The Beacon, February 2, 2011

Vol. 22, Issue 9, 8 pages

Theorizing suburban public space in Kendall

The purpose of this study was to determine whether public space in the suburbs has the same settings as that of a central city or if it has its own characteristics. In order to approach this problem the area of Kendall was thoroughly studied by examining aerial maps, historic images and writings of local historians such as Donna Knowles Born. Heavy emphasis was placed on the transformation of the original one-mile grid characteristic of the city of Miami. As the area of Kendall was being developed, the grid was transformed into an irregular and organic method of laying out a street system that directly affected pedestrian life. It became evident, therefore, that Kendall is primarily geared toward automobile movement, thus affecting the setting of public space. This also restricted social events forcing them to concentrate in specific places like the malls. These findings demonstrated that malls are centers of social interaction concentrating many social activities in one place. In other words, a mall serves as a common meeting place in the otherwise vast spread of the suburbs. This thesis also explains how public spaces in a suburban context can affect the community by working as filtering agents between the immediate context of a particular site and the overall city. The project, a "Wellness Center and Park" for the Kendall area, was an exploration of these filtering agents and the transitions they engendered. The research upon which this project was based recognized the important role of the site's history as well as extrapolating as to its future potential.

DISCURSO DA MARCA: uma abordagem da semiose comunicacional da marca

A tese aborda a constituição do significado da marca sob a perspectiva de seu discurso na sociedade de consumo. Por meio dos objetivos propostos, (a) a descrição do processo comunicacional da marca como um discurso social; (b) a demonstração da constituição do significado da marca pela circulação de efeitos de sentido; e (c) a articulação da teoria social que fundamenta o processo, intenta-se explorá-la como possibilidade teórica explicativa por meio do discursivo na semiose social. A tese justifica-se pelo desenvolvimento de uma abordagem comunicacional para a constituição do significado da marca (relevância teoria) e pela possibilidade de interferência na realidade social a partir do conhecimento de como a marca institui-se como um discurso social (relevância social). Trata-se de um trabalho teórico, de natureza qualitativa, a partir de uma pesquisa exploratória, com vistas a propor a construção de uma semiose da marca. Concluiu-se que é teoricamente pertinente a constituição do significado da marca contemporânea fundamentalmente por um processo de produção de sentido social na sociedade de consumo.

Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans.

BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is a globally prevalent cause of diarrhea. Though usually self-limited, it can be severe and debilitating. Little is known about the host transcriptional response to infection. We report the first gene expression analysis of the human host response to experimental challenge with ETEC. METHODS: We challenged 30 healthy adults with an unattenuated ETEC strain, and collected serial blood samples shortly after inoculation and daily for 8 days. We performed gene expression analysis on whole peripheral blood RNA samples from subjects in whom severe symptoms developed (n = 6) and a subset of those who remained asymptomatic (n = 6) despite shedding. RESULTS: Compared with baseline, symptomatic subjects demonstrated significantly different expression of 406 genes highlighting increased immune response and decreased protein synthesis. Compared with asymptomatic subjects, symptomatic subjects differentially expressed 254 genes primarily associated with immune response. This comparison also revealed 29 genes differentially expressed between groups at baseline, suggesting innate resilience to infection. Drug repositioning analysis identified several drug classes with potential utility in augmenting immune response or mitigating symptoms. CONCLUSIONS: There are statistically significant and biologically plausible differences in host gene expression induced by ETEC infection. Differential baseline expression of some genes may indicate resilience to infection.

In hoc opere continentur totius phylosophie naturalis paraphrases hoc ordine digeste : Octo physicorum Aristotelis paraphrasis, Quatuor de celo et mundo completorum paraphrasis, ... Introductio metaphysica, Dialogi quattuor ad Metaphysicoru[m] intelligent

Sign: a-z8, [et]8, A-T8, U4

Development of a knowledge sharing framework for improving the testing processes in global product development

As identified by Griffin (1997) and Kahn (2012), manufacturing organisations typically improve their market position by accelerating their product development (PD) cycles. One method for achieving this is to reduce the time taken to design, test and validate new products, so that they can reach the end customer before competition. This paper adds to existing research on PD testing procedures by reporting on an exploratory investigation carried out in a UK-based manufacturing plant. We explore the organisational and managerial factors that contribute to the time spent on testing of new products during development. The investigation consisted of three sections, viz. observations and process modelling, utilisation metrics and a questionnaire-based investigation, from which a proposed framework to improve and reduce the PD time cycle is presented. This research focuses specifically on the improvement of the utilisation of product testing facilities and the links to its main internal stakeholders - PD engineers.

