La promozione musicale sui social network

L’industria musicale non ha mai vissuto un periodo di cambiamento così intenso e profondo come al giorno d’oggi. La sua digitalizzazione attraverso lo streaming musicale, la nascita di nuovi dispositivi che ne consentano la fruizione e l’interazione tra industria discografica e un pubblico sempre più centrale e determinante nelle scelte produttive e distributive del mercato, sono solo alcuni degli aspetti, indubbiamente i più importanti, che caratterizzano questa nuova fase della storia della musica. Attraverso questa tesi di laurea ho cercato di osservare e approfondire come in questi ultimi anni l’industria musicale si stia approcciando al mondo dei social network per promuovere e distribuire i prodotti musicali. Viene tracciato un quadro generale dell’ambiente dei social media, mostrandone sia i lati tecnologici che sociali, fino ad evidenziarne aspetti positivi e negativi. Nella seconda parte della trattazione invece, vengono osservate le strategie comunicative adottate dagli artisti e dagli addetti ai lavori per arrivare più efficacemente al pubblico e il ruolo che rivestono i vecchi media e l’utenza nel diffondere su larga scala il prodotto musicale.

L’efficacia della riabilitazione equestre in soggetti con sclerosi multipla sui parametri funzionali del cammino e sulla qualità della vita: Revisione Sistematica della Letteratura

Background. La sclerosi multipla (SM) è una malattia neurodegenerativa che colpisce il sistema nervoso centrale. I sintomi si manifestano prima dei 55 anni di età, possono essere molto diversi tra loro. Al momento non esiste una cura definitiva, ma sono disponibili tecniche riabilitative che modificano il suo andamento, tra cui la riabilitazione equestre, che consiste in attività svolte con l'aiuto del cavallo a fini di cura. Obiettivi. Lo scopo di questo studio è quello di indagare l’efficacia della riabilitazione equestre sui parametri funzionali del cammino e la qualità della vita in persone con SM. Metodi. Le banche dati visionate per questo studio sono state PUBMED, PEDro, Cochrane Central Register of Controlled Trial, Web of Science e Scopus. Nella revisione sono stati inclusi i Randomized Controlled Trial (RCT) che indagavano i parametri funzionali del cammino e la qualità della vita; articoli che esaminavano soggetti con sclerosi multipla senza limiti di età e sesso, in lingua inglese, pubblicati tra il 2010 e il 2020 e di cui era reperibile il full text. Risultati. Gli studi inclusi sono stati quattro RCT. Gli outcome indagati sono stati i parametri funzionali del cammino e la qualità della vita. In ogni studio esaminato si osserva un miglioramento significativo per ogni misura di outcome, in particolare la qualità della vita. Conclusioni. Ogni studio ha evidenziato come la riabilitazione equestre abbia influito positivamente sul decorso della SM. Riguardo i trial clinici esaminati, il numero esiguo dei partecipanti ai singoli studi, la durata eterogenea delle sessioni, l’impossibilità di disporre della descrizione della seduta, l’utilizzo di scale differenti per ogni studio e l’aver considerato parametri diversi per valutare uno stesso outcome non permettono di avere risultati estendibili a tutta la popolazione. Risulta necessario un ulteriore approfondimento in merito per comprendere la reale efficacia della riabilitazione equestre.

Studio osservazionale sui meccanismi modulatori lessicali della forza illocutoria in interpretazione simultanea IT-EN nel Parlamento Europeo

L’obiettivo principale del presente studio osservazionale consiste nell’offrire una prospettiva su alcuni fenomeni linguistici e nell’analizzare le strategie adottate dalle/dagli interpreti innanzi ad esse. I fenomeni linguistici, in italiano, oggetto della nostra analisi sono i seguenti: metacommenti, verbi modalizzatori, avverbi, forme impersonali, aggettivi, il “noi” come pronome personale con funzione inclusiva, soggetto del verbo coniugato alla prima persona plurale e gli aggettivi possessivi che da esso derivano (“nostro”, “nostra”, “nostri”, “nostre”). Questi fenomeni sono da noi analizzati in veste di modulatori della forza illocutoria e, pertanto, comportano una sua mitigazione oppure un rafforzamento. Il Parlamento Europeo è un contesto in cui il dibattito politico si svolge sotto l’osservazione di norme che regolano la modalità degli scambi comunicativi, ma queste non escludono la possibilità che Membri del Parlamento Europeo si servano di modulatori della forza illocutoria che permettano loro di essere più persuasivi o persino giungere ad essere offensivi nei confronti di altri soggetti. In questo studio osservazionale, i fenomeni sopra menzionati sono analizzati nella combinazione linguistica dall’italiano verso l’inglese. Questa combinazione è stata scelta in quanto è la più frequente – nelle sessioni del Parlamento Europeo – con italiano come lingua di partenza dell’interpretazione. Il materiale oggetto dell’analisi è composto da discorsi che sono stati trascritti utilizzando alcune convenzioni del metodo di trascrizione Jefferson, applicato tanto nella versione originale del discorso, in italiano, pronunciata dal Membro del Parlamento Europeo, così come nella versione dell’interprete, in inglese. La dimensioni del corpus è di 121 minuti di discorso trascritto, in italiano e in inglese, per un totale di 242 minuti.

