Toxemia da prenhez relacionada à gestação múltipla patológica em ovelha

The pregnancy toxaemia affects pregnant females in the final third of pregnancy and, in most cases, with multiple fetuses characterizing its relationship with pathology of multiple pregnancy, because, in this situation, the energy demand of the female is very large. The pregnancy toxaemia develops from a negative energy balance and the consequent mobilization of lipids. Fatty acids produced are directed to the liver to be oxidized via acid cycle to produce energy and causing the ketosis. This paper describes the case of a sheep treated at the Veterinary Hospital of Paranaense University - UNIPAR, Campus II - Umuarama/PR with multiple pregnancy of four lambs and consequent pregnancy toxaemia.

Desempenho operacional de semeadora e produtividade do milho em plantio direto e cultivo mínimo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Zonas Estratégicas e Estruturais para os Trânsitos Ilícitos (ZEETI): desafios à zona de paz na América do Sul

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da hipertensão arterial no padrão fenotípico da lesão periapical, na diferenciação dos osteoclastos, na resposta teciduale na capacidade de mineralização do cimento reparador MTA

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Grupo de apoiadores e cooperlix em Presidente Prudente-SP, Brasil: modelo e evolução de suas relações durante quinze anos

Pós-graduação em Geografia - FCT

Ações educativas sobre prevenção de acidentes infantis com professoras de educação infantil

Pós-graduação em Educação - FFC

Análise do processo de formação como mediadora entre o público e a arte

The proposed work is located in education field in exhibition spaces of art and seeks to analyze a process of formation as a mediator focusing on the public's relationship with art, taking into account the fact that often the general public does not dominate the codes of this area, being incumbent upon mediator introduce them. One of the main points to be analyzed is the impact that can be generated by the contact of the visitor with the mediator in the exhibition space, considering a spectrum of possibilities, where at one end focuses the belonging and in the other the symbolic violence. In this direction this research aims to build a relationship of emancipation and autonomy of both, the educator and the visitor. It is known that the concept of public is a generalization, therefore, the analysis of the mediation process, are having as support the experiences lived by the mediator, especially, in the relationship with the lay public. The locations of the experiences lived, were the SESC Pompéia and the Pavilion of the Bienal of São Paulo, different places, but both with the potential to generate reception and / or distances, shot through space (architecture), bodies, codes, accesses, works of art, repertoires, expographic and especially through the mobilization of educator front of all these issues. The cutting of the research covers the experience of the educator (as an intern and professional) in six exhibitions, in these two spaces, between the years 2010 to 2015.

A construção social do mercado colaborativo de software livre durante o Governo Lula: agentes, estratégias e discursos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise do processo de formação como mediadora entre o público e a arte

The proposed work is located in education field in exhibition spaces of art and seeks to analyze a process of formation as a mediator focusing on the public's relationship with art, taking into account the fact that often the general public does not dominate the codes of this area, being incumbent upon mediator introduce them. One of the main points to be analyzed is the impact that can be generated by the contact of the visitor with the mediator in the exhibition space, considering a spectrum of possibilities, where at one end focuses the belonging and in the other the symbolic violence. In this direction this research aims to build a relationship of emancipation and autonomy of both, the educator and the visitor. It is known that the concept of public is a generalization, therefore, the analysis of the mediation process, are having as support the experiences lived by the mediator, especially, in the relationship with the lay public. The locations of the experiences lived, were the SESC Pompéia and the Pavilion of the Bienal of São Paulo, different places, but both with the potential to generate reception and / or distances, shot through space (architecture), bodies, codes, accesses, works of art, repertoires, expographic and especially through the mobilization of educator front of all these issues. The cutting of the research covers the experience of the educator (as an intern and professional) in six exhibitions, in these two spaces, between the years 2010 to 2015.

A construção social do mercado colaborativo de software livre durante o Governo Lula: agentes, estratégias e discursos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Formulação de Estratégias no Turismo: um estudo em órgãos municipais do Estado de São Paulo

O objetivo desta pesquisa é investigar a formulação de estratégias em órgãos públicos municipais de turismo do Estado de São Paulo. Para este fim realizou-se um estudo de casos múltiplos em seis municípios: Santos, Guarujá, Praia Grande, São Caetano do Sul, Rio Grande da Serra e Guarulhos. Os dados foram coletados através de entrevistas semiestruturadas. Constatou-se que estes órgãos municipais desenvolvem um encaminhamento lógico na formulação de estratégias, os quais apresentam em seus estágios iniciais características de informalidade, e na evolução deste processo contemplam-se necessidades e desejos dos consumidores e de outros stakeholders. Todo o processo de formulação de estratégias recebe influência de diversos stakeholders. As principais dificuldades encontradas no processo de formulação estratégica foram: falta de mobilização coletiva, conflitos de interesses e carência de recursos.

