869 resultados para small to medium sized enterprises
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Greyish brown sediment with clasts ranging from small to medium in size. The clast shape ranges from sub-angular to rounded. Lineations and rotation structures are common throughout the sample. Comet structures can also be seen. Grain crushing and stacking are also present throughout the sample.
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Brown sediment with clasts ranging from small to medium in size. Clast shape ranges from angular to rounded. Rotation structures and grain crushing can be seen throughout the sample. Lineations and minor amounts of grain stacking can also be seen.
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Greyish brown sediment with clasts ranging from small to medium in size. Clast shape ranges from sub-angular to rounded. Lineations and rotation structures can be seen scattered throughout the sample. Comet structures can also be seen in certain areas of the sample. Minor amounts of grain crushing and stacking can also be seen.
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This sample is brown in colour. It appears to be clay rich. Clasts range from small to medium in size and sub-angular to sub-rounded in shape. A few lineations can be seen. There may also be darker areas of organic material.
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Brown sediment with clasts ranging from small to medium in size. Clast shape ranges from angular to sub-rounded. Rotation structures and comet structures are commonly seen throughout this sample. Lineations are also common. Minor amounts of grain stacking can also be seen. Some grains appear to be fractured and/or weathered.
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Brown sediment with inclusions of a clay rich domain. Clasts range from small to medium in size and angular to sub-rounded in shape. Lineations can be commonly seen throughout the sample, along with water escape structures in the clay rich domain. Rotation structures, comet structures, and grain crushing are also present.
Propuesta de mejoramiento de la política de inventarios de la empresa Wholesale and Retail Place LLC
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Wholesale and Retail place LLC, es una empresa que nace en el año 2012 en la ciudad de Carteret, Nueva Jersey dedicada a la comercialización y distribución de ropa para mujer colombiana en Estados Unidos. De esta manera, la problemática abordada en este proyecto será la influencia de la política de inventarios en el desempeño de la empresa. A partir de esto, se plantea realizar un mejoramiento de la política de gestión de inventarios, recurso que procure cambiar el modelo operativo de negocio mediante un enfoque a la transición, desde una pequeña hasta una mediana empresa, con énfasis en la perdurabilidad y sostenibilidad de la compañía.
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Consider the statement "this project should cost X and has risk of Y". Such statements are used daily in industry as the basis for making decisions. The work reported here is part of a study aimed at providing a rational and pragmatic basis for such statements. Of particular interest are predictions made in the requirements and early phases of projects. A preliminary model has been constructed using Bayesian Belief Networks and in support of this, a programme to collect and study data during the execution of various software development projects commenced in May 2002. The data collection programme is undertaken under the constraints of a commercial industrial regime of multiple concurrent small to medium scale software development projects. Guided by pragmatism, the work is predicated on the use of data that can be collected readily by project managers; including expert judgements, effort, elapsed times and metrics collected within each project.
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In recent years, exciting progress has been made towards unravelling the complex intraovarian control mechanisms that, in concert with systemic signals, coordinate the recruitment, selection and growth of follicles from the primordial stage through to ovulation and corpus luteum formation. A plethora of growth factors, many belonging to the transforming growth factor-beta (TGF-beta) superfamily, are expressed by ovarian somatic cells and oocytes in a developmental, stage-related manner and function as intraovarian regulators of folliculogenesis. Two such factors, bone morphogenetic proteins, RMP-4 and BMP-7, are expressed by ovarian stromal cells and/or theca cells and have recently been implicated as positive regulators of the primordial-to-primary follicle transition. In contrast, evidence indicates a negative role for anti-Mullerian hormone (AMH, also known as Mullerian-inhibiting substance) of pre-granulosa/granulosa cell origin in this key event and subsequent progression to the antral stage. Two other TGF-beta superfamily members, growth and differentiation factor-9 (GDF-9) and BMP-15 (also known as GDF-9B) are expressed in an oocyte-specific manner from a very early stage and play key roles in promoting follicle growth beyond the primary stage; mice with null mutations in the gdf-9 gene or ewes with inactivating mutations in gdf-9 or bmp-15 genes are infertile with follicle development arrested at the primary stage. Studies on later stages of follicle development indicate positive roles for granulosa cell-derived activin, BMP-2, -5 and -6, theca cell-derived BMP-2, -4 and -7 and oocyte-derived BMP-6 in promoting granulosa cell proliferation, follicle survival and prevention of premature luteinization and/or atresia. Concomitantly, activin, TGF-beta and several BMPs may exert paracrine actions on theca cells to attenuate LH-dependent androgen production in small to medium-size antral follicles. Dominant follicle selection in monovular species may depend on differential FSH sensitivity amongst a growing cohort of small antral follicles. Changes in intrafollicular activins, GDF-9, AMH and several BMPs may contribute to this selection process by modulating both FSH- and IGF-dependent signalling pathways in granulosa cells. Activin may also play a positive role in oocyte maturation and acquisition of developmental competence. in addition to its endocrine role to suppress FSH secretion, increased output of inhibin by the selected dominant follicle(s) may upregulate LH-induced androgen secretion that is required to sustain a high level of oestradiol secretion during the pre-ovulatory phase. Advances in our understanding of intraovarian regulatory mechanisms should facilitate the development of new approaches for monitoring and manipulating ovarian function and improving fertility in domesticated livestock, endangered species and man.
