Understandings of transnational families in debates on Migration and development

International migration sets in motion a range of significant transnational processes that connect countries and people. How migration interacts with development and how policies might promote and enhance such interactions have, since the turn of the millennium, gained attention on the international agenda. The recognition that transnational practices connect migrants and their families across sending and receiving societies forms part of this debate. The ways in which policy debate employs and understands transnational family ties nevertheless remain underexplored. This article sets out to discern the understandings of the family in two (often intermingled) debates concerned with transnational interactions: The largely state and policydriven discourse on the potential benefits of migration on economic development, and the largely academic transnational family literature focusing on issues of care and the micro-politics of gender and generation. Emphasizing the relation between diverse migration-development dynamics and specific family positions, we ask whether an analytical point of departure in respective transnational motherhood, fatherhood or childhood is linked to emphasizing certain outcomes. We conclude by sketching important strands of inclusions and exclusions of family matters in policy discourse and suggest ways to better integrate a transnational family perspective in global migration-development policy.

Eclipses, razón y superstición en las vidas de Nicias y Dión de Plutarco

A partir de un abordaje retórico-literario, nuestro objetivo es indagar las representaciones discursivas de los elementos supersticiosos en la biografía de Nicias y en la de Dión. Tomaremos como ejemplo el eclipse de luna narrado en Nicias 23 y reiterado en Dión 24, para demostrar que mediante la repetición del ejemplo en dos contextos distintos Plutarco nos invita a reflexionar sobre la superstición de un modo más atractivo que la mera exposición teórica de doctrinas filosóficas.

La prioridad del Igualitarismo Democrático

Este artículo mostrará que las versiones estrictas del Igualitarismo Democrático y del Igualitarismo de la Suerte son implausibles ya que defienden una visión monista del objeto de la justicia igualitaria. Por el contrario, sus versiones moderadas son aceptables ya que admiten la composición plural del objeto de justicia igualitaria.Esta comprensión plural exige, sin embargo, el establecimiento de prioridades normativas ya que las exigencias de cada valor entran típicamente en conflicto. Aquí, se ofrecerán tres argumentos para defender la prioridad del Igualitarismo Democrático sobre el Igualitarismo de la Suerte: uno instrumental, otro relacionado con el significado expresivo de las políticas públicas estatales y un último que justifica la división del trabajo moral igualitarista.

Sanctity of Human Life in the Context of Human Genetic Research

The study on the concept of sanctity of human life is a journey in finding out what is it said to be “human” in human life. It is an evaluation of the universal concept and the role it plays in controlling and moulding human conduct and relationships. This concept is a foundational principle of human rights law and the grundnorm of every legal system. However, of late, the challenges by way of certain advances in human genetic research had prompted the need to evaluate the significance and extent of the concept in human endeavours. Scientific advances by way of human genetic research promises significant diagnostic and therapeutic advances but at the same time pose threat to fundamental notions and assumptions on humanity, hence there is a global concern to derive common legal standards, Thus the major challenge is to analyse universal principles which can be a common criteria for evolving legal standards to control certain advances in human genetic research. Hence the relevance of the study. The study aims at analysing the content, scope, extent and limitation of the concept of sanctity of human life. In this attempt it evaluates the extent to which the concept had been accommodated by legal systems and international human rights regimes. The problem which had been undertaken in the study is the extent of intrusion made to the concept by virtue of certain advances in human genetic research.

O Sistema de Gestão e Avaliação do Desempenho na Administração Pública Portuguesa: efeitos da sua prática no contrato psicológico dos colaboradores

