Ionomer based blend as water vapor barrier material for organic device encapsulation

Blends of poly (ethylene-co-methacrylic acid) (PEMA) and poly (vinyl alcohol-co-ethylene) (EVOH) were studied for encapsulating Schottky structured organic devices. A calcium degradation test was used to determine water vapor transmission rates and to determine the moisture barrier performance of neat and blend films. Moisture barrier analysis for the neat and blend compositions was discussed concerning the interactions in the blend, diffusivity of water molecules through the unit cell systems, and the occupiable free volumes available in the unit cells using molecular dynamics simulations. The experimental results of water vapor permeation were correlated with diffusion behavior predicted from molecular dynamics simulations results. The effectiveness of the blend as a suitable barrier material in increasing the lifetime of an encapsulated Schottky structured organic device was determined.

Molecular Basis for the Differential Quinolone Susceptibility of Mycobacterial DNA Gyrase

DNA gyrase is a type II topoisomerase that catalyzes the introduction of negative supercoils in the genomes of eubacteria. Fluoroquinolones (FQs), successful as drugs clinically, target the enzyme to trap the gyrase-DNA complex, leading to the accumulation of double-strand breaks in the genome. Mycobacteria are less susceptible to commonly used FQs. However, an 8-methoxy-substituted FQ, moxifloxacin (MFX), is a potent antimycobacterial, and a higher susceptibility of mycobacterial gyrase to MFX has been demonstrated. Although several models explain the mechanism of FQ action and gyrase-DNA-FQ interaction, the basis for the differential susceptibility of mycobacterial gyrase to various FQs is not understood. We have addressed the basis of the differential susceptibility of the gyrase and revisited the mode of action of FQs. We demonstrate that FQs bind both Escherichia coli and Mycobacterium tuberculosis gyrases in the absence of DNA and that the addition of DNA enhances the drug binding. The FQs bind primarily to the GyrA subunit of mycobacterial gyrase, while in E. coli holoenzyme is the target. The binding of MFX to GyrA of M. tuberculosis correlates with its effectiveness as a better inhibitor of the enzyme and its efficacy in cell killing.

In situ formation of silver nanowire networks on paper

Simple, universally adaptable techniques for fabricating conductive patterns are required to translate laboratory-scale innovations into low-cost solutions for the developing world. Silver nanostructures have emerged as attractive candidates for forming such conductive patterns. We report here the in situ formation of conductive silver-nanowire networks on paper, thereby eliminating the need for either cost-intensive ink formulation or substrate preparation or complex post-deposition sintering steps. Reminiscent of the photographic process of `salt printing', a desktop office printer was used to deposit desired patterns of silver bromide on paper, which were subsequently exposed to light and then immersed in a photographic developer. Percolating silver nanowire networks that conformally coated the paper fibres were formed after 10 min of exposure to light from a commercial halogen lamp. Thus, conductive and patterned films with sheet resistances of the order of 4 Omega/rectangle can be easily formed by combining two widely used processes - inkjet printing and photographic development.

Flux Transport Dynamos: From Kinematics to Dynamics

Over the past several decades, Flux-Transport Dynamo (FTD) models have emerged as a popular paradigm for explaining the cyclic nature of solar magnetic activity. Their defining characteristic is the key role played by the mean meridional circulation in transporting magnetic flux and thereby regulating the cycle period. Most FTD models also incorporate the so-called Babcock-Leighton (BL) mechanism in which the mean poloidal field is produced by the emergence and subsequent dispersal of bipolar active regions. This feature is well grounded in solar observations and provides a means for assimilating observed surface flows and fields into the models in order to forecast future solar activity, to identify model biases, and to clarify the underlying physical processes. Furthermore, interpreting historical sunspot records within the context of FTD models can potentially provide insight into why cycle features such as amplitude and duration vary and what causes extreme events such as Grand Minima. Though they are generally robust in a modeling sense and make good contact with observed cycle features, FTD models rely on input physics that is only partially constrained by observation and that neglects the subtleties of convective transport, convective field generation, and nonlinear feedbacks. Here we review the formulation and application of FTD models and assess our current understanding of the input physics based largely on complementary 3D MHD simulations of solar convection, dynamo action, and flux emergence.

Multiple oligomeric structures of a bacterial small heat shock protein

Small heat shock proteins are ubiquitous molecular chaperones that form the first line of defence against the detrimental effects of cellular stress. Under conditions of stress they undergo drastic conformational rearrangements in order to bind to misfolded substrate proteins and prevent cellular protein aggregation. Owing to the dynamic nature of small heat shock protein oligomers, elucidating the structural basis of chaperone action and oligomerization still remains a challenge. In order to understand the organization of sHSP oligomers, we have determined crystal structures of a small heat shock protein from Salmonella typhimurium in a dimeric form and two higher oligomeric forms: an 18-mer and a 24-mer. Though the core dimer structure is conserved in all the forms, structural heterogeneity arises due to variation in the terminal regions.

