874 resultados para Período pós-prandial
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Abstract In the current historiographical production there is a manifest interest for the history of female religiosity. The mystic phenomenon, the everyday life and the temporal dimension of the communities, in terms of familiar and social connection to the outside of cloistered spaces, manifestations of creativity and culture, are increasingly treated issues. This interest is also expressed about the Cistercian Order in Portugal. In the female branch, the monastery of St. Benedict of Cástris, officially Cistercian for more than 700 years, has been the target of an interdisciplinary approach that intents to appreciate the impact of the reflections of the Council of Trent in the musical praxis of the nuns. This community, subject to Alcobaça and controlled through Visitors, registers in its documentation not only the presence of nuns that sang and played various instruments, arising mainly from Évora region, a city with a recognized musical tradition, but also registers various expenses related with the musical practice of the monastery. Resumo Regista-se, na actual produção historiográfica, um interesse manifesto pela história da religiosidade feminina. O fenómeno místico, o viver quotidiano e a dimensão temporal das comunidades, em termos de ligação familiar e social ao exterior dos espaços-clausura, as manifestações de criatividade e cultura, são questões cada vez mais tratadas. Esse interesse manifesta-se também para a Ordem de Cister em Portugal, sendo que, no ramo feminino, o mosteiro de S. Bento de Cástris, oficialmente cisterciense há mais de 700 anos, vem sendo alvo de uma abordagem multidisciplinar que procura apreciar os reflexos do Concílio de Trento na praxis musical das religiosas. Esta comunidade, sujeita a Alcobaça e por ela controlada através dos Visitadores, regista na sua documentação não só a presença de religiosas cantoras e tangedoras de vários instrumentos, oriundas maioritariamente da região de Évora, cidade com uma tradição musical reconhecida, como diversas despesas relacionadas com a prática musical do mosteiro.
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Resumo: Apesar da existência de anteriores estudos, tanto em termos nacionais como regionais, e que demonstram a forte presença de escravos em Évora nos séculos XV e XVI, localizar a população escrava na documentação de instituições religiosas femininas da cidade e entender a sua condição de vida nessas comunidades não se revela fácil. Muitas das referências à sua existência são indiretas, ao fazerem parte de um dote ou doação (constando como bens a que se atribui um determinado valor), que podia ser testamentária, de partilhas e sentenças. São também de difícil perceção as tarefas desempenhadas no quotidiano de espaços claustrais, especialmente os femininos, sujeitos às exigências pós-tridentinas. Só com a apresentação de alguns casos, a juntar aos já conhecidos, poderemos sugerir algumas considerações sobre esta matéria. Abstract: Despite the existence of previous studies, both national and regional, studies that demonstrate a strong presence of slaves in Évora in the 15th and 16th centuries, locating them in documents from the city’s female religious communities and understanding their living conditions in those communities is not an easy task. Many of the references to their existence are indirect and related to a dowry or donation (being mentioned as assets with an assigned value), which could be associated with a will, a partition or a sentence. It is also difficult to ascertain the tasks they performed in the everyday life of cloistered communities, particularly the female ones, subject to the post-Tridentine requirements. Only by presenting a series of cases, other than the ones that are already known, will we be able to suggest considerations on this matter.
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A macieira se torna endodormente durante o outono/inverno em resposta a estímulos ambientais, requerendo um somatório de frio para superar este estado. O controle deste processo está intimamente associado ao genótipo e as condições de cultivo. Já existem resultados isolados da variação de alguns hormônios, mas não consideram a inter-relação e o balanço destes compostos ao longo do período hibernal. O objetivo deste trabalho foi desenvolver um protocolo para uma análise simultânea de diferentes hormônios (ácido abscísico, auxina, giberelina, zeatina, ácido salicílico e jasmonato) em gemas, visando caracterizar o balanço destes compostos durante o processo de endodormência.
