Efeitos da terapia periodontal na contagem de leucócitos e níveis do fator de crescimento transformador beta no soro de indivíduos com periodontite severa

Tese (doutorado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2015.

Estilos pessoais dos terapeutas e estilos de vinculação

Neste estudo, procurou-se estudar a relação entre estilos pessoais e estilos de vinculação na relação terapêutica, procurando também, identificar outros aspetos que influenciam quer os estilos pessoais quer os estilos de vinculação duma amostra de psicoterapeutas. Esta amostra foi constituída por 40 licenciados em Psicologia Clínica, de ambos os sexos, com diferentes anos de experiência profissional. Os instrumentos utilizados foram o Questionário do Estilo pessoal (EPT) e a Escala de Vinculação de Adultos (EVA). Os resultados apontaram para uma associação entre a função instrutiva do EPT e o estilo de vinculação (terapeutas rígidos apresentam um estilo de vinculação ambivalente, enquanto que os terapeutas flexíveis apresentam um estilo de vinculação seguro), e entre algumas das funções do EPT com a orientação teórica, o grupo etário dos clientes e o género dos terapeutas. Conclui-se que a forma como os terapeutas estabelecem e regulam as suas sessões, está associada ao estilo de vinculação. ABSTRACT: ln this study, the priority goal was to identify which type of relationship exist between personnel styles and attachment styles in the therapeutic relationship; still point a characterization and a recognition of what aspects that can influence it, and then analyse it. The sample were constituted by 40 psychotherapists, they have a licenciature degree in clinical psychology, and the years of professional experience or the duration that they have the degree don't matter. The questionnaire EPT-C and the Adult attachment Scale-R (AAS-R). The results point to the association between the instructive function and attachment styles, as to the EPT-C functions with theoric orientation, age groups of clients, and therapists genres. The therapists that are rigids show a ambivalent style; but therapists flexible shows a secure style of attachment. lndeed the way as therapists stablish and regulate their sessions, is associated to the attachment style.

Estrategias de afrontamiento familiar que los padres utilizan ante las pérdidas afectivas de los niños por separación

El siguiente estudio tiene como objetivo principal describir las estrategias de afrontamiento familiar que los padres utilizan ante las pérdidas afectivas de los niños por separación, con fundamento en el modelo estructural de Salvador Minuchín. En esta investigación participaron cinco familias monoparentales. El enfoque de la investigación es cualitativo; se aplicó la escala F-Copes para identificar cómo la familia maneja sus problemas y afronta las demandas que surgen de la separación o divorcio, seguido de una entrevista semiestructurada, la misma que demostró que cuando surge la separación conyugal trae uno o varios cambios en la estructura familiar y, en la relación entre los subsistemas los individuos modifican sus rutinas y se crea una nueva organización. El estudio muestra cómo las potencialidades de estas familias avanzan tejiendo internamente estrategias adaptativas que regulan el equilibrio emocional y relacional del sistema hacia las vicisitudes o desafíos del ciclo vital y de la vida misma; que para afrontar las pérdidas afectivas, uno de los mecanismos de afrontamiento es la alianza entre hermanos, lo que contribuye a una estrategia funcional permitiendo una relación benéfica con vínculos asertivos. Concluyendo que el contexto que rodea al niño es esencial para el desarrollo de estrategias de afrontamiento durante la infancia y las etapas subsiguientes.

Relação entre as memórias autobiográficas e relações interpessoais e de vinculação: Alterações de humor nas memórias autobiográficas

Dissertação de Mestrado apresentada no ISPA - Instituto Universitário para obtenção de grau de Mestre na especialidade de Psicologia Clínica

Memórias autobiográficas voluntárias e involuntárias: Relações com a vinculação, as relações interpessoais e a ansiedade

Dissertação de Mestrado apresentada no ISPA – Instituto Universitário para obtenção de grau de Mestre na especialidade de Psicologia Clínica

Retaining formal volunteers in volunteer based organizations

Abstract Problem Formal Volunteers in volunteer based organizations drop out at a fast pace due to many reasons like lack of interest what they are doing, conflict among volunteers, lack of motivation, job dissatisfaction due to prolonged volunteering etc.  which is causing to improper functioning of these organizations and reaches a point where these volunteer based organizations find it difficult to function properly. The author in this study tries to address this particular issue of this drop out of formal volunteers. Purpose The purpose of this study is to explore the factors which helps in the retention of formal volunteers in a volunteer based organization for a longer period. Method The research in this paper is done in a qualitative way with primary data collected in the form of participant observation and open interview in two voluntary organizations. The collected data is analyzed in content analysis. The secondary data is collected in the form of necessary documents provided by the participating organizations. Results Many factors were found to influence retention of volunteers namely Job satisfaction, Motivation, Public Service Motivation, Organizational Commitment, Mission Attachment, Work load, Relationship with Coworkers, Justice of Organization, Flexible Timing, Training & Orientation.  Conclusions Recommendations to improve retention is mentioned and a future model is also proposed. The result obtained from this research can be generalized to other form of small scale volunteer organizations where the major employees are formal volunteers.