Desde as últimas décadas do século XX que, perante um cenário marcado pela complexidade de uma economia globalizada, a Administração Pública tem sido coagida a passar por processos de reforma. As referências à reestruturação da Administração Pública por motivos políticos, económicos e financeiros, são frequentes na literatura, e surgem, quase sempre, num discurso imperativo. Neste contexto, foram introduzidos mecanismos de mercado por se acreditar que estes produzem soluções mais eficazes para o cidadão-cliente, uma administração motivadora, para quantos nela trabalham, e eficiência económica. Na esfera pública, mais do que transformar inputs em outputs, importa, avaliar os outcomes, isto é, o impacto sobre o valor público. Inúmeros estudos concorreram para enquadrar e justificar a reforma do sector público. Continuam, porém, a faltar respostas de como compatibilizar a gestão orçamental com práticas ideológicas das organizações, nomeadamente ao nível da gestão de recursos humanos. Este estudo tem como objectivo central contribuir para um melhor conhecimento dos efeitos que a prática da avaliação do desempenho, em vigor na Administração Pública Portuguesa, tem no contrato psicológico dos colaboradores. Para o teste das hipóteses propusemos um modelo de investigação, tomando como referência a teoria de Guest. Com uma abordagem qualitativa, construímos um inquérito por questionário, que foi aplicado a alguns colaboradores de uma Instituição pública. Os dados recolhidos permitiram a elaboração de quadros de referência de resultados que, por meio da análise de conteúdo, nos possibilitou tirar ilações acerca do comprometimento organizacional e comportamentos de cidadania organizacional dos Colaboradores. Trata-se de uma pesquisa com características exploratórias que, acreditamos, possa ser a base para trabalhos futuros sobre os efeitos do SIADAP nos indivíduos e nas organizações. Os resultados mostram que o sentimento de que a organização não cumpriu os termos do contrato psicológico é moderado por um esforço emocional, que mantém o colaborador na organização, evidenciando, ainda, um comprometimento afectivo com a Instituição e comportamentos de virtude cívica. / Since the last decades of the 20th century, in a scenario marked by the complexity of a globalized economy, the Public Administration has been forced to undergo reform processes. References to the restructuring of the Public Administration for political, economical and financial reasons are frequent in literature, and arise, in most cases, in an imperative tone. In this context, market mechanisms were introduced, as it is believed that they produce more efficient solutions for the citizen-client, motivated administration for whom many work, and economic efficiency. In the public sphere, more than just transforming inputs into outputs, it is important to evaluate the outcomes, that is, the impact on the public value. Numerous studies have contributed to contextualize and justify the public sector reform. However, there are still no answers of how to develop compatibility between the budgetary management and the ideological practices of the organizations, namely on the level of human resource management. The main aim of this study is to contribute to a better knowledge of the effects that the practice of performance appraisal, in force in the Portuguese Public Administration, has on the employee's psychological contract. For this hypothesis test, we proposed a research model, with reference to Guest's theory. With a qualitative approach, we constructed a survey questionnaire that was applied to some employees of a Public Institution. The data gathered allowed the elaboration of results frameworks which, by means of the content analysis, enabled us to draw conclusions of the employees' organizational commitment and organizational citizenship behaviour. It is a research with exploratory characteristics, which we believe, may provide the basis for future work on the effects of the SIADAP on individuals and organizations. The results indicate that the feeling that the organization did not fulfil the psychological contract terms is moderated by an emotional effort, which leads the employee to remain in the organization, also showing an affective commitment to the institution and civic virtue behaviours.

Coimbra: cidade amiga das pessoas idosas?!