Beam-energy Dependence Of The Directed Flow Of Protons, Antiprotons, And Pions In Au+au Collisions.

Rapidity-odd directed flow (v1) measurements for charged pions, protons, and antiprotons near midrapidity (y=0) are reported in sNN=7.7, 11.5, 19.6, 27, 39, 62.4, and 200 GeV Au+Au collisions as recorded by the STAR detector at the Relativistic Heavy Ion Collider. At intermediate impact parameters, the proton and net-proton slope parameter dv1/dy|y=0 shows a minimum between 11.5 and 19.6 GeV. In addition, the net-proton dv1/dy|y=0 changes sign twice between 7.7 and 39 GeV. The proton and net-proton results qualitatively resemble predictions of a hydrodynamic model with a first-order phase transition from hadronic matter to deconfined matter, and differ from hadronic transport calculations.

What Is The Best Indication For Single-incision Ophira Mini Sling? Insights From A 2-year Follow-up International Multicentric Study.

The Ophira Mini Sling System involves anchoring a midurethral, low-tension tape to the obturator internus muscles bilaterally at the level of the tendinous arc. Success rates in different subsets of patients are still to be defined. This work aims to identify which factors influence the 2-year outcomes of this treatment. Analysis was based on data from a multicenter study. Endpoints for analysis included objective measurements: 1-h pad-weight (PWT), and cough stress test (CST), and questionnaires: International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and Urinary Distress Inventory (UDI)-6. A logistic regression analysis evaluated possible risk factors for failure. In all, 124 female patients with stress urinary incontinence (SUI) underwent treatment with the Ophira procedure. All patients completed 1 year of follow-up, and 95 complied with the 2-year evaluation. Longitudinal analysis showed no significant differences between results at 1 and 2 years. The 2-year overall objective results were 81 (85.3%) patients dry, six (6.3%) improved, and eight (8.4%) incontinent. A multivariate analysis revealed that previous anti-incontinence surgery was the only factor that significantly influenced surgical outcomes. Two years after treatment, women with previous failed surgeries had an odds ratio (OR) for treatment failure (based on PWT) of 4.0 [95% confidence interval (CI) 1.02-15.57). The Ophira procedure is an effective option for SUI treatment, with durable good results. Previous surgeries were identified as the only significant risk factor, though previously operated patients showed an acceptable success rate.

Dielectron Mass Spectra From Au+au Collisions At √[s(nn)]=200 gev.

We report the STAR measurements of dielectron (e(+)e(-)) production at midrapidity (|y(ee)|<1) in Au+Au collisions at √[s(NN)]=200  GeV. The measurements are evaluated in different invariant mass regions with a focus on 0.30-0.76 (ρ-like), 0.76-0.80 (ω-like), and 0.98-1.05 (ϕ-like)   GeV/c(2). The spectrum in the ω-like and ϕ-like regions can be well described by the hadronic cocktail simulation. In the ρ-like region, however, the vacuum ρ spectral function cannot describe the shape of the dielectron excess. In this range, an enhancement of 1.77±0.11(stat)±0.24(syst)±0.33(cocktail) is determined with respect to the hadronic cocktail simulation that excludes the ρ meson. The excess yield in the ρ-like region increases with the number of collision participants faster than the ω and ϕ yields. Theoretical models with broadened ρ contributions through interactions with constituents in the hot QCD medium provide a consistent description of the dilepton mass spectra for the measurement presented here and the earlier data at the Super Proton Synchrotron energies.

Beam-energy Dependence Of Charge Separation Along The Magnetic Field In Au+au Collisions At Rhic.