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O objetivo é avaliar a produtividade e qualidade alimentar de milheto e sorgo em iLP, com plantio direto ou convencional em terra firme e seu impacto na matéria orgânica do solo. Parcelas de 5 m x 5 m de ADR 300 e ADR 500 (milheto) e BRS 802 e BRS 810 (sorgo), arranjadas em fatorial, seguindo delineamento inteiramente casualizado com quatro repetições, serão semeadas em plantio direto e convencional em área antes cultivada com milho.
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Almejando aclarar a nebulosa realidade empírica vivida no período da globalização, objetivamos, a partir da região do Seridó (Brasil), entender dialeticamente como o período da globalização está presente nesta região, bem como entender a região e sua funcionalização frente às modernidades trazidas pelo período. Visando alcançar os objetivos, utilizamos como estratégia metodológica, confrontar variadas referências que tratam do período da globalização com os dados empíricos oriundos da região do Seridó. Além de buscar informações diretamente no campo, optamos também por realizar pesquisas em outras fontes bibliográficas e banco de dados que tratam especificamente da realidade regional. O estudo empírico da região do Seridó propiciou elencar algumas contribuições geográficas de como melhor entender o período atual e suas manifestações em “regiões letárgicas”, em que temos como realidade territorial, “velhas” formas-conteúdos convivendo com as novas, graças à vasta gama de possibilidades produtivas e, sobretudo, da circulação de insumos, produtos e dinheiro, de idéias e informações, das ordens e dos homens. Com a nova reorganização dada pelo período atual, regiões letárgicas como o Seridó, mesmo que não estejam na rota prioritária de investimentos produtivos das grandes firmas globais, inserem-se no período, mesmo que marginalmente, sobretudo via vários tipos de consumo.
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A produção brasileira de maçãs está inserida em 34.664 hectares na safra de 2016, sendo 17.028 hectares plantados em Santa Catarina, 15.716 hectares no Rio Grande do Sul e 1.490 hectares no Paraná (IBGE, 2016). A cultivar de maçã Pink Lady® foi obtida do cruzamento entre Golden Delicious e Lady Williams, buscando-se da cultivar Golden Delicious a boa qualidade organoléptica e a baixa ocorrência de escaldadura e da cultivar Lady Williams a boa firmeza de polpa, o bom potencial de armazenamento e a baixa suscetibilidade ao?bitter pit? (KELLERHALS; RAPILLARD, 2002). A utilização de etefom visa melhorar a coloração dos frutos bem como antecipar a colheita, apresentando efeitos benéficos sobre a qualidade do fruto, acidez titulável, teor de sólidos solúveis e firmeza da polpa (SEIBERT et al., 2000). Entretanto, o etefom acelera o processo de amadurecimento dos frutos, podendo reduzir o período de conservação da maçã (FAN et al., 1998). Em função disso, torna-se importante avaliar os efeitos da aplicação de etefom em pré-colheita e suas implicações em pós-colheita. O objetivo desse trabalho foi avaliar o uso de etefom em pré-colheita em frutos de ?PinkLady® ? e verificar as suas implicações na pós-colheita dos frutos na região de Vacaria/RS no ciclo produtivo de 2015/2016.
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As narrativas e as histórias sobre as experiências dos professores em formação, antes e durante seu trabalho profissional, são comumente utilizadas para entender as identidades dos professores de línguas, por elas estar influenciadas pelas experiências gravadas nas memórias. Porém, o conceito de pós-memória emergiu recentemente e parece não ter sido ainda utilizado na educação dos professores de línguas. Neste artigo, se comentam as possibilidades de utilizar o conceito de pós-memória na educação de professores de línguas, através das narrativas sobre as suas experiências. O propósito é estudar com mais profundidade as influências de eventos históricos traumáticos, como O Regime Militar no Brasil, sobre as identidades dos professores de inglês no Brasil, antes e durante seu trabalho profissional, através das narrativas e histórias sobre as suas experiências. O principal objetivo é analisar as relações e inter-relações entre memória, pós-memória e experiências e as identidades dos professores de inglês, especialmente com relação às experiências influenciadas pelo período militar no Brasil.