New prophylactic and therapeutic treatments to combat pathogenic Enterohaemorrhagic Escherichia coli

Bacterial diarrhoeal diseases have significant influence on global human health, and are a leading cause of preventable death in the developing world. Enterohaemorrhagic Escherichia coli (EHEC), pathogenic strains of E. coli that carry potent toxins, have been associated with a high number of large-scale outbreaks caused by contaminated food and water sources. This pathotype produces diarrhoea and haemorrhagic colitis in infected humans, and in some patients leads to the development of haemolytic uremic syndrome (HUS), which can result in mortality and chronic kidney disease. A major obstacle to the treatment of EHEC infections is the increased risk of HUS development that is associated with antibiotic treatment, and rehydration and renal support are often the only options available. New treatments designed to prevent or clear E. coli infections and reduce symptoms of illness would therefore have large public health and economic impacts. The three main aims of this thesis were: to explore mouse models for pre-clinical evaluation in vivo of small compounds that inhibit a major EHEC colonisation factor, to assess the production and role of two proteins considered promising candidates for a broad-spectrum vaccine against pathogenic E. coli, and to investigate a novel compound that has recently been identified as a potential inhibitor of EHEC toxin production. As EHEC cannot be safely tested in humans due to the risk of HUS development, appropriate small animal models are required for in vivo testing of new drugs. A number of different mouse models have been developed to replicate different features of EHEC pathogenesis, several of which we investigated with a focus on colonisation mediated by the Type III Secretion System (T3SS), a needle-like structure that translocates bacterial proteins into host cells, resulting in a tight, intimate attachment between pathogen and host, aiding colonisation of the gastrointestinal tract. As E. coli models were found not to depend significantly on the T3SS for colonisation, the Citrobacter rodentium model, a natural mouse pathogen closely related to E. coli, was deemed the most suitable mouse model currently available for in vivo testing of T3SS-targeting compounds. Two bacterial proteins, EaeH (an outer membrane adhesin) and YghJ (a putative secreted lipoprotein), highly conserved surface-associated proteins recently identified as III protective antigens against E. coli infection of mice, were explored in order to determine their suitability as candidates for a human vaccine against pathogenic E. coli. We focused on the expression and function of these proteins in the EHEC O157:H7 EDL933 strain and the adherent-invasive E. coli (AIEC) LF82 strain. Although expression of EaeH by other E. coli pathotypes has recently been shown to be upregulated upon contact with host intestinal cells, no evidence of this upregulation could be demonstrated in our strains. Additionally, while YghJ was produced by the AIEC strain, it was not secreted by bacteria under conditions that other YghJ-expressing E. coli pathotypes do, despite the AIEC strain carrying all the genes required to encode the secretion system it is associated with. While our findings indicate that a vaccine that raises antibodies against EaeH and YghJ may have limited effect on the EHEC and AIEC strains we used, recent studies into these proteins in different E. coli pathogens have suggested they are still excellent candidates for a broadly effective vaccine against E. coli. Finally, we characterised a small lead compound, identified by high-throughput screening as a possible inhibitor of Shiga toxin expression. Shiga toxin production causes both the symptoms of illness and development of HUS, and thus reduction of toxin production, release, or binding to host receptors could therefore be an effective way to treat infections and decrease the risk of HUS. Inhibition of Shiga toxin production by this compound was confirmed, and was shown to be caused by an inhibitory effect on activation of the bacterial SOS response rather than on the Shiga toxin genes themselves. The bacterial target of this compound was identified as RecA, a major regulator of the SOS response, and we hypothesise that the compound binds covalently to its target, preventing oligomerisation of RecA into an activated filament. Altogether, the results presented here provide an improved understanding of these different approaches to combating EHEC infection, which will aid the development of safe and effective vaccines and anti-virulence treatments against EHEC.

