Complete Sequence of Broad-Host-Range Plasmid pRIO-5 Harboring the Extended-Spectrum-beta-Lactamase Gene bla(BES-1)


Autoria(s): Bonnin, Remy A.; Poirel, Laurent; Mello Sampaio, Jorge Luiz; Nordmann, Patrice
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

14/10/2013

14/10/2013

2012

Resumo

Broad-host-range plasmid pRIO-5, harboring the extended-spectrum beta-lactamase bla(BES-1) gene in Serratia marcescens, was fully sequenced. Analysis of the 12,957-bp sequence of this IncP6-type plasmid revealed that the bla(BES-1) gene was associated with two copies of the insertion sequence IS26. The promoter responsible for the bla(BES-1) expression was hybrid, made of a - 35 box located inside the inverted repeat of IS26 and a - 10 box inside a remnant of an insertion sequence.

INSERM

INSERM [U914]

Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]

Ministere de lEducation Nationale et de la Recherche

Universite Paris XI, France

Universite Paris XI, France

European Community , TEMPOtestQC ]

European Community [TROCAR [HEALTH-F3-2008-223031], TEMPOtest-QC [HEALTH-2009-241742]]

Identificador

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, WASHINGTON, v. 56, n. 2, supl. 1, Part 1, pp. 1116-1119, FEB, 2012

0066-4804

http://www.producao.usp.br/handle/BDPI/34504

10.1128/AAC.00480-11

http://dx.doi.org/10.1128/AAC.00480-11

Idioma(s)

eng

Publicador

AMER SOC MICROBIOLOGY

WASHINGTON

Relação

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Direitos

closedAccess

Copyright AMER SOC MICROBIOLOGY

Palavras-Chave #SERRATIA-MARCESCENS #REGION #MOBILIZATION #PRA2 #MICROBIOLOGY #PHARMACOLOGY & PHARMACY
Tipo

article

original article

publishedVersion