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Recombinant glucagon-like peptide-1 (7–36)amide (rGLP-1) was recently shown to cause significant weight loss in type 2 diabetics when administered for 6 weeks as a continuous subcutaneous infusion. The mechanisms responsible for the weight loss are not clarified. In the present study, rGLP-1 was given for 5d by prandial subcutaneous injections (PSI) (76nmol 30min before meals, four times daily; a total of 302·4nmol/24h) or by continuous subcutaneous infusion (CSI) (12·7nmol/h; a total of 304·8nmol/24h). This was performed in nineteen healthy obese subjects (mean age 44·2 (sem 2·5) years; BMI 39·0 (sem 1·2)kg/m2) in a prospective randomised, double-blind, placebo-controlled, cross-over study. Compared with the placebo, rGLP-1 administered as PSI and by CSI generated a 15% reduction in mean food intake per meal (P=0·02) after 5d treatment. A weight loss of 0·55 (sem 0·2) kg (P<0·05) was registered after 5d with PSI of rGLP-1. Gastric emptying rate was reduced during both PSI (P<0·001) and CSI (P<0·05) treatment, but more rapidly and to a greater extent with PSI of rGLP-1. To conclude, a 5d treatment of rGLP-1 at high doses by PSI, but not CSI, promptly slowed gastric emptying as a probable mechanism of action of increased satiety, decreased hunger and, hence, reduced food intake with an ensuing weight loss.
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The present study investigated metabolic responses to fat and carbohydrate ingestion in lean male individuals consuming an habitual diet high or low in fat. Twelve high-fat phenotypes (HF) and twelve low-fat phenotypes (LF) participated in the study. Energy intake and macronutrient intake variables were assessed using a food frequency questionnaire. Resting (RMR) and postprandial metabolic rate and substrate oxidation (respiratory quotient; RQ) were measured by indirect calorimetry. HF had a significantly higher RMR and higher resting heart rate than LF. These variables remained higher in HF following the macronutrient challenge. In all subjects the carbohydrate load increased metabolic rate and heart rate significantly more than the fat load. Fat oxidation (indicated by a low RQ) was significantly higher in HF than in LF following the fat load; the ability to oxidise a high carbohydrate load did not differ between the groups. Lean male subjects consuming a diet high in fat were associated with increased energy expenditure at rest and a relatively higher fat oxidation in response to a high fat load; these observations may be partly responsible for maintaining energy balance on a high-fat (high-energy) diet. In contrast, a low consumer of fat is associated with relatively lower energy expenditure at rest and lower fat oxidation, which has implications for weight gain if high-fat foods or meals are periodically introduced to the diet.
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Monetary valuations of the economic cost of health care–associated infections (HAIs) are important for decision making and should be estimated accurately. Erroneously high estimates of costs, designed to jolt decision makers into action, may do more harm than good in the struggle to attract funding for infection control. Expectations among policy makers might be raised, and then they are disappointed when the reduction in the number of HAIs does not yield the anticipated cost saving. For this article, we critically review the field and discuss 3 questions. Why measure the cost of an HAI? What outcome should be used to measure the cost of an HAI? What is the best method for making this measurement? The aim is to encourage researchers to collect and then disseminate information that accurately guides decisions about the economic value of expanding or changing current infection control activities.