Ideación suicida y desesperanza en pacientes con cáncer

El objetivo de la presente investigación fue identificar la relación entre ideación suicida y desesperanza en 160 pacientes con cáncer. La ideación suicida se midió a través de dos ítems de una entrevista semiestructurada, la escala de ideación suicida (ISS), el ítem 9 del inventario de depresión de Beck (BDI-IA). La desesperanza se midió con la escala de desesperanza de Beck (BHS). Los resultados obtenidos indicaron una relación significativa (p=.000) entre ideación suicida y desesperanza; una prevalencia de ideación suicida en los pacientes con cáncer entre 4.4% y 13.8% y de riesgo de suicidio entre 5.6% y 30.6%; y algún grado de desesperanza en 31.9 % de los participantes. De acuerdo con lo anterior, se confirma que existe relación entre la desesperanza y la ideación suicida en pacientes oncológicos adultos. Adicionalmente, que estas variables están presentes en los pacientes y que ameritan atención en la intervención interdisciplinaria.

Aproximaciones a mindfulness en la psicología contemporánea

Este trabajo es una revisión de literatura que abarca una selección de artículos disponibles en bases de datos especializadas y publicados en el periodo comprendido entre los años 2006 a 2016 para artículos científicos y entre los años 2000 a 2016 para libros. En total se revisaron: 1 tesis doctoral, 1 tesis magistral, 111 artículos y 9 libros o capítulos de libros. Se presentan diversas definiciones de mindfulness y formas de conceptualizarla, sus mecanismos de acción, sus enfoques psicoterapéuticos predominantes, los efectos de su práctica estable, sus principales campos de acción y la importancia de la formación de los docentes que imparten la práctica. Finalmente se presentan algunas conclusiones acerca del diálogo entre la literatura psicológica sobre mindfulness y algunas de las concepciones de la tradición budista en torno a la meditación.

Tornar-se psicoterapeuta: Expectativas, preocupações e construção do estilo pessoal do terapeuta

O presente estudo tem como objectivos primordiais, identificar as expectativas e as preocupações dos estagiários de psicologia em relação ao seu futuro papel de psicoterapeuta e perceber se existe relação entre estas e os Estilos de Vinculação. A amostra é composta por 95 estagiários de psicologia clínica e educacional, na sua maioria mulheres, com idades compreendidas entre os 22 e os 60 anos e provenientes de 7 Universidades do País. Os mesmos foram sujeitos à aplicação do Questionário de Estilo Pessoal do Terapeuta (EPT-C}, da Escala de Vinculação do Adulto (EVA) e confrontados com uma questão relativa aos seus medos. Com base nos resultados concluímos que os estagiários se perspectivam de um modo idealizado no futuro, preocupando-se de um modo geral com as suas competências. A relação encontrada entre os Estilos de Vinculação e algumas componentes do Estilo Pessoal do Terapeuta apesar de significativa carece de mais desenvolvimentos. /ABSTRACT: The present work has two main purposes: to identify the expectations and worries of the psychology trainees towards their future as a psychotherapist and two conceive if there is any connection between them and the Attachment Styles. The sample is formed by 95 clinic and educational psychology trainees, being the greatest part of them women between 22 and 60 years old from 7 Universities all over the country. They have been studied under the Personal Style of the Therapist, the Adult Attachment Scale-R and, later on, they were confronted by a question concerning their fears. Based on the results, we conclude that the trainee’s perspective themselves, as for the future is concerned ire an idealistic way, worrying, in general, about their skills. The relation found between the Attachment Styles and some elements of the Personal Style of the Therapist although it is significate, needs more development.

Announcing Motherhood

Introduction: Pregnancy is associated with experiences that integrated socio-cultural contexts of space and time, bring changes in family and/or maternal-fetal relationship. Parenthood is a generational task, and one of the most complex in humans. Aimo: To describe the construction of motherhood. Method: Cross-sectional qualitative study. We used the interview technique. Convenience sample of 10 pregnant women at the end of 3rd trimester. Results: The analysis of the narrative reveals four categories: a) conceiving pregnancy idea, b) imagining maternity, c) claiming herself through pregnancy and d) announcing attachment Conclusion: pregnant women essentially express positive and tipical feelings of pregnancy, seeming an healthy evolution. The transition to parenthood is underway, as well as a developing performance to the best role.

Structural Connectivity Of The Default Mode Network And Cognition In Alzheimer׳s Disease.

