em Ecologia

Dissipative contact force models

"Series: Solid mechanics and its applications, vol. 226"

Prospecção de ocorrências filonianas do tipo LCT nas formações metassedimentares entre Boticas e Montalegre (N de Portugal)

Dissertação de mestrado em Geologia (área de especialização em Valorização de Recursos Geológicos)

Modelo de gestão integrada dos contratos públicos eletrónicos orientados ao valor público

Tese de Doutoramento em Tecnologias e Sistemas de Informação.

To determine if the ‘NIMBY’ phenomenon explains the slow progress of wind farm development or do institutional factors need to be taken in to consideration?

The threats posed by climate change are placing governments under increasing pressure to meet electricity demand from low carbon sources. Wind energy has been has been identified as one of the main technologies to help in meeting these demands. The public in general favour wind energy yet proposed targets for generation capacity lag behind proposed goals. The N IM B Y phenomenon has been suggested as one of the reasons why we are behind our wind generation capacity targets. It is a common mistake to take general support for granted and expect the public to support developments when confronted with them in their local area. In many cases it is not unheard of that governing bodies whether social, political, regulatory, environmental, or cultural can overrule general public support and halt developments. Motives to halt developments will vary depending on the institutional body involved. The problem with the term N IM B Y is that it is too basic a term to describe the broad spectrum of complex motives that various institutions including the public may have against a development. This research focuses on a case study where the developer had major problems with the local county council and its wind energy policies when he was erecting a wind turbine despite having gained planning permission. A survey questionnaire was also used as part o f the research to seek the perception a rural community had on wind energy. The research findings and results are discussed with respect to the literature review highlighting a general public support for wind energy and the influence institutional bodies have over the progress of developments.

О потенциальной эне ргии гравитационного взаимодействия материальных тел

შრომაში განხილულია ორი, m1 და m2 მასათა მფლობელი, ერთმანეთისაგან R მანძილით დაშორებული მატერიალური სხეულის (მ.ს.) გრავიტაციული ურთიერთქმედება, როგორც მათი „ვარდნა“ საერთო სიმძიმის ცენტრის მიმართ.

О взаимодействии виртуальных кварков (в.к.) и материальных тел

შრომაში გრავიტაციული, ინერციული და გლუონური პროცესები წარმოდგენილია, როგორც მატერიალური სხეულების (მ.ს.) და ვირტუალური კვარკების (ვ.კ.) მიერ ვაკუუმში შექმნილი ერთგვაროვანი ძალური, არა ფარადეი-მაქსველის ტიპის ფონური გრავიტაციული ველის (ფგვ) ურთიერთქმედების გამოვლინება.

Mechanische Charakterisierung von Konstruktionskeramik im oberflächennahen Bereich

Engineering ceramics, indentation methods, crack-resistance, Rayleigh waves, acoustic microscopy, machining parameters, green ceramic bodies, ultrasonic contact impedance, acoustic impedance, residual stress