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INTRODUCTION: Performance status (PS) 2 patients with non-small cell lung cancer (NSCLC) experience more toxicity, lower response rates, and shorter survival times than healthier patients treated with standard chemotherapy. Paclitaxel poliglumex (PPX), a macromolecule drug conjugate of paclitaxel and polyglutamic acid, reduces systemic exposure to peak concentrations of free paclitaxel and may lead to increased concentrations in tumors due to enhanced vascular permeability. METHODS: Chemotherapy-naive PS 2 patients with advanced NSCLC were randomized to receive carboplatin (area under the curve = 6) and either PPX (210 mg/m/10 min without routine steroid premedication) or paclitaxel (225 mg/m/3 h with standard premedication) every 3 weeks. The primary end point was overall survival. RESULTS: A total of 400 patients were enrolled. Alopecia, arthralgias/myalgias, and cardiac events were significantly less frequent with PPX/carboplatin, whereas grade ≥3 neutropenia and grade 3 neuropathy showed a trend of worsening. There was no significant difference in the incidence of hypersensitivity reactions despite the absence of routine premedication in the PPX arm. Overall survival was similar between treatment arms (hazard ratio, 0.97; log rank p = 0.769). Median and 1-year survival rates were 7.9 months and 31%, for PPX versus 8 months and 31% for paclitaxel. Disease control rates were 64% and 69% for PPX and paclitaxel, respectively. Time to progression was similar: 3.9 months for PPX/carboplatin versus 4.6 months for paclitaxel/carboplatin (p = 0.210). CONCLUSION: PPX/carboplatin failed to provide superior survival compared with paclitaxel/carboplatin in the first-line treatment of PS 2 patients with NSCLC, but the results with respect to progression-free survival and overall survival were comparable and the PPX regimen was more convenient. © 2008International Association for the Study of Lung Cancer.
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DNA adopts different conformations not only based on novel base pairs, but also with different chain polarities. Besides several duplex structures (A, B, Z, parallel stranded (ps)-DNA, etc.), DNA also forms higher-order structures like triplex, tetraplex, and i-motif. Each of these structures has its own biological significance. The ps-duplexes have been found to be resistant to certain nucleases and endonucleases. Molecules that promote triple-helix formation have significant potential. These investigations have many therapeutic advantages which may be useful in the regulation of the expression of genes responsible for certain diseases by locking either their transcription (antigene) or translation (antisense). Each DNA minor groove binding ligand (MGBL) interacts with DNA through helical minor groove recognition in a sequence-specific manner, and this interferes with several DNA-associated processes. Incidentally, these ligands interact with some non-B-DNA and with higher-order DNA structures including ps-DNA and triplexes. While the design and recognition of minor grooves of duplex DNA by specific MGBLs have been a topic of many reports, limited information is available on the binding behavior of MGBLs with nonduplex DNA. In this review, we summarize various attempts of the interaction of MGBLs with ps-DNA and DNA triplexes.
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Cd(0.75)PS(3)A(0.5)(H2O)(y) [A = Na, K and Cs], synthesized by the ion-exchange intercalation reaction of the insulating layered CdPS3, exhibits interesting electrical properties. The electrical properties are strongly dependent on the extent of hydration of the alkali ion which resides in the interlamellar space. In the potassium and caesium ion-exchanged compounds, y = I, the lattice expansion is similar to 3 Angstrom and the electric response characteristic of a dielectric. In the as prepared A = Na compound, y = 2, the lattice expansion is 5.6 Angstrom, the compound is conducting with a DC conductance of 3 x 10(-5) S cm(-1) at 300 K. Cd0.75PS3Na0.5(H2O)(y), y = 2, on evacuation or on heating looses water, reversibly, to form a y = 1 phase with electrical properties similar to that of the K and Cs ion exchange intercalation compounds.
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An all-digital on-chip clock skew measurement system via subsampling is presented. The clock nodes are sub-sampled with a near-frequency asynchronous sampling clock to result in beat signals which are themselves skewed in the same proportion but on a larger time scale. The beat signals are then suitably masked to extract only the skews of the rising edges of the clock signals. We propose a histogram of the arithmetic difference of the beat signals which decouples the relationship of clock jitter to the minimum measurable skew, and allows skews arbitrarily close to zero to be measured with a precision limited largely by measurement time, unlike the conventional XOR based histogram approach. We also analytically show that the proposed approach leads to an unbiased estimate of skew. The measured results from a 65 nm delay measurement front-end indicate that for an input skew range of +/- 1 fan-out-of-4 (FO4) delay, +/- 3 sigma resolution of 0.84 ps can be obtained with an integral error of 0.65 ps. We also experimentally demonstrate that a frequency modulation on a sampling clock maintains precision, indicating the robustness of the technique to jitter. We also show how FM modulation helps in restoring precision in case of rationally related clocks.