Complete Sequence of Broad-Host-Range Plasmid pRIO-5 Harboring the Extended-Spectrum-beta-Lactamase Gene bla(BES-1)

Broad-host-range plasmid pRIO-5, harboring the extended-spectrum beta-lactamase bla(BES-1) gene in Serratia marcescens, was fully sequenced. Analysis of the 12,957-bp sequence of this IncP6-type plasmid revealed that the bla(BES-1) gene was associated with two copies of the insertion sequence IS26. The promoter responsible for the bla(BES-1) expression was hybrid, made of a - 35 box located inside the inverted repeat of IS26 and a - 10 box inside a remnant of an insertion sequence.

In vivo hydroquinone exposure impairs MCP-1 secretion and monocyte recruitment into the inflamed lung

Alveolar macrophages (AMs) are important cells in the resolution of the inflammatory process and they come into direct contact with inhaled pollutants. Hydroquinone (HQ) is an environmental pollutant and a component of cigarette smoke that causes immunosuppressive effects. In the present work, we showed that mice exposed to low levels of aerosolized HQ (25 ppm; 1 h/day/5 days) presented impaired mononuclear cell migration to the lipopolysaccharide (LPS)-inflamed lung. This may have been due to reduced monocyte chemoattractant protein-1 (MCP-1) secretion into bronchoalveolar lavage fluid (BALF), and it was not related to alterations to mononuclear cell mobilization into the blood or adhesion molecules expression on mononuclear cell membranes. Corroborating the actions of HQ on MCP-1 secretion, reduced MCP-1 concentrations were also found in the supernatant of ex vivo AM and tracheal tissue collected from HQ-exposed mice. A direct action of HQ on MCP-1 secretion, resulting from impaired gene synthesis, was verified by in vitro incubation of naive AMs or tracheal tissue with HQ. The role of reduced levels of MCP-1 in the BALF on monocyte migration was analysed in the human monocytic lineage THP-1 in in vitro chemotaxis assays, which showed that the reduced concentrations of MCP-1 found in the BALF or cell supernatants from HQ-exposed mice impaired cell migration. Considering the fact that MCP-1 presents a broad spectrum of actions on pathophysiological conditions and that resident mononuclear cells are involved in lung tissue homeostasis and in immune host defence, the mechanism of HQ toxicity presented herein might be relevant to the genesis of infectious lung diseases in smokers and in inhabitants of polluted areas. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

Matrix Support in Mental Health: Achievements and Limits in Primary Health Care

Changes in mental health care in the city of Fortaleza (Northeastern Brazil) have a recent historical and political process. Compared to other municipalities of the State of Ceara, which in the early 1990s were already pioneers in the process, Fortaleza has not implemented the changes due to the interests of psychiatric hospitals, of psychiatric outpatient clinics of the public network, and because of the difficulty in managing the new mental health devices and equipment present in Primary Care. In the municipality, the reorganization of mental health actions and services has required that the Primary Care Network faces the challenge of assisting mental health problems with the implementation of Matrix Support. In light of this context, we aimed to evaluate Matrix Support in mental health in Primary Care Units and to identify achievements and limitations in the Primary Care Units with Matrix Support. This study used a qualitative approach and was carried out by means of a case study. We interviewed twelve professionals from the Family Health Teams of four Units with implemented Matrix Support. The analysis of the information reveals that access, decision making, participation and the challenges of implementing Matrix Support are elements that are, in a dialectic way, weak and strong in the reorganization of services and practices. The presence of Matrix Support in Primary Care highlights the proposal of dealing with mental health within the network in the municipality. The process has not ended. Mobilization, awareness-raising and qualification of Primary Care have to be enhanced constantly, but implementation has enabled, to the service and professionals, greater acceptance of mental health in Primary Care.

Pontomedullary and hypothalamic distribution of Fos-like immunoreactive neurons after acute exercise in rats

During exercise, intense brain activity orchestrates an increase in muscle tension. Additionally, there is an increase in cardiac output and ventilation to compensate the increased metabolic demand of muscle activity and to facilitate the removal of CO2 from and the delivery of O-2 to tissues. Here we tested the hypothesis that a subset of pontomedullary and hypothalamic neurons could be activated during dynamic acute exercise. Male Wistar rats (250-350 g) were divided into an exercise group (n = 12) that ran on a treadmill and a no-exercise group (n = 7). Immunohistochemistry of pontomedullary and hypothalamic sections to identify activation (c-Fos expression) of cardiorespiratory areas showed that the no-exercise rats exhibited minimal Fos expression. In contrast, there was intense activation of the nucleus of the solitary tract, the ventrolateral medulla (including the presumed central chemoreceptor neurons in the retrotrapezoid/parafacial region), the lateral parabrachial nucleus, the Kolliker-Fuse region, the perifornical region, which includes the perifornical area and the lateral hypothalamus, the dorsal medial hypothalamus, and the paraventricular nucleus of the hypothalamus after running exercise. Additionally, we observed Fos immunoreactivity in catecholaminergic neurons within the ventrolateral medulla (C1 region) without Fos expression in the A2, A5 and A7 neurons. In summary, we show for the first time that after acute exercise there is an intense activation of brain areas crucial for cardiorespiratory control. Possible involvement of the central command mechanism should be considered. Our results suggest whole brain-specific mobilization to correct and compensate the homeostatic changes produced by acute exercise. (c) 2012 IBRO. Published by Elsevier Ltd. All rights reserved.