Local parity-odd domains are theorized to form inside a quark-gluon plasma which has been produced in high-energy heavy-ion collisions. The local parity-odd domains manifest themselves as charge separation along the magnetic field axis via the chiral magnetic effect. The experimental observation of charge separation has previously been reported for heavy-ion collisions at the top RHIC energies. In this Letter, we present the results of the beam-energy dependence of the charge correlations in Au+Au collisions at midrapidity for center-of-mass energies of 7.7, 11.5, 19.6, 27, 39, and 62.4 GeV from the STAR experiment. After background subtraction, the signal gradually reduces with decreased beam energy and tends to vanish by 7.7 GeV. This implies the dominance of hadronic interactions over partonic ones at lower collision energies.

Measurement Of Longitudinal Spin Asymmetries For Weak Boson Production In Polarized Proton-proton Collisions At Rhic.

We report measurements of single- and double-spin asymmetries for W^{±} and Z/γ^{*} boson production in longitudinally polarized p+p collisions at sqrt[s]=510  GeV by the STAR experiment at RHIC. The asymmetries for W^{±} were measured as a function of the decay lepton pseudorapidity, which provides a theoretically clean probe of the proton's polarized quark distributions at the scale of the W mass. The results are compared to theoretical predictions, constrained by polarized deep inelastic scattering measurements, and show a preference for a sizable, positive up antiquark polarization in the range 0.05

Beam Energy Dependence Of Moments Of The Net-charge Multiplicity Distributions In Au+au Collisions At Rhic.

We report the first measurements of the moments--mean (M), variance (σ(2)), skewness (S), and kurtosis (κ)--of the net-charge multiplicity distributions at midrapidity in Au+Au collisions at seven energies, ranging from sqrt[sNN]=7.7 to 200 GeV, as a part of the Beam Energy Scan program at RHIC. The moments are related to the thermodynamic susceptibilities of net charge, and are sensitive to the location of the QCD critical point. We compare the products of the moments, σ(2)/M, Sσ, and κσ(2), with the expectations from Poisson and negative binomial distributions (NBDs). The Sσ values deviate from the Poisson baseline and are close to the NBD baseline, while the κσ(2) values tend to lie between the two. Within the present uncertainties, our data do not show nonmonotonic behavior as a function of collision energy. These measurements provide a valuable tool to extract the freeze-out parameters in heavy-ion collisions by comparing with theoretical models.

Observation Of D0 Meson Nuclear Modifications In Au+au Collisions At Sqrt[s(nn)] = 200 Gev.

We report the first measurement of charmed-hadron (D(0)) production via the hadronic decay channel (D(0) → K(-) + π(+)) in Au+Au collisions at sqrt[s(NN)] = 200 GeV with the STAR experiment. The charm production cross section per nucleon-nucleon collision at midrapidity scales with the number of binary collisions, N(bin), from p+p to central Au+Au collisions. The D(0) meson yields in central Au + Au collisions are strongly suppressed compared to those in p+p scaled by N(bin), for transverse momenta p(T) > 3 GeV/c, demonstrating significant energy loss of charm quarks in the hot and dense medium. An enhancement at intermediate p(T) is also observed. Model calculations including strong charm-medium interactions and coalescence hadronization describe our measurements.

Pharmacokinetic And Pharmacodynamic Evaluation Of A Nanotechnological Topical Formulation Of Lidocaine/prilocaine (nanorap) In Healthy Volunteers.

Nanorap is a new nanotechnological formulation for topical anesthesia composed of lidocaine (2.5%) and prilocaine (2.5%). The present study evaluated the pharmacokinetics (PK) of Nanorap. For the determination of lidocaine and prilocaine in human plasma a new method using high-performance liquid-chromatography coupled to tandem mass spectrometry was developed. Nanorap pharmacodynamic (PD) and its physical proprieties were also evaluated. Nanorap was administered by topical application of 2g to healthy volunteers and blood samples were collected for the PK analysis. The drugs were extracted from plasma by liquid-liquid extraction with ether/hexane (80/20, v/v). The chromatography separation was performed on a Genesis C18 analytical column 4 µm (100 x 2.1 mm i.d.) with a mobile phase of methanol/acetonitrile/water (40/30/30, for lidocaine, and 50/30/20, for prilocaine, v/v/v) + 2 mM of ammonium acetate and ropivacaine as internal standard. The drugs were quantified using a mass spectrometer with an electrospray source in the ESI positive mode (ES+) configured for multiple reaction monitoring. The PD of Nanorap was evaluated with the use of a visual analogue scale. Nanorap was characterized by cryofracture. The chromatography run time was 5.5 min for lidocaine and 3.3 min for prilocaine and the lower limit of quantification was 0.05 ng/mL for both drugs. Mean Cmax was 6.62 and 1.72 ng/mL for lidocaine and prilocaine, respectively. Median Tmax was 6.5 hours for both drugs. Nanocapsules had a mean size of 88nm and mean drug association of 92.5% and 89% for lidocaine and prilocaine, respectively. The PD study showed that Nanorap has a sufficient analgesic effect (>30% reduction in pain) after 10 minutes of application. A new simple, selective and sensitive method for determination of lidocaine and prilocaine in human plasma was developed. Nanorap generated safe plasma levels of the drugs and satisfactory analgesic effect.

