On the depth of blowup algebras of ideals with analytic deviation one

Let I be an ideal in a local Cohen-Macaulay ring (A, m). Assume I to be generically a complete intersection of positive height. We compute the depth of the Rees algebra and the form ring of I when the analytic deviation of I equals one and its reduction number is also at most one. The formu- las we obtain coincide with the already known formulas for almost complete intersection ideals.

Borcherds products and arithmetic intersection theory on Hilbert modular surfaces

We prove an arithmetic version of a theorem of Hirzebruch and Zagier saying that Hirzebruch-Zagier divisors on a Hilbert modular surface are the coefficients of an elliptic modular form of weight 2. Moreover, we determine the arithmetic selfintersection number of the line bundle of modular forms equipped with its Petersson metric on a regular model of a Hilbert modular surface, and we study Faltings heights of arithmetic Hirzebruch-Zagier divisors.

Bounds on multisecant lines

The purpose of this paper is two fold. First, we give an upper bound on the orderof a multisecant line to an integral arithmetically Cohen-Macaulay subscheme in Pn of codimension two in terms of the Hilbert function. Secondly, we givean explicit description of the singular locus of the blow up of an arbitrary local ring at a complete intersection ideal. This description is used to refine standardlinking theorem. These results are tied together by the construction of sharp examples for the bound, which uses the linking theorems.

The effects of physiologically plausible connectivity structure on local and global dynamics in large scale brain models.

Functionally relevant large scale brain dynamics operates within the framework imposed by anatomical connectivity and time delays due to finite transmission speeds. To gain insight on the reliability and comparability of large scale brain network simulations, we investigate the effects of variations in the anatomical connectivity. Two different sets of detailed global connectivity structures are explored, the first extracted from the CoCoMac database and rescaled to the spatial extent of the human brain, the second derived from white-matter tractography applied to diffusion spectrum imaging (DSI) for a human subject. We use the combination of graph theoretical measures of the connection matrices and numerical simulations to explicate the importance of both connectivity strength and delays in shaping dynamic behaviour. Our results demonstrate that the brain dynamics derived from the CoCoMac database are more complex and biologically more realistic than the one based on the DSI database. We propose that the reason for this difference is the absence of directed weights in the DSI connectivity matrix.

Topological computation of local cohomology multiplicities.

We express the Lyubeznik numbers of the local ring of a complex isolated singularity in terms of Betti numbers of the associated real link.

Con la secularización «se abrió el campo; el que quería venía». La formación de un grupo dirigente en el ámbito local boliviano, 1938/39-1948

Objetivo del artículo es estudiar los cambios más significativos producidos en la región de Guarayos (Noroeste del departamento de Santa Cruz, Bolivia) como consecuencia de la secularización de las misiones franciscanas en la zona, aprobada en 1938/39, y la implantación de la Delegación Nacional de Guarayos encargada de completar el proceso de incorporación de la población guaraya a la «nacionalidad». En particular, se analiza el papel desempeñado por los «administradores », nuevos «gestores» de los territorios y bienes que entre 1939 y 1948 detentaron todo el poder en cada uno de los poblados y fueron los responsables principales de la decadencia económica y despoblación de la región con la connivencia de sus superiores jerárquicos y la incapacidad del Estado para hacerse presente en la convulsa política boliviana del período marcada por continuados golpes militares.

Conversando con Eduardo Sevilla Guzmán. De la Sociología Rural a la Agroecología: la revalorización del conocimiento local como constante

Eduardo Sevilla Guzmán il·lustra l'especificitat de vàries disciplines centrades en el medi rural a partir de la seva pròpia experiència. Tal i com explica en l'entrevista, la seva deriva cap a les Ciències Socials es degué a la necessitat de sostreure's al domini que els interessos de latifundistes i multinacionals exercien sobre la recerca en l'escola d'enginyers on treballava. Més endavant, la necessitat de cercar una alternativa al que es coneix com agricultura "convencional" el dugué a focalitzar la seva atenció en l'estudi d'altres formes històriques i contemporànies de manejar els recursos naturals, confluint ¿amb la incorporació dels sabers locals i científics en Ciències Naturals- en l'Agroecologia. En tot aquest camí ha seguit de prop i col·laborat amb el SOC (Sindicato de Obreros del Campo), històrica i combativa associació de jornalers andalusos, i establert una xarxa internacional d'aliances acadèmiques i activistes en el camp dels estudis i les lluites camperoles. La seva aposta ¿com veurem tot seguit- és a favor d'un tipus d'investigació militant i pluriepistemològica.

Guidelines for Cleaning up Former Methamphetamine Labs, June 2009

Methamphetamine (meth) drug labs are not a new hazard to Iowa. In 2004, federal, state and local authorities seized more than 1,400 Iowa labs. These labs are discovered in houses, apartments, motel rooms, motor vehicles, and even an occasional combine. A dramatic decrease in the number of meth labs occurred in 2005 when a law restricting the purchase of pseudoephedrine was implemented. Although the number of meth labs has decreased, they continue to exist. Since there is currently no official federal guidance or regulations on how to clean up a former meth lab, the Iowa Department of Public Health, Division of Environmental Health, has created these basic guidelines to assist public health officials, property owners and the general public in cleaning up former meth lab properties.

2009-2011 Collective Bargaining Agreement Between State of Iowa and Local 893; Science Unit, July 1, 2009

This Agreement made and entered i into this 1 1st day of July 2009, at Des Moines, Iowa, pursuant to the provisions of Chapter 20 of the Iowa Code, by and between the State of Iowa (hereinafter referred to as the Employer) and UE Local 893/Iowa United Professionals, and its appropriate affiliated locals, as representatives of employees employed by the State of Iowa, as set forth specifically in Appendix A (hereinafter referred to as the Union).

