Software de adquisición de imágenes y reconocimiento óptico de caracteres para Android

El presente proyecto parte de la propuesta realizada por la empresa Tempos21 donde se recoge la necesidad de crear una librería de reconocimiento óptico de caracteres para la plataforma Android. Esta librería podrá ser utilizada por diferentes aplicaciones ejecutadas en terminales móviles que cuenten con este sistema operativo.

A New Imaging Software To Evaluate The Centration Of Capsulorhexis And Intraocular Lens (IOL) After Cataract Surgery

Purpose: IOL centration and stability after cataract surgery is of high interest for cataract surgeons and IOL-producing companies. We present a new imaging software to evaluate the centration of the rhexis and the centration of the IOL after cataract surgery.Methods: We developed, in collaboration with the Biomedical Imaging Group (BIG), EPFL, Lausanne, a new working tool in order to assess precisely outcomes after IOL-implantation, such as ideal capsulorhexis and IOL-centration. The software is a plug-in of ImageJ, a general-purpose image processing and image-analysis package. The specifications of this software are: evaluation of the rhexis-centration and evaluation the position of the IOL in the posterior chamber. The end points are to analyze the quality of the centration of a rhexis after cataract surgery, the deformation of the rhexis with capsular bag retraction and the centration of the IOL after implantation.Results: This software delivers tools to interactively measure the distances between limbus, IOL and capsulorhexis and its changes over time. The user is invited to adjust nodes of three radial curves for the limbus, rhexis and the optic of the IOL. The radial distances of the curves are computed to evaluate the IOL implantation. The user is also able to define patterns for ideal capsulorhexis and optimal IOL-centration. We are going to present examples of calculations after cataract surgery.Conclusions: Evaluation of the centration of the rhexis and of the IOL after cataract surgery is an important end point for optimal IOL implantation after cataract surgery. Especially multifocal or accommodative lenses need a precise position in the bag with a good stability over time. This software is able to evaluate these parameters just after the surgery but also its changes over time. The results of these evaluations can lead to an optimizing of surgical procedures and materials.

Portafolio selection with skewness: a comparison of methods and a generalized two fund separation result

This contribution compares existing and newly developed techniques for geometrically representing mean-variances-kewness portfolio frontiers based on the rather widely adapted methodology of polynomial goal programming (PGP) on the one hand and the more recent approach based on the shortage function on the other hand. Moreover, we explain the working of these different methodologies in detail and provide graphical illustrations. Inspired by these illustrations, we prove a generalization of the well-known two fund separation theorem from traditionalmean-variance portfolio theory.

Migración de servicios críticos: de plataformas propietarias a software libre

El objetivo principal del presente trabajo pretende demostrar el potencial del software libre frente al software propietario que actualmente utiliza la empresa Systemum.

Software para la representación gráfica a la solución de ruteo y carga de vehículos en algoritmo de tipo 2L-CVRP

El siguiente artículo presenta el trabajo realizado en la creación de una aplicación de software libre que representa gráficamente las rutas generadas y la distribución de los elementos transportados en el interior de un vehículo de carga.

Impact of Pre-Existing Immunity on the Selection of Rare Adenovirus Vector Candidates: Implications for HIV Vaccine Development

Background: Adenovirus serotype 5 (Ad5) phase IIb vaccine trial (STEP) was prematurely stopped due to a lack of efficacy and two-fold higher incidence of HIV infection among Ad5 seropositive vaccine recipients. We have recently demonstrated that Ad5 immune complexes (Ad5 ICs)-mediated activation of the dendritic cell (DC)-T cell axis was associated with the enhancement of HIV infection in vitro. Although the direct role of Ad5 neutralizing antibodies (NAbs) in the increase of HIV susceptibility during the STEP trial is still under debate, vector-specific NAbs remain a major hurdle for vector-based gene therapies or vaccine strategies. To surmount this obstacle, vectors based on ''rare'' Ad serotypes including Ad6, Ad26, Ad36 and Ad41 were engineered.Methods: The present study aimed to determine whether Ad ICmediated DC maturation could be circumvented using these Advector candidates.Results: We found that all Ad vectors tested forming ICs with plasma containing serotype-specific NAbs had the capacity to 1) mature human DCs as monitored by the up-regulation of costimulatory molecules and the release of pro-inflammatory cytokines (TNF-a), via the stabilization of Ad capsid at endosomal but not lysosomal pH rendering Ad DNA/TLR9 interactions possible and 2) potentiate Ad-specific CD4 and CD8 T cell responses.Conclusion: In conclusion, despite a conserved DC maturation potential, the low prevalence of serotype-specific NAbs renders rare Ad vectors attractive for vaccine strategies.

Increased frequency of regulatory T cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients with rapamycin.