Disconnectivity between the Default Mode Network (DMN) nodes can cause clinical symptoms and cognitive deficits in Alzheimer׳s disease (AD). We aimed to examine the structural connectivity between DMN nodes, to verify the extent in which white matter disconnection affects cognitive performance. MRI data of 76 subjects (25 mild AD, 21 amnestic Mild Cognitive Impairment subjects and 30 controls) were acquired on a 3.0T scanner. ExploreDTI software (fractional Anisotropy threshold=0.25 and the angular threshold=60°) calculated axial, radial, and mean diffusivities, fractional anisotropy and streamline count. AD patients showed lower fractional anisotropy (P=0.01) and streamline count (P=0.029), and higher radial diffusivity (P=0.014) than controls in the cingulum. After correction for white matter atrophy, only fractional anisotropy and radial diffusivity remained significantly lower in AD compared to controls (P=0.003 and P=0.05). In the parahippocampal bundle, AD patients had lower mean and radial diffusivities (P=0.048 and P=0.013) compared to controls, from which only radial diffusivity survived for white matter adjustment (P=0.05). Regression models revealed that cognitive performance is also accounted for by white matter microstructural values. Structural connectivity within the DMN is important to the execution of high-complexity tasks, probably due to its relevant role in the integration of the network.

Endoscopic Endonasal Transsphenoidal Resection Of Pituitary Adenomas: Preliminary Evaluation Of Consecutive Cases.

Endoscopic endonasal transsphenoidal surgery has gained increasing acceptance by otolaryngologists and neurosurgeons. In many centers throughout the world, this technique is now routinely used for the same indications as conventional microsurgical technique for pituitary tumors. To present a surgical experience of consecutive endoscopic endonasal trans-sphenoidal resections of pituitary adenomas. In this study, consecutive patients with pituitary adenomas submitted to endoscopic endonasal pituitary surgery were evaluated regarding the rate of residual tumor, functional remission, symptoms relief, complications, and tumor size. Forty-seven consecutive patients were evaluated; 17 had functioning adenomas, seven had GH producing tumors, five had Cushing's disease, and five had prolactinomas. Of the functioning adenomas, 12 were macroadenomas and five were microadenomas; 30 cases were non-functioning macroadenomas. Of the patients with functioning adenomas, 87% improved. 85% of the patients with visual deficits related to optic nerve compression progressed over time. Most of the patients with complaints of headaches improved (76%). Surgical complications occurred in 10% of patients, which included with two carotid lesions, two cerebrospinal fluid leaks, and one death of a patient with a previous history of complications. Endoscopic endonasal pituitary surgery is a feasible technique, yielding good surgical and functional outcomes, and low morbidity.

Delays In Receiving Obstetric Care And Poor Maternal Outcomes: Results From A National Multicentre Cross-sectional Study.

The vast majority of maternal deaths in low-and middle-income countries are preventable. Delay in obtaining access to appropriate health care is a fairly common problem which can be improved. The objective of this study was to explore the association between delay in providing obstetric health care and severe maternal morbidity/death. This was a multicentre cross-sectional study, involving 27 referral obstetric facilities in all Brazilian regions between 2009 and 2010. All women admitted to the hospital with a pregnancy-related cause were screened, searching for potentially life-threatening conditions (PLTC), maternal death (MD) and maternal near-miss (MNM) cases, according to the WHO criteria. Data on delays were collected by medical chart review and interview with the medical staff. The prevalence of the three different types of delays was estimated according to the level of care and outcome of the complication. For factors associated with any delay, the PR and 95%CI controlled for cluster design were estimated. A total of 82,144 live births were screened, with 9,555 PLTC, MNM or MD cases prospectively identified. Overall, any type of delay was observed in 53.8% of cases; delay related to user factors was observed in 10.2%, 34.6% of delays were related to health service accessibility and 25.7% were related to quality of medical care. The occurrence of any delay was associated with increasing severity of maternal outcome: 52% in PLTC, 68.4% in MNM and 84.1% in MD. Although this was not a population-based study and the results could not be generalized, there was a very clear and significant association between frequency of delay and severity of outcome, suggesting that timely and proper management are related to survival.

[insomnia Symptoms, Daytime Naps And Physical Leisure Activities In The Elderly: Fibra Study Campinas].

The practice of physical activities contributes to reducing the risk of chronic diseases and improves sleep patterns in the elderly. This research aimed to investigate the association between insomnia symptoms and daytime nap and the participation in physical leisure activities in elderly community residents. Data from the Studies Network of the Fragility in Brazilian Elderly (Campinas site), were used. Information from 689 elderly was analyzed, regarding sociodemographic characterization, physical leisure activity, occurrence of daytime napping and its duration, symptoms of insomnia and use of sleep medication. A significant association was found between the practice of walking and the daytime nap of short duration. Studies indicate that a short nap can benefit the quality of sleep and health of the elderly. Therefore, promoting the practice of walking can be a nursing intervention that favors the sleep patterns of the elderly.