Introdução: Em Portugal, bem como nos restantes países mundiais, tem sido registado, em virtude de múltiplas transformações societárias, um aumento crescente do envelhecimento demográfico. Este novo cenário demográfico originou uma reflexão, por parte de organizações supranacionais, sobre as cidades na sua relação com os munícipes mais velhos. Desta reflexão surge o projeto Cidade Amiga das Pessoas Idosas que apresenta referenciais de avaliação das cidades para que estas possam adaptar as suas estruturas e serviços aos seus munícipes mais velhos. Beneficiando desta forma do potencial que as pessoas mais velhas representam para a humanidade. Objetivos: O presente estudo tem como objetivo central verificar se a cidade de Coimbra é uma cidade amiga das pessoas idosas. Metodologia: A pesquisa remete para um estudo qualitativo exploratório a partir dos procedimentos metodológicos que constam do Protocolo de Vancouver. O focus group decorreu em duas sessões. Participantes: Foram auscultados 16 pessoas, 15 (93,8%) do sexo feminino. A idade média situa-se nos 79,88 anos (dp= ± 10,658), são maioritariamente viúvos (7= 43,8 %) e 7 (43,8%) e têm como habilitações a 4ª classe. Autoclassificam-se maioritariamente na classe média baixa (7 =43,8). Resultados: Das oito categorias analisadas três categorias “espaços exteriores e edifícios”, “transportes” e “respeito e inclusão social” são avaliadas com aspetos positivos e negativos. O “suporte comunitário e serviços de saúde” é avaliado como positivo enquanto a “habitação”, “participação social” e “comunicação e informação” são avaliados como negativos. As sugestões efetuadas referem-se a um único tópico “espaços exteriores e edifícios”. Conclusões: Se partilharmos a tese que uma cidade amiga das pessoas idosas estimula o envelhecimento ativo porque otimiza as oportunidades de participação no ambiente urbano melhorando, desta forma, a qualidade de vida das pessoas envelhecem. Os resultados que obtivemos, a partir da auscultação de um grupo de idosos, permitem-nos afirmar que Coimbra precisa de se adaptar aos seus munícipes mais velhos. Só assim Coimbra se poderá tornar uma cidade amiga das pessoas idosas. Importa igualmente registar que os resultados encontrados devem ser mediados pelo perfil sociodemográfico dos idosos entrevistados. / Introduction: In Portugal, as well as in other countries worldwide, has been registered by virtue of multiple associated transformations, an increasing growing of population. This new demographic scenario triggered, led to a reflection on the part of supranational organizations, about the cities in their relationship with the older residents. This reflection comes with the project Friendly City of Older Persons that presents benchmarks for the evaluation of cities so that they can adapt their structures and services to its older citizens. Enjoying this way the potential that older people represent for humanity. Objectives: This study aims to check if the city of Coimbra is an elderly friendly city. Methodology: The research refers to an exploratory qualitative study from the methodological procedures of the Vancouver Protocol. The focus group was held in two sessions. Participants: 16 people were sounded out, 15(93.8%) were female. The average ages tends at79.88 years (dp = ±10,658), are mostly widowers (7=43.8%) and 7 (43.8%) have the qualifications to4th grade. They are classified mostly in the lower middle class(7=43.8). Results: Of the eight analyzed categories three categories" outdoor spaces and buildings", "transport" and "respect and social inclusion" are evaluated on positive and negative aspects. The "community support and health services" is evaluated as positive as the"housing", "social participation "and "communication and information" are evaluated as negative. The suggestions are related to a single topic "buildings and outdoor areas." Conclusions: If we share the view that an elderly friendly citizen courages active aging because it optimizes the opportunities for participation in the urban environment improving, in this manner, the quality of life of the elderly. The results we obtained from the consultation of a group of elderly allow us to say that Coimbra needs to adapt to its older citizens. Only then Coimbra can become a friendly city of the elderly. It should also be noted that the results should be mediated by socio-demographic profile of elderly respondents.

Virtuous Activity Is Sufficient for Happiness and Some Minimally Favorable Circumstances Are Necessary for Virtuous Activity

Thesis (Ph.D.)--University of Washington, 2016-08

Synergistic nisin-polymyxin combinations for the control of Pseudomonas biofilm formation

The emergence and dissemination of multi-drug resistant pathogens is a global concern. Moreover, even greater levels of resistance are conferred on bacteria when in the form of biofilms (i.e., complex, sessile communities of bacteria embedded in an organic polymer matrix). For decades, antimicrobial peptides have been hailed as a potential solution to the paucity of novel antibiotics, either as natural inhibitors that can be used alone or in formulations with synergistically acting antibiotics. Here, we evaluate the potential of the antimicrobial peptide nisin to increase the efficacy of the antibiotics polymyxin and colistin, with a particular focus on their application to prevent biofilm formation of Pseudomonas aeruginosa. The results reveal that the concentrations of polymyxins that are required to effectively inhibit biofilm formation can be dramatically reduced when combined with nisin, thereby enhancing efficacy, and ultimately, restoring sensitivity. Such combination therapy may yield added benefits by virtue of reducing polymyxin toxicity through the administration of significantly lower levels of polymyxin antibiotics.