The currently available immunosuppressive agents applied in human transplantation medicine are highly potent in the protection from acute allograft rejection. However, long-term allograft survival is still poor as these drugs fail to sufficiently prevent chronic allograft rejection. Naturally occurring regulatory T cells have been postulated as the key players to establish long-lasting transplantation tolerance. Thus, the development of immunosuppressive regimens which shift the pathological balance of cytopathic versus regulatory T cells of human allograft recipients towards a protective T-cell composition is a promising approach to overcome limitations of current transplantation medicine. Thirty-three patients that received rapamycin (RPM) or calcineurin inhibitor treatment following lung transplantation were included and their T-cell compartments analysed. Twelve healthy volunteers without history of lung disease served as controls. In this article, we show that treatment of human lung transplant recipients with RPM is associated with an increased frequency of regulatory T cells, as compared with treatment with calcineurin inhibitors or to healthy controls. Moreover, regulatory T cells during treatment with RPM were CD62Lhigh, a phenotype that displayed an enhanced immunosuppressive capacity ex vivo. Our data support the use of RPM in human lung transplant recipients and undertaking of further prospective studies evaluating its impact on allograft and patient survival.

Implantació d'un ERP i una plataforma e-commerce de software lliure per al desenvolupament web d'una empresa

Aquest projecte constitueix la introducció d'un sistema d'informació a una PIME catalana. Incorporant dos grans i potents funcionalitats i serveis a l'empresa: la venta online mitjançant un e-commerce i la gestió de la informació i productes que hi ha a l'empresa mitjançant un ERP.

A genetic algorithm to ensemble feature selection

We are going to implement the "GA-SEFS" by Tsymbal and analyse experimentally its performance depending on the classifier algorithms used in the fitness function (NB, MNge, SMO). We are also going to study the effect of adding to the fitness function a measure to control complexity of the base classifiers.

gcodeml: A Grid-enabled Tool for Detecting Positive Selection in Biological Evolution

One of the important questions in biological evolution is to know if certain changes along protein coding genes have contributed to the adaptation of species. This problem is known to be biologically complex and computationally very expensive. It, therefore, requires efficient Grid or cluster solutions to overcome the computational challenge. We have developed a Grid-enabled tool (gcodeml) that relies on the PAML (codeml) package to help analyse large phylogenetic datasets on both Grids and computational clusters. Although we report on results for gcodeml, our approach is applicable and customisable to related problems in biology or other scientific domains.

RestKiosk : Software d'autoservei per a restauració

Primera versió d'una aplicació per a establiments de restauració que té com a finalitat oferir als clients la possibilitat de fer les comandes de forma autònoma.

Avaliação de alunos e professores acerca do software "Sinais Vitais"

Este artigo teve por objetivo levantar as opiniões de alunos e professores sobre o software "Sinais Vitais". O trabalho foi desenvolvido no Departamento de Enfermagem da Universidade Federal do Ceará. Trabalhou-se com um total de seis alunos e três professores, os quais foram submetidos a uma entrevista após a utilização do software. As entrevistas geraram dez categorias, as quais foram separadas em dois temas: Características que estimularam a utilização do software "Sinais Vitais" e Software educacionalmente correto. Concluiu-se que os professores valorizaram a correção do conteúdo, enquanto os alunos enfocaram mais a dinâmica do programa.

Creació d’un visor web basat en software lliure per al Consorci d’Ardenya-Cadiretes

En aquest treball es pretén explicar el procés metodològic que s'ha seguit per a crear una eina informàtica de visualització de dades "online" per al Consorci d'Ardenya – Cadiretes. Inicialment s'explica el context en el que es desenvolupa el projecte, com a conveni de col·laboració en pràctiques, per a realitzar el treball de final del Màster en Tecnologies de la Informació Geogràfica, en la seva tretzena edició. S'explica també la situació de l'entitat col·laboradora del projecte, el consorci d'Ardenya – Cadiretes. Els objectius que es fixen al projecte són els de generar aquest visor amb eines de software lliure, de manera que el cost de producció sigui el menor possible. També es pretén crear una aplicació de senzill ús i que resulti atractiva per al client web. Es repassen els diferents aspectes tècnics i funcionals que ha de tenir en compte el projecte, per tal que aquest es pugui desenvolupar de forma correcte. Es tracten temes com el tipus de programari que s'ha de fer servir i per que unes aplicacions es consideren més oportunes que d'altres per a treballar tasques concretes del propi projecte. A través de la metodologia seguida en el projecte es repassa el dia a dia que s'ha anat seguint durant el projecte, des de l'inici en el que s'instal·laven els diferents programes necessaris fins al final de l'escriptura del codi de programació, passant per l'edició de les dades geogràfiques o la càrrega d'aquestes al servidor de mapes