Reputation performance: a portfolio selection approach

This paper introduces a normative view on corporate reputation strategic management. Reputation performance is conceptualised as the outcome of complex processes and social interactions and the lack of a holistic reputation performance management framework is identified. In an attempt to fill this gap, a portfolio-based approach is put forward. Drawing on the foundations of modern portfolio theory we create a portfolio-based reputation management algorithmic model where reputation components and priorities are weighted by decision makers and shape organisational change in an attempt to formulate a corporate reputation strategy. The rationale of this paper is based on the foundational consideration of organisations as choosing he optimal strategy by seeking to maximise their reputation performance while maintaining organisational stability and minimising organisational risk.

Reputation Performance: a portfolio selection approach

This paper introduces a normative view on corporate reputation management; an algorithmic model for reputation-driven strategic decision making is proposed and corporate reputation is conceptualized as influenced by a selection among organizational priorities. A portfolio-based approach is put forward; we draw on the foundations of portfolio theory and we create a portfolio-based reputation management model where reputation components and priorities are weighted by decision makers and shape organizational change in an attempt to formulate a corporate reputation strategy. The rationale of this paper is based on the foundational consideration of organizations as choosing the optimal strategy by seeking to maximize performance on corporate reputation capital while maintaining organizational stability and minimizing organizational risk.

A process-based Knowledge Management framework supported by ARIS Enterprise Modelling architecture

Knowledge and its management have been respectively accepted as a critical resource and a core business competency. Despite that literature proves the existence of a gap between the theoretical considerations of Knowledge Management (KM) and their efficient application. Such lacking, we argue, derives from the missing link between a framework of Knowledge Management and the particular methods and guidelines of its implementation. In an attempt to bridge this gap, an original, process- based holistic Knowledge Management framework is proposed, aiming to address the problem of knowledge management application and performance by utilising a set of well accepted Enterprise Modelling (EM) methods and tools.

La fijación léxica en el "Corpus diacrónico del español del Reino de Granada (CORDEREGRA)"

El estudio de las combinaciones léxicas según su grado de fijación y su distinción en combinaciones libres, colocaciones y locuciones ha sido realizado desde la perspectiva sincrónica. Planteamos la posibilidad de aplicar las pautas para distinguir estos tipos de estructuras en materiales de tipo diacrónico. Concretamente, nos basamos en los documentos que componen el Corpus del Español del Reino de Granada (CORDEREGRA) para valorar los materiales de este corpus histórico-lingüístico y comprobar si los criterios sincrónicos se pueden aplicar al estudio de documentos de otros siglos.

Francesco Grimaldi, un mercader-banquero genovés entre Granada, la corte e Inglaterra (siglos xv-xvi)

Los estudios sobre la comunidad genovesa del Reino de Granada suelen centrarse en las actividades desarrolladas en el territorio y rara vez en la reconstrucción de trayectorias individuales, circunstancia determinada por el recurso casi exclusivo a los protocolos notariales. El caso de Francesco Grimaldi es singular por muchas razones: su localización en fuentes de naturaleza muy variada –protocolos notariales de Granada y Málaga, Registro del Sello de Simancas y Granada, Chancillería de Valladolid, el epistolario del comendador Fuensalida y el archivo privado de la familia Grimaldo de Cáceres– ha permitido seguir su presencia y sus actividades en Granada, la Corte e Inglaterra –donde desempeñó un papel fundamental en el matrimonio entre Catalina de Aragón y Enrique VIII–. Así se conoce su interés por los préstamos y el negocio de la renta, las circunstancias de su matrimonio con Francisca de Cáceres y la adquisición de un importante patrimonio en el reino granadino.

El patrocinio artístico femenino a través de la monarquía hispánicarchivo de ordenador] : Sancha de León, Isabel La Católica e Isabel de Farnesio

[ES]Análisis del patrocinio artístico ejercido por soberanas españolas de los siglos XI al XVIII. Las reinas elegidas son: Sancha de León (m. 1067) y su legitimación del poder a través de las artes y el tesoro de San Isidoro de León; Isabel de Castilla (1451-1504) y la pintura flamenca: su pintor de cámara Juan de Flandes; e Isabel de Farnesio (1692-1766) y la imposición del arte italiano en el siglo XVIII español con sus colecciones de escultura y pintura.