Síntese dos analgésicos paracetamol e fenacetina e do adoçante dulcina: um projeto para química orgânica experimental

A synthesis of artificial sweetener dulcin starting from nitrobenzene was elaborated for undergraduate organic laboratory course. Paracetamol and phenacetin, both physiologically active analgesic compounds, were also prepared as intermediates. Besides a large scope of discussion subjects related with organic synthesis, interesting lectures about analgesics and sweeteners may also be performed in this project. The advantage of this project is the adaptability according to the conditions offered by the course, i.e., convenience and/or availability of time and reagents.

Utilizando o monitoramento ambiental para o ensino da química: pedagogia de projeto

The article shows how the monitoring of the water quality can be utilized in an inter-disciplinary pedagogical project involving Analytical Chemistry, Biochemistry and Microbiology making the apprenticeship more dynamic and consolidating the link between the student and the community.

Management Estratégico. Su aplicación en la Gestión del Conocimiento y el Capital Humano

Es un libro en el que he tratado de destacar la cada día mayor vinculación existente entre las personas y el logro de la misión u objetivo supremo de la empresa. En la actualidad y en los próximos años, es imposible pensar que la empresa pueda alcanzar su misión sin una adecuada coordinación entre las personas y la estructura organizativa, teniendo en cuenta que el conocimiento es la base de todo ello lográndose a través de una determinada estrategia.

Cromatografando em coluna com resina de almécega: um projeto para química orgânica experimental

The use of natural products to demonstrate the silica gel column chromatography technique is proposed in the present article. It describes the separation of the triterpenes alpha- and beta-amirin from the diol breine and maniladiol, obtained from almécega resin (Protium heptaphyllum March.). The experiment uses an accessible material, was accomplished in 4 h, and can be applied with success an the experimental course of organic chemistry for undergraduate students.

Plan estratégico 2012-2105 para la empresa Automatizaciones Eléctricas, SL

La empresa moderna, se encuentra en una situación actual de incertidumbre en la que además está más expuesta a factores externos con el aumento de la competencia y el impacto de la globalización. Se enfrenta a un panorama que debe ser gestionado adecuadamente para asegurar su supervivencia y el éxito de su existencia. En este TFC, se presenta una de las herramientas ‘buque insignia’ del Management moderno, aquella que está destinada a ser la base de la Gestión de la empresa y que cada vez más se hace imprescindible para la construcción de un futuro cada vez más incierto, la Planificación Estratégica. El Plan Estratégico 2012-2015 de AESL se desarrolla en varios apartados que intentarán dar con las claves de la dirección que la empresa debe seguir y propone los objetivos que encontrará a través de la puesta en marcha de las acciones y estrategias determinadas. La primera etapa, y la más extensa, realiza un Análisis de la situación externa e interna de la empresa además de un Diagnóstico de la misma. Se analizan diversos factores que pueden contribuir o hacer peligrar el futuro de la empresa, y constituye el punto de partida de la planificación. En la segunda etapa, y con la información de la anterior fase, comienza la fijación de los Objetivos Corporativos y la definición de las Decisiones Estratégicas que han de transformar nuestro rumbo actual en el logro de esos objetivos. Las estrategias no sólo comportarán un ámbito corporativo, también se centrarán en estrategias funcionales con un carácter más definitorio en el interior de la empresa. Por último, la tercera y última etapa, aglutinará todas estas Decisiones estratégicas para transformarlas en las Decisiones Operativas, aquellas que se encargarán de gestionar el día a día de la empresa a través de los Planes de Acción, que suponen la etapa de mayor concreción del Plan. Este Plan a 3 años deberá erigirse como la herramienta de planificación más importante de la empresa, debiendo guiar las principales decisiones tomadas y convirtiéndose en un instrumento de consulta no sólo para decidir hoy lo que se hará en el futuro sino también para mantener unos niveles altos de competitividad en el tremendo esfuerzo que supone la gestión de una PYME.