ΛΛ Correlation Function In Au+au Collisions At √[s(nn)]=200 gev.

We present ΛΛ correlation measurements in heavy-ion collisions for Au+Au collisions at sqrt[s_{NN}]=200  GeV using the STAR experiment at the Relativistic Heavy-Ion Collider. The Lednický-Lyuboshitz analytical model has been used to fit the data to obtain a source size, a scattering length and an effective range. Implications of the measurement of the ΛΛ correlation function and interaction parameters for dihyperon searches are discussed.

PREDIÇÃO DA ATIVIDADE DE ÁGUA E RELAÇÃO ENTRE A ATIVIDADE DE ÁGUA E A DEPRESSÃO DO PONTO DE CONGELAMENTO DE SUCOS DE FRUTAS

This work proposes to determine the water activity and the freezing point depression of tangerine, pineapple and lemon juices at various concentrations (10-55oBrix) and to achieve a correlation between these properties. The freezing point depression was determined with a LAKTRON cryoscope and common laboratory materials. The water activity was determined with a DECAGON CX-2 hygrometer in the temperature range of 15 to 30oC. With the results, the adjustment to CHEN (1987) water activity prediction equation to non-electrolyte mixtures was verified, through the calculation of the variation coefficient (CV). Being CV smaller than 3% for the proposed model, it can be said that the experimental data have adjusted well to the prediction equation. The water activity and the freezing point depression was correlated for tangerine, pineapple and lemon juices and r2 values were higher than 99%. Therefore, it is possible to obtain the water activity by knowing the freezing point depression of studied juices.

Cladistic analysis of Hemirhipini with establishment of Propalaus gen. nov. (Coleoptera, Elateridae, agrypninae)

This article includes a cladistic analysis of the tribe Hemirhipini. Are included 20 Hemirhipini genera (sensu Casari-Chen 1994), Saltamartinus Casari (1996b) (Hemirhipini), 6 genera excluded from Hemirhipini and kept in Agrypninae (formerly Pyrophorinae) (Casari-Chen 1993) and also, Aphileus Candèze (1857), Pyrophorus Billberg (1820) and Thoramus Sharp (1877). The type-species of the majority of genera and all species of the American genera (except Saltamartinus viduus (Chevrolat 1867)) are included. This analysis demonstrates that 30 genera belong to Hemirhipini: Abiphis Fleutiaux (1926), Alaolacon Candèze (1865), Alaomorphus Hauser (1900), Alaus Eschscholtz (1829), Aliteus Candèze (1857), Anthracalaus Fairmaire (1888), Aphileus Candèze (1857), Austrocalais Neboiss (1967), Calais Castelnau (1836), Catelanus Fleutiaux (1942), Chalcolepidius Eschscholtz (1829), Chalcolepis Candèze (1857), Conobajulus Van Zwaluwenburg (1940), Coryleus Fleutiaux (1942), Cryptalaus Ôhira (1967), Eleuphemus Hyslop (1921), Eumoeus Candèze (1874), Fusimorphus Fleutiaux (1942), Hemirhipus Latreille (1829), Lacais Fleutiaux (1942), Lycoreus Candèze (1857), Mocquerysia Fleutiaux (1899), Neocalais Girard (1971), Pherhimius Fleutiaux (1942), Phibisa Fleutiaux (1942), Propalaus gen. nov., Pseudocalais Girard (1971), Saltamartinus Casari (1996), Tetrigus Candèze (1857) and Thoramus Sharp (1877). The species included in Alaus do not make a monophyletic group and Propalaus gen. nov. is established to include Alaus alicii (Pjatakowa 1941) and A. haroldi (Candèze 1878). A description of Propalaus gen. nov. (type-species: Chalcolepidius haroldi Candèze, 1878) and a new key to Hemirhipini genera are also presented.

Body Mass Index, Cigarette Smoking, and Alcohol Consumption and Cancers of the Oral Cavity, Pharynx, and Larynx: Modeling Odds Ratios in Pooled Case-Control Data

study-specific results, their findings should be interpreted with caution