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Members of the transforming growth factor-beta (TGF-beta) superfamily have wide-ranging influences on many tissue and organ systems including the ovary. Two recently discovered TGF-beta superfamily members, growth/differentiation factor-9 (GDF-9) and bone morphogenetic protein-15 (BMP-15; also designated as GDF-9B) are expressed in an oocyte-specific manner from a very early stage and play a key role in promoting follicle growth beyond the primary stage. Follicle growth to the small antral stage does not require gonadotrophins but appears to be driven by local autocrine/paracrine signals from both somatic cell types (granulosa and theca) and from the oocyte. TGF-beta superfamily members expressed by follicular cells and implicated in this phase of follicle development include TGF-beta, activin, GDF-9/9B and several BMPs. Acquisition of follicle-stimulating hormone (FSH) responsiveness is a pre-requisite for growth beyond the small antral stage and evidence indicates an autocrine role for granulosa-derived activin in promoting granulosa cell proliferation, FSH receptor expression and aromatase activity. Indeed, some of the effects of FSH on granulosa cells may be mediated by endogenous activin. At the same time, activin may act on theca cells to attenuate luteinizing hormone (LH)-dependent androgen production in small to medium-size antral follicles. Dominant follicle selection appears to depend on differential FSH sensitivity amongst a growing cohort of small antral follicles. Activin may contribute to this selection process by sensitizing those follicles with the highest "activin tone" to FSH. Production of inhibin, like oestradiol, increases in selected dominant follicles, in an FSH- and insulin-like growth factor-dependent manner and may exert a paracrine action on theca cells to upregulate LH-induced secretion of androgen, an essential requirement for further oestradiol secretion by the pre-ovulatory follicle. Like activin, BMP-4 and -7 (mostly from theca), and BMP-6 (mostly from oocyte), can enhance oestradiol and inhibin secretion by bovine granulosa cells while suppressing progesterone secretion; this suggests a functional role in delaying follicle luteinization and/or atresia. Follistatin, on the other hand, may favor luteinization and/or atresia by bio-neutralizing intrafollicular activin and BMPs. Activin receptors are expressed by the oocyte and activin may have a further intrafollicular role in the terminal stages of follicle differentiation to promote oocyte maturation and developmental competence. In a reciprocal manner, oocyte-derived GDF-9/9B may act on the surrounding cumulus granulosa cells to attenuate oestradiol output and promote progesterone and hyaluronic acid production, mucification and cumulus expansion.(C) 2003 Elsevier Science B.V. All rights reserved.
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This paper provides a comprehensive quantitative review of high quality randomized controlled trials of psychological therapies for anxiety disorders in children and young people. Using a systematic search for randomized controlled trials which included a control condition and reported data suitable for meta-analysis, 55 studies were included. Eligible studies were rated for methodological quality and outcome data were extracted and analyzed using standard methods. Trial quality was variable, many studies were underpowered and adverse effects were rarely assessed; however, quality ratings were higher for more recently published studies. Most trials evaluated cognitive behavior therapy or behavior therapy and most recruited both children and adolescents. Psychological therapy for anxiety in children and young people was moderately effective overall, but effect sizes were small to medium when psychological therapy was compared to an active control condition. The effect size for non-CBT interventions was not significant. Parental involvement in therapy was not associated with differential effectiveness. Treatment targeted at specific anxiety disorders, individual psychotherapy, and psychotherapy with older children and adolescents had effect sizes which were larger than effect sizes for treatments targeting a range of anxiety disorders, group psychotherapy, and psychotherapy with younger children. Few studies included an effective follow-up. Future studies should follow CONSORT reporting standards, be adequately powered, and assess follow-up. Research trials are unlikely to address all important clinical questions around treatment delivery. Thus, careful assessment and formulation will remain an essential part of successful psychological treatment for anxiety in children and young people.
