Electrocutaneous Stimulation: Principles, Applications and Challenges

IRR Poster 2012

Genomic architecture of adaptive color pattern divergence and convergence in Heliconius butterflies

Identifying the genetic changes driving adaptive variation in natural populations is key to understanding the origins of biodiversity. The mosaic of mimetic wing patterns in Heliconius butterflies makes an excellent system for exploring adaptive variation using next-generation sequencing. In this study, we use a combination of techniques to annotate the genomic interval modulating red color pattern variation, identify a narrow region responsible for adaptive divergence and convergence in Heliconius wing color patterns, and explore the evolutionary history of these adaptive alleles. We use whole genome resequencing from four hybrid zones between divergent color pattern races of Heliconius erato and two hybrid zones of the co-mimic Heliconius melpomene to examine genetic variation across 2.2 Mb of a partial reference sequence. In the intergenic region near optix, the gene previously shown to be responsible for the complex red pattern variation in Heliconius, population genetic analyses identify a shared 65-kb region of divergence that includes several sites perfectly associated with phenotype within each species. This region likely contains multiple cis-regulatory elements that control discrete expression domains of optix. The parallel signatures of genetic differentiation in H. erato and H. melpomene support a shared genetic architecture between the two distantly related co-mimics; however, phylogenetic analysis suggests mimetic patterns in each species evolved independently. Using a combination of next-generation sequencing analyses, we have refined our understanding of the genetic architecture of wing pattern variation in Heliconius and gained important insights into the evolution of novel adaptive phenotypes in natural populations.

Transcutaneous electrical nerve stimulation and primary dysmenorrhea: a case report

Primary dysmenorrhea is pelvic pain during the menstrual cycle. The A delta and C fibers aresensitized by the increased release of prostaglandins and leukotrienes, thus causing pain. TransElectric Nerve Stimulation (TENS) is a physiotherapeutic strategy that mitigatespain sensation. Objective: The aim of this paper is to present six cases of women in childbearingage who were diagnosed with primary dysmenorrhea and received transcutaneous electricnerve stimulation. Materials and methods: A type of study, case report, was conducted with sixwomen between 15 and 25 years of age with medical diagnosis of primary dysmenorrhea. Weassessed pain intensity utilizing the visual analogue pain scale and located the pain by usinga pain test map. Results: Pain intensity decreased in all treated women. Conclusion: Transcutaneouselectric nerve stimulation (TENS) is a physiotherapeutic strategy that mitigates painsensation. We conclude that high frequency TENSis a safe noninvasive modality to achievereduction of pain in primary dysmenorrhea.

The pattern of fall of serum bilirubin after operative relief of obstructive jaundice. A preliminary report

This is the beginning of a prospective study on patients who have obstructive jaundice to see how the serum bilirubin falls after operative relief of the obstruction. Seven of such patients have been studied; four had carcinoma of the head of the pancreas while the other three had choledocholithiasis. The patients with carcinoma had relief of the jaundice through a biliary-enteric anastomosis and those with common bile duct stones had choledochotomy with stone extraction which was completed with insertion of a T-tube. Serial bilirubin estimations were then performed post-operatively to chart the pattern and rate of descent of this in each patient. Our observations suggest that the pattern of fall of serum bilirubin after successful decompression of the extra-hepatic biliary tree exhibit a distinct pattern regardless of the surgical procedure performed for the relief of the obstruction.

An estimation of the pattern of diffusion of mobile phones: the case of Colombia

In this paper we find that the diffusion pattern of mobile telephony in Colombia can be best characterised as following a Logistic curve. Although in recent years the rate of growth of mobile phone subscribers has started to slow down, we find evidence that there is still room for further expansion as the saturation level is expected to be reached in five years time. The estimated saturation level is consistent with some individuals possessing more than one mobile device.