Semi-insulating layer for novel high voltage polysilicon thin film transistors

This work describes the deposition and characterisation of semi-insulating oxygen-doped silicon films for the development of high voltage polycrystalline silicon (poly-Si) circuitry on glass. The performance of a novel poly-Si High Voltage Thin Film Transistor (HVTFT) structure, incorporating a layer of semi-insulating material, has been investigated using a two dimensional device simulator. The semi-insulating layer increases the operating voltage of the HVTFT structure by linearising the potential distribution in the device offset region. A glass compatible semi-insulating layer, suitable for HVTFT applications, has been deposited by the Plasma Enhanced Chemical Vapour Deposition (PECVD) technique from silane (SiH4), nitrous oxide (N2O) and helium (He) gas mixtures. The as-deposited films are furnace annealed at 600°C which is the maximum process temperature. By varying the N2O/SiH4 ratio the conductivity of the annealed films can be accurately controlled up to a maximum of around 10-7 Ω-1cm-1. Helium dilution of the reactant gases improves both film uniformity and reproducibility. Raman analysis shows the as-deposited and annealed films to be completely amorphous. A model for the microstructure of these Semi-Insulating Amorphous Oxygen-Doped Silicon (SIAOS) films is proposed to explain the observed physical and electrical properties.

Los actos intrínsecamente malos en Veritatis Splendor

Resumen: El autor se propone recordar el sentido verdadero de la doctrina de los actos intrínsecamente malos y el marco conceptual desde el que es interpretada. Para precisar el lugar fundamental de la perspectiva desde la cual se reflexiona acerca del acto moral considera las implicancias de la así llamada “perspectiva de la tercera persona” y del proporcionalismo, que asumen un punto de vista exterior al acto mismo, y la reafirmación que VS hace de dicha doctrina, en la perspectiva más propia para la apreciación de los actos humanos desde el punto de vista moral: la perspectiva de la persona que actúa, denominada “perspectiva de la primera persona”, que pone de relieve el carácter intencional de las acciones humanas. En ese marco, se presenta al objeto moral en referencia al orden de la razón o al bien global de la persona humana y, en él, la aprehensión que hace la razón práctica de la “ordenabilidad” de los actos humanos al bien y al fin último que es Dios, la intencionalidad y autorreferencialidad propia de los actos del libre obrar humano, y el concepto personalista y relacional de acto intrínsecamente malo.

Recovering Nussbaum's aristotelian roots

Abstract: The paper examines the relationship between Creating Capabilities and political liberalism. Originally founded on the basis of Aristotelian philosophy, the theory of ‘capabilities’ developed by Nussbaum turns to political liberalism in the mid 90’s. Throughout the article, the principles of both perspectives are depicted and contrasted, focusing on the capacity of affiliation, the concept of common good and the idea of freedom. Severine Deneulin argues that the current reality calls for the capabilities approach to be more rooted in a relational anthropology which the Aristotelian ethical tradition is more akin to. This line can be found in Nussbaum’s first approach to the theory of capabilities, where affiliation as an architectonic capability leads to the common good being the end of political action, and practical reason as an architectonic capability leads to reasoning ordered towards the achievement of the common good, to the detriment of individualism.

Perspectivas y otredad del continente africano en libros de viaje hispánicos (siglos XIV y XVI) y en Javier Reverte

Número monográfico: El viaje y sus discursos

El judaísmo frente al problema bioético del aborto : la vigencia del postulado frente a todo derecho

Resumen: El judaísmo, desde sus cánones y a través del análisis del conceptus, contribuye no solo a lidiar con la forma en la cual en el presente se intenta dirimir la problemática bioética del aborto, sino también a desarrollar un campo de acción y pensamiento aportando consideraciones, juicios y nociones diferentes que permiten mejorar la calidad de discusión y a su vez construir una sociedad más justa y por ende más libre.

Stratification by solid particle suspensions

Turbulence was generated by an oscillating grid above a bed of sediment of spherical glass beads. As expected, part of the sediment was lifted up by the grid action and a suspension layer of depth D formed above the grid. This depth was found remaining independent of grid action but varying with the sediment layer depth when the grid action was kept constant. Volume concentration measurements show the existence of only weak concentration gradients over the layer depth with a rapid fall off in concentration at the outer edge. The theoretical analysis based on a concentration flux model is in good qualitative agreement with observations.

Teoria e prática da atuação das frentes parlamentares : o caso da Frente Parlamentar Mista de Educação em 2011

Descreve o papel e a atuação da Frente Parlamentar Mista de Educação na 54º Legislatura, em 2011. As metas propostas pela Frente e os resultados efetivamente alcançados são examinados à luz das conexões eleitorais que orientam as ações parlamentares, da teoria da escolha racional, da lógica da ação coletiva e da teoria da visibilidade. A preocupação central do estudo é verificar a que serve e a quem serve a criação, ainda que não institucionalizadas, de estruturas corporativas no âmbito do Congresso Nacional, especialmente, no presente caso, de uma Frente Parlamentar que atua de forma discreta, porém vigorosa.

Nota sobre el cine “de romanos” en el siglo XXI

[ES] A la vista del sorprendente éxito de Gladiator (Ridley Scott, 2000) y del aparente revival del cine “de romanos” en el siglo XXI, puede tener su interés una reflexión sobre este fenómeno cultural y social. Ese es el objetivo de este texto, que analiza las diferentes películas rodadas en la última década y los debates surgidos en torno a la relación entre historia y ficción. En el texto se tratan igualmente los cambios sociológicos y culturales sufridos por las sociedades occidentales, muy diferentes de las de la edad dorada del peplum en el siglo XX, por ejemplo en torno al papel de la mujer o la opinión sobre la guerra, y que afectan a los esquemas tradicionales de este peculiar género cinematrográfico.