De resíduo a insumo: a construção do caminho para uma química mais limpa através de um projeto de ensino

The discussion among teachers, students, and technicians about the destination of residues from chemistry laboratories led to a research project whose results were incorporated into a course in its daily practices. The treatment of the residues from argentimetric practices allowed us to establish cognitive relations of technological basis and of those related to the rising of the level of awareness about environmental aspects and social responsibility of chemistry professionals. The techniques and the results, from the economic point of view, namely that of value aggregation (metallic silver) and the conversion of the residue into input (potassium chromate solution) are shown.

Preparação do (+)-±-terpineol a partir do (+)-limoneno: monoterpenos de odor agradável em um projeto para química orgânica experimental

A synthesis of (+)-±-terpineol from (+)-limonene was proposed as a project for undergraduate organic laboratory course. Terpineol is a useful flavor and fragrance compound, and several aspects of this preparation are suited for experimental organic classes, including basic techniques for extraction and analyses of essential oils, different reaction types and the possibility of a high degree of student interest.

Projeto e construção de um picnômetro a ar para caracterização de insumos e produtos farmacêuticos

This paper describes a project, construction and test of a low cost air pycnometer, developed to be used preferentially in pharmaceutical research. A complete discussion of the construction, test and calibration of this equipment is presented and some measurements are made using pharmaceutical powders and dry granulations. The equipment performance has been estimated through its calibration curve, and the obtained value to its volume resolution is about 1%. This equipment is accomplished at the Applied Nuclear Physics Laboratory of University of Sorocaba (LAFINAU) in Sorocaba, SP, Brazil and it was denominated "Picnômetro a Ar Uniso - PICNAU".

Síntese de fotoprotetores e sua imobilização em poli(metacrilato de metilo): um projeto integrado de química orgânica, química de polímeros e fotoquímica

Dibenzalacetone and other aldol condensation products are known sunscreens commonly used in cosmetics. This type of compounds can easily be prepared in an Organic Chemistry Lab by reaction of aldehydes with ketones in basic medium. These compounds can be incorporated in poly(methyl methacrylate) and used as UV light absorbers, for example in sunglasses. This project has the advantage of using inexpensive reagents which are readily available in Chemistry Laboratories. This experiment can also be a base starting point for discussions of organic, polymer and photochemistry topics.

Resolução do ibuprofeno: um projeto para disciplina de química orgânica experimental

A practical and didactic sequence of experiments was proposed to illustrate the stereochemistry concept, optically active compounds, resolution of racemates, and use of the NMR technique, including 2D-COSY for identification of organic compounds, on a laboratory course for undergraduate students. The sequence was: extractions of racemic ibuprofen and chiral naproxen from commercial tablets; syntheses of diastereoisomeric amides reacting chiral (S)-(-)-α-methylbenzylamine with (±)-ibuprofen; separation and determination of absolute configuration of amides by ¹H NMR spectroscopy and GC analysis, and hydrolysis of amides to obtain (+)- and (-)-ibuprofen.

O projeto de educação instituído a partir de 1990: caminhos percorridos na formação de professores de química no Brasil

This paper presents and discusses governmental approaches to teacher training introduced in 1990, whose focus is the education of chemistry teachers. Therefore, the aim of this study was to establish the relationship between legal aspects and background needs present in the Brazilian educational context, taking into account that the last two decades has seen a significant increase in the chemistry licensure courses offered by higher education institutions in Brazil. Discussing these aspects of chemistry teachers provides a reflection on the real background needs for this group of professionals.

O problema da falácia naturalista para o projeto de uma ética evolucionista

Um dos problemas mais difíceis enfrentados pelos defensores de uma ética evolucionista é a falácia naturalista. Neste artigo, analisamos as soluções propostas por W. Rottschaefer e por R. Richards e verificamos não serem elas suficientes para eliminar o problema da falácia naturalista sem comprometer a especificidade da moral.

Condorcet e Kant: a esperança como horizonte do projeto político

Este trabalho analisa o conceito de esperança nas obras de Condorcet e Kant. Defende-se que o conceito de esperança no progresso da humanidade é de fundamental importância para a compreensão da filosofia política de ambos os autores. Por um lado, esperança oferece um horizonte de sentido que protege suas propostas políticas de visões de mundo antagônicas; por outro, ela se incorpora no próprio projeto político tendo ao mesmo tempo a função de motivação e de criação de instituições políticas com caráter pedagógico.