The crime kuznets curve

We document the existence of a Crime Kuznets Curve in US states since the 1970s. As income levels have risen, crime has followed an inverted U-shaped pattern, first increasing and then dropping. The Crime Kuznets Curve is not explained by income inequality. In fact, we show that during the sample period inequality has risen monotonically with income, ruling out the traditional Kuznets Curve. Our finding is robust to adding a large set of controls that are used in the literature to explain the incidence of crime, as well as to controlling for state and year fixed effects. The Curve is also revealed in nonparametric specifications. The Crime Kuznets Curve exists for property crime and for some categories of violent crime.

La madurez lectográfica y los tests ABC-Reversal, profilaxis de la dislexia.

Conocer el momento en el que el niño alcanza la madurez necesaria para comenzar el aprendizaje de la lectura, ya que parte de los fracasos y retrasos en el aprendizaje de la lectura vienen dados por la inadecuación de este aprendizaje y el momento madurativo del niño.. La muestra ha constado de 120 niños de Educación Preescolar de dos Colegios, uno nacional y el otro privado.. Experimental.. Para realizar este estudio se han empleado dos tipos de tests: El ABC y Reversal. . Experimental, en la que se ha llevado a cabo un estudio estadístico, hallando las puntuaciones típicas, puntuaciones directas, estudio de las medias y por último las correlaciones entre ambos tests. . Las conclusiones a las que se ha llegado con este estudio son las siguientes: Para afrontar el aprendizaje de la lectura se necesita una edad determinada, llamada de madurez lectora que es específica de cada niño ya que no existe una relación entre la edad de madurez lectora y la edad cronológica. Desde otro punto de vista, una inteligencia alta o normal unida al fracaso en el reversal Test y a algunas pruebas del test ABC, indica existencia de trastornos relacionados con la estructuración espacial y la capacidad perceptiva. A su vez, la madurez para la lectura puede favorecerse y adelantarse, incluso, mediante el desarrollo adecuado de los factores fisiológicos, psicológicos y socio-ambientales que están implicados en el aprendizaje de la lectoescritura. Los trastornos lectores llamados dislexias pueden prevenirse si se respetan los niveles de madurez de cada niño y si se desarrollan normalmente los factores que pueden originarlas..

Writting simple poems : pattern poetry for language acquisition.

Muestra a los profesores cómo pueden utilizar escribir poesía para enseñar y reforzar el vocabulario, la estructura y las partes de la oración, la puntuación, así como otras reglas de la gramática y la escritura. Para cualquier edad o nivel de fluidez, puede ser utilizado como lengua extranjera, o para maestros bilingües como un complemento a su programa de escritura. La primera parte del libro se centra en la metodología y ofrece sugerencias para la forma de integrar la poesía escrita con el plan de estudios. La segunda parte del libro contiene veinticinco modelos de poemas y muestras de poesía escritos por estudiantes de diversos idiomas y edades. La tercera parte del libro ofrece un índice y un glosario de términos gramaticales.

Brilliant activities for stretching gifted and talented children : open-ended mental stimulation activities.

Manual que ayuda a padres y profesores a prestar a los niños superdotados y con talento la estimulación mental que necesitan. En la primera parte se hacen comentarios, teorías, por ejemplo, la taxonomía de Bloom, y conceptos relacionados con la creatividad, el aprendizaje y la enseñanza. La segunda parte ofrece una selección de actividades para toda la clase: rompecabezas y ejercicios entretenidos de matemáticas. La tercera parte proporciona entretenimientos de composición abierta, ejercicios independientes para los alumnos. Todas las actividades son fotocopiables. Aunque escrito principalmente para alumnos excepcionales hasta la edad de once años, este recurso presenta enfoques e ideas que pueden aplicarse a cualquier alumno y a cualquier situación de enseñanza.

Layers of generality and types of generalization in pattern activities. 'Niveles de generalidad y tipos de generalizaciones en actividades de patrones'.

Resumen basado en el de la publicación

The distributed nature of pattern generalization

Resumen tomado de la publicaci??n