2009-2011 Collective Bargaining Agreement Between State of Iowa and Local 893; Social Services, July 1, 2009

This Agreement made and entered i into this 1 1st day of July 2009, at Des Moines, Iowa, pursuant to the provisions of Chapter 20 of the Iowa Code, by and between the State of Iowa (hereinafter referred to as the Employer) and UE Local 893/Iowa United Professionals, and its appropriate affiliated locals, as representatives of employees employed by the State of Iowa.

Local acquisition of methicillin-resistance in predominant Staphylococcus aureus clones of western Switzerland.

Objectives: Recent population genetic studies suggest that the Staphylococcal Chromosome Cassettes mec (SCCmec) was acquired at a global scale much more frequently than previously thought. We hypothesized that such acquisitions can also be observed at a local level. In the present study, we aimed at investigating the diversity of SCCmec in a local MRSA population, where the dissemination of four MRSA clones has been observed (JCM 2007, 45: 3729). Methods: All the MRSA isolates (one per patient) recovered in the Vaud canton of Switzerland from January 2005 to December 2008 were analyzed in this study. We used the Double Locus Sequence Typing (DLST) method, based on clfB and spa loci, and the e-BURST algorithm to group the types with one allele in common (i.e. clone). To increase the discriminatory power of the DLST method, a third polymorphic marker (clfA) was further analyzed on a sub-sample of isolates. The SCCmec type of each isolate was determined with the first two PCRs of the Kondo scheme. Results: DLST analysis indicated that 1884/2036 isolates (92.5%) belong to the four predominant clones. A majority of isolates in each clone harboured an identical SCCmec type: 61/64 (95%) isolates to DLST clone 1−1 SCCmec IV, 1282/1323 (97%) to clone 2−2 SCCmec II, 237/288 (82%) to clone 3−3 SCCmec IV, and 192/209 (92%) to clone 4−4 SCCmec I. Unexpectedly, different SCCmec types were present in a single predominant DLST clone: SCCmec V plus one unusual type in 3 isolates of clone 1−1; SCCmec I, IV, V, VI plus two unusual types in 41 isolates of clone 2−2; SCCmec I, II, VI plus three unusual types in 51 isolates of clone 3−3; and SCCmec II, IV, V plus one unusual type in 17 isolates of clone 4−4. Interestingly, adding a third locus generally did not change the classification of incongruent SCCmec types, suggesting that these SCCmec elements have been acquired locally during the dissemination of the clones. Conclusion: Although the SCCmec diversity within clones was relatively low at a local level, a significant proportion of isolates with different SCCmec have been identified in the four major clones. This suggests that the local acquisition of SCCmec elements is not a rare event and illustrates the great capacity of S. aureus to quickly adapt to its environment by acquiring new genetic elements.

Informe sobre el Seminari «Sistemes d'Informació per a l'Acció Cultural Local» (Barcelona, 25-28 de novembre de 1998)

El passat mes de novembre, l'Àrea de Cultura de la Diputació de Barcelona va organitzar Interacció'98, unes jornades de convocatòria estatal sobre polítiques i gestió cultural. La convocatòria d'enguany ¿la quarta edició¿ tractà d'un centre d'interès específic: «Cultura i poder local». Dins el marc d'Interacció'98, es va organitzar el seminari de «Sistemes d'informació per a l'acció cultural local». Aquest seminari es va organitzar amb l'intent de conjugar la reflexió teòrica amb la presentació de pràctiques amb resultats positius procedents d'organitzacions públiques de diversa adscripció temàtica i sectorial de tot l'Estat espanyol. El comú denominador va ser la seva significació quant a les possibilitats i limitacions dels sistemes d'informació per a l'acció cultural a escala territorial.

Política local d'informació i biblioteca pública

S'analitza la relació entre la biblioteca pública i la política local d'informació. Es destaca la necessitat que les administracions desenvolupin, en l'àmbit local, sistemes d'informació per a sistematitzar i posar a disposició del ciutadà la informació generada des de l'Administració i d'altres agents municipals. Una de les funcions destacables de la biblioteca pública és facilitar l'accés a la informació. Això fa que la biblioteca tingui un paper clau en la participació en les polítiques locals d'informació. Es presenten exemples d'iniciatives vinculades a aquests àmbits i propostes d'actuació, tant per als ajuntaments com per a les pròpies biblioteques.

Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in ethiopia.

BACKGROUND: Cutaneous leishmaniasis is a vector-borne disease that is in Ethiopia mainly caused by the parasite Leishmania aethiopica. This neglected tropical disease is common in rural areas and causes serious morbidity. Persistent nonhealing cutaneous leishmaniasis has been associated with poor T cell mediated responses; however, the underlying mechanisms are not well understood. METHODOLOGY/PRINCIPAL FINDINGS: We have recently shown in an experimental model of cutaneous leishmaniasis that arginase-induced L-arginine metabolism suppresses antigen-specific T cell responses at the site of pathology, but not in the periphery. To test whether these results translate to human disease, we recruited patients presenting with localized lesions of cutaneous leishmaniasis and assessed the levels of arginase activity in cells isolated from peripheral blood and from skin biopsies. Arginase activity was similar in peripheral blood mononuclear cells (PBMCs) from patients and healthy controls. In sharp contrast, arginase activity was significantly increased in lesion biopsies of patients with localized cutaneous leishmaniasis as compared with controls. Furthermore, we found that the expression levels of CD3ζ, CD4 and CD8 molecules were considerably lower at the site of pathology as compared to those observed in paired PBMCs. CONCLUSION: Our results suggest that increased arginase in lesions of patients with cutaneous leishmaniasis might play a role in the pathogenesis of the disease by impairing T cell effector functions.