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O propósito primeiro desta dissertação foi o de mostrar, por meio de um estudo de caso, o da ACEPLAC, a aplicação do conceito de motivação como fator de criatividade e incremento de produção, em empresas de médio porte, sustentado por um modelo de gestão e de projetos de recompensa. Buscou-se justificar tal modelo pela observação sistemática dos esforços de trabalho, que se mostraram capazes de manter a motivação organizacional, apesar de sua volatilidade e voluntariedade. O método visava a trazer a experiência no campo concreto para o campo do conhecimento. Para isto, dividiu-se o longo processo em passos distintos, em que a obtenção de um arcabouço teórico sobre o complexo fenômeno que representa a motivação para o trabalho revelou-se o inequívoco ponto de partida. O estudo das várias características desse fenômeno e das inúmeras contribuições apresentadas desde Elton Mayo e Mary Follet até os dias atuais permitiu a construção de instrumental seguro para a análise crítica da realidade observada. Fez-se a opção de desenvolver a análise por meio do estudo de caso selecionado, uma vez que se pretendia ligar as abordagens teóricas à prática de modelos eficazes. O objetivo foi sinalizar para executivos e gerentes de empresas de médio porte aspectos relevantes para sua constituição e operacionalização, criando, assim, um panorama sobre a temática capaz de gerar novas alternativas para a tomada de decisão relativa ao assunto. Esse modelo é significativo porque conseguiu reduzir os aspectos voláteis e maximizar a voluntariedade dos empregados. O referido caso é rico em experiências, decisões e exemplos que podem ser adaptados e levados a outras empresas do mesmo porte. A análise criteriosa de todo o material de pesquisa levantado possibilitou a confirmação da afirmativa inicial, a qual priorizava a motivação como fator de criatividade e incremento de produção nas empresas de médio porte. Essas conclusões culminaram com a implantação do referido modelo, em maio de 1994, na Acesita Placas S/A - ACEPLAC.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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O objetivo deste trabalho foi avaliar a temperatura basal, a soma térmica acumulada em diferentes fases fenológicas, a duração das fenofases, a produtividade e a sazonalidade do ciclo de uma cultivar de nectarina e de 14 cultivares de pêssego, entre 2006 e 2009. As fases fenológicas consideradas foram: poda-brotação; brotação-florescimento, da gema inchada até a flor aberta; florescimento-frutificação, da queda das pétalas até o fruto médio; e maturação. As temperaturas basais mínimas obtidas foram: poda-brotação, 8°C, independentemente das cultivares avaliadas; brotação-florescimento, 10°C, com exceção de 'Cascata 968', que necessitou de Tb de 8°C; florescimento-frutificação, 12°C, exceto 'Oro Azteca', que necessitou de Tb de 14°C; maturação, 14°C, com exceção de 'Sunblaze', 'Diamante Mejorado' e 'Precocinho', com Tb de 12°C. Para a maioria das cultivares, as temperaturas basais máximas foram de 30, 34, 34 e 28ºC, nas fases poda-brotação, brotação-florescimento, florescimento-frutificação e maturação, respectivamente. 'Turmalina', 'Marli' e 'Tropic Beauty' apresentaram produtividade média de 3.945,0, 3.969,3 e 3.954,0 kg ha-1, em 2009, respectivamente, enquanto a nectarineira 'Sunblaze' produziu em torno de 3.900 kg ha-1 em 2008 e 2009. As cultivares diferiram quanto ao ciclo total e quanto às somas térmicas acumuladas que variaram, respectivamente, de 245 dias e 1.881,4 graus-dia em 'Oro Azteca', a 144 dias e 1.455,7 graus-dia em 'Precocinho'.
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The aim of this study was the seasonal characterization of the morphology, sedimentology and hydrodynamic of the Açu, Cavalos and Conchas estuaries. These estuaries are inserted in a semi-arid climate area and form the mouth of the hydrographic basin of the Piranhas-Açu river, that represent the discharge of the largest watershed in the state. They are embedded in an environment consisting of a fluvial-marine floodplain, mangrove ecosystem, sandbanks, fields of dunes, spits and sandy beaches. Adjacent to the natural units are the main local socioeconomic activities (oil industry, salt industry, shrimp farming, fishing and tourism) are dependent on this river and its conservation. The environmental monitoring is necessary because it is an area under constant action of coastal processes and at high risk of oil spill. The acquisition and interpretation of hydrodynamic, sonographic and sediment data was conducted in two campaigns, dry season (2010) and rainy season (2011), using respectively the current profiler ADCP Doppler effect, the side-scan sonar and Van Veen sampler. In these estuaries: Açu, Cavalos and Conchas were identified the following types of bedforms: flatbed and Dunes 2-D and 3-D (small to medium size), generated at lower flow regime (Froude number <1). Structures such as ripples were observed in the Açu estuary mouth. The higher values of flow discharge and velocity were recorded in the Açu estuary (434,992 m³.s-¹ and 0,554 m.s-¹). In rainy season, despite the record of highest values of discharge and flow velocities at the mouth, the energy rates upstream did not differ much from the data of the dry season. However, in all estuaries were recorded an increase in speed and flow, with reservation to the flow in the Açu estuary and flow at the mouth of the Conchas estuary. Sediment grain sizes tend to increase towards the mouth of the estuary and these ranged from very fine sand to very coarse sand, medium sand fraction being the most recurrent. Based on the data acquired and analyzed, the estuaries Açu, Cavalos and Conchas are classified as mixed , dominated by waves and tides. According to their morphology, they are classified as estuaries constructed by bar and according to the classification by salinity, estuaries Conchas and Cavalos were ranked as hypersaline estuaries, and Açu as hypersaline and vertically well mixed type C