Diseño de una herramienta modular que facilite la implementación del Banco de Proyectos de la Fundación Red de Apoyo Social de Antioquia – RASA, ubicado en la ciudad de Medellín, entre el periodo 2014-2 y 2015-1

Los usuarios reales y potenciales del sistemas de salud en Colombia, encuentran en el camino de acceso a los servicios múltiples barreras, debido a las diferentes carencias que éste sistema presenta. Para apoyar las necesidades del usuario en éste tema de acceso, se constituyó en el año 2006 la Fundación RASA, quien ofrece de manera gratuita, a la comunidad en general, mecanismos de exigibilidad, acceso y protección de sus derechos en temas de salud. Este trabajo de grado, pretende dar un valor agregado diseñando una herramienta modular que facilite la implementación del banco de proyectos, con el fin de mejorar sus procesos y sea referencia para otras entidades dedicadas a velar por el bienestar de los individuos, en virtud de su objeto social orientado a la protección de derechos en temas de salud, además se realiza con el fin de Optar por el Título de Especialista en Alta Gerencia de la Universidad de Medellín. Con el fin de entender las necesidades de La Fundación RASA, será primordial conocer y tener un manejo adecuado de la teoría de la organización; teniendo clara su vertiente descriptiva que sugiere lo que se debe hacer para mejorar varios aspectos de la empresa, en éste caso la necesidad de diseñar un Banco de Proyectos. El trabajo se ha estructurado de la siguiente manera: Referente Teórico, Contextualización De La Fundación Rasa, Diseño De Una Herramienta Modular (Introducción, Objetivos, Recursos, Metodología y procedimientos, Evaluación y Monitoreo, Responsable de proceso, Presupuesto Estructural), Conclusiones y Recomendaciones.

Analysis of Molecular Dynamics Simulations of Protein Folding

Microsecond long Molecular Dynamics (MD) trajectories of biomolecular processes are now possible due to advances in computer technology. Soon, trajectories long enough to probe dynamics over many milliseconds will become available. Since these timescales match the physiological timescales over which many small proteins fold, all atom MD simulations of protein folding are now becoming popular. To distill features of such large folding trajectories, we must develop methods that can both compress trajectory data to enable visualization, and that can yield themselves to further analysis, such as the finding of collective coordinates and reduction of the dynamics. Conventionally, clustering has been the most popular MD trajectory analysis technique, followed by principal component analysis (PCA). Simple clustering used in MD trajectory analysis suffers from various serious drawbacks, namely, (i) it is not data driven, (ii) it is unstable to noise and change in cutoff parameters, and (iii) since it does not take into account interrelationships amongst data points, the separation of data into clusters can often be artificial. Usually, partitions generated by clustering techniques are validated visually, but such validation is not possible for MD trajectories of protein folding, as the underlying structural transitions are not well understood. Rigorous cluster validation techniques may be adapted, but it is more crucial to reduce the dimensions in which MD trajectories reside, while still preserving their salient features. PCA has often been used for dimension reduction and while it is computationally inexpensive, being a linear method, it does not achieve good data compression. In this thesis, I propose a different method, a nonmetric multidimensional scaling (nMDS) technique, which achieves superior data compression by virtue of being nonlinear, and also provides a clear insight into the structural processes underlying MD trajectories. I illustrate the capabilities of nMDS by analyzing three complete villin headpiece folding and six norleucine mutant (NLE) folding trajectories simulated by Freddolino and Schulten [1]. Using these trajectories, I make comparisons between nMDS, PCA and clustering to demonstrate the superiority of nMDS. The three villin headpiece trajectories showed great structural heterogeneity. Apart from a few trivial features like early formation of secondary structure, no commonalities between trajectories were found. There were no units of residues or atoms found moving in concert across the trajectories. A flipping transition, corresponding to the flipping of helix 1 relative to the plane formed by helices 2 and 3 was observed towards the end of the folding process in all trajectories, when nearly all native contacts had been formed. However, the transition occurred through a different series of steps in all trajectories, indicating that it may not be a common transition in villin folding. The trajectories showed competition between local structure formation/hydrophobic collapse and global structure formation in all trajectories. Our analysis on the NLE trajectories confirms the notion that a tight hydrophobic core inhibits correct 3-D rearrangement. Only one of the six NLE trajectories folded, and it showed no flipping transition. All the other trajectories get trapped in hydrophobically collapsed states. The NLE residues were found to be buried deeply into the core, compared to the corresponding lysines in the villin headpiece, thereby making the core tighter and harder to undo for 3-D rearrangement. Our results suggest that the NLE may not be a fast folder as experiments suggest. The tightness of the hydrophobic core may be a very important factor in the folding of larger proteins. It is likely that chaperones like GroEL act to undo the tight hydrophobic core of proteins, after most secondary structure elements have been formed, so that global rearrangement is easier. I conclude by presenting facts about chaperone-protein complexes and propose further directions for the study of protein folding.

'Expanding Horizons': investigating the Glasgow 2014 legacy for young people in the East End of Glasgow

The recent staging of Glasgow 2014 drew universal praise as the ‘Best Games Ever’. Yet the substantial undertaking of hosting the Commonwealth Games (CWG) was sold to the nation as more than just eleven days of sporting spectacle and cultural entertainment. Indeed, the primary strategic justification offered by policymakers and city leaders was the delivery of a bundle of positive and enduring benefits, so-called ‘legacy’. This ubiquitous and amorphous concept has evolved over time to become the central focus of contemporary hosting bids, reflecting a general public policy shift towards using major sporting mega events as a catalyst to generate benefits across economic, environmental and social dimensions, on a scale intended to be truly transformative. At the same time, the academy has drawn attention to the absence of evidence in support of the prevailing legacy rhetoric and raised a number of sociological concerns, not least the socially unequitable distribution of purported benefits. This study investigated how young people living in the core hosting zone related to, and were impacted upon, by the CWG and its associated developments and activities with reference to their socio-spatial horizons, the primary outcome of interest. An ‘ideal world’ Logic Model hypothesised that four mechanisms, identified from official legacy documents and social theories, would alter young people’s subjective readings of the world by virtue of broadening their social networks, extending their spatial boundaries and altering their mind sets. A qualitative methodology facilitated the gathering of situated and contextualised accounts of young people’s attitudes, perceptions, beliefs and behaviours relating to Glasgow 2014. In-depth interviews and focus groups were conducted before and after the Games with 26 young people, aged 14-16 years, at two schools in the East End. This approach was instrumental in privileging the interests of people ‘on the ground’ over those of city-wide and national stakeholders. The findings showed that young people perceived the dominant legacy benefit to be an improved reputation and image for Glasgow and the East End. Primary beneficiaries were identified by them as those with vested business interests e.g. retailers, restaurateurs, and hoteliers, as well as national and local government, with low expectations of personal dividends or ‘trickle down’ benefits. Support for Glasgow 2014 did not necessarily translate into individual engagement with the various cultural and sporting activities leading up to the CWG, including the event itself. The study found that young people who engaged most were those who had the ability to ‘read’ the opportunities available to them and who had the social, cultural and economic capital necessary to grasp them, with the corollary that those who might have gained most were the least likely to have engaged with the CWG. Doubts articulated by research participants about the social sustainability of Glasgow 2014 underscored inherent tensions between the short-lived thrill of the spectacle and the anticipated longevity of its impacts. The headline message is that hosting sporting mega events might not be an effective means of delivering social change. Aspirant host cities should consider more socially equitable alternatives to sporting mega events prior to bidding; and future host cities should endeavour to engage more purposefully with more young people over longer time frames.

Post-shock thermochemistry in hypervelocity CO2 and air flow

This work represents ongoing efforts to study high-enthalpy carbon dioxide flows in anticipation of the upcoming Mars Science Laboratory (MSL) and future missions to the red planet. The work is motivated by observed anomalies between experimental and numerical studies in hypervelocity impulse facilities for high enthalpy carbon dioxide flows. In this work, experiments are conducted in the Hypervelocity Expansion Tube (HET) which, by virtue of its flow acceleration process, exhibits minimal freestream dissociation in comparison to reflected shock tunnels. This simplifies the comparison with computational result as freestream dissociation and considerable thermochemical excitation can be neglected. Shock shapes of the MSL aeroshell and spherical geometries are compared with numerical simulations incorporating detailed CO2 thermochemical modeling. The shock stand-off distance has been identified in the past as sensitive to the thermochemical state and as such, is used here as an experimental measurable for comparison with CFD and two different theoretical models. It is seen that models based upon binary scaling assumptions are not applicable for the low-density, small-scale conditions of the current work. Mars Science Laboratory shock shapes at zero angle of attack are also in good agreement with available data from the LENS X expansion tunnel facility, confi rming results are facility-independent for the same type of flow acceleration, and indicating that the flow velocity is a suitable first-order matching parameter for comparative testing. In an e ffort to address surface chemistry issues arising from high-enthalpy carbon dioxide ground-test based experiments, spherical stagnation point and aeroshell heat transfer distributions are also compared with simulation. Very good agreement between experiment and CFD is seen for all shock shapes and heat transfer distributions fall within the non-catalytic and super-catalytic solutions. We also examine spatial temperature profiles in the non-equilibrium relaxation region behind a stationary shock wave in a hypervelocity air Mach 7.42 freestream. The normal shock wave is established through a Mach reflection from an opposing wedge arrangement. Schlieren images confirm that the shock con guration is steady and the location is repeatable. Emission spectroscopy is used to identify dissociated species and to make vibrational temperature measurements using both the nitric oxide and the hydroxyl radical A-X band sequences. Temperature measurements are presented at selected locations behind the normal shock. LIFBASE is used as the simulation spectrum software for OH temperature-fitting, however the need to access higher vibrational and rotational levels for NO leads to the use of an in-house developed algorithm. For NO, results demonstrate the contribution of higher vibrational and rotational levels to the spectra at the conditions of this study. Very good agreement is achieved between the experimentally measured NO vibrational temperatures and calculations performed using an existing state-resolved, three-dimensional forced harmonic oscillator thermochemical model. The measured NO A-X vibrational temperatures are significantly higher than the OH A-X temperatures.

El filosofar iuspoli(é)tico equitativista. (Una tentativa de Filosofía Política de la moral y el derecho)

Este ensayo teoriza la relaciones fuertes que toda praxis política tiene de forma consciente o inconsciente con alguna concepción concreta de la moral y del derecho. Trata así de explicitar esos vínculos en el marco de una filosofía crítica de la política, bajo la denominación de ‘poli(é)tica’ e ‘iuspoli(é)tica’ general. Para ello analiza la presencia de la actitud moral y la norma jurídica en la acción política. Estas relaciones se considera que pueden ser representadas de una forma «romboidal» más que «triangular», en virtud de la duplicidad de rasgos constituyentes / instituyentes y constituidos / instituidos de toda política respecto a las diversas concepciones de la moral y el derecho. En relación a ‘lo peor fáctico’ y ‘lo mejor posible’, construidos desde la interpretación de lo real como modelos de validez y viabilidad ejemplar negativa y positiva, finalmente se reformula la categoría de ‘autonomía’ en sus versiones iuspoli(é)ticas autodeterminista, pluriversalista y finalista y sus vertientes individual y societal. Emerge de esta manera una propuesta de filosofía iuspoli(é)tica equitativista particular que pivota sobre las categorías de legitimidad, dignidad, autonomía y equidad.

Na granicy Unii Europejskiej – pozycja europejskich terytoriów autonomicznych w dobie globalizacji i integracji. Przypadek Wysp Alandzkich

The model of autonomy developed by the Aland Isles can provide a number of interesting solutions applicable in other territories. Territorial autonomy as a manner of ensuring the political and economic rights of the minority involves facing up to the challenges of European integration and globalization. It seems that the Aland Isles have successfully coped with this challenge. Firstly, they were able to present and promote their own interests during the accession negotiations in an efficient manner. Secondly, they maintained (and additionally strengthened by including it in the aquis communitaire) their separate, autonomous status and the guarantees of identity protection by virtue of limiting the rights of persons without domicile rights to purchase land and run business activity. Thirdly, they managed to obtain a special status excluding them from the process of indirect tax harmonization, thus ensuring considerable economic benefits. Fourthly, both Finland and the European Union confirmed their autonomy, demilitarization and neutrality allowing the Isles to retain their former status under the new circumstances. Fifthly, they obtained representation in the Committee of the Regions and a defined position on European matters in Finland. The skillful application of the existing solutions and the winning of an advantageous set of derogations and exceptions strengthened the position of the Isles both with respect to Finland and the international surroundings. The Isles’ economic, cultural and political protection was augmented. Alongside their participation in international organizations, such as The Nordic Board, the Aland Isles have remained active and discernible on the international arena.

Olhar supervisivo sobre a liderança escolar

Trabalho de projeto apresentado à Escola Superior de Educação de Paula Frassinetti para obtenção do grau de Mestre em Ciências da Educação Especialização